1-(4-methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)ethene has been researched along with stilbenes in 32 studies
| Studies (1-(4-methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)ethene) | Trials (1-(4-methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)ethene) | Recent Studies (post-2010) (1-(4-methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)ethene) | Studies (stilbenes) | Trials (stilbenes) | Recent Studies (post-2010) (stilbenes) |
|---|---|---|---|---|---|
| 30 | 0 | 23 | 13,935 | 245 | 7,836 |
| 11 | 0 | 2 | 13,935 | 245 | 7,836 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (6.25) | 18.2507 |
| 2000's | 5 (15.63) | 29.6817 |
| 2010's | 21 (65.63) | 24.3611 |
| 2020's | 4 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Cushman, M; Gopal, D; Hamel, E; He, HM; Lin, CM; Nagarathnam, D | 1 |
| Chakraborti, AK; Cushman, M; Gopal, D; Hamel, E; Lin, CM; Nagarathnam, D | 1 |
| Boocock, D; Farmer, PB; Gescher, AJ; Jones, DJ; Potter, GA; Ruparelia, KC; Sale, S; Steward, WP; Verschoyle, RD; Wilsher, N | 1 |
| Chen, KY; Chen, M; Gosslau, A; Ho, CT | 1 |
| Gescher, AJ; Potter, GA; Ruparelia, KC; Sale, S; Steward, WP; Tunstall, RG | 1 |
| Robinson, JE; Taylor, RJ | 1 |
| Gossage, RA; Haddadi, A; Lai, R; Lavasanifar, A; Ma, Z; Molavi, O | 1 |
| Go, ML; Ho, PC; Lin, HS; Spatafora, C; Tringali, C; Zhang, W | 1 |
| Androutsopoulos, VP; Filippakis, H; Papakyriakou, A; Ruparelia, KC; Spandidos, DA; Tsatsakis, AM | 1 |
| Jodynis-Liebert, J; Kaczmarek, M; Kulcenty, K; Kwiatkowska-Borowczyk, E; Murias, M; Myszkowski, K; Piotrowska, H; Wierzchowski, M; Ziółkowska, A | 1 |
| Chen, LK; Dai, F; Qiang, PF; Xu, QP; Zhang, L; Zhao, YH | 1 |
| Amarowicz, R; Jodynis-Liebert, J; Kulcenty, K; Murias, M; Myszkowski, K; Piotrowska, H; Wierzchowski, M | 1 |
| Baer-Dubowska, W; Cichocki, M; Jodynis-Liebert, J; Murias, M; Wierzchowski, M | 1 |
| Abraszek, J; Amarowicz, R; Jodynis-Liebert, J; Kwiatkowska-Borowczyk, E; Murias, M; Myszkowski, K; Piotrowska, H; Wierzchowski, M | 1 |
| Androutsopoulos, VP; Fragiadaki, I; Tosca, A | 1 |
| Crooks, PA; Penthala, NR; Thakkar, S | 1 |
| Chen, Z; Cui, L; Miao, Y; Zhang, L | 1 |
| Ding, J; Fan, XX; He, JX; Huang, J; Huang, M; Jiang, ZB; Kam, RK; Leung, EL; Liu, L; Michelangeli, F; Mujtaba, T; Wong, VK; Xiao, DK; Xu, SW; Xue, WW; Yao, XJ; Zhou, YL | 1 |
| Bostian, AC; Crooks, PA; Eoff, RL; Ketkar, A; Madadi, NR; Penthala, NR | 1 |
| Ignatowicz, E; Jodynis-Liebert, J; Krajka-Kuźniak, V; Kujawska, M; Murias, M; Nowicki, M; Petzke, E; Piotrowska, H; Wierzchowski, M; Zawierucha, P | 1 |
| Androutsopoulos, VP; Fragiadaki, I; Spandidos, DA; Tosca, A | 1 |
| Borys, S; Jodynis-Liebert, J; Kaczmarek, M; Kucińska, M; Murias, M; Piotrowska-Kempisty, H; Ruciński, M; Wierzchowski, M; Zawierucha, P; Łażewski, D | 1 |
