1-(3-trifluoromethylphenyl)piperazine has been researched along with 1-benzylpiperazine in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.45) | 18.7374 |
| 1990's | 1 (3.45) | 18.2507 |
| 2000's | 9 (31.03) | 29.6817 |
| 2010's | 18 (62.07) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| el-Ashmawy, MB; Fischer, JB; Glennon, RA; Herndon, JL; Howie, KJ; Ismaiel, AM; Server, AC; Yousif, MY | 1 |
| Glennon, RA; Lyon, RA; Magee, PS; McKenney, JD; Titeler, M | 1 |
| Cuddy, ML | 1 |
| Kamata, T; Katagi, M; Miki, A; Nakajima, K; Nishikawa, M; Shima, N; Tsuchihashi, H; Tsutsumi, H | 1 |
| Brennan, KA; Fitzmaurice, PS; Johnstone, AC; Kennedy, MA; Lea, RA; Schenk, S | 1 |
| Elliott, S; Smith, C | 1 |
| Lecompte, Y; Perrin, M; Roussel, O | 1 |
| Button, J; Dargan, PI; Holt, DW; Lidder, S; Ramsey, J; Wood, DM | 1 |
| Aldington, S; Beasley, R; Caldwell, B; Dickson, S; Lucas, N; McDowall, J; Robinson, G; Thompson, I; Weatherall, M; Williams, G | 1 |
| Sweetsur, P; Wilkins, C | 1 |
| Girling, M; Sweetsur, P; Wilkins, C | 1 |
| Antia, U; Russell, BR; Tingle, MD | 3 |
| Jan, RK; Jensen, MA; Kydd, RR; Lee, H; Lin, JC; Russell, BR | 1 |
| Nawrocka, K; Sommerfeld, K; Łukasik-Głebock, M | 1 |
| Ikeda, R; Kikura-Hanajiri, R; Kuroda, N; Nakashima, K; Wada, M; Yamahara, K | 1 |
| Beasley, DM; Gee, P; Schep, LJ; Slaughter, RJ; Vale, JA | 1 |
| Jan, RK; Kydd, RR; Lin, JC; Russell, BR | 1 |
| Baron, M; Elie, L; Elie, M | 1 |
| Chung, KH; Kim, HR; Kim, MJ; Lee, SY; Min, CR; Oh, SM; Park, YJ | 1 |
| Botch-Jones, SR; Johnson, RD | 1 |
| Curley, LE; Kirk, IJ; Kydd, RR; Russell, BR | 1 |
| Antia, U; Fredatovich, JD; Na, Y; Neale, PT; Roberts, AF; Russell, B; Thrimawithana, TR; Young, SA; Zhou, H | 1 |
| Curley, LE; Kirk, IJ; Kydd, RR; Lee, H; McNair, N; Pillai, A; Robertson, MC; Russell, BR | 1 |
| Curley, LE; Kirk, IJ; Kydd, RR; Lee, H; Russell, BR; Sollers, JJ; Wang, GY | 1 |
| Arbo, MD; Cadenas, C; Carmo, H; de Lourdes Bastos, M; Godoy, P; Hengstler, JG; Melega, S; Rahnenführer, J; Reif, R; Rempel, E; Schug, M; Stöber, R | 1 |
| Curley, LE; Kirk, IJ; Kydd, RR; Lee, H; Russell, BR; Wang, GY | 1 |
| Bastos, ML; Carmo, H; Carvalho, F; Dias da Silva, D; Martins, MJ; Moreira, P; Silva, MJ; Valente, MJ | 1 |
5 review(s) available for 1-(3-trifluoromethylphenyl)piperazine and 1-benzylpiperazine
| Article | Year |
|---|---|
Common drugs of abuse--Part II.
Topics: 4-Butyrolactone; Catha; Designer Drugs; Dibenzothiazepines; Diterpenes; Diterpenes, Clerodane; DOM 2,5-Dimethoxy-4-Methylamphetamine; Drug and Narcotic Control; Flunitrazepam; Hallucinogens; Humans; Illicit Drugs; Ketamine; Lysergic Acid Diethylamide; Methamphetamine; Motivation; N-Methyl-3,4-methylenedioxyamphetamine; Phencyclidine; Phenylpropanolamine; Piperazines; Psilocybin; Quetiapine Fumarate; Sodium Oxybate; Substance-Related Disorders; United States | 2004 |
Benzylpiperazine: a drug of abuse?
Topics: Animals; Behavior, Animal; Drug and Narcotic Control; Humans; Illicit Drugs; Piperazines | 2007 |
[1-benzylpiperazine (BZP) and 1-(3-trifluorométhylphényl)pipérazine (TFMPP): emergence of two agents which lead to misuse].
Topics: France; Humans; Illicit Drugs; Piperazines; Serotonin Receptor Agonists; Substance-Related Disorders | 2008 |
The clinical toxicology of the designer "party pills" benzylpiperazine and trifluoromethylphenylpiperazine.
Topics: Designer Drugs; Fever; Humans; Illicit Drugs; Piperazines; Seizures; Serotonin Receptor Agonists; Substance Abuse Detection; Substance-Related Disorders | 2011 |
Subjective effects in humans following administration of party pill drugs BZP and TFMPP alone and in combination.
Topics: Affect; Anxiety; Central Nervous System Stimulants; Humans; Illicit Drugs; Piperazines | 2011 |
5 trial(s) available for 1-(3-trifluoromethylphenyl)piperazine and 1-benzylpiperazine
| Article | Year |
|---|---|
Randomised double-blind, placebo-controlled trial of the effects of the 'party pills' BZP/TFMPP alone and in combination with alcohol.
