Page last updated: 2024-09-03

1-(4-methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)ethene and colchicine

1-(4-methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)ethene has been researched along with colchicine in 3 studies

Compound Research Comparison

Studies
(1-(4-methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)ethene)
Trials
(1-(4-methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)ethene)
Recent Studies (post-2010)
(1-(4-methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)ethene)
Studies
(colchicine)
Trials
(colchicine)
Recent Studies (post-2010) (colchicine)
3002315,4724042,974
110215,4724042,974

Protein Interaction Comparison

ProteinTaxonomy1-(4-methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)ethene (IC50)colchicine (IC50)
Tubulin alpha-1A chainSus scrofa (pig)3.7639
Tubulin beta chainSus scrofa (pig)3.8663
Tubulin beta-4A chainHomo sapiens (human)2.4334
Tubulin beta chainHomo sapiens (human)2.7244
Tubulin alpha-3C chainHomo sapiens (human)2.4334
Serine/threonine-protein kinase pim-1Homo sapiens (human)4.3
Tubulin alpha-1B chainHomo sapiens (human)2.4334
Tubulin alpha-4A chainHomo sapiens (human)2.4334
Tubulin beta-4B chainHomo sapiens (human)2.4334
Vesicular acetylcholine transporterTetronarce californica (Pacific electric ray)2.62
Tubulin beta-3 chainHomo sapiens (human)2.4334
Tubulin beta-2A chainHomo sapiens (human)2.4334
Tubulin beta-8 chainHomo sapiens (human)2.4334
Tubulin beta-2B chainBos taurus (cattle)2.8255
Tubulin alpha-3E chainHomo sapiens (human)2.4334
Tubulin alpha-1A chainHomo sapiens (human)2.4334
Similar to alpha-tubulin isoform 1 Bos taurus (cattle)3.0611
Similar to alpha-tubulin isoform 1 Bos taurus (cattle)3.1553
Tubulin alpha-1C chainHomo sapiens (human)2.4334
Tubulin beta-6 chainHomo sapiens (human)2.4334
Tubulin beta-2B chainHomo sapiens (human)2.4334
Tubulin beta-1 chainHomo sapiens (human)2.4334

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chakraborti, AK; Cushman, M; Gopal, D; Hamel, E; Lin, CM; Nagarathnam, D1
Crooks, PA; Penthala, NR; Thakkar, S1
Chang, CY; Chang, JY; Chen, CM; Kuo, CC; Liou, JP; Yang, MF1

Other Studies

3 other study(ies) available for 1-(4-methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)ethene and colchicine

ArticleYear
Synthesis and evaluation of stilbene and dihydrostilbene derivatives as potential anticancer agents that inhibit tubulin polymerization.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:8

    Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Chemical Phenomena; Chemistry; Colchicine; Colonic Neoplasms; Humans; Lung Neoplasms; Melanoma; Molecular Structure; Polymers; Stilbenes; Structure-Activity Relationship; Tubulin; Tubulin Modulators; Tumor Cells, Cultured

1991
Heteroaromatic analogs of the resveratrol analog DMU-212 as potent anti-cancer agents.
    Bioorganic & medicinal chemistry letters, 2015, Jul-15, Volume: 25, Issue:14

    Topics: Antineoplastic Agents; Benzofurans; Benzothiazoles; Binding Sites; Cell Line, Tumor; Cell Survival; Colchicine; Drug Screening Assays, Antitumor; Humans; Molecular Docking Simulation; Protein Structure, Tertiary; Resveratrol; Stilbenes; Thiophenes; Tubulin

2015
2-amino and 2'-aminocombretastatin derivatives as potent antimitotic agents.
    Journal of medicinal chemistry, 2006, Oct-19, Volume: 49, Issue:21

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Colchicine; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Stilbenes; Structure-Activity Relationship; Tubulin Modulators

2006