| Baer-Dubowska, W; Jodynis-Liebert, J; Klupczyńska, A; Kokot, Z; Kucińska, M; Kulcenty, K; Mikstacka, R; Murias, M; Piotrowska-Kempisty, H; Sulej-Suchomska, AM; Trzybulska, D; Wierzchowski, M | 1 |
| Bachleda, P; Dvořák, Z; Pastorková, B; Vrzalová, A | 1 |
| Jodynis-Liebert, J; Klupczynska, A; Kokot, ZJ; Piotrowska-Kempisty, H; Sulej-Suchomska, AM; Wierzchowski, M | 1 |
| Braeuning, A; Dusek, J; Hirsova, P; Holas, O; Horvatova, A; Kucera, O; Linhartova, L; Micuda, S; Pavek, P; Skoda, J; Smutny, T | 1 |
| Jodynis-Liebert, J; Jozkowiak, M; Krajka-Kuzniak, V; Nowicki, A; Piotrowska-Kempisty, H; Ramlau, P; Rucinski, M; Skupin-Mrugalska, P; Wierzchowski, M | 1 |
| Borys-Wojcik, S; Jodynis-Liebert, J; Jozkowiak, M; Kaczmarek, M; Nowicki, A; Piotrowska-Kempisty, H; Ramlau, P; Skupin-Mrugalska, P; Wierzchowski, M | 1 |
| Czajkowski, M; Józkowiak, M; Nowicki, A; Pawlak, M; Piotrowska-Kempisty, H; Rolle, K; Skupin-Mrugalska, P; Wawrzyniak, D; Wierzchowski, M | 1 |
| Bryja, A; Czajkowski, M; Gogola-Mruk, J; Józkowiak, M; Kempisty, B; Kobylarek, D; Piotrowska-Kempisty, H; Skupin-Mrugalska, P; Spaczyński, RZ | 1 |
| Go, ML; Zhang, W | 1 |
| Alam, MS; Ismail, T; Khazir, J; Kumar, HM; Qurishi, Y; Sarkar, D; Shafi, S; Srinivas, J | 1 |
32 other study(ies) available for 1-(4-methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)ethene and stilbenes
| Article | Year |
|---|---|
Synthesis and evaluation of analogues of (Z)-1-(4-methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)ethene as potential cytotoxic and antimitotic agents.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Division; Colonic Neoplasms; Humans; Lung Neoplasms; Melanoma; Stilbenes; Structure-Activity Relationship; Tubulin; Tubulin Modulators; Tumor Cells, Cultured | 1992 |
Synthesis and evaluation of stilbene and dihydrostilbene derivatives as potential anticancer agents that inhibit tubulin polymerization.
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Chemical Phenomena; Chemistry; Colchicine; Colonic Neoplasms; Humans; Lung Neoplasms; Melanoma; Molecular Structure; Polymers; Stilbenes; Structure-Activity Relationship; Tubulin; Tubulin Modulators; Tumor Cells, Cultured | 1991 |
Pharmacokinetics in mice and growth-inhibitory properties of the putative cancer chemopreventive agent resveratrol and the synthetic analogue trans 3,4,5,4'-tetramethoxystilbene.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Chemoprevention; Colorectal Neoplasms; Drug Design; Hydroxylation; Isomerism; Mice; Resveratrol; Stilbenes; Tissue Distribution | 2004 |
A methoxy derivative of resveratrol analogue selectively induced activation of the mitochondrial apoptotic pathway in transformed fibroblasts.
