1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with 1-methyl-3-isobutylxanthine in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (10.34) | 18.7374 |
| 1990's | 24 (82.76) | 18.2507 |
| 2000's | 2 (6.90) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ballard, PL; Duffy, DM; Goldfien, A; Roberts, JM | 1 |
| Amador, M; Dani, JA; Moorman, JR; Pinkham, J; Reuhl, TO | 1 |
| Marumo, F; Nonoguchi, H; Tomita, K | 1 |
| Haneda, M; Horide, N; Kajiwara, N; Kikkawa, R; Koya, D; Maeda, S; Shigeta, Y; Togawa, M | 1 |
| Johnson, AL; Tilly, JL | 1 |
| Bomsztyk, K; Ostrowski, J | 1 |
| Hui, KK; Yu, JL | 1 |
| Cheung, HS; Mitchell, PG | 1 |
| Carter, DA | 1 |
| Craven, PA; DeRubertis, FR; Studer, RK | 1 |
| Kachra, Z; Posner, BI; Yang, CR | 1 |
| Iitaka, M; Ishii, J; Kitahama, S | 1 |
| Basavappa, S; Liddle, RA; Mangel, AW; Prpic, V | 1 |
| Chik, CL; Ho, AK; Inukai, T | 1 |
| Azimi, S; Hamdani, S; Laborde, K; Sachs, C; Shahedi, M | 1 |
| Hinds, TR; Storm, DR; Wayman, GA | 1 |
| Burnside, B; Liepe, BA | 1 |
| Nishida, A; Shimizu, M; Yamawaki, S | 1 |
| Dehaye, JP; Turner, RJ; Valdez, IH | 1 |
| Hughes, AK; Kohan, DE; Padilla, E | 1 |
| Dobson, JG; Ethier, MF | 1 |
| Marunaka, Y; Niisato, N | 1 |
| Lochter, A; Schachner, M | 1 |
| Copenhagen, DR; Dixon, DB | 1 |
| Braganza, JM; Jaran, AS; Quesnel, LB | 1 |
| Green, CB; Whalen, MM | 1 |
| Choi, BH; Earm, YE; Ho, WK; Lee, SH; Yeom, JB; Yoo, S | 1 |
| Baldelli, P; Carabelli, V; Carbone, E; Hernández-Guijo, JM | 1 |
| Darszon, A; Labarca, P; Sánchez, D | 1 |
29 other study(ies) available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and 1-methyl-3-isobutylxanthine
| Article | Year |
|---|---|
Cyclic adenosine 3',5'-monophosphate increases beta-adrenergic receptor concentration in cultured human fetal lung explants and type II cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Culture Techniques; Cyclic AMP; Fetal Organ Maturity; Humans; Isoquinolines; Lung; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Receptors, Adrenergic, beta | 1992 |
Nicotinic acetylcholine receptors are directly affected by agents used to study protein phosphorylation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cells, Cultured; Ion Channels; Isoquinolines; Membrane Potentials; Nicotinic Antagonists; Oocytes; Phosphorylation; Piperazines; Protein Kinase Inhibitors; Protein Kinases; Proteins; Receptors, Nicotinic; RNA, Messenger; Sulfonamides; Xenopus | 1992 |
Effects of endothelin on peptide-dependent cyclic adenosine monophosphate accumulation along the nephron segments of the rat.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Animals; Arginine Vasopressin; Calcitonin; Calcium; Cyclic AMP; Endothelins; Glucagon; In Vitro Techniques; Indomethacin; Isoproterenol; Isoquinolines; Kidney Tubules; Loop of Henle; Nicardipine; Parathyroid Hormone; Peptides; Piperazines; Protein Kinase C; Rats | 1990 |
Dual mechanism of angiotensin II inhibits ANP-induced mesangial cGMP accumulation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-GMP Phosphodiesterases; Angiotensin II; Animals; Atrial Natriuretic Factor; Cells, Cultured; Cyclic GMP; Glomerular Mesangium; Guanylate Cyclase; Isoquinolines; Kinetics; Piperazines; Protein Kinase C; Tetradecanoylphorbol Acetate | 1991 |
Effects of a phorbol ester, a calcium ionophore, and 3',5'-adenosine monophosphate production on hen granulosa cell plasminogen activator activity.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Animals; Calcimycin; Chickens; Cyclic AMP; Cycloheximide; Dactinomycin; Female; Granulosa Cells; In Vitro Techniques; Isoquinolines; L-Lactate Dehydrogenase; Luteinizing Hormone; Piperazines; Plasminogen Activators; Progesterone; Protein Kinase C; Sheep; Tetradecanoylphorbol Acetate | 1988 |
