1-(4-methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)ethene has been researched along with fosbretabulin in 8 studies
| Studies (1-(4-methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)ethene) | Trials (1-(4-methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)ethene) | Recent Studies (post-2010) (1-(4-methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)ethene) | Studies (fosbretabulin) | Trials (fosbretabulin) | Recent Studies (post-2010) (fosbretabulin) |
|---|---|---|---|---|---|
| 30 | 0 | 23 | 588 | 21 | 310 |
| 11 | 0 | 2 | 497 | 0 | 320 |
| Protein | Taxonomy | 1-(4-methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)ethene (IC50) | fosbretabulin (IC50) |
|---|---|---|---|
| Tubulin polymerization-promoting protein | Homo sapiens (human) | 1.016 | |
| Tubulin alpha-1A chain | Sus scrofa (pig) | 1.82 | |
| Tubulin beta chain | Sus scrofa (pig) | 1.9428 | |
| Tubulin beta-4A chain | Homo sapiens (human) | 1.663 | |
| Tubulin beta chain | Homo sapiens (human) | 1.663 | |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | 0.009 | |
| Tubulin alpha-3C chain | Homo sapiens (human) | 1.663 | |
| Sodium-dependent serotonin transporter | Rattus norvegicus (Norway rat) | 1.08 | |
| Delta-type opioid receptor | Mus musculus (house mouse) | 1.005 | |
| Delta-type opioid receptor | Rattus norvegicus (Norway rat) | 0.81 | |
| Mu-type opioid receptor | Mus musculus (house mouse) | 1.2 | |
| Tubulin alpha-1B chain | Homo sapiens (human) | 1.663 | |
| Tubulin alpha-4A chain | Homo sapiens (human) | 1.663 | |
| Tubulin beta-4B chain | Homo sapiens (human) | 1.663 | |
| Vesicular acetylcholine transporter | Tetronarce californica (Pacific electric ray) | 1.8 | |
| Tubulin beta-3 chain | Homo sapiens (human) | 1.5801 | |
| Tubulin beta-2A chain | Homo sapiens (human) | 1.663 | |
| Beta-tubulin | Leishmania donovani | 1.95 | |
| Tubulin beta-8 chain | Homo sapiens (human) | 1.663 | |
| Tubulin beta-2B chain | Bos taurus (cattle) | 1.4484 | |
| Tubulin alpha-3E chain | Homo sapiens (human) | 1.663 | |
| Tubulin alpha-1A chain | Homo sapiens (human) | 1.663 | |
| Similar to alpha-tubulin isoform 1 | Bos taurus (cattle) | 1.4928 | |
| Similar to alpha-tubulin isoform 1 | Bos taurus (cattle) | 1.4037 | |
| Tubulin alpha-1C chain | Homo sapiens (human) | 1.663 | |
| Tubulin beta-6 chain | Homo sapiens (human) | 1.663 | |
| Tubulin beta-2B chain | Homo sapiens (human) | 1.663 | |
| Tubulin beta-1 chain | Homo sapiens (human) | 1.6366 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 5 (62.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chakraborti, AK; Cushman, M; Gopal, D; Hamel, E; Lin, CM; Nagarathnam, D | 1 |
| Robinson, JE; Taylor, RJ | 1 |
| Cushman, M; Gopal, D; Hamel, E; He, HM; Lin, CM; Nagarathnam, D | 1 |
| Boyd, MR; Hamel, E; Herald, DL; Pettit, GR; Pettit, RK; Toki, B; Verdier-Pinard, P | 1 |
| Barr, KJ; Credo, RB; Frost, D; Gehrke, L; Gwaltney, SL; Imade, HM; Kovar, P; Lee, JY; Li, Q; Ng, SC; Nukkala, MA; Sham, HL; Wang, J; Warner, RB; Zielinski, NA | 1 |
| Ducki, S; Lawrence, NJ; Mackenzie, G; Snyder, JP | 1 |
| Chang, CY; Chang, JY; Chen, CM; Kuo, CC; Liou, JP; Yang, MF | 1 |
| Alvarez, R; Mateo, C; Medarde, M; Peláez, R; Pérez-Melero, C | 1 |
8 other study(ies) available for 1-(4-methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)ethene and fosbretabulin
| Article | Year |
|---|---|
Synthesis and evaluation of stilbene and dihydrostilbene derivatives as potential anticancer agents that inhibit tubulin polymerization.
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Chemical Phenomena; Chemistry; Colchicine; Colonic Neoplasms; Humans; Lung Neoplasms; Melanoma; Molecular Structure; Polymers; Stilbenes; Structure-Activity Relationship; Tubulin; Tubulin Modulators; Tumor Cells, Cultured | 1991 |
A Ramberg-Bäcklund route to the stilbenoid anti-cancer agents combretastatin A-4 and DMU-212.
Topics: Antineoplastic Agents; Molecular Structure; Stilbenes; Sulfones | 2007 |
Synthesis and evaluation of analogues of (Z)-1-(4-methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)ethene as potential cytotoxic and antimitotic agents.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Division; Colonic Neoplasms; Humans; Lung Neoplasms; Melanoma; Stilbenes; Structure-Activity Relationship; Tubulin; Tubulin Modulators; Tumor Cells, Cultured | 1992 |
Antineoplastic agents. 379. Synthesis of phenstatin phosphate.
Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents, Phytogenic; Benzophenones; Cattle; Cell Division; Colchicine; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Humans; Leukemia P388; Macromolecular Substances; Molecular Structure; Neisseria gonorrhoeae; Organophosphates; Prodrugs; Protein Binding; Tubulin; Tumor Cells, Cultured | 1998 |
Novel sulfonate analogues of combretastatin A-4: potent antimitotic agents.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Binding, Competitive; Cell Division; Colchicine; Humans; Polymers; Stilbenes; Tubulin; Tubulin Modulators; Tumor Cells, Cultured | 2001 |
Quantitative structure-activity relationship (5D-QSAR) study of combretastatin-like analogues as inhibitors of tubulin assembly.
Topics: Antineoplastic Agents; Bibenzyls; Binding Sites; Colchicine; Ligands; Models, Molecular; Molecular Conformation; Monte Carlo Method; Quantitative Structure-Activity Relationship; Stilbenes; Tubulin; Tubulin Modulators | 2005 |
2-amino and 2'-aminocombretastatin derivatives as potent antimitotic agents.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Colchicine; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Stilbenes; Structure-Activity Relationship; Tubulin Modulators | 2006 |
Conformationally restricted macrocyclic analogues of combretastatins.
Topics: Bibenzyls; Macrocyclic Compounds; Models, Molecular; Molecular Conformation; Stilbenes; Structure-Activity Relationship; Tubulin; Tubulin Modulators | 2007 |