1-(5-isoquinolinesulfonyl)-2-methylpiperazine and 15-hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic acid

1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with 15-hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic acid in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.69)18.7374
1990's6 (46.15)18.2507
2000's4 (30.77)29.6817
2010's1 (7.69)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Chiyotani, A; Isono, K; Kondo, M; Konno, K; Sakai, N; Tamaoki, J1
Fujii, T; Hashizume, T; Sato, T1
Boehm, A; Halushka, PV; Mais, DE1
Craven, PA; DeRubertis, FR; Studer, RK1
Chan, CF; Chang, YL; Jiang, MJ1
Chua, BH; Chua, CC; Hamdy, RC1
Hashimoto, Y; Higashihara, M; Kurokawa, K; Satoh, H; Sunaga, S; Togo, M; Watanabe, T1
Bauer, J; Parekh, N1
Deng, P; Epstein, DL; Rao, PV; Sasaki, Y1
Shimoda, LA; Sylvester, JT; Weigand, L1
Badejo, AM; Casey, DB; Dhaliwal, JS; Gallen, TB; Greco, AJ; Kadowitz, PJ1
Blanco, CE; Villamor, E; Zoer, B1
Deli, MA; Fujimoto, T; Izumo, T; Matsunaga, Y; Matsuo, T; Morofuji, Y; Nakagawa, S; Niwa, M; Santa-Maria, AR; Sato, K; Vigh, JP; Walter, FR; Watanabe, D1

Other Studies

13 other study(ies) available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and 15-hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic acid

ArticleYear
Thromboxane A2 mimetic U46619 stimulates ciliary motility of rabbit tracheal epithelial cells.
    Prostaglandins, 1992, Volume: 43, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Cilia; Cyclic AMP; Dose-Response Relationship, Drug; Epithelial Cells; Epithelium; Fatty Acids, Unsaturated; Hydrazines; Isoproterenol; Isoquinolines; Male; Movement; Piperazines; Prostaglandin Endoperoxides, Synthetic; Protein Kinase C; Rabbits; Thromboxane A2; Trachea; Verapamil

1992
Sphingosine enhances platelet aggregation through an increase in phospholipase C activity by a protein kinase C-independent mechanism.
    The Biochemical journal, 1992, Feb-15, Volume: 282 ( Pt 1)

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Alkaloids; Animals; Arachidonic Acid; Blood Platelets; Calcium; Cell Membrane; Inositol 1,4,5-Trisphosphate; Isoquinolines; Kinetics; Piperazines; Platelet Activating Factor; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Protein Kinase C; Rabbits; Sphingosine; Staurosporine; Thrombin; Type C Phospholipases

1992
Polymyxin B increases TXA2/PGH2 agonist and antagonist affinities in human platelet membranes.
    Eicosanoids, 1988, Volume: 1, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Blood Platelets; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Fatty Acids, Unsaturated; Humans; Hydrazines; In Vitro Techniques; Isoquinolines; Piperazines; Polymyxin B; Polymyxins; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Prostaglandins H; Protein Kinase Inhibitors; Receptors, Prostaglandin; Receptors, Thromboxane; Receptors, Thromboxane A2, Prostaglandin H2; Thromboxane A2

1988
Impaired nitric oxide-dependent cyclic guanosine monophosphate generation in glomeruli from diabetic rats. Evidence for protein kinase C-mediated suppression of the cholinergic response.
    The Journal of clinical investigation, 1994, Volume: 93, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Alkaloids; Amino Acid Oxidoreductases; Animals; Arginine; Calcimycin; Carbachol; Cyclic GMP; Diabetes Mellitus, Experimental; Female; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Isoquinolines; Kidney Glomerulus; Kinetics; Membrane Proteins; Myristoylated Alanine-Rich C Kinase Substrate; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Phosphates; Phosphorylation; Piperazines; Prostaglandin Endoperoxides, Synthetic; Protein Kinase C; Proteins; Rats; Rats, Sprague-Dawley; Staurosporine; Thromboxane A2

1994
Intracellular calcium and myosin light chain phosphorylation during U46619-activated vascular contraction.
    Life sciences, 1994, Volume: 54, Issue:25

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Calcium; Guinea Pigs; In Vitro Techniques; Isoquinolines; Male; Muscle Contraction; Muscle, Smooth, Vascular; Myosins; Naphthalenes; Phosphorylation; Piperazines; Polycyclic Compounds; Prostaglandin Endoperoxides, Synthetic; Protein Kinase C; Thromboxane A2; Vasoconstriction; Vasoconstrictor Agents