Topics: Apoptosis; Cell Division; Cell Line, Transformed; Fibroblasts; Humans; Mitochondria; Resveratrol; Stilbenes; Tumor Cells, Cultured | 2005 |
Comparison of the effects of the chemopreventive agent resveratrol and its synthetic analog trans 3,4,5,4'-tetramethoxystilbene (DMU-212) on adenoma development in the Apc(Min+) mouse and cyclooxygenase-2 in human-derived colon cancer cells.
Topics: Adenoma; Animals; Antineoplastic Agents, Phytogenic; Chemoprevention; Colonic Neoplasms; Cyclooxygenase 2; Diet; Dinoprostone; Female; Genes, APC; Intestinal Mucosa; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Prostaglandin-Endoperoxide Synthases; Resveratrol; Ribonucleotide Reductases; Stilbenes; Tissue Distribution | 2005 |
A Ramberg-Bäcklund route to the stilbenoid anti-cancer agents combretastatin A-4 and DMU-212.
Topics: Antineoplastic Agents; Molecular Structure; Stilbenes; Sulfones | 2007 |
Resveratrol analog trans 3,4,5,4'-tetramethoxystilbene (DMU-212) mediates anti-tumor effects via mechanism different from that of resveratrol.
Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Biopolymers; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Estrogens; Female; Humans; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Resveratrol; STAT3 Transcription Factor; Stilbenes; Tubulin | 2008 |
Quantification of trans-3,4,5,4'-Tetramethoxystilbene in rat plasma by HPLC: application to pharmacokinetic study.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Chromatography, High Pressure Liquid; Half-Life; Injections, Intravenous; Male; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Stilbenes | 2011 |
Anticancer effects of the metabolic products of the resveratrol analogue, DMU-212: structural requirements for potency.
Topics: Antineoplastic Agents; Cell Cycle; Cell Proliferation; Computational Biology; Computer Simulation; Crystallography, X-Ray; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Hep G2 Cells; Humans; Models, Molecular; Molecular Structure; Stereoisomerism; Stilbenes; Structure-Activity Relationship; Tumor Cells, Cultured | 2011 |
Resveratrol analogue 3,4,4',5-tetramethoxystilbene inhibits growth, arrests cell cycle and induces apoptosis in ovarian SKOV-3 and A-2780 cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Apoptotic Protease-Activating Factor 1; bcl-2-Associated X Protein; Cell Cycle; Cell Line, Tumor; Female; Gene Expression Regulation, Neoplastic; Genes, bcl-2; Genes, Neoplasm; Genes, p53; Humans; Ovarian Neoplasms; Stilbenes | 2012 |
Trans-3,4,5,4'-tetramethoxystilbene, a resveratrol analog, potently inhibits angiogenesis in vitro and in vivo.
Topics: Angiogenesis Inhibitors; Animals; Cell Movement; Chick Embryo; Dose-Response Relationship, Drug; Human Umbilical Vein Endothelial Cells; Humans; Mice; Mice, Inbred C57BL; Neovascularization, Physiologic; Resveratrol; Stilbenes | 2013 |
Different susceptibility of colon cancer DLD-1 and LOVO cell lines to apoptosis induced by DMU-212, a synthetic resveratrol analogue.
Topics: Antineoplastic Agents; Apoptosis; Aryl Hydrocarbon Hydroxylases; Caspases; Cell Line, Tumor; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Humans; Resveratrol; Stilbenes | 2013 |
3,4,5,4'-trans-tetramethoxystilbene (DMU-212) modulates the activation of NF-κB, AP-1, and STAT3 transcription factors in rat liver carcinogenesis induced by initiation-promotion regimen.
Topics: Animals; Carcinogenesis; Cyclooxygenase 2; I-kappa B Proteins; Liver; Liver Neoplasms; Male; NF-kappa B; Nitric Oxide Synthase Type II; Rats, Wistar; STAT3 Transcription Factor; Stilbenes; Transcription Factor AP-1 | 2014 |
DMU-212 inhibits tumor growth in xenograft model of human ovarian cancer.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Female; Humans; Mice; Mice, SCID; Ovarian Neoplasms; Stilbenes; Time Factors; Tumor Burden; Xenograft Model Antitumor Assays | 2014 |
Activation of ERK1/2 is required for the antimitotic activity of the resveratrol analogue 3,4,5,4'-tetramethoxystilbene (DMU-212) in human melanoma cells.
