1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with amiloride in 41 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (19.51) | 18.7374 |
| 1990's | 31 (75.61) | 18.2507 |
| 2000's | 1 (2.44) | 29.6817 |
| 2010's | 1 (2.44) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Horiguchi, M; Kuriyama, S; Nakamura, K; Sakai, O; Uchida, H | 1 |
| Cragoe, EJ; Haddad, P; Haman, A; Hoang, T; Rajotte, D | 1 |
| Inoue, T; Morita, T; Okuhama, R; Sera, M; Tominaga, N; Ueki, H | 1 |
| Obara, K; Usuki, T; Yabu, H | 1 |
| Hamm, LL; Herndon, J; Vehaskari, VM | 1 |
| Althaus, HH; Klöppner, S; Neuhoff, V; Rohmann, A; Schröter, J; Schwartz, P; Spoerri, P | 1 |
| Gupta, A; Renfro, JL | 1 |
| Khan, NA; Moulinoux, JP; Quemener, V | 1 |
| Cragoe, EJ; Hori, M; Iwakura, K; Kamada, T; Kitabatake, A; Watanabe, Y; Yoshida, H | 1 |
| Hendey, B; Mamrack, MD | 1 |
| Gottlieb, RA; Jiang, WP; Kinsey, WH; Lennarz, WJ | 1 |
| Cragoe, EJ; Hara, M; Inagaki, C; Inoue, M; Omori, K; Otani, H; Uriu, T | 1 |
| Kim, S; Koh, E; Miyashita, Y; Morimoto, S; Nabata, T; Ogihara, T | 1 |
| Bollinger, DW; Franklin, CC; Kim, HD; Turner, JT | 1 |
| Hansen, HS; Jensen, B; Linnebjerg, H | 1 |
| Hoffmann, A; Klöcking, HP | 1 |
| Ardaillou, R; Baud, L; Cherqui, G; Cragoe, EJ; Perez, J | 1 |
| Linebaugh, BE; Rillema, JA; Tarrant, TM | 1 |
| Beattie, LL; Cragoe, EJ; Gerrard, JM; Israels, SJ; Lint, D; McNicol, A; Park, J | 1 |
| Souhrada, JF; Souhrada, M | 2 |
| Cragoe, EJ; Minakami, S; Satoh, M; Sumimoto, H; Takeshige, K | 1 |
| Kuroki, T; Nose, K; Shibanuma, M | 1 |
| Azimi, S; Hamdani, S; Laborde, K; Sachs, C; Shahedi, M | 1 |
| Fusamoto, H; Hayashi, N; Horimoto, M; Ito, T; Kamada, T; Kaneko, A; Sasaki, Y; Tanaka, Y | 1 |
| Collado-Escobar, D; Mollinedo, F; Pérez-Sala, D | 1 |
| Fusamoto, H; Hayashi, N; Horimoto, M; Ito, T; Kamada, T; Kaneko, A; Kasahara, A; Sasaki, Y; Tanaka, Y | 1 |
| Argenzio, RA; Berschneider, HM; Chen, W; Chu, P; Paradiso, AM; Rhoads, JM | 1 |
| Abadie, A; Amirand, C; Dugas, B; Kolb, JP; Tran, PL | 1 |
| Delamere, NA; Mito, T | 1 |
| Ishikawa, Y; Ogawa, A; Sasakawa, S | 1 |
| Cortijo, J; De Diego, A; Esplugues, J; Morcillo, EJ; Perpiñá, M; Villagrasa, V | 1 |
| Chalfant, ML; Civan, JM; Civan, MM; DiBona, DR; O'Brien, TG; Peterson-Yantorno, K | 1 |
| Chander, A; Spitzer, A; Wadsworth, S; Wu, AM | 1 |
| Frindt, G; Palmer, LG; Windhager, EE | 1 |
| Aiuchi, T; Masuda, Y; Nakajo, S; Nakaya, K; Ohizumi, H; Watabe, M; Yoda, M | 1 |
| Reinach, PS; Torres-zamorano, V; Wu, X; Yang, H | 1 |
| Cheng, CP; Little, WC; Ohte, N; Suzuki, M; Wang, ZM; Williams, DL | 1 |
| Ito, Y; Marunaka, Y; Niisato, N | 1 |
| Hibell, AD; Humphrey, PP; Michel, AD; Thompson, KM; Xing, M | 1 |
| Beil, M; Danhof, M; Fu, F; Luttringer, O; Ploeger, BA; Rigel, DF; Snelder, N; Stanski, DR | 1 |
41 other study(ies) available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and amiloride
| Article | Year |
|---|---|
Decreased insulin-sensitive Ca2+ transport in cultured vascular smooth muscle cells from spontaneously hypertensive rats.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Animals; Biological Transport; Calcium; Calcium Channel Blockers; Calcium Radioisotopes; Cells, Cultured; Diltiazem; Gallic Acid; Homeostasis; Hypertension; Insulin; Isoquinolines; Male; Muscle, Smooth, Vascular; Piperazines; Protein Kinase C; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1992 |