1994
Regulation of endothelin-1 production by a thromboxane A2 mimetic in rat heart smooth muscle cells.
    Biochimica et biophysica acta, 1996, Aug-21, Volume: 1313, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Endothelins; Fatty Acids, Unsaturated; Gene Expression; Hydrazines; Isoquinolines; Muscle, Smooth; Myocardium; Piperazines; Promoter Regions, Genetic; Prostaglandin Endoperoxides, Synthetic; Protein Kinase C; Rats; Receptors, Thromboxane; RNA, Messenger; Thromboxane A2

1996
Protein kinase C plays a key role in the cross-talk between intracellular signalings via prostanoid receptors in a megakaryoblastic cell line, MEG-01s.
    Biochimica et biophysica acta, 1996, Nov-22, Volume: 1304, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Calcium; Cell Line; Cyclic AMP; Dinoprostone; Hematopoietic Stem Cells; Humans; Iloprost; Ionomycin; Megakaryocytes; Prostaglandin Endoperoxides, Synthetic; Protein Kinase C; Receptors, Prostaglandin; Receptors, Thrombin; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Thrombin; Thromboxane A2

1996
Variations in cell signaling pathways for different vasoconstrictor agonists in renal circulation of the rat.
    Kidney international, 2003, Volume: 63, Issue:6

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amides; Angiotensin II; Animals; Arginine Vasopressin; Blood Pressure; Calcium Channel Blockers; Enzyme Inhibitors; Female; Gallic Acid; Indoles; Nifedipine; Norepinephrine; Pyridines; Rats; Rats, Wistar; Renal Circulation; Signal Transduction; Staurosporine; Vasoconstrictor Agents

2003
Regulation of myosin light chain phosphorylation in the trabecular meshwork: role in aqueous humour outflow facility.
    Experimental eye research, 2005, Volume: 80, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Angiotensin II; Aqueous Humor; Cells, Cultured; Endothelin-1; Enzyme Inhibitors; GTP-Binding Protein alpha Subunits, G12-G13; Humans; Intracellular Signaling Peptides and Proteins; Muscle Proteins; Myosin Light Chains; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Reverse Transcriptase Polymerase Chain Reaction; rho GTP-Binding Proteins; rho-Associated Kinases; Trabecular Meshwork

2005
Mechanisms of endothelin-1-induced contraction in pulmonary arteries from chronically hypoxic rats.
    American journal of physiology. Lung cellular and molecular physiology, 2006, Volume: 290, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amides; Animals; Azepines; Endothelin-1; Enzyme Inhibitors; Genistein; Hypoxia; Indoles; Intracellular Signaling Peptides and Proteins; Isometric Contraction; Male; Maleimides; Myosin-Light-Chain Kinase; Potassium Chloride; Protein Kinase C; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Pulmonary Artery; Pyridines; Pyrimidines; Rats; Rats, Wistar; rho-Associated Kinases; src-Family Kinases; Staurosporine; Vasoconstriction

2006
Analysis of pulmonary vasodilator responses to the Rho-kinase inhibitor fasudil in the anesthetized rat.
    American journal of physiology. Lung cellular and molecular physiology, 2008, Volume: 295, Issue:5

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Anesthesia; Angiotensin II; Animals; Blood Gas Analysis; Blood Pressure; Cardiac Output; Heart Rate; Hypoxia; Injections, Intravenous; Isradipine; Lung; Male; NG-Nitroarginine Methyl Ester; Protein Kinase Inhibitors; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Vascular Resistance; Vasodilator Agents

2008
Role of Rho-kinase in mediating contraction of chicken embryo femoral arteries.
    Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 2010, Volume: 180, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Benzophenanthridines; Body Weight; Calcium; Chick Embryo; Egtazic Acid; Endothelin-1; Enzyme Inhibitors; Femoral Artery; Hypoxia; NG-Nitroarginine Methyl Ester; Oxadiazoles; Phenylephrine; Phorbol 12,13-Dibutyrate; Potassium Chloride; Protein Kinase C; Protein Kinase Inhibitors; Quinoxalines; rho-Associated Kinases; Vasoconstriction

2010
Effects of fasudil on blood-brain barrier integrity.
    Fluids and barriers of the CNS, 2022, Jun-03, Volume: 19, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Astrocytes; Blood-Brain Barrier; Endothelial Cells; Glucose; Humans; Ischemic Stroke; Rats; Tight Junction Proteins

2022