Compounds > 1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane
Page last updated: 2024-09-03

1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane and pregnanolone

1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane has been researched along with pregnanolone in 2 studies

Compound Research Comparison

Studies
(1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane)		Trials
(1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane)		Recent Studies (post-2010)
(1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane)		Studies
(pregnanolone)		Trials
(pregnanolone)		Recent Studies (post-2010) (pregnanolone)
40051,984111666

Protein Interaction Comparison

ProteinTaxonomy1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane (IC50)pregnanolone (IC50)
Gamma-aminobutyric acid receptor subunit piRattus norvegicus (Norway rat)0.101
Gamma-aminobutyric acid receptor subunit beta-1Rattus norvegicus (Norway rat)0.101
Gamma-aminobutyric acid receptor subunit deltaRattus norvegicus (Norway rat)0.101
Gamma-aminobutyric acid receptor subunit gamma-2Rattus norvegicus (Norway rat)0.101
Gamma-aminobutyric acid receptor subunit alpha-5Rattus norvegicus (Norway rat)0.101
Gamma-aminobutyric acid receptor subunit alpha-3Rattus norvegicus (Norway rat)0.101
Gamma-aminobutyric acid receptor subunit gamma-1Rattus norvegicus (Norway rat)0.101
Gamma-aminobutyric acid receptor subunit alpha-2Rattus norvegicus (Norway rat)0.101
Sodium- and chloride-dependent GABA transporter 1Rattus norvegicus (Norway rat)0.117
Gamma-aminobutyric acid receptor subunit alpha-4Rattus norvegicus (Norway rat)0.101
Gamma-aminobutyric acid receptor subunit gamma-3Rattus norvegicus (Norway rat)0.101
Gamma-aminobutyric acid receptor subunit alpha-6Rattus norvegicus (Norway rat)0.101
Sodium- and chloride-dependent GABA transporter 2Rattus norvegicus (Norway rat)0.117
Sodium- and chloride-dependent GABA transporter 3Rattus norvegicus (Norway rat)0.117
Sodium- and chloride-dependent betaine transporterRattus norvegicus (Norway rat)0.117
Gamma-aminobutyric acid receptor subunit alpha-1Mus musculus (house mouse)0.071
Gamma-aminobutyric acid receptor subunit alpha-1Rattus norvegicus (Norway rat)0.101
Gamma-aminobutyric acid receptor subunit beta-3Rattus norvegicus (Norway rat)0.101
Gamma-aminobutyric acid receptor subunit beta-2Rattus norvegicus (Norway rat)0.101
GABA theta subunitRattus norvegicus (Norway rat)0.101
Gamma-aminobutyric acid receptor subunit epsilonRattus norvegicus (Norway rat)0.101

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bíró, T; Maksay, G1
Fodor, L; Maksay, G1

Other Studies

2 other study(ies) available for 1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane and pregnanolone

ArticleYear
High affinity, heterogeneous displacement of [3H]EBOB binding to cerebellar GABA A receptors by neurosteroids and GABA agonists.
    Neuropharmacology, 2005, Volume: 49, Issue:4

    Topics: Animals; Anti-Anxiety Agents; Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic; Cerebellum; Desoxycorticosterone; Dose-Response Relationship, Drug; Drug Interactions; GABA Agonists; gamma-Aminobutyric Acid; Hippocampus; Male; Pregnanolone; Protein Binding; Radioligand Assay; Rats; Rats, Wistar; Receptors, GABA-A

2005
Differential effects of two major neurosteroids on cerebellar and cortical GABA(A) receptor binding and function.
    European journal of pharmacology, 2011, Jan-10, Volume: 650, Issue:1

    Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Cerebellum; Cerebral Cortex; Desoxycorticosterone; Dose-Response Relationship, Drug; Drug Synergism; Furosemide; GABA-A Receptor Agonists; Gene Knockout Techniques; Male; Mice; Neurotransmitter Agents; Pregnanolone; Protein Binding; Rats; Receptors, GABA-A

2011