Topics: Antineoplastic Agents; Cell Line, Tumor; Drug Screening Assays, Antitumor; Enzyme Activation; G2 Phase Cell Cycle Checkpoints; Humans; MAP Kinase Signaling System; Melanoma; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neoplasm Proteins; Phosphorylation; Protein Processing, Post-Translational; Protein Transport; Stilbenes | 2015 |
Heteroaromatic analogs of the resveratrol analog DMU-212 as potent anti-cancer agents.
Topics: Antineoplastic Agents; Benzofurans; Benzothiazoles; Binding Sites; Cell Line, Tumor; Cell Survival; Colchicine; Drug Screening Assays, Antitumor; Humans; Molecular Docking Simulation; Protein Structure, Tertiary; Resveratrol; Stilbenes; Thiophenes; Tubulin | 2015 |
Gene expression profiling of DMU-212-induced apoptosis and anti-angiogenesis in vascular endothelial cells.
Topics: Angiogenesis Inhibitors; Apoptosis; Endothelial Cells; Gene Expression Profiling; Human Umbilical Vein Endothelial Cells; Humans; Stilbenes | 2016 |
(Z)3,4,5,4'-trans-tetramethoxystilbene, a new analogue of resveratrol, inhibits gefitinb-resistant non-small cell lung cancer via selectively elevating intracellular calcium level.
Topics: Adenylate Kinase; Antineoplastic Agents; Apoptosis; Calcium; Cell Line, Tumor; Endoplasmic Reticulum Stress; Enzyme Activation; ErbB Receptors; Gefitinib; Humans; Quinazolines; Stilbenes | 2015 |
Dioxol and dihydrodioxin analogs of 2- and 3-phenylacetonitriles as potent anti-cancer agents with nanomolar activity against a variety of human cancer cells.
Topics: Acetonitriles; Antineoplastic Agents; Benzodioxoles; Cell Line, Tumor; Dioxanes; Drug Screening Assays, Antitumor; Humans; Molecular Docking Simulation; Stereoisomerism; Stilbenes; Tubulin Modulators | 2016 |
Effect of resveratrol analogue, DMU-212, on antioxidant status and apoptosis-related genes in rat model of hepatocarcinogenesis.
Topics: Animals; Antioxidants; Apoptosis; Liver Neoplasms, Experimental; Male; Oxidative Stress; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2017 |
The resveratrol analogue, 3,4,5,4'‑trans-tetramethoxystilbene, inhibits the growth of A375 melanoma cells through multiple anticancer modes of action.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Screening Assays, Antitumor; Gene Expression Regulation, Neoplastic; Humans; MAP Kinase Signaling System; Melanoma; Prometaphase; Stilbenes | 2016 |
3'-hydroxy-3,4,5,4'-tetramethoxystilbene, the metabolite of resveratrol analogue DMU-212, inhibits ovarian cancer cell growth in vitro and in a mice xenograft model.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Female; Genome, Human; Humans; Metabolome; Mice; Mice, SCID; Oligonucleotide Array Sequence Analysis; Ovarian Neoplasms; Real-Time Polymerase Chain Reaction; Resveratrol; Signal Transduction; Stilbenes; Tumor Burden; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays | 2016 |
Role of CYP1A1 in the biological activity of methylated resveratrol analogue, 3,4,5,4'-tetramethoxystilbene (DMU-212) in ovarian cancer A-2780 and non-cancerous HOSE cells.
Topics: Activation, Metabolic; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Dose-Response Relationship, Drug; Epithelial Cells; Female; Humans; Hydroxylation; Ovarian Neoplasms; RNA Interference; Stilbenes; Time Factors; Transfection | 2017 |
Hydroxystilbenes and methoxystilbenes activate human aryl hydrocarbon receptor and induce CYP1A genes in human hepatoma cells and human hepatocytes.