Role of protein kinase C and the Na+/H+ antiporter in suppression of apoptosis by granulocyte macrophage colony-stimulating factor and interleukin-3.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Amiloride; Carrier Proteins; Cell Death; Clone Cells; DNA, Neoplasm; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-3; Isoquinolines; Kinetics; Leukemia, Megakaryoblastic, Acute; Piperazines; Protein Kinase C; Receptors, Granulocyte-Macrophage Colony-Stimulating Factor; Receptors, Interleukin-3; Recombinant Proteins; Sodium-Hydrogen Exchangers; Staurosporine; Tetradecanoylphorbol Acetate | 1992 |
Stimulatory effect of vanadate on 3',5'-cyclic guanosine monophosphate-inhibited low Michaelis-Menten constant 3',5'-cyclic adenosine monophosphate phosphodiesterase activity in isolated rat fat pads.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3',5'-Cyclic-AMP Phosphodiesterases; Adipose Tissue; Alkaloids; Amiloride; Animals; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Activation; Insulin; Isoquinolines; Kinetics; Male; Microsomes; Piperazines; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Inbred Strains; Receptor, Insulin; Staurosporine; Vanadates | 1992 |
Calcium and potassium channel regulation by protein phosphorylation in smooth muscle cells of guinea pig taenia coli.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Animals; Atropine; Calcium Channels; Carbachol; Colon; Guinea Pigs; In Vitro Techniques; Isoquinolines; Marine Toxins; Membrane Potentials; Models, Biological; Muscle, Smooth; Nifedipine; Oxazoles; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphorylation; Piperazines; Potassium Channels; Protein Kinase C | 1992 |
Mechanism of sodium transport inhibition by epidermal growth factor in cortical collecting ducts.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Animals; Biological Transport, Active; Calcium; Carrier Proteins; Desoxycorticosterone; Epidermal Growth Factor; Indomethacin; Isoquinolines; Kidney Cortex; Kidney Tubules, Collecting; Kinetics; Pertussis Toxin; Piperazines; Protein Kinase C; Rabbits; Reference Values; Sodium; Sodium-Hydrogen Exchangers; Virulence Factors, Bordetella | 1991 |
Protein kinase C stimulation enhances the process formation of adult oligodendrocytes and induces proliferation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Animals; Brain; Cell Division; Cells, Cultured; Glial Fibrillary Acidic Protein; Isoquinolines; Microscopy, Electron; Microscopy, Electron, Scanning; Nerve Regeneration; Oligodendroglia; Piperazines; Protein Kinase C; Swine; Tetradecanoylphorbol Acetate | 1991 |
Effects of pH on phosphate transport by flounder renal tubule primary cultures.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Absorption; Amiloride; Animals; Biological Transport; Cells, Cultured; Flounder; Hydrogen-Ion Concentration; Isoquinolines; Kidney Tubules; Kinetics; Phorbol Esters; Phosphates; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Sodium-Potassium-Exchanging ATPase; Type C Phospholipases | 1991 |
Exogeneous diacylglycerols downregulate the activity of Na(+)-K+ pump in Xenopus laevis oocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Animals; Biological Transport, Active; Cell Membrane; Diglycerides; Female; In Vitro Techniques; Isoquinolines; Kinetics; Oocytes; Piperazines; Protein Kinase C; Rubidium; Sodium; Sodium-Potassium-Exchanging ATPase; Tetradecanoylphorbol Acetate; Xenopus laevis | 1991 |