Interaction of signal transduction pathways in mediating acid secretion by rat parietal cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Aminopyrine; Animals; Bucladesine; Cell Membrane; Diglycerides; Female; Gastric Acid; Histamine; Isoquinolines; Parietal Cells, Gastric; Piperazines; Protein Kinase C; Rats; Rats, Inbred Strains; Signal Transduction; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1989 |
Effects of protein kinase inhibitor, 1-(5-isoquinolinylsulfonyl)-2-methylpiperazine, on beta-2 adrenergic receptor activation and desensitization in intact human lymphocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Adult; Cyclic AMP; Drug Synergism; Humans; Iodocyanopindolol; Isoproterenol; Isoquinolines; Lymphocytes; Pindolol; Piperazines; Protein Kinase Inhibitors; Receptors, Adrenergic, beta; Tetradecanoylphorbol Acetate | 1989 |
Protein kinase regulation of tumor necrosis factor alpha stimulated collagenase and stromelysin message levels in chondrocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Animals; Blotting, Northern; Cartilage, Articular; Cell Membrane; Cells, Cultured; Colforsin; Collagenases; Cyclic AMP; Enzyme Induction; Gene Expression Regulation; Isoquinolines; Kinetics; Matrix Metalloproteinase 3; Metalloendopeptidases; Neoplasm Proteins; Piperazines; Protein Kinase C; Recombinant Proteins; RNA, Messenger; Swine; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1993 |
Noradrenergic regulation of c-jun expression in the rat pineal gland in culture: positive and negative components.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Animals; Colforsin; Gene Expression Regulation; Isoquinolines; Male; Norepinephrine; Organ Culture Techniques; Phorbol 12,13-Dibutyrate; Pineal Gland; Piperazines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-jun; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; RNA, Messenger; Sulfonamides | 1993 |
Impaired nitric oxide-dependent cyclic guanosine monophosphate generation in glomeruli from diabetic rats. Evidence for protein kinase C-mediated suppression of the cholinergic response.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Alkaloids; Amino Acid Oxidoreductases; Animals; Arginine; Calcimycin; Carbachol; Cyclic GMP; Diabetes Mellitus, Experimental; Female; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Isoquinolines; Kidney Glomerulus; Kinetics; Membrane Proteins; Myristoylated Alanine-Rich C Kinase Substrate; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Phosphates; Phosphorylation; Piperazines; Prostaglandin Endoperoxides, Synthetic; Protein Kinase C; Proteins; Rats; Rats, Sprague-Dawley; Staurosporine; Thromboxane A2 | 1994 |
The augmentation of insulin-like growth factor-I messenger ribonucleic acid in cultured rat hepatocytes: activation of protein kinase-A and -C is necessary, but not sufficient.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Alkaloids; Animals; Blotting, Northern; Bucladesine; Cattle; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Drug Synergism; Enzyme Activation; Glucagon; Growth Hormone; Insulin-Like Growth Factor I; Isoquinolines; Kinetics; Liver; Male; Piperazines; Protein Kinase C; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate | 1994 |
Involvement of protein kinase A and C in the production of interleukin-1 alpha-induced prostaglandin E2 from mouse osteoblast-like cell line, MC3T3-E1.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; 3T3 Cells; 8-Bromo Cyclic Adenosine Monophosphate; Alkaloids; Animals; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Dinoprostone; Humans; Indoles; Indomethacin; Interleukin-1; Isoquinolines; Kinetics; Mice; Osteoblasts; Piperazines; Protein Kinase C; Pyrroles; Recombinant Proteins; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate | 1994 |
Regulation of cholecystokinin secretion by calcium-dependent calmodulin kinase II: differential effects of phenylalanine and cAMP.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cholecystokinin; Cyclic AMP; Diltiazem; In Vitro Techniques; Intestinal Mucosa; Isoquinolines; Mice; Phenylalanine; Piperazines; Secretory Rate | 1994 |
