Compounds > 1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane
Page last updated: 2024-09-03

1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane and etomidate

1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane has been researched along with etomidate in 1 studies

Compound Research Comparison

Studies
(1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane)		Trials
(1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane)		Recent Studies (post-2010)
(1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane)		Studies
(etomidate)		Trials
(etomidate)		Recent Studies (post-2010) (etomidate)
40052,071401576

Protein Interaction Comparison

ProteinTaxonomy1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane (IC50)etomidate (IC50)
Cytochrome P450 11B1, mitochondrialHomo sapiens (human)0.0005
Cytochrome P450 11B2, mitochondrialHomo sapiens (human)0.0009

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Casida, JE; Chen, L; Giacomini, KM; Xue, L1

Other Studies

1 other study(ies) available for 1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane and etomidate

ArticleYear
GABAA receptor open-state conformation determines non-competitive antagonist binding.
    Toxicology and applied pharmacology, 2011, Feb-01, Volume: 250, Issue:3

    Topics: Anesthetics, General; Animals; Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic; Dose-Response Relationship, Drug; Etomidate; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Humans; Mutagenesis, Site-Directed; Mutation; Protein Conformation; Protein Subunits; Radioligand Assay; Receptors, GABA-A; Recombinant Fusion Proteins

2011