Alpha 1-adrenoceptor stimulation increases intracellular pH and Ca2+ in cardiomyocytes through Na+/H+ and Na+/Ca2+ exchange.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adrenergic alpha-Agonists; Amiloride; Animals; Calcium; Fluorescent Dyes; Heart; Hydrogen; Hydrogen-Ion Concentration; Ion Exchange; Isoquinolines; Male; Myocardium; Norepinephrine; Phentolamine; Piperazines; Prazosin; Propranolol; Protein Kinase Inhibitors; Rats; Rats, Inbred Strains; Sodium; Yohimbine | 1990 |
WS-1 human fibroblasts contain distinct calcium and protein kinase C-mediated pathways for activation of Na+/H+ exchange: contrasting effects of thrombin and PMA.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Amiloride; Biological Transport; Calcium; Cells, Cultured; DNA Replication; Enzyme Activation; Fibroblasts; Humans; Hydrogen; Hydrogen-Ion Concentration; Isoquinolines; Piperazines; Protein Kinase C; Sodium; Staurosporine; Tetradecanoylphorbol Acetate; Thrombin | 1991 |
Phorbol ester treatment stimulates tyrosine phosphorylation of a sea urchin egg cortex protein.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Ammonium Chloride; Animals; Carrier Proteins; Egg Proteins; Female; Hydrogen-Ion Concentration; Isoquinolines; Molecular Weight; Ovum; Phosphoproteins; Phosphorylation; Piperazines; Protein Kinase C; Sea Urchins; Signal Transduction; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate; Tyrosine | 1990 |
Effects of inhibitors of protein kinase C and Na+/H+ exchange on alpha 1-adrenoceptor-mediated inotropic responses in the rat left ventricular papillary muscle.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Amiloride; Animals; Heart Ventricles; Hydrogen; In Vitro Techniques; Ion Exchange; Isoquinolines; Male; Myocardial Contraction; Papillary Muscles; Piperazines; Prazosin; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Sodium; Staurosporine | 1990 |
Endothelin stimulates Na+/H+ exchange in vascular smooth muscle cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Animals; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Endothelins; Hydrogen; Hydrogen-Ion Concentration; Ion Exchange; Isoquinolines; Muscle, Smooth, Vascular; Nicardipine; Peptides; Piperazines; Protein Kinase C; Sodium | 1990 |
Vasoactive intestinal peptide stimulates active K+ transport and Na(+)-K(+)-Cl- cotransport in HT-29 cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenocarcinoma; Amiloride; Biological Transport; Bumetanide; Carrier Proteins; Cell Line; Chlorides; Colonic Neoplasms; Humans; Isoquinolines; Kinetics; Norepinephrine; Ouabain; Piperazines; Potassium; Protein Kinase C; Sodium-Potassium-Chloride Symporters; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vasoactive Intestinal Peptide; Yohimbine | 1990 |
Inhibition by amiloride and by Na+-depletion of A23187-stimulated arachidonic acid and histamine release from rat mast cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Carrier Proteins; Histamine Release; In Vitro Techniques; Isoquinolines; Mast Cells; Piperazines; Protein Kinase C; Rats; Sodium; Sodium-Hydrogen Exchangers; Sphingosine | 1988 |
[Mechanisms of thrombin-induced plasminogen activator release].
