1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with adenosine in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (19.23) | 18.7374 |
| 1990's | 15 (57.69) | 18.2507 |
| 2000's | 6 (23.08) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Amatsu, M; Nishimura, S; Okada, Y | 1 |
| Hasegawa, S; Luo, JJ | 1 |
| Asano, K; Iizuka, H; Ito, F; Takahashi, H; Tamura, T; Tsutsui, M | 1 |
| Casillas, T; Delicado, EG; Miras-Portugal, MT; Sen, RP | 1 |
| Ribeiro, JA; Sebastião, AM | 1 |
| Hirsh, JK; Silinsky, EM; Solsona, CS | 1 |
| Smalheiser, NR | 1 |
| Brailoiu, E; Brănişteanu, DD; Covic, A; Haulica, ID; Serban, DN | 1 |
| Murayama, T; Nomura, Y; Ui, M | 1 |
| Chen, H; Dryden, WF; Singh, YN | 1 |
| Kizaki, H; Ohsaka, F; Sakurada, T; Shimada, H | 1 |
| Hidaka, H; Ohta, H; Tanaka, T | 1 |
| Doris, R; Houslay, MD; Kilgour, E; Thompson, GE; Vernon, RG | 1 |
| Hirai, H; Ikeuchi, Y; Okada, Y | 1 |
| Hirai, H; Okada, Y | 1 |
| Gobran, LI; Griese, M; Rooney, SA | 1 |
| Harada, H; Motomura, A; Suketa, Y; Suzuki, S; Tai, H | 1 |
| Hashimoto, Y; Iizuka, H; Ishida-Yamamoto, A; Takahashi, H | 1 |
| Gubitz, AK; Kirkpatrick, KA; Kurokawa, M; Richardson, PJ; Widdowson, L | 1 |
| Dobson, JG; Ethier, MF | 1 |
| Oriji, GK | 1 |
| Conigrave, AD; Fernando, KC; Gu, B; Luttrell, BM; Tasevski, V; Wiley, JS; Zhang, W | 1 |
| Etgen, AM; Fiber, JM | 1 |
| Frerking, M; Partovi, D | 1 |
| Gao, C; Gao, N; Hu, HZ; Liu, S; Wood, JD; Xia, Y | 1 |
| Gok, S; Izanli-Paksoy, A; Vural, K | 1 |
26 other study(ies) available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and adenosine
| Article | Year |
|---|---|
Post-inhibitory excitation of adenosine on neurotransmission in guinea pig hippocampal slices.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenine Nucleotides; Adenosine; Animals; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Isoquinolines; Pentobarbital; Piperazines; Protein Kinase C; Synaptic Transmission | 1992 |
Chick sympathetic neurons in culture respond differentially to nerve growth factor and conditioned medium from activated splenic lymphocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine; Animals; Cell Survival; Cells, Cultured; Chickens; Culture Media; Deoxyadenosines; Ganglia, Sympathetic; Isoquinolines; Kinetics; Lymphocyte Activation; Lymphocytes; Nerve Growth Factors; Neurons; Piperazines; Proadifen; Protein Kinase Inhibitors; Spleen; Thioguanine; Thionucleosides | 1991 |
Desensitization of the epidermal adenylate cyclase system: agonists and phorbol esters desensitize by independent mechanisms.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine; Adenosine Triphosphate; Adenylate Cyclase Toxin; Adenylyl Cyclases; Alkaloids; Animals; Cholera Toxin; Colforsin; Cyclic AMP; Epidermis; Epinephrine; Histamine; Isoquinolines; Pertussis Toxin; Piperazines; Receptors, Adrenergic, beta; Receptors, Histamine; Skin; Staurosporine; Swine; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1991 |
Control of nucleoside transport in neural cells. Effect of protein kinase C activation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine; Adrenal Medulla; Animals; Biological Transport; Calcimycin; Caprylates; Cells, Cultured; Diglycerides; Dinucleoside Phosphates; Enzyme Activation; Ethers, Cyclic; Isoquinolines; Kinetics; Okadaic Acid; Phorbol 12,13-Dibutyrate; Piperazines; Protein Kinase C; Tetradecanoylphorbol Acetate; Triglycerides | 1991 |
Interactions between adenosine and phorbol esters or lithium at the frog neuromuscular junction.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine; Adenylyl Cyclases; Animals; Colforsin; Enzyme Activation; Evoked Potentials; Imines; Isoquinolines; Lithium; Muscles; Neuromuscular Junction; Phorbol Esters; Piperazines; Polymyxin B; Protein Kinase C; Rana ridibunda; Synaptic Transmission | 1990 |
The role of cyclic AMP and its protein kinase in mediating acetylcholine release and the action of adenosine at frog motor nerve endings.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetylcholine; Adenosine; Animals; Cyclic AMP; In Vitro Techniques; Isoquinolines; Liposomes; Motor Endplate; Phosphorylation; Piperazines; Protein Kinase Inhibitors; Protein Kinases; Rana pipiens; Receptors, Purinergic | 1990 |
Cell attachment and neurite stability in NG108-15 cells: effects of 5'-deoxy, 5'-methyl thioadenosine (MTA) compared with laminin, kinase inhibitor H-7, and Mn2+ ions.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine; Animals; Cell Adhesion; Cells, Cultured; Dendrites; Deoxyadenosines; Isoquinolines; Laminin; Manganese; Nerve Growth Factors; Neurons; Piperazines; Thionucleosides | 1990 |
