Page last updated: 2024-09-03

1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane and furosemide

1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane has been researched along with furosemide in 2 studies

Compound Research Comparison

Studies
(1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane)
Trials
(1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane)
Recent Studies (post-2010)
(1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane)
Studies
(furosemide)
Trials
(furosemide)
Recent Studies (post-2010) (furosemide)
400513,6311,3582,486

Protein Interaction Comparison

ProteinTaxonomy1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane (IC50)furosemide (IC50)
Corticosteroid 11-beta-dehydrogenase isozyme 1Homo sapiens (human)3.76
Corticosteroid 11-beta-dehydrogenase isozyme 1Mus musculus (house mouse)3.76
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)3.2

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Korpi, ER; Maksay, G; Uusi-Oukari, M1
Fodor, L; Maksay, G1

Other Studies

2 other study(ies) available for 1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane and furosemide

ArticleYear
Bimodal action of furosemide on convulsant [3H]EBOB binding to cerebellar and cortical GABA(A) receptors.
    Neurochemistry international, 1998, Volume: 33, Issue:4

    Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Cerebellum; Cerebral Cortex; Chlorides; Convulsants; Furosemide; GABA Modulators; gamma-Aminobutyric Acid; Kinetics; Niflumic Acid; Pentobarbital; Rats; Rats, Wistar; Receptors, GABA-A

1998
Differential effects of two major neurosteroids on cerebellar and cortical GABA(A) receptor binding and function.
    European journal of pharmacology, 2011, Jan-10, Volume: 650, Issue:1

    Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Cerebellum; Cerebral Cortex; Desoxycorticosterone; Dose-Response Relationship, Drug; Drug Synergism; Furosemide; GABA-A Receptor Agonists; Gene Knockout Techniques; Male; Mice; Neurotransmitter Agents; Pregnanolone; Protein Binding; Rats; Receptors, GABA-A

2011