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Animals; Cyclic AMP; Isoquinolines; Milrinone; Phosphatidylinositols; Phosphodiesterase Inhibitors; Piperazines; Protein Kinase C; Pyridazines; Pyridones; Secretory Rate; Swine; Thrombin; Tissue Plasminogen Activator | 1989 |
Leukotriene D4-induced proliferation of glomerular epithelial cells: PKC- and Na+-H+ exchanger-mediated response.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Carrier Proteins; Cell Division; Cells, Cultured; DNA Replication; Epithelial Cells; Epithelium; Humans; Isoquinolines; Kidney Glomerulus; Kinetics; Piperazines; Protein Kinase C; Sodium-Hydrogen Exchangers; SRS-A; Thymidine | 1989 |
Studies on the mechanism by which prolactin regulates protein, RNA, and DNA synthesis in Nb2 node lymphoma cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Carrier Proteins; Cell Division; DNA, Neoplasm; Isoquinolines; Lymphoma; Neoplasm Proteins; Piperazines; Prolactin; Protein Kinase Inhibitors; Protein Kinases; RNA, Neoplasm; Sodium-Hydrogen Exchangers; Time Factors; Tumor Cells, Cultured | 1989 |
A role for protein kinase C in the membrane fusion necessary for platelet granule secretion.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Blood Platelets; Calcimycin; Carrier Proteins; Cytoplasmic Granules; Diglycerides; Humans; In Vitro Techniques; Isoquinolines; Membrane Fusion; Membrane Potentials; Phosphoproteins; Piperazines; Platelet Aggregation; Protein Kinase C; Sodium-Hydrogen Exchangers; Sphingosine; Tetradecanoylphorbol Acetate | 1989 |
The role of protein kinase-C in sensitization and antigen response of airway smooth muscle.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Animals; Antibody Specificity; Antigens; Carbazoles; Guinea Pigs; Histamine; Immunization; Immunoglobulin G; Indoles; Indomethacin; Isoquinolines; Male; Membrane Potentials; Muscle Contraction; Muscle, Smooth; Ovalbumin; Piperazines; Potassium Chloride; Protein Kinase C; Tetradecanoylphorbol Acetate; Trachea | 1989 |
Cytoplasmic pH change induced by leukotriene B4 in human neutrophils.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetamides; Amiloride; Carrier Proteins; Chemotaxis, Leukocyte; Cytoplasm; Dose-Response Relationship, Drug; GTP-Binding Proteins; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Isoquinolines; Leukotriene B4; Neutrophils; Pertussis Toxin; Piperazines; Protein Kinase C; Sodium-Hydrogen Exchangers; Time Factors; Virulence Factors, Bordetella | 1988 |
Inhibition of proto-oncogene c-fos transcription by inhibitors of protein kinase C and ion transport.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 4-Aminopyridine; Amiloride; Aminopyridines; Biological Transport, Active; Calcimycin; Humans; Isoquinolines; Phorbol Esters; Piperazines; Potassium; Protein Kinase C; Proto-Oncogene Mas; Proto-Oncogenes; Quinidine; RNA, Messenger; Sodium; Tetraethylammonium Compounds; Transcription, Genetic | 1987 |
Mechanisms of dopamine effects on Na-K-ATPase activity in Madin-Darby canine kidney (MDCK) epithelial cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 3',5'-Cyclic-AMP Phosphodiesterases; Amiloride; Animals; Cell Line; Cyclic AMP-Dependent Protein Kinases; Dideoxyadenosine; Dogs; Domperidone; Dopamine; Dopamine D2 Receptor Antagonists; Epithelium; Ergolines; Furosemide; Isoquinolines; Kidney; Kidney Tubules, Collecting; Piperazines; Protein Kinase C; Quinpirole; Receptors, Dopamine D1; Sodium-Potassium-Exchanging ATPase | 1995 |
Activation of Na+/H+ exchanger by hepatocyte growth factor in hepatocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Animals; Cells, Cultured; Genistein; Hepatocyte Growth Factor; Hydrogen-Ion Concentration; Isoflavones; Isoquinolines; Liver; Male; Piperazines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Signal Transduction; Sodium-Hydrogen Exchangers; Sulfonamides | 1995 |
