Compounds > 1-(5-isoquinolinesulfonyl)-2-methylpiperazine

1-(5-isoquinolinesulfonyl)-2-methylpiperazine and 3'-o-(4-benzoyl)benzoyladenosine 5'-triphosphate

1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with 3'-o-(4-benzoyl)benzoyladenosine 5'-triphosphate in 21 studies

Research

Studies (21)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (9.52)	18.2507
2000's	14 (66.67)	29.6817
2010's	5 (23.81)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Blanchard, DK; Djeu, JY; Hoffman, SL	1
Cornish, JE; Gargett, CE; Wiley, JS	1
Chessell, IP; Humphrey, PP; Kaur, R; Michel, AD	1
Chiozzi, P; Di Virgilio, F; Dichmann, S; Ferrari, D; Idzko, M; Luttmann, W; Norgauer, J; Purlis, D; Virchow, C	1
Hibell, AD; Humphrey, PP; Michel, AD; Thompson, KM; Xing, M	1
Eschke, D; Hauschildt, S; Nieber, K; Wüst, M	1
Adinolfi, E; Baricordi, OR; Chiozzi, P; Di Virgilio, F; Morelli, A; Rizzo, R; Solini, A	1
Baraldi, PG; Di Virgilio, F; Romagnoli, R	1
Christopherson, RI; Fuller, SJ; Georgiou, JG; Martin, CJ; Skarratt, KK; Sluyter, R; Wiley, JS	1
Chimenti, D; Chiozzi, P; Cuccato, S; Di Virgilio, F; Falzoni, S; Ferrannini, E; Lupi, R; Pratesi, F; Pugliese, G; Santini, E; Solini, A	1
Dehaye, JP; Garcia-Marcos, M; Marino, A; Otto, A; Pochet, S; Seil, M	1
Hayato, R; Ohtubo, Y; Yoshii, K	1
Clay, WC; Condreay, JP; Fonfria, E; Goodwin, JA; Levy, DS; Michel, AD; Roman, S; Smith, GD	1
Chambers, LJ; Michel, AD; Walter, DS	1
Alberto, AP; Dahl, G; Iglesias, R; Locovei, S; Roque, A; Scemes, E; Spray, DC	1
An, D; Chen, J; He, B; Li, M; Liu, P; Meng, L; Zhang, X; Zhang, Y; Zhao, J	1
Bradley, HJ; Browne, LE; Jiang, LH; Yang, W	1
Chorvat, D; Lajdova, I; Oksa, A; Spustova, V; Topor, P	1
Chiarugi, M; Ferrannini, E; Madec, S; Rossi, C; Salvati, A; Santini, E; Solini, A	1
Bolognesi, G; Bozzato, D; Di Virgilio, F; Ferrari, D; Gulinelli, S; Idzko, M; Pizzirani, C; Salaro, E; Vuerich, M	1
Artalejo, AR; Bustillo, D; Marín-García, P; Miras-Portugal, MT; Olivos-Oré, LA; Sánchez-Nogueiro, J	1

Reviews

1 review(s) available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and 3'-o-(4-benzoyl)benzoyladenosine 5'-triphosphate

Article	Year
Agonists and antagonists acting at P2X7 receptor. Current topics in medicinal chemistry, 2004, Volume: 4, Issue:16 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Animals; Humans; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Structure-Activity Relationship	2004

Other Studies

20 other study(ies) available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and 3'-o-(4-benzoyl)benzoyladenosine 5'-triphosphate

