1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane and desoxycorticosterone

1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane has been researched along with desoxycorticosterone in 2 studies

Compound Research Comparison

Studies (1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane)	Trials (1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane)	Recent Studies (post-2010) (1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane)	Studies (desoxycorticosterone)	Trials (desoxycorticosterone)	Recent Studies (post-2010) (desoxycorticosterone)
40	0	5	7,588	52	284

Protein Interaction Comparison

Protein	Taxonomy	1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane (IC50)	desoxycorticosterone (IC50)
Solute carrier family 22 member 3	Rattus norvegicus (Norway rat)		8.4
Solute carrier family 22 member 2	Rattus norvegicus (Norway rat)		1.9

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	1 (50.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bíró, T; Maksay, G	1
Fodor, L; Maksay, G	1

Other Studies

2 other study(ies) available for 1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane and desoxycorticosterone

Article	Year
High affinity, heterogeneous displacement of [3H]EBOB binding to cerebellar GABA A receptors by neurosteroids and GABA agonists. Neuropharmacology, 2005, Volume: 49, Issue:4 Topics: Animals; Anti-Anxiety Agents; Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic; Cerebellum; Desoxycorticosterone; Dose-Response Relationship, Drug; Drug Interactions; GABA Agonists; gamma-Aminobutyric Acid; Hippocampus; Male; Pregnanolone; Protein Binding; Radioligand Assay; Rats; Rats, Wistar; Receptors, GABA-A	2005
Differential effects of two major neurosteroids on cerebellar and cortical GABA(A) receptor binding and function. European journal of pharmacology, 2011, Jan-10, Volume: 650, Issue:1 Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Cerebellum; Cerebral Cortex; Desoxycorticosterone; Dose-Response Relationship, Drug; Drug Synergism; Furosemide; GABA-A Receptor Agonists; Gene Knockout Techniques; Male; Mice; Neurotransmitter Agents; Pregnanolone; Protein Binding; Rats; Receptors, GABA-A	2011

Article

Year

High affinity, heterogeneous displacement of [3H]EBOB binding to cerebellar GABA A receptors by neurosteroids and GABA agonists.

Neuropharmacology, 2005, Volume: 49, Issue:4

Topics: Animals; Anti-Anxiety Agents; Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic; Cerebellum; Desoxycorticosterone; Dose-Response Relationship, Drug; Drug Interactions; GABA Agonists; gamma-Aminobutyric Acid; Hippocampus; Male; Pregnanolone; Protein Binding; Radioligand Assay; Rats; Rats, Wistar; Receptors, GABA-A

2005

Differential effects of two major neurosteroids on cerebellar and cortical GABA(A) receptor binding and function.

European journal of pharmacology, 2011, Jan-10, Volume: 650, Issue:1

Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Cerebellum; Cerebral Cortex; Desoxycorticosterone; Dose-Response Relationship, Drug; Drug Synergism; Furosemide; GABA-A Receptor Agonists; Gene Knockout Techniques; Male; Mice; Neurotransmitter Agents; Pregnanolone; Protein Binding; Rats; Receptors, GABA-A

2011