Intracellular alkalinization suppresses lovastatin-induced apoptosis in HL-60 cells through the inactivation of a pH-dependent endonuclease.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Apoptosis; Cell Cycle; Cell Line; Cycloheximide; DNA, Neoplasm; Endodeoxyribonucleases; Fluoresceins; Fluorescent Dyes; Humans; Hydrogen-Ion Concentration; Isoquinolines; Kinetics; Leukemia, Promyelocytic, Acute; Lovastatin; Mevalonic Acid; Piperazines; Protein Kinase C; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured | 1995 |
Characterization of signaling pathways to Na+/H+ exchanger activation with epidermal growth factor in hepatocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Animals; Calcium; Calcium-Transporting ATPases; Calmodulin; Cells, Cultured; Epidermal Growth Factor; Genistein; Hydrogen-Ion Concentration; Isoflavones; Isoquinolines; Liver; Male; Phenylephrine; Piperazines; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Signal Transduction; Sodium-Hydrogen Exchangers; Sulfonamides; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1994 |
L-glutamine and L-asparagine stimulate Na+ -H+ exchange in porcine jejunal enterocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acid-Base Equilibrium; Amiloride; Ammonium Chloride; Animals; Asparagine; Cell Line; Epithelium; Fluoresceins; Fluorescent Dyes; Glutamine; Hydrogen-Ion Concentration; Isoquinolines; Jejunum; Kinetics; Mannitol; Meglumine; Piperazines; Protein Kinase C; Sodium; Sodium-Hydrogen Exchangers; Swine; Tetradecanoylphorbol Acetate; Time Factors | 1994 |
Inhibitory effect of staurosporine on protein kinase C stimulation of airway smooth muscle cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Action Potentials; Alkaloids; Amiloride; Animals; Carbazoles; Dose-Response Relationship, Drug; Furosemide; Guinea Pigs; Indoles; Isometric Contraction; Isoquinolines; Male; Membrane Potentials; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Ovalbumin; Piperazines; Protein Kinase C; Respiratory Muscles; Staurosporine; Tetradecanoylphorbol Acetate; Trachea | 1993 |
Intracellular signaling events associated with the induction of DNA synthesis in human B lymphocytes. I. Stimulation of PKC-dependent and -independent pathways by LMW-BCGF.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Amiloride; B-Lymphocytes; Carrier Proteins; DNA; Enzyme Activation; Humans; Hydrogen-Ion Concentration; Isoquinolines; Lymphokines; Mitosis; Neomycin; Piperazines; Protein Kinase C; Signal Transduction; Sodium-Hydrogen Exchangers; Staurosporine; Type C Phospholipases | 1993 |
Alteration of active Na-K transport on protein kinase C activation in cultured ciliary epithelium.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Biological Transport, Active; Carrier Proteins; Cell Transformation, Viral; Cells, Cultured; Ciliary Body; Enzyme Activation; Humans; Isoquinolines; Ouabain; Phorbol 12,13-Dibutyrate; Pigment Epithelium of Eye; Piperazines; Potassium; Protein Kinase C; Rubidium Radioisotopes; Sodium; Sodium-Hydrogen Exchangers; Sodium-Potassium-Exchanging ATPase | 1993 |
Na+/H+ exchange activity induced by thrombin is not inhibited by protein kinase inhibitors, staurosporine, K-252a, H-7 and sphingosine, in human platelets.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Amiloride; Blood Platelets; Carbazoles; Carrier Proteins; Humans; Hydrogen; Indole Alkaloids; Isoquinolines; Phosphorylation; Piperazines; Protein Kinase C; Protein Processing, Post-Translational; Sodium; Sodium-Hydrogen Exchangers; Sphingosine; Staurosporine; Thrombin | 1993 |
Effects of phorbol 12,13-diacetate and its influence on spasmogenic responses in normal and sensitized guinea-pig trachea.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Animals; Calcium; Diuretics; Guinea Pigs; Histamine; In Vitro Techniques; Indomethacin; Isoquinolines; Male; Muscle Contraction; Muscle, Smooth; Phorbol Esters; Piperazines; Potassium Chloride; Protein Kinase C; Serotonin; Trachea; Vasodilator Agents; Verapamil | 1995 |