Article	Year
Inhibition of extracellular ATP-mediated lysis of human macrophages by calmodulin antagonists. Journal of cellular biochemistry, 1995, Volume: 57, Issue:3 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Calcium; Calmodulin; Cell Death; Cells, Cultured; Cytosol; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interferon-gamma; Isoquinolines; Kinetics; Macrophages; Membrane Potentials; Piperazines	1995
ATP, a partial agonist for the P2Z receptor of human lymphocytes. British journal of pharmacology, 1997, Volume: 122, Issue:5 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Affinity Labels; Barium; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ethidium; Flow Cytometry; Humans; In Vitro Techniques; Ion Channels; Leukemia, Lymphocytic, Chronic, B-Cell; Linear Models; Lymphocytes; Purinergic P2 Receptor Agonists; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Structure-Activity Relationship; Thionucleotides	1997
Antagonist effects on human P2X(7) receptor-mediated cellular accumulation of YO-PRO-1. British journal of pharmacology, 2000, Volume: 130, Issue:3 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Antibodies, Blocking; Benzoxazoles; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Enzyme Inhibitors; Fluorescent Dyes; Humans; Imidazoles; In Vitro Techniques; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Quinolinium Compounds; Receptors, Purinergic P2X7; Stimulation, Chemical	2000
P2 purinergic receptors of human eosinophils: characterization and coupling to oxygen radical production. FEBS letters, 2000, Dec-15, Volume: 486, Issue:3 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Calcium; Chelating Agents; Complement C5a; Dose-Response Relationship, Drug; Enzyme Inhibitors; Eosinophils; Guanosine Triphosphate; Humans; Intracellular Fluid; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Reactive Oxygen Species; Receptors, Purinergic P2; Uridine Triphosphate	2000
Complexities of measuring antagonist potency at P2X(7) receptor orthologs. The Journal of pharmacology and experimental therapeutics, 2001, Volume: 296, Issue:3 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Amiloride; Animals; Benzoxazoles; Buffers; Cations, Divalent; Cell Adhesion; Cells, Cultured; Drug Interactions; Enzyme Inhibitors; Ethidium; Fluorescent Dyes; Humans; Kinetics; Mice; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Quinolinium Compounds; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Rosaniline Dyes; Serum Albumin, Bovine; Sodium Chloride; Species Specificity; Temperature	2001
Pharmacological characterization of the P2X(7) receptor on human macrophages using the patch-clamp technique. Naunyn-Schmiedeberg's archives of pharmacology, 2002, Volume: 365, Issue:2 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Cells, Cultured; Electrophysiology; Humans; Macrophages; Monocytes; Patch-Clamp Techniques; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Rosaniline Dyes	2002
Enhanced P2X7 activity in human fibroblasts from diabetic patients: a possible pathogenetic mechanism for vascular damage in diabetes. Arteriosclerosis, thrombosis, and vascular biology, 2004, Volume: 24, Issue:7 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Diphosphate; Adenosine Triphosphate; Apoptosis; Apyrase; Autocrine Communication; Cell Shape; Cytidine Triphosphate; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Fibroblasts; Fibronectins; Gene Expression Regulation; Humans; Interleukin-6; Membrane Potentials; Paracrine Communication; Pyridoxal Phosphate; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Uridine Diphosphate; Uridine Triphosphate	2004
Human epidermal and monocyte-derived langerhans cells express functional P2X receptors. The Journal of investigative dermatology, 2005, Volume: 125, Issue:3 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Biological Transport; Epidermal Cells; Ethidium; Humans; Keratinocytes; Langerhans Cells; Monocytes; Polymorphism, Genetic; Receptors, IgE; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Skin	2005
Multiple P2X receptors are involved in the modulation of apoptosis in human mesangial cells: evidence for a role of P2X4. American journal of physiology. Renal physiology, 2007, Volume: 292, Issue:5 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Apoptosis; Calcium; Caspase 3; Cell Membrane; Cells, Cultured; Dose-Response Relationship, Drug; Drug Synergism; Electrophysiology; Enzyme Activation; Extracellular Fluid; Flow Cytometry; Humans; Intracellular Membranes; Mesangial Cells; Microscopy, Phase-Contrast; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2X4; Receptors, Purinergic P2X7; Time Factors	2007
Contribution of two ionotropic purinergic receptors to ATP responses in submandibular gland ductal cells. Cellular signalling, 2007, Volume: 19, Issue:10 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Animals; Biological Transport; Calcium; Carbachol; Ethidium; Interleukin-1beta; Mice; Mice, Knockout; Phospholipases A2; Receptors, Purinergic P2; Receptors, Purinergic P2X4; Receptors, Purinergic P2X7; Saliva; Submandibular Gland	2007
