1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane has been researched along with gamma-aminobutyric acid in 17 studies
*gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system. [MeSH]
*gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system. [MeSH]
| Studies (1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane) | Trials (1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane) | Recent Studies (post-2010) (1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane) | Studies (gamma-aminobutyric acid) | Trials (gamma-aminobutyric acid) | Recent Studies (post-2010) (gamma-aminobutyric acid) |
|---|---|---|---|---|---|
| 40 | 0 | 5 | 40,215 | 1,423 | 9,631 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (41.18) | 18.2507 |
| 2000's | 9 (52.94) | 29.6817 |
| 2010's | 1 (5.88) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Casida, JE; Cole, LM; Roush, RT | 1 |
| Casida, JE; Hainzl, D | 1 |
| Casida, JE; Huang, J | 1 |
| Chiu, TH; Li, M; Rosenberg, HC; Zhao, TJ | 1 |
| Korpi, ER; Maksay, G; Uusi-Oukari, M | 1 |
| Lees, G; Nicholson, RA; Verdon, B; Zheng, J | 1 |
| Honda, H; Ikeda, T; Nagata, K; Narahashi, T; Okuyama, E; Ozoe, Y; Shono, T | 1 |
| Casida, JE; Höld, KM; Ikeda, T; Narahashi, T; Sirisoma, NS | 1 |
| Kisara, K; Ohashi, K; Ohta, T; Oshima, Y; Sakakibara, R; Shibusawa, K; Tadano, T; Takaya, Y; Uwai, K | 1 |
| Casida, JE; Kamita, SG; Ratra, GS | 1 |
| Casida, JE; Erkkila, BE; Ratra, GS; Weiss, DS | 1 |
| Coyne, L; Lees, G; Neufield, KD; Nicholson, RA; Zheng, J | 1 |
| Bíró, T; Maksay, G | 1 |
| Ihara, M; Ishida, C; Matsuda, K; Okuda, H; Ozoe, Y | 1 |
| Maksay, G; Uusi-Oukari, M | 1 |
| Casida, JE; Chen, L; Giacomini, KM; Xue, L | 1 |
| Mehta, AK; Ticku, MK | 1 |
17 other study(ies) available for 1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane and gamma-aminobutyric acid
| Article | Year |
|---|---|
Drosophila GABA-gated chloride channel: modified [3H]EBOB binding site associated with Ala-->Ser or Gly mutants of Rdl subunit.
Topics: Alanine; Animals; Binding Sites; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chloride Channels; Drosophila melanogaster; Drosophila Proteins; gamma-Aminobutyric Acid; Glycine; Insecticide Resistance; Ion Channel Gating; Muscimol; Mutation; Receptors, GABA-A; Serine; Structure-Activity Relationship; Tritium | 1995 |
Fipronil insecticide: novel photochemical desulfinylation with retention of neurotoxicity.
Topics: Animals; Brain; Bridged Bicyclo Compounds, Heterocyclic; Chloride Channels; Crystallography, X-Ray; Enzyme Inhibitors; Female; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Houseflies; Insecticides; Ion Channel Gating; Lethal Dose 50; Magnetic Resonance Spectroscopy; Male; Mice; Molecular Conformation; Neurotoxins; Photochemistry; Pyrazoles | 1996 |
Characterization of [3H]ethynylbicycloorthobenzoate ([3H]EBOB) binding and the action of insecticides on the gamma-aminobutyric acid-gated chloride channel in cultured cerebellar granule neurons.
Topics: Animals; Binding Sites; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Cerebellum; Chloride Channels; Cytoplasmic Granules; gamma-Aminobutyric Acid; Insecticides; Ion Channel Gating; Neurons; Protein Binding; Radioligand Assay; Rats; Rats, Sprague-Dawley; Tritium | 1996 |
Decreased benzodiazepine binding with little effect on gamma-aminobutyric acid binding in rat brain after treatment with antisense oligodeoxynucleotide to the gamma-aminobutyric acidA receptor gamma-2 subunit.
Topics: Animals; Base Sequence; Benzodiazepines; Blotting, Western; Bridged Bicyclo Compounds, Heterocyclic; Cerebellum; Flunitrazepam; gamma-Aminobutyric Acid; Male; Muscimol; Oligonucleotides, Antisense; Protein Binding; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Tritium; Xanthines | 1998 |
Bimodal action of furosemide on convulsant [3H]EBOB binding to cerebellar and cortical GABA(A) receptors.
Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Cerebellum; Cerebral Cortex; Chlorides; Convulsants; Furosemide; GABA Modulators; gamma-Aminobutyric Acid; Kinetics; Niflumic Acid; Pentobarbital; Rats; Rats, Wistar; Receptors, GABA-A | 1998 |
Inhibition of GABA-gated chloride channels by 12,14-dichlorodehydroabietic acid in mammalian brain.
Topics: Abietanes; Amphotericin B; Animals; Binding Sites; Brain; Bridged Bicyclo Compounds, Heterocyclic; Chloride Channels; Chlorides; Diterpenes; Drug Interactions; gamma-Aminobutyric Acid; Male; Mice; Phenanthrenes; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Sesterterpenes; Tetrodotoxin | 1999 |
Anisatin modulation of the gamma-aminobutyric acid receptor-channel in rat dorsal root ganglion neurons.
