Compounds > 1-(5-isoquinolinesulfonyl)-2-methylpiperazine

1-(5-isoquinolinesulfonyl)-2-methylpiperazine and arginine

1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with arginine in 11 studies

Research

Studies (11)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	9 (81.82)	18.2507
2000's	1 (9.09)	29.6817
2010's	1 (9.09)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Day, RW; Ignarro, LJ; Klitzner, TS; Lai, WW	1
Cha, T; Ikegami, H; Noma, Y; Ogihara, T; Shima, K; Tahara, Y; Yamato, E; Yoneda, H	1
Craven, PA; DeRubertis, FR; Studer, RK	1
Coderre, TJ; Yashpal, K	1
Clegg, JM; McKenna, TM; Williams, TJ	1
Diamond, SL; Ranjan, V; Xiao, Z	1
Dharmarajan, AM; Kugu, K; Preutthipan, S; Wallach, EE	1
Komori, K; Sugimoto, M; Yamanouchi, D	1
Gonon, AT; Kiss, A; Pernow, J; Sjöquist, PO; Tratsiakovich, Y; Yang, J	1
Bertrand, R; Jenkins, J; Pommier, Y; Solary, E	1
Abend, M; Frombeck, S; Van Beuningen, D	1

Reviews

1 review(s) available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and arginine

Article	Year
Therapeutic approach against intimal hyperplasia of vein grafts through endothelial nitric oxide synthase/nitric oxide (eNOS/NO) and the Rho/Rho-kinase pathway. Surgery today, 2009, Volume: 39, Issue:6 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adrenergic beta-Antagonists; Animals; Arginine; Cell Movement; Cell Proliferation; Endothelium, Vascular; Gene Transfer Techniques; Genetic Therapy; Graft Occlusion, Vascular; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperplasia; Nitric Oxide; Nitric Oxide Synthase Type III; Protein Kinase Inhibitors; rho-Associated Kinases; Transplantation, Autologous; Tunica Intima; Up-Regulation	2009

Article

Year

Therapeutic approach against intimal hyperplasia of vein grafts through endothelial nitric oxide synthase/nitric oxide (eNOS/NO) and the Rho/Rho-kinase pathway.

Surgery today, 2009, Volume: 39, Issue:6

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adrenergic beta-Antagonists; Animals; Arginine; Cell Movement; Cell Proliferation; Endothelium, Vascular; Gene Transfer Techniques; Genetic Therapy; Graft Occlusion, Vascular; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperplasia; Nitric Oxide; Nitric Oxide Synthase Type III; Protein Kinase Inhibitors; rho-Associated Kinases; Transplantation, Autologous; Tunica Intima; Up-Regulation

2009

Other Studies

10 other study(ies) available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and arginine