Adenosine effects upon the spontaneous quantal transmitter release at the frog neuromuscular junction in the presence of protein kinase C-blocking and -activating agents.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetylcholine; Adenosine; Animals; Diglycerides; Glycerides; In Vitro Techniques; Isoquinolines; Neuromuscular Junction; Piperazines; Polymyxin B; Polymyxins; Protease Inhibitors; Protein Kinase C; Rana ridibunda | 1989 |
Enhancement of adenosine A2 and prostaglandin E1 receptor-mediated cAMP generation by prior exposure of Swiss 3T3 fibroblasts to Ca2+-mobilizing receptor agonists or phorbol ester. Activation of protein kinase C triggers increases in the receptor density
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine; Adenylyl Cyclases; Alkaloids; Animals; Calcium; Cell Membrane; Cells, Cultured; Cyclic AMP; Diglycerides; Enzyme Activation; Fibroblasts; Isoquinolines; Kinetics; Mice; Piperazines; Prostaglandins E; Protein Kinase C; Receptors, Prostaglandin; Receptors, Prostaglandin E; Receptors, Purinergic; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate | 1989 |
Transduction mechanism involving the presynaptic adenosine receptor at mouse motor nerve terminals.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 2-Chloroadenosine; Adenosine; Animals; Enzyme Inhibitors; Isoquinolines; Membrane Potentials; Mice; Motor Endplate; Motor Neurons; Neuromuscular Junction; Pertussis Toxin; Piperazines; Protein Kinases; Receptors, Purinergic; Signal Transduction; Virulence Factors, Bordetella | 1989 |
Adenosine, deoxyadenosine, and deoxyguanosine induce DNA cleavage in mouse thymocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine; Animals; Calcium; Cycloheximide; Deoxyadenosines; Deoxyguanosine; DNA; DNA Damage; Isoquinolines; Kinetics; L-Lactate Dehydrogenase; Male; Mice; Mice, Inbred BALB C; Piperazines; Poly Adenosine Diphosphate Ribose; Purine Nucleosides; T-Lymphocytes; Zinc | 1988 |
Putative binding site(s) of 1-(5-isoquinolinesulfonyl)-2-methylpiperazine (H-7) on protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine; Animals; Binding Sites; Dithionitrobenzoic Acid; Isoquinolines; Piperazines; Protein Binding; Protein Kinase C; Rabbits | 1988 |
Modulation of adenosine signalling in sheep adipose tissue by growth hormone.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine; Adipose Tissue; Animals; Cattle; Cells, Cultured; Ethers, Cyclic; Growth Hormone; Isoproterenol; Isoquinolines; Kinetics; Lipolysis; Okadaic Acid; Phenylisopropyladenosine; Phosphoprotein Phosphatases; Piperazines; Protein Kinase C; Recombinant Proteins; Sheep; Signal Transduction | 1995 |
The contribution of PKA to the excitatory mechanism of adenosine in guinea pig superior colliculus slices.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine; Animals; Bucladesine; Culture Media; Cyclic AMP-Dependent Protein Kinases; Guinea Pigs; In Vitro Techniques; Isoquinolines; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Sulfonamides; Superior Colliculi; Synaptic Transmission | 1994 |
Adenosine facilitates glutamate release in a protein kinase-dependent manner in superior colliculus slices.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine; Animals; Calcium; Electric Stimulation; Electrophysiology; Glutamates; Glutamic Acid; Guinea Pigs; In Vitro Techniques; Isoquinolines; Piperazines; Protein Kinase Inhibitors; Protein Kinases; Sulfonamides; Superior Colliculi; Tetrodotoxin | 1994 |
Signal-transduction mechanisms of ATP-stimulated phosphatidylcholine secretion in rat type II pneumocytes: interactions between ATP and other surfactant secretagogues.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Cells, Cultured; Drug Interactions; Ionomycin; Isoquinolines; L-Lactate Dehydrogenase; Lung; Male; Phosphatidylcholines; Piperazines; Rats; Rats, Sprague-Dawley; Signal Transduction; Sulfonamides; Terbutaline; Tetradecanoylphorbol Acetate; Xanthines | 1993 |
Extracellular ATP-induced regulation of epidermal growth factor signaling in cultured renal LLC-PK1 cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine; Adenosine Triphosphate; Animals; Cell Line; Cell Membrane; Cytosol; Epidermal Growth Factor; ErbB Receptors; Inositol 1,4,5-Trisphosphate; Isoquinolines; Kidney; Kinetics; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Rabbits; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate | 1993 |