Topics: Affinity Labels; Animals; Animals, Newborn; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Electric Stimulation; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Ganglia, Spinal; Insecticides; Kinetics; Lactones; Membrane Potentials; Neurons; Patch-Clamp Techniques; Picrotoxin; Plants; Rats; Receptors, GABA; Sesquiterpenes; Sesterterpenes; Spiro Compounds | 1999 |
Alpha-thujone (the active component of absinthe): gamma-aminobutyric acid type A receptor modulation and metabolic detoxification.
Topics: Absinthe; Animals; Bicyclic Monoterpenes; Brain; Bridged Bicyclo Compounds, Heterocyclic; Chloride Channels; Convulsants; Dieldrin; Drosophila; Ethanol; GABA Modulators; gamma-Aminobutyric Acid; Inactivation, Metabolic; Insecticide Resistance; Ion Channel Gating; Male; Mice; Microsomes, Liver; Monoterpenes; Rabbits; Rats; Receptors, GABA; Terpenes | 2000 |
Exploring the structural basis of neurotoxicity in C(17)-polyacetylenes isolated from water hemlock.
Topics: Acetylene; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chloride Channels; GABA Antagonists; gamma-Aminobutyric Acid; Hemlock; In Vitro Techniques; Ion Channel Gating; Lethal Dose 50; Male; Mice; Plants, Toxic; Radioligand Assay; Rats; Receptors, GABA-A; Structure-Activity Relationship; Toxicity Tests, Acute | 2000 |
Role of human GABA(A) receptor beta3 subunit in insecticide toxicity.
Topics: Binding Sites; Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic; Convulsants; Endosulfan; gamma-Aminobutyric Acid; Genes; Hexachlorocyclohexane; Humans; Insecticides; Muscimol; Protein Subunits; Pyrazoles; Receptors, GABA-A; Recombinant Proteins; Structure-Activity Relationship; Transfection; Tritium | 2001 |
Unique insecticide specificity of human homomeric rho 1 GABA(C) receptor.
Topics: Binding Sites; Bridged Bicyclo Compounds, Heterocyclic; Chloride Channels; gamma-Aminobutyric Acid; Humans; Insecticides; Membrane Potentials; Receptors, GABA; Receptors, GABA-A; Sensitivity and Specificity | 2002 |
The sleep hormone oleamide modulates inhibitory ionotropic receptors in mammalian CNS in vitro.
Topics: Animals; Biological Transport, Active; Brain; Bridged Bicyclo Compounds, Heterocyclic; Chloride Channels; Female; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glycine; Humans; Hypnotics and Sedatives; Male; Mice; Muscimol; Oleic Acids; Oocytes; Radioligand Assay; Receptors, GABA-A; Receptors, Glycine; Sleep; Synaptic Membranes; Tritium; Xenopus laevis | 2002 |
High affinity, heterogeneous displacement of [3H]EBOB binding to cerebellar GABA A receptors by neurosteroids and GABA agonists.
Topics: Animals; Anti-Anxiety Agents; Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic; Cerebellum; Desoxycorticosterone; Dose-Response Relationship, Drug; Drug Interactions; GABA Agonists; gamma-Aminobutyric Acid; Hippocampus; Male; Pregnanolone; Protein Binding; Radioligand Assay; Rats; Rats, Wistar; Receptors, GABA-A | 2005 |
Differential blocking actions of 4'-ethynyl-4-n-propylbicycloorthobenzoate (EBOB) and gamma-hexachlorocyclohexane (gamma-HCH) on gamma-aminobutyric acid- and glutamate-induced responses of American cockroach neurons.
Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Chloride Channels; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamic Acid; Hexachlorocyclohexane; Insecticides; Neurons; Patch-Clamp Techniques; Periplaneta; Receptors, GABA; Receptors, Glutamate | 2005 |
Allosteric modulation of [3H]EBOB binding to GABAA receptors by diflunisal analogues.
Topics: Affinity Labels; Allosteric Regulation; Animals; Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Binding, Competitive; Biphenyl Compounds; Bridged Bicyclo Compounds, Heterocyclic; Diflunisal; gamma-Aminobutyric Acid; Hydroxyl Radical; Male; Meclofenamic Acid; Molecular Conformation; Molecular Structure; Prosencephalon; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Synaptic Transmission | 2006 |
GABAA receptor open-state conformation determines non-competitive antagonist binding.
Topics: Anesthetics, General; Animals; Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic; Dose-Response Relationship, Drug; Etomidate; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Humans; Mutagenesis, Site-Directed; Mutation; Protein Conformation; Protein Subunits; Radioligand Assay; Receptors, GABA-A; Recombinant Fusion Proteins | 2011 |
Characterization of the picrotoxin site of GABAA receptors.
Topics: Animals; Binding Sites; Binding, Competitive; Brain Chemistry; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; gamma-Aminobutyric Acid; Kinetics; Membranes; Nitriles; Picrotoxin; Radioligand Assay; Rats; Receptors, GABA-A; Specimen Handling; Statistics as Topic; Sulfur Radioisotopes | 2001 |