1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with 4-aminopyridine in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (6.67) | 18.7374 |
| 1990's | 4 (26.67) | 18.2507 |
| 2000's | 5 (33.33) | 29.6817 |
| 2010's | 5 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Barnett, NL; Broyden, NJ; Morris, NJ; Osborne, NN | 1 |
| Kuroki, T; Nose, K; Shibanuma, M | 1 |
| Chaki, S; Muramatsu, M; Otomo, S | 1 |
| Grillner, S; Parker, D; Svensson, E | 1 |
| Himmelreich, NH; Pozdnyakova, NG; Storchak, LG | 1 |
| Blandizzi, C; Colucci, R; Del Tacca, M; Tognetti, M | 1 |
| Henne, J; Jeserich, G; Panofen, F; Rabe, H | 1 |
| Anderson, A; Beck, H; Becker, A; Bernard, C; Johnston, D; Poolos, NP | 1 |
| Jiang, L; Kang, J; Kang, N; Nedergaard, M; Xu, J | 1 |
| Hou, X; Wang, X; Yang, B; Yu, G; Zhang, L; Zhou, J | 1 |
| Draheim, HJ; Lamodière, E; Moussaud, S; Savage, C | 1 |
| Balezina, OP; Bogatcheva, PO; Ezhova, EV | 1 |
| Bieger, D; Ford, CA; Tabrizchi, R | 1 |
| Adachi, M; Liu, Z; Wang, W; Xiao, J; Zhou, J | 1 |
15 other study(ies) available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and 4-aminopyridine
| Article | Year |
|---|---|
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Protein kinase C (alpha and beta) immunoreactivity in rabbit and rat retina: effect of phorbol esters and transmitter agonists on immunoreactivity and the translocation of the enzyme from cytosolic to membrane compartments.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 4-Aminopyridine; Aging; Alkaloids; Animals; Antibodies, Monoclonal; Cell Membrane; Cytosol; Fluorescent Antibody Technique; In Vitro Techniques; Isoenzymes; Isoquinolines; Kinetics; Phorbol Esters; Piperazines; Protein Kinase C; Quisqualic Acid; Rabbits; Rats; Retina; Sphingosine; Staurosporine | 1991 |
Inhibition of proto-oncogene c-fos transcription by inhibitors of protein kinase C and ion transport.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 4-Aminopyridine; Amiloride; Aminopyridines; Biological Transport, Active; Calcimycin; Humans; Isoquinolines; Phorbol Esters; Piperazines; Potassium; Protein Kinase C; Proto-Oncogene Mas; Proto-Oncogenes; Quinidine; RNA, Messenger; Sodium; Tetraethylammonium Compounds; Transcription, Genetic | 1987 |
Involvement of protein kinase C activation in regulation of acetylcholine release from rat hippocampal slices by minaprine.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 4-Aminopyridine; Acetylcholine; Alkaloids; Animals; Enzyme Activation; Hippocampus; In Vitro Techniques; Isoquinolines; Male; Phorbol 12,13-Dibutyrate; Piperazines; Potassium; Protein Kinase C; Pyridazines; Rats; Rats, Wistar; Serotonin; Staurosporine; Synaptosomes; Tetradecanoylphorbol Acetate | 1994 |
Substance P modulates sensory action potentials in the lamprey via a protein kinase C-mediated reduction of a 4-aminopyridine-sensitive potassium conductance.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 4-Aminopyridine; Action Potentials; Adenylate Cyclase Toxin; Alkaloids; Animals; Benzophenanthridines; Cadmium Chloride; Electric Stimulation; Enzyme Inhibitors; Female; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; In Vitro Techniques; Intercellular Signaling Peptides and Proteins; Lampreys; Male; Neurons; Notochord; Peptides; Pertussis Toxin; Phenanthridines; Phorbol 12,13-Dibutyrate; Potassium Channels; Protein Kinase C; Protein Kinases; Spinal Cord; Substance P; Tetraethylammonium; Thionucleotides; Virulence Factors, Bordetella; Wasp Venoms | 1997 |
Differential effect of protein kinase inhibitors on calcium-dependent and calcium-independent [14C]GABA release from rat brain synaptosomes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 4-Aminopyridine; Animals; Biological Transport; Brain Chemistry; Calcium; Carbon Radioisotopes; Enzyme Inhibitors; gamma-Aminobutyric Acid; Male; Potassium Chloride; Rats; Sphingosine; Spider Venoms; Staurosporine; Sulfonamides; Synaptosomes | 1998 |
Histamine H(3) receptors mediate inhibition of noradrenaline release from intestinal sympathetic nerves.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 4-Aminopyridine; Adrenergic alpha-Antagonists; Animals; Calcium; Colforsin; Dose-Response Relationship, Drug; Ethylmaleimide; Guinea Pigs; Histamine; Histamine Agonists; Histamine Antagonists; Ileum; In Vitro Techniques; Intestinal Mucosa; Intestines; Male; Muscle, Smooth; Myenteric Plexus; Nifedipine; Norepinephrine; omega-Conotoxins; Pertussis Toxin; Phenols; Receptors, Histamine H3; Rolipram; Sympathetic Nervous System; Tetradecanoylphorbol Acetate; Tetraethylammonium; Tetrodotoxin; Virulence Factors, Bordetella; Yohimbine | 2000 |