Vasoactive intestinal polypeptide stimulates cyclic AMP production in mouse N1E-115 neuroblastoma cells: modulation by a protein kinase C activator and ionomycin.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Animals; Calcium; Carcinogens; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Enzyme Activation; Ionomycin; Isoquinolines; Kinetics; Mice; Neuroblastoma; Phorbol Esters; Piperazines; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vasoactive Intestinal Peptide | 1994 |
Mechanisms of dopamine effects on Na-K-ATPase activity in Madin-Darby canine kidney (MDCK) epithelial cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 3',5'-Cyclic-AMP Phosphodiesterases; Amiloride; Animals; Cell Line; Cyclic AMP-Dependent Protein Kinases; Dideoxyadenosine; Dogs; Domperidone; Dopamine; Dopamine D2 Receptor Antagonists; Epithelium; Ergolines; Furosemide; Isoquinolines; Kidney; Kidney Tubules, Collecting; Piperazines; Protein Kinase C; Quinpirole; Receptors, Dopamine D1; Sodium-Potassium-Exchanging ATPase | 1995 |
Hormone stimulation of type III adenylyl cyclase induces Ca2+ oscillations in HEK-293 cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Calcium; Calcium Channels; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Cell Line; Colforsin; Cyclic AMP; Enzyme Activation; Enzyme Inhibitors; Glucagon; Humans; Inositol 1,4,5-Trisphosphate Receptors; Isoproterenol; Isoquinolines; Kidney; Kinetics; Models, Biological; Oscillometry; Phosphatidylinositols; Piperazines; Receptors, Cytoplasmic and Nuclear; Receptors, Glucagon; Signal Transduction; Time Factors | 1995 |
Cyclic nucleotide regulation of teleost rod photoreceptor inner segment length.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Actins; Animals; Cyclic AMP; Cyclic GMP; Cytoskeleton; Darkness; Ethers, Cyclic; In Vitro Techniques; Isoquinolines; Light; Okadaic Acid; Peptide Chain Elongation, Translational; Perciformes; Phosphoprotein Phosphatases; Photoreceptor Cells; Piperazines; Protein Kinase Inhibitors | 1993 |
Forskolin and phorbol myristate acetate inhibit intracellular Ca2+ mobilization induced by amitriptyline and bradykinin in rat frontocortical neurons.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Amitriptyline; Animals; Bradykinin; Bucladesine; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Frontal Lobe; Imipramine; Inositol 1,4,5-Trisphosphate; Isoquinolines; Kinetics; Neurons; Piperazines; Protein Kinase Inhibitors; Rats; Tetradecanoylphorbol Acetate | 1993 |
Beta-adrenergic stimulation and cAMP mobilize Ca2+ from an IP3-insensitive pool in rat submandibular granular ducts.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Adrenergic beta-Antagonists; Alkaloids; Animals; Atenolol; Atropine; Calcium; Carbachol; Cyclic AMP; Epinephrine; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Isoproterenol; Isoquinolines; Kinetics; Male; Phentolamine; Piperazines; Propanolamines; Propranolol; Protein Kinase C; Protein Kinase Inhibitors; Putrescine; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Staurosporine; Submandibular Gland | 1993 |
Endothelin B receptor mediates ET-1 effects on cAMP and PGE2 accumulation in rat IMCD.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Animals; Arginine Vasopressin; Binding, Competitive; Cell Line; Cells, Cultured; Cyclic AMP; Dinoprostone; Endothelin Receptor Antagonists; Endothelins; Isoquinolines; Kidney Medulla; Kidney Tubules, Collecting; Kinetics; Male; Peptides, Cyclic; Pertussis Toxin; Piperazines; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Receptor, Endothelin B; Receptors, Endothelin; Virulence Factors, Bordetella | 1993 |