Article	Year
Oxygen-mediated regulation of neonatal and adult rabbit aortic tension. Developmental pharmacology and therapeutics, 1992, Volume: 19, Issue:2-3 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Aging; Animals; Aorta; Arginine; Endothelium, Vascular; Enzyme Activation; In Vitro Techniques; Isoquinolines; Muscle Contraction; Muscle Development; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Oxygen; Piperazines; Potassium Chloride; Protein Kinase C; Rabbits	1992
Role of protein kinase C in the regulation of glucagon gene expression by arginine. Biochemical and biophysical research communications, 1990, Sep-14, Volume: 171, Issue:2 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arginine; Cells, Cultured; Gene Expression Regulation; Glucagon; Islets of Langerhans; Isoquinolines; Kinetics; Male; Piperazines; Proglucagon; Protein Kinase C; Protein Precursors; Rats; Rats, Inbred Strains; RNA, Messenger	1990
Impaired nitric oxide-dependent cyclic guanosine monophosphate generation in glomeruli from diabetic rats. Evidence for protein kinase C-mediated suppression of the cholinergic response. The Journal of clinical investigation, 1994, Volume: 93, Issue:1 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Alkaloids; Amino Acid Oxidoreductases; Animals; Arginine; Calcimycin; Carbachol; Cyclic GMP; Diabetes Mellitus, Experimental; Female; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Isoquinolines; Kidney Glomerulus; Kinetics; Membrane Proteins; Myristoylated Alanine-Rich C Kinase Substrate; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Phosphates; Phosphorylation; Piperazines; Prostaglandin Endoperoxides, Synthetic; Protein Kinase C; Proteins; Rats; Rats, Sprague-Dawley; Staurosporine; Thromboxane A2	1994
Intracellular messengers contributing to persistent nociception and hyperalgesia induced by L-glutamate and substance P in the rat formalin pain model. The European journal of neuroscience, 1994, Aug-01, Volume: 6, Issue:8 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arachidonic Acid; Arginine; Dexamethasone; Formaldehyde; Glutamic Acid; Hyperalgesia; Injections, Spinal; Isoquinolines; Male; Neurotransmitter Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nociceptors; Pain; Pain Measurement; Pain Threshold; Piperazines; Protein Kinase C; Rats; Reflex; Substance P	1994
Protein kinase C is a mediator of lipopolysaccharide-induced vascular suppression in the rat aorta. Shock (Augusta, Ga.), 1994, Volume: 2, Issue:2 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amino Acid Oxidoreductases; Animals; Aorta; Arginine; Cell Membrane; Citrulline; Cycloheximide; Cytosol; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Isoquinolines; Kinetics; Lipopolysaccharides; Male; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phorbol 12,13-Dibutyrate; Piperazines; Potassium Chloride; Protein Kinase Inhibitors; Protein Kinases; Rats; Rats, Sprague-Dawley; Stereoisomerism; Sulfonamides	1994
Constitutive NOS expression in cultured endothelial cells is elevated by fluid shear stress. The American journal of physiology, 1995, Volume: 269, Issue:2 Pt 2 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amino Acid Oxidoreductases; Animals; Arginine; Arteries; Base Sequence; Cattle; Cells, Cultured; Dexamethasone; Endothelium, Vascular; Gene Expression Regulation; Humans; Isoquinolines; Molecular Sequence Data; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Piperazines; Protein Kinase C; RNA, Messenger; Stress, Mechanical; Veins	1995
Role of calcium/calmodulin-dependent protein kinase II in gonadotrophin-induced ovulation in in vitro perfused rabbit ovaries. Journal of reproduction and fertility, 1995, Volume: 103, Issue:2 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arachidonic Acids; Arginine; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Chorionic Gonadotropin; Dinoprost; Female; In Vitro Techniques; Isoquinolines; NG-Nitroarginine Methyl Ester; Nitric Oxide; Ovary; Ovulation; Perfusion; Piperazines; Progesterone; Rabbits; Signal Transduction	1995
Inhibition of Rho kinase protects from ischaemia-reperfusion injury via regulation of arginase activity and nitric oxide synthase in type 1 diabetes. Diabetes & vascular disease research, 2017, Volume: 14, Issue:3 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arginase; Arginine; Cytoprotection; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Drug Therapy, Combination; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide Synthase; omega-N-Methylarginine; Protein Kinase Inhibitors; Rats, Sprague-Dawley; rho GTP-Binding Proteins; rho-Associated Kinases; Signal Transduction	2017
Apoptosis and its modulation in human promyelocytic HL-60 cells treated with DNA topoisomerase I and II inhibitors. Experimental cell research, 1993, Volume: 207, Issue:2 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Aminoquinolines; Aphidicolin; Apoptosis; Benzamides; Calcium; Calmodulin; Camptothecin; Cell Cycle; Chromatin; Cyclosporine; DNA; Egtazic Acid; Ethers, Cyclic; Humans; Isoquinolines; Leukemia, Experimental; Leukemia, Promyelocytic, Acute; Microscopy, Electron; Naphthalenes; Okadaic Acid; Phosphoprotein Phosphatases; Piperazines; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerase Inhibitors; Polycyclic Compounds; Protein Kinase C; Spermine; Staurosporine; Teniposide; Tetradecanoylphorbol Acetate; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured; Zinc	1993
Indications for an active process underlying spontaneous and radiation-induced micronucleation in L929 cells. International journal of radiation biology, 1999, Volume: 75, Issue:12 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Aurintricarboxylic Acid; Benzhydryl Compounds; Bromodeoxyuridine; Cell Division; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; DNA, Neoplasm; Electrophoresis, Gel, Pulsed-Field; Endonucleases; Enzyme Inhibitors; Fibrosarcoma; Mice; Micronuclei, Chromosome-Defective; Micronucleus Tests; Proliferating Cell Nuclear Antigen; Protein Kinase C; Spermine; Sphingosine; Teniposide; Topoisomerase II Inhibitors; Transcription, Genetic; Tumor Cells, Cultured	1999