Regulation of epithelial Na+ permeability by protein kinase C is tissue specific.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Aldosterone; Alkaloids; Amiloride; Animals; Benzophenanthridines; Biological Transport; Bufo marinus; Enzyme Inhibitors; Epithelium; In Vitro Techniques; Isoquinolines; Kinetics; Membrane Potentials; Organ Specificity; Phenanthridines; Piperazines; Protein Kinase C; Rana catesbeiana; Rana pipiens; Skin; Skin Physiological Phenomena; Sodium; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors; Urinary Bladder | 1996 |
Protein kinase C in intracellular pH regulation in alveolar type II cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acids; Amiloride; Animals; Bicarbonates; Buffers; Extracellular Space; Hydrogen-Ion Concentration; Intracellular Membranes; Male; Protein Kinase C; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Sodium; Tetradecanoylphorbol Acetate | 1996 |
Feedback regulation of Na channels in rat CCT. IV. Mediation by activation of protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Down-Regulation; Enzyme Activation; Feedback; Female; Kidney Tubules, Collecting; Male; Ouabain; Patch-Clamp Techniques; Phorbols; Protein Kinase C; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Sodium Channels; Staurosporine; Tetradecanoylphorbol Acetate; Up-Regulation | 1996 |
Activation of protein kinase C prevents induction of apoptosis by geranylgeraniol in human leukemia HL60 cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Animals; Apoptosis; Diglycerides; Diterpenes; Enzyme Activation; Enzyme Inhibitors; HL-60 Cells; Humans; Leukemia; Mice; Neoplasm Proteins; Phorbol Esters; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1997 |
ETA receptor mediated inhibition of intracellular pH regulation in cultured bovine corneal epithelial cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Animals; Arsenicals; Calcium-Calmodulin-Dependent Protein Kinases; Cattle; Cells, Cultured; Chelating Agents; Cyclosporine; Diuretics; Egtazic Acid; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Epithelium, Corneal; Hydrogen-Ion Concentration; Immunosuppressive Agents; Intracellular Fluid; Naphthalenes; Okadaic Acid; Peptides, Cyclic; Phosphoprotein Phosphatases; Protein Kinase C; Receptors, Endothelin; Spectrometry, Fluorescence; Tetradecanoylphorbol Acetate | 1998 |
Altered inotropic response of endothelin-1 in cardiomyocytes from rats with isoproterenol-induced cardiomyopathy.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Animals; Anti-Arrhythmia Agents; Calcium; Cardiotonic Agents; Cell Size; Cells, Cultured; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Heart Failure; Hemodynamics; Isoproterenol; Male; Myocardial Contraction; Myocardium; Peptides, Cyclic; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptors, Endothelin; Sodium-Hydrogen Exchangers; Staurosporine | 1998 |
Effects of PKA inhibitors, H-compounds, on epithelial Na+ channels via PKA-independent mechanisms.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Animals; Carbazoles; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epithelial Cells; Indoles; Isoquinolines; Myristic Acid; Pulmonary Alveoli; Pyrroles; Rats; Rats, Wistar; Sodium; Sodium Channels; Structure-Activity Relationship; Sulfonamides; Terbutaline | 1999 |
Complexities of measuring antagonist potency at P2X(7) receptor orthologs.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Amiloride; Animals; Benzoxazoles; Buffers; Cations, Divalent; Cell Adhesion; Cells, Cultured; Drug Interactions; Enzyme Inhibitors; Ethidium; Fluorescent Dyes; Humans; Kinetics; Mice; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Quinolinium Compounds; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Rosaniline Dyes; Serum Albumin, Bovine; Sodium Chloride; Species Specificity; Temperature | 2001 |
Drug effects on the CVS in conscious rats: separating cardiac output into heart rate and stroke volume using PKPD modelling.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Amlodipine; Animals; Atropine; Enalapril; Hemodynamics; Hydrochlorothiazide; Hypertension; Male; Models, Biological; Prazosin; Propranolol; Rats, Inbred SHR; Rats, Inbred WKY | 2014 |