1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 7 (70.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nakamura, M; Seki, T; Sperelakis, N; Sunagawa, M; Yokoshiki, H | 1 |
| Ikegami, K; Koike, T | 1 |
| Corcos, L; Galisteo, M; Guillouzo, A; Joannard, F; Lagadic-Gossmann, D | 1 |
| Bhat-Nakshatri, P; Nakshatri, H; Sweeney, CJ | 1 |
| Blanquet, PR; Derer, P; Mariani, J | 1 |
| Kim, SH; Kim, TS; Oh, SM | 1 |
| Miao, B; Pei, DS; Yin, XH; Zhang, GY; Zhang, QG | 1 |
| Horiuchi, N; Maeda, T | 1 |
| Li, J; Li, Y; Liu, M; Tao, J; Wei, M; Xin, P; Zhu, W | 1 |
| Ehrenreich, H; Heibeck, S; Heinrich, R; Jarrar, M; Micke, M; Miljus, N; Ostrowski, D | 1 |
10 other study(ies) available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one
| Article | Year |
|---|---|
Angiotensin II stimulation of Ca2+-channel current in vascular smooth muscle cells is inhibited by lavendustin-A and LY-294002.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Angiotensin II; Animals; Aorta; Calcium Channels; Cell Line; Chromones; Electric Conductivity; Enzyme Inhibitors; Kinetics; Morpholines; Phenols; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Rats | 1999 |
Membrane depolarization-mediated survival of sympathetic neurons occurs through both phosphatidylinositol 3-kinase- and CaM kinase II-dependent pathways.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Animals, Newborn; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cell Survival; Cells, Cultured; Chromones; Drug Synergism; Enzyme Inhibitors; Ganglia, Sympathetic; Membrane Potentials; Morpholines; Nerve Growth Factor; Neurons; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Rats | 2000 |
Regulation of phenobarbital-induction of CYP2B and CYP3A genes in rat cultured hepatocytes: involvement of several serine/threonine protein kinases and phosphatases.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Aryl Hydrocarbon Hydroxylases; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Chromones; Cyclic AMP; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Enzyme Induction; Enzyme Inhibitors; Flavonoids; Genistein; Hepatocytes; Hydroquinones; Indoles; Intracellular Fluid; Morpholines; Okadaic Acid; Oxidoreductases, N-Demethylating; Phenobarbital; Phosphoric Monoester Hydrolases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Rats; RNA, Messenger; Signal Transduction | 2000 |
Identification of signal transduction pathways involved in constitutive NF-kappaB activation in breast cancer cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Blotting, Western; Breast Neoplasms; Cell Survival; Chromones; Cyclic AMP-Dependent Protein Kinases; Electrophoretic Mobility Shift Assay; ErbB Receptors; Flavonoids; Gene Expression Regulation, Neoplastic; I-kappa B Kinase; Mice; Mice, Transgenic; Morpholines; Neuregulin-1; NF-kappa B; Oncogene Protein p21(ras); Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-myc; Receptor, ErbB-2; Signal Transduction; Transcription, Genetic; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2002 |
A calcium/calmodulin kinase pathway connects brain-derived neurotrophic factor to the cyclic AMP-responsive transcription factor in the rat hippocampus.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetophenones; Alkaloids; Androstadienes; Animals; Antibodies; Benzophenanthridines; Benzopyrans; Blotting, Western; Brain-Derived Neurotrophic Factor; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Carbazoles; Cell Nucleus; Chromones; Cyclic AMP Response Element-Binding Protein; Cytosol; Enzyme Inhibitors; Flavonoids; Hippocampus; Imidazoles; Immunohistochemistry; In Vitro Techniques; Indoles; Intracellular Signaling Peptides and Proteins; Male; Morpholines; Naphthalenes; Phenanthridines; Phosphorylation; Precipitin Tests; Protein Serine-Threonine Kinases; Pyridines; Pyrroles; Rats; Signal Transduction; Time Factors; Tyrphostins; Wortmannin | 2003 |
Induction of human leukemia HL-60 cell differentiation via a PKC/ERK pathway by helenalin, a pseudoguainolide sesquiterpene lactone.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Androstadienes; Antineoplastic Agents, Phytogenic; Benzophenanthridines; Cell Differentiation; Cell Proliferation; Chromones; Dose-Response Relationship, Drug; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; HL-60 Cells; Humans; Indoles; Lactones; Maleimides; Models, Biological; Morpholines; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phenanthridines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Sesquiterpenes; Sesquiterpenes, Guaiane; Signal Transduction; Wortmannin | 2005 |
Neuroprotective effects of preconditioning ischemia on ischemic brain injury through down-regulating activation of JNK1/2 via N-methyl-D-aspartate receptor-mediated Akt1 activation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Blotting, Western; Brain; Chromones; Down-Regulation; Enzyme Inhibitors; Ischemic Preconditioning; Ketamine; Male; MAP Kinase Kinase Kinases; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinase 9; Mitogen-Activated Protein Kinase Kinase Kinase 11; Morpholines; Neurons; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Binding; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Time Factors | 2005 |
Simvastatin suppresses leptin expression in 3T3-L1 adipocytes via activation of the cyclic AMP-PKA pathway induced by inhibition of protein prenylation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3T3-L1 Cells; Adipocytes; Androstadienes; Animals; Benzamides; Cell Differentiation; Chromones; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Enzyme-Linked Immunosorbent Assay; Gene Expression; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Isoquinolines; Leptin; Methionine; Mevalonic Acid; Mice; Morpholines; Polyisoprenyl Phosphates; Protein Prenylation; Protein Synthesis Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Simvastatin; Sulfonamides; Wortmannin | 2009 |
Fasudil protects the heart against ischemia-reperfusion injury by attenuating endoplasmic reticulum stress and modulating SERCA activity: the differential role for PI3K/Akt and JAK2/STAT3 signaling pathways.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Apoptosis; Cardiotonic Agents; Caspase 12; Chromones; DNA-Binding Proteins; Endoplasmic Reticulum Stress; Heat-Shock Proteins; Janus Kinase 2; Male; Morpholines; Myocardial Reperfusion Injury; Myocardium; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Isoforms; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Signal Transduction; STAT3 Transcription Factor; Transcription Factors | 2012 |
Erythropoietin-mediated protection of insect brain neurons involves JAK and STAT but not PI3K transduction pathways.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Apoptosis; Brain; Cell Survival; Cells, Cultured; Chromones; Enzyme Inhibitors; Erythropoietin; Grasshoppers; Humans; Hypoxia; Insect Proteins; Janus Kinase 2; Morpholines; Neurons; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Signal Transduction; STAT Transcription Factors; Tyrphostins | 2014 |