Adenosine stimulation of DNA synthesis in human endothelial cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Triphosphate; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DNA; Endothelium, Vascular; Humans; Kinetics; Poly A; Purinergic P1 Receptor Antagonists; Quinazolines; Tetradecanoylphorbol Acetate; Thioinosine; Thionucleotides; Thymidine; Triazoles; Umbilical Veins | 1997 |
Regulation of Cl- transport by IBMX in renal A6 epithelium.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Animals; Calcium; Calcium Channel Blockers; Cell Line; Chloride Channels; Chlorides; Cyclic AMP; Cytosol; Enzyme Inhibitors; Epithelium; Ion Transport; Isoquinolines; Kidney; Kinetics; Nitrobenzoates; Phosphodiesterase Inhibitors; Protein Kinase Inhibitors; Sulfonamides; Xenopus laevis | 1997 |
Inhibitors of protein kinases abolish ECM-mediated promotion of neuronal polarity.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Alkaloids; Animals; Benzophenanthridines; Bucladesine; Cell Polarity; Cells, Cultured; Cyclic AMP; Dibutyryl Cyclic GMP; Embryo, Mammalian; Enzyme Inhibitors; Extracellular Matrix; Extracellular Matrix Proteins; Hippocampus; Neurites; Neurons; Phenanthridines; Protein Kinase Inhibitors; Rats; Rats, Inbred Strains; Signal Transduction; Vanadates | 1997 |
Metabotropic glutamate receptor-mediated suppression of an inward rectifier current is linked via a cGMP cascade.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine Triphosphate; Aminobutyrates; Animals; Atrial Natriuretic Factor; Benzoates; Cyclic GMP; Enzyme Inhibitors; Glutamic Acid; Glycine; Ictaluridae; Ion Channel Gating; Isoquinolines; Models, Neurological; Patch-Clamp Techniques; Photoreceptor Cells; Potassium Channels; Receptors, Metabotropic Glutamate; Second Messenger Systems; Thionucleotides | 1997 |
Antibiotic accumulation and membrane trafficking in cystic fibrosis cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Adenosine Triphosphate; Adenylyl Imidodiphosphate; Adult; Cell Membrane; Child; Child, Preschool; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Energy Metabolism; Female; Fluorescein-5-isothiocyanate; Gentamicins; Humans; Male; Middle Aged; Nasal Polyps; Thionucleotides | 1998 |
Lysis-sensitive targets stimulate an elevation of cAMP in human natural killer cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Alkaloids; Antineoplastic Agents; Benzophenanthridines; Cyclic AMP; Enzyme Inhibitors; Genistein; Humans; Killer Cells, Natural; Neoplasms; Phenanthridines; Phosphodiesterase Inhibitors; Protein Kinase C; Protein-Tyrosine Kinases; Tumor Cells, Cultured | 1998 |
Dual effect of nitric oxide on the hyperpolarization-activated inward current (I(f)) in sino-atrial node cells of the rabbit.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Acetylcholine; Adrenergic beta-Agonists; Animals; Electrophysiology; Enzyme Inhibitors; Female; Guanosine Monophosphate; Isoproterenol; Male; Methylene Blue; Nitric Oxide; Nitroprusside; Phosphodiesterase Inhibitors; Rabbits; Sinoatrial Node; Time Factors; Vasodilator Agents | 1998 |
Direct autocrine inhibition and cAMP-dependent potentiation of single L-type Ca2+ channels in bovine chromaffin cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Adenosine Triphosphate; Animals; Autocrine Communication; Calcium; Calcium Channels, L-Type; Cattle; Cells, Cultured; Chromaffin Cells; Colforsin; Cyclic AMP; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enzyme Inhibitors; GABA Antagonists; Isoquinolines; Kinetics; Naloxone; Narcotic Antagonists; Patch-Clamp Techniques; Picrotoxin; Protein Kinase Inhibitors; Sulfonamides; Suramin | 2001 |
Sea urchin sperm cation-selective channels directly modulated by cAMP.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Amino Acid Sequence; Animals; Cations; Cyclic AMP; Enzyme Inhibitors; Ion Channels; Male; Membrane Potentials; Protein Kinase Inhibitors; Sea Urchins; Spermatozoa | 2001 |