Activators of protein kinase C but not of phospholipase C modulate adenylate cyclase-responses of normal pig epidermis.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine; Adenylyl Cyclases; Animals; Bradykinin; Cell Division; Cholera Toxin; Colforsin; Cyclic AMP; Diglycerides; Dinoprostone; Enzyme Activation; Enzyme Inhibitors; Epidermal Cells; Epidermal Growth Factor; Epidermis; Epinephrine; Histamine; Isoquinolines; Keratinocytes; Piperazines; Protein Kinase C; Swine; Tetradecanoylphorbol Acetate; Thrombin; Type C Phospholipases | 1995 |
Dual signalling by the adenosine A2a receptor involves activation of both N- and P-type calcium channels by different G proteins and protein kinases in the same striatal nerve terminals.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholine; Adenosine; Agatoxins; Alkaloids; Animals; Antihypertensive Agents; Benzophenanthridines; Calcium Channel Blockers; Calcium Channels; Cholera Toxin; Cholinergic Fibers; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; GTP-Binding Proteins; Isoquinolines; Neostriatum; Neurons; Phenanthridines; Phenethylamines; Piperazines; Potassium; Presynaptic Terminals; Protein Kinase C; Protein Kinases; Rats; Rats, Wistar; Receptors, Purinergic P1; Signal Transduction; Spider Venoms; Stereoisomerism; Sulfonamides; Tritium; Xanthines | 1996 |
Adenosine stimulation of DNA synthesis in human endothelial cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Triphosphate; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DNA; Endothelium, Vascular; Humans; Kinetics; Poly A; Purinergic P1 Receptor Antagonists; Quinazolines; Tetradecanoylphorbol Acetate; Thioinosine; Thionucleotides; Thymidine; Triazoles; Umbilical Veins | 1997 |
Adenosine induced direct negative inotropic effect is abolished during global ischemia: role of protein kinase C and prostacyclin.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine; Animals; Depression, Chemical; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Epoprostenol; Heart Rate; Indomethacin; Male; Myocardial Contraction; Myocardial Ischemia; Perfusion; Phorbol 12,13-Dibutyrate; Prostaglandin Antagonists; Protein Kinase C; Rats; Vasodilator Agents | 2000 |
P2Y(11) receptor expression by human lymphocytes: evidence for two cAMP-linked purinoceptors.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Cyclic AMP; Dose-Response Relationship, Drug; Gene Expression; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocytes; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2X7; RNA, Messenger | 2001 |
Modulation of GABA-augmented norepinephrine release in female rat brain slices by opioids and adenosine.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine; Animals; Brain; Electric Stimulation; Enzyme Inhibitors; Female; Frontal Lobe; gamma-Aminobutyric Acid; Hypothalamus; In Vitro Techniques; Narcotics; Norepinephrine; Parietal Lobe; Rats; Rats, Sprague-Dawley | 2001 |
Presynaptic inhibition by kainate receptors converges mechanistically with presynaptic inhibition by adenosine and GABAB receptors.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine; Alanine; Animals; Baclofen; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; GABA Agonists; Glutamic Acid; In Vitro Techniques; Kainic Acid; Male; Naphthalenes; Neuromuscular Depolarizing Agents; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Receptors, Kainic Acid; Receptors, Presynaptic; Thymine | 2006 |
Stimulation of adenosine A1 and A2A receptors by AMP in the submucosal plexus of guinea pig small intestine.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Action Potentials; Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Boron Compounds; Enzyme Inhibitors; Estrenes; Excitatory Postsynaptic Potentials; Guinea Pigs; Ileum; Indoles; Male; Maleimides; Norepinephrine; Phenethylamines; Pyrrolidinones; Quinazolines; Receptor, Adenosine A1; Receptor, Adenosine A2A; Signal Transduction; Submucous Plexus; Synaptic Transmission; Tetrodotoxin; Theophylline; Triazines; Triazoles | 2007 |
Contribution of RhoA kinase and protein kinase C to weak relaxant effect of pinacidil on carbachol-induced contractions in sensitized guinea-pig trachealis.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine; Animals; Benzophenanthridines; Bronchodilator Agents; Carbachol; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; KATP Channels; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Ovalbumin; Pinacidil; Protein Kinase C; rhoA GTP-Binding Protein; Trachea | 2009 |