Topics: Adult; Aged; Basic Helix-Loop-Helix Transcription Factors; Cells, Cultured; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inducers; Gene Expression Regulation; Hep G2 Cells; Hepatocytes; Humans; Isomerism; Male; Middle Aged; Receptors, Aryl Hydrocarbon; Resveratrol; Stilbenes | 2017 |
Development and validation of HPLC-MS/MS procedure for determination of 3,4,4',5-tetra-methoxystilbene (DMU-212) and its metabolites in ovarian cancer cells and culture medium.
Topics: Cell Line, Tumor; Chromatography, High Pressure Liquid; Female; Humans; Limit of Detection; Linear Models; Ovarian Neoplasms; Reproducibility of Results; Stilbenes; Tandem Mass Spectrometry | 2017 |
Stilbene compound trans-3,4,5,4´-tetramethoxystilbene, a potential anticancer drug, regulates constitutive androstane receptor (Car) target genes, but does not possess proliferative activity in mouse liver.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Aryl Hydrocarbon Hydroxylases; Binding Sites; Cell Proliferation; Constitutive Androstane Receptor; Cytochrome P450 Family 2; Gene Expression Regulation, Enzymologic; Gluconeogenesis; Hep G2 Cells; Hepatocytes; Humans; Lipogenesis; Liver; Liver Neoplasms; Male; Mice, Inbred C57BL; Molecular Docking Simulation; Protein Binding; Pyridines; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Steroid Hydroxylases; Stilbenes | 2019 |
The Effect of 3'-Hydroxy-3,4,5,4'-Tetramethoxy -stilbene, the Metabolite of the Resveratrol Analogue DMU-212, on the Motility and Proliferation of Ovarian Cancer Cells.
Topics: Cell Line, Tumor; Cell Movement; Cell Proliferation; Female; Humans; Kruppel-Like Factor 4; Ovarian Neoplasms; Resveratrol; Stilbenes; Transcriptome | 2020 |
The Effect of 4'-hydroxy-3,4,5-trimetoxystilbene, the Metabolite of Resveratrol Analogue DMU-212, on Growth, Cell Cycle and Apoptosis in DLD-1 and LOVO Colon Cancer Cell Lines.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Caspases; Cell Cycle; Cell Division; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; G2 Phase; Humans; Signal Transduction; Stilbenes | 2020 |
Enhanced biological activity of liposomal methylated resveratrol analog 3'-hydroxy-3,4,5,4'-tetramethoxystilbene (DMU-214) in 3D patient-derived ovarian cancer model.
Topics: Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Female; Humans; Liposomes; Ovarian Neoplasms; Resveratrol; Stilbenes | 2022 |
Steroidogenic activity of liposomal methylated resveratrol analog 3,4,5,4'-tetramethoxystilbene (DMU-212) in human luteinized granulosa cells in a primary three-dimensional in vitro model.
Topics: Cholesterol Side-Chain Cleavage Enzyme; Estradiol; Female; Follicle Stimulating Hormone; Granulosa Cells; Humans; Liposomes; Multienzyme Complexes; Progesterone; Resveratrol; Stilbenes | 2023 |
Methoxylation of resveratrol: effects on induction of NAD(P)H quinone-oxidoreductase 1 (NQO1) activity and growth inhibitory properties.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Enzyme Inhibitors; Humans; Mice; NAD(P)H Dehydrogenase (Quinone); Resveratrol; Stilbenes; Structure-Activity Relationship | 2011 |
Synthesis and tyrosinase inhibition activity of trans-stilbene derivatives.
Topics: Animals; Cell Line, Tumor; Enzyme Inhibitors; Mice; Monophenol Monooxygenase; Resveratrol; Stilbenes; Structure-Activity Relationship | 2016 |