Molecular cloning and functional characterization of Shaw-related potassium channels of trout CNS.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 4-Aminopyridine; Animals; Brain Chemistry; Carcinogens; Cloning, Molecular; DNA, Complementary; Electrophysiology; Enzyme Inhibitors; Gene Expression Regulation, Developmental; Membrane Potentials; Molecular Sequence Data; Muscle Relaxants, Central; Oncorhynchus mykiss; Potassium Channels; Potassium Channels, Voltage-Gated; Protein Kinase C; Quinine; Reverse Transcriptase Polymerase Chain Reaction; Sequence Homology, Amino Acid; Shaw Potassium Channels; Species Specificity; Tetradecanoylphorbol Acetate; Tetraethylammonium | 2000 |
Acquired dendritic channelopathy in temporal lobe epilepsy.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 4-Aminopyridine; Action Potentials; Animals; Butadienes; Dendrites; Enzyme Inhibitors; Epilepsy, Temporal Lobe; Hippocampus; Male; Membrane Potentials; Mitogen-Activated Protein Kinases; Nitriles; Phosphorylation; Pilocarpine; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Protein Kinase C; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Shal Potassium Channels | 2004 |
Activity-dependent long-term potentiation of intrinsic excitability in hippocampal CA1 pyramidal neurons.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 2-Amino-5-phosphonovalerate; 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Anisomycin; Bicuculline; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Egtazic Acid; Emetine; Excitatory Amino Acid Antagonists; Learning; Long-Term Potentiation; Patch-Clamp Techniques; Phosphinic Acids; Potassium Channels; Propanolamines; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sodium Channels | 2005 |
Rebound bursts in GABAergic neurons of the thalamic reticular nucleus in postnatal mice.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 4-Aminopyridine; Action Potentials; Animals; Animals, Newborn; Bicuculline; Calcium-Calmodulin-Dependent Protein Kinase Type 2; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Mice; Mice, Inbred ICR; Neural Inhibition; Neurons; Organ Culture Techniques; Potassium Channel Blockers; Protein Kinase Inhibitors; Receptors, GABA-A; Thalamic Nuclei | 2010 |
Characterisation of K+ currents in the C8-B4 microglial cell line and their regulation by microglia activating stimuli.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 4-Aminopyridine; Animals; Apamin; Barium; Calcium; Cations; Cell Line; Charybdotoxin; Dose-Response Relationship, Drug; Drug Combinations; Elapid Venoms; Electrodes; Electrophysiology; Fluorescent Antibody Technique, Direct; Genistein; Granulocyte-Macrophage Colony-Stimulating Factor; Interferon-gamma; Lipopolysaccharides; Membrane Potentials; Mice; Mice, Inbred C57BL; Microglia; Neurotoxins; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Inwardly Rectifying; Pyrazoles; Scorpion Venoms; Transforming Growth Factor beta | 2009 |
Mechanism of inhibition of acetylcholine secretion in newly formed mouse synapses involving Ca2+-dependent kinases and voltage-gated K+-channels.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 4-Aminopyridine; Acetylcholine; Animals; Benzophenanthridines; Calcium Channels, L-Type; Calcium-Calmodulin-Dependent Protein Kinases; Excitatory Postsynaptic Potentials; Imidazoles; Indoles; Maleimides; Mice; Muscle, Skeletal; Nifedipine; Potassium Channels, Voltage-Gated; Protein Kinase C; Synapses | 2010 |
Potassium-induced intermittent vasomotion in rat isolated pulmonary artery.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 4-Aminopyridine; Animals; Barium; Indoles; Male; Mibefradil; Nicardipine; Niflumic Acid; Potassium; Potassium Channels; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Tetraethylammonium; Verapamil | 2011 |
4-aminopyridine induces apoptosis of human acute myeloid leukemia cells via increasing [Ca2+]i through P2X7 receptor pathway.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 4-Aminopyridine; Apoptosis; Calcium; Calcium Channels; Caspase 3; Caspase 9; Humans; Leukemia, Myeloid, Acute; Membrane Potential, Mitochondrial; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Purinergic P2X Receptor Antagonists; Receptors, Purinergic P2X7; RNA Interference; RNA, Small Interfering; Tumor Cells, Cultured | 2011 |