Functional expression of ionotropic purinergic receptors on mouse taste bud cells. The Journal of physiology, 2007, Oct-15, Volume: 584, Issue:Pt 2 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Animals; Calcium Signaling; Fluorescent Dyes; Immunohistochemistry; In Vitro Techniques; Isoquinolines; Membrane Potentials; Mice; Microscopy, Fluorescence; Patch-Clamp Techniques; Pyridoxal Phosphate; Receptors, Purinergic P2; Receptors, Purinergic P2X2; Receptors, Purinergic P2X7; Receptors, Purinergic P2Y1; Reverse Transcriptase Polymerase Chain Reaction; Taste; Taste Buds; Thionucleotides; Time Factors; Uridine Triphosphate	2007
Cloning and pharmacological characterization of the guinea pig P2X7 receptor orthologue. British journal of pharmacology, 2008, Volume: 153, Issue:3 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Amino Acid Sequence; Animals; Cloning, Molecular; Guinea Pigs; Humans; Mice; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Rosaniline Dyes; Species Specificity; Suramin	2008
Negative and positive allosteric modulators of the P2X(7) receptor. British journal of pharmacology, 2008, Volume: 153, Issue:4 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Allosteric Regulation; Animals; Binding Sites; Cell Line; Dose-Response Relationship, Drug; Ethidium; Glycine; Humans; Molecular Structure; Piperazines; Protein Conformation; Pyridoxal Phosphate; Quinolines; Radioligand Assay; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Recombinant Proteins; Species Specificity; Time Factors; Transfection; Vanadates	2008
P2X7 receptor-Pannexin1 complex: pharmacology and signaling. American journal of physiology. Cell physiology, 2008, Volume: 295, Issue:3 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Animals; Carbenoxolone; Cell Line; Cell Membrane Permeability; Connexins; Dose-Response Relationship, Drug; Flufenamic Acid; Gap Junctions; Humans; Macrophages; Mefloquine; Membrane Potentials; Mice; Nerve Tissue Proteins; Oocytes; Phosphorylation; Receptors, Purinergic P2; Receptors, Purinergic P2X7; RNA Interference; RNA, Small Interfering; Signal Transduction; src-Family Kinases; Xenopus	2008
The role of P2X7 receptor in ATP-mediated human leukemia cell death: calcium influx-independent. Acta biochimica et biophysica Sinica, 2009, Volume: 41, Issue:5 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Apoptosis; Benzoxazoles; Biological Transport; Calcium; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Flow Cytometry; Humans; Leukemia; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Quinolinium Compounds; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Spectrometry, Fluorescence; Time Factors	2009
Pharmacological properties of the rhesus macaque monkey P2X7 receptor. British journal of pharmacology, 2011, Volume: 164, Issue:2b Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Amino Acid Sequence; Animals; Benzoxazoles; HEK293 Cells; Humans; Macaca mulatta; Membrane Potentials; Molecular Sequence Data; Patch-Clamp Techniques; Purinergic P2X Receptor Agonists; Purinergic P2X Receptor Antagonists; Pyridines; Quinolinium Compounds; Receptors, Purinergic P2X7; Single-Cell Analysis; Tetrazoles; Thiazoles	2011
Purinergic P2X7 receptors participate in disturbed intracellular calcium homeostasis in peripheral blood mononuclear cells of patients with chronic kidney disease. Kidney & blood pressure research, 2012, Volume: 35, Issue:1 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Adult; Calcium Signaling; Female; Homeostasis; Humans; Intracellular Fluid; Leukocytes, Mononuclear; Male; Middle Aged; Receptors, Purinergic P2X7; Renal Insufficiency, Chronic	2012
Adipocyte P2X7 receptors expression: a role in modulating inflammatory response in subjects with metabolic syndrome? Atherosclerosis, 2011, Volume: 219, Issue:2 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Adipocytes; Aged; Blotting, Western; Calcium Signaling; Case-Control Studies; Cells, Cultured; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique; Humans; Inflammasomes; Inflammation; Inflammation Mediators; Interleukin-6; Intra-Abdominal Fat; Italy; Metabolic Syndrome; Middle Aged; Plasminogen Activator Inhibitor 1; Purinergic P2X Receptor Agonists; Purinergic P2X Receptor Antagonists; Real-Time Polymerase Chain Reaction; Receptors, Purinergic P2X7; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Messenger; Subcutaneous Fat; Tumor Necrosis Factor-alpha; Up-Regulation	2011
IL-18 associates to microvesicles shed from human macrophages by a LPS/TLR-4 independent mechanism in response to P2X receptor stimulation. European journal of immunology, 2012, Volume: 42, Issue:12 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetamides; Adenosine Triphosphate; Anti-Bacterial Agents; Calcimycin; Calcium Ionophores; Cell-Derived Microparticles; Humans; Interleukin-18; Lipopolysaccharides; Macrophages; Polymyxin B; Protein Precursors; Purinergic P2X Receptor Agonists; Purinergic P2X Receptor Antagonists; Pyridines; Quinolines; Receptors, Purinergic P2X4; Receptors, Purinergic P2X7; Sulfonamides; Tetrazoles; Toll-Like Receptor 4	2012
Subcellular distribution and early signalling events of P2X7 receptors from mouse cerebellar granule neurons. European journal of pharmacology, 2014, Dec-05, Volume: 744 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Animals; Calcium; Cells, Cultured; Cerebellum; Fura-2; Glutamic Acid; Mice; Mice, Inbred C57BL; Neurons; Purinergic P2X Receptor Antagonists; Pyridines; Receptors, Purinergic P2X7; Tetrazoles	2014