Topics: Adult; Akathisia, Drug-Induced; Alcohol Drinking; Anxiety; Central Nervous System Stimulants; Cross-Over Studies; Double-Blind Method; Drug Combinations; Early Termination of Clinical Trials; Female; Hallucinations; Humans; Male; Migraine Disorders; New Zealand; Nonprescription Drugs; Outpatient Clinics, Hospital; Piperazines; Psychotropic Drugs; Sleep Initiation and Maintenance Disorders; Somatosensory Disorders; Young Adult | 2010 |
Determining the subjective and physiological effects of BZP combined with TFMPP in human males.
Topics: Adolescent; Adult; Affect; Analysis of Variance; Blood Pressure; Body Temperature; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Heart Rate; Humans; Illicit Drugs; Male; New Zealand; Pain Measurement; Physiological Phenomena; Piperazines; Psychiatric Status Rating Scales; Young Adult | 2011 |
Differential responses to anticipation of reward after an acute dose of the designer drugs benzylpiperazine (BZP) and trifluoromethylphenylpiperazine (TFMPP) alone and in combination using functional magnetic resonance imaging (fMRI).
Topics: Adolescent; Adult; Brain; Cross-Over Studies; Designer Drugs; Dopamine; Dose-Response Relationship, Drug; Double-Blind Method; Female; Gambling; Humans; Magnetic Resonance Imaging; Male; Piperazines; Reward; Serotonin; Young Adult | 2013 |
Acute effects of BZP, TFMPP and the combination of BZP and TFMPP in comparison to dexamphetamine on an auditory oddball task using electroencephalography: a single-dose study.
Topics: Adolescent; Adult; Central Nervous System Stimulants; Designer Drugs; Dextroamphetamine; Discrimination, Psychological; Dopamine; Double-Blind Method; Drug Synergism; Electroencephalography; Event-Related Potentials, P300; Humans; Male; Piperazines; Psychomotor Performance; Reaction Time; Serotonin; Young Adult | 2016 |
Investigation of the effects of 'piperazine-containing party pills' and dexamphetamine on interhemispheric communication using electroencephalography.
Topics: Adolescent; Adult; Dextroamphetamine; Dopamine Uptake Inhibitors; Double-Blind Method; Electroencephalography; Evoked Potentials, Visual; Functional Laterality; Humans; Male; Neural Pathways; Piperazines; Reaction Time; Serotonin Receptor Agonists; Young Adult | 2016 |
19 other study(ies) available for 1-(3-trifluoromethylphenyl)piperazine and 1-benzylpiperazine
| Article | Year |
|---|---|
Novel 1-phenylpiperazine and 4-phenylpiperidine derivatives as high-affinity sigma ligands.
Topics: Animals; Guinea Pigs; In Vitro Techniques; Ligands; Piperazines; Piperidines; Radioligand Assay; Receptors, Dopamine; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Phencyclidine; Receptors, sigma; Structure-Activity Relationship | 1991 |
Synthesis and evaluation of phenyl- and benzoylpiperazines as potential serotonergic agents.
Topics: Animals; Computers; Kinetics; Magnetic Resonance Spectroscopy; Models, Molecular; Piperazines; Rats; Receptors, Serotonin; Serotonin | 1986 |
Development of simultaneous gas chromatography-mass spectrometric and liquid chromatography-electrospray ionization mass spectrometric determination method for the new designer drugs, N-benzylpiperazine (BZP), 1-(3-trifluoromethylphenyl)piperazine (TFMPP)
Topics: Animals; Chromatography, Liquid; Designer Drugs; Gas Chromatography-Mass Spectrometry; Piperazines; Rats; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Substance Abuse Detection | 2005 |
Investigation of the first deaths in the United Kingdom involving the detection and quantitation of the piperazines BZP and 3-TFMPP.
Topics: Adolescent; Adult; Cause of Death; Chromatography, High Pressure Liquid; Humans; Male; Piperazines; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Substance Abuse Detection; Substance-Related Disorders; United Kingdom | 2008 |
Dissociative and sympathomimetic toxicity associated with recreational use of 1-(3-trifluoromethylphenyl) piperazine (TFMPP) and 1-benzylpiperzine (BZP).
Topics: Adolescent; Bruxism; Dissociative Disorders; Electrocardiography; Gas Chromatography-Mass Spectrometry; Hallucinogens; Humans; Illicit Drugs; Male; N-Methyl-3,4-methylenedioxyamphetamine; Piperazines; Pupil; Substance-Related Disorders; Sympathomimetics; Tachycardia; Young Adult | 2008 |
Differences in harm from legal BZP/TFMPP party pills between North Island and South Island users in New Zealand: a case of effective industry self-regulation?
Topics: Adolescent; Adult; Alcohol Drinking; Drug and Narcotic Control; Drug Industry; Female; Harm Reduction; Health Surveys; Humans; Male; Middle Aged; New Zealand; Off-Label Use; Piperazines; Young Adult | 2010 |
Patterns of benzylpiperazine/trifluoromethylphenylpiperazine party pill use and adverse effects in a population sample in New Zealand.
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Central Nervous System Stimulants; Drug Combinations; Female; Humans; Illicit Drugs; Male; New Zealand; Piperazines; Serotonin Receptor Agonists; Sex Factors; Substance-Related Disorders; Young Adult | 2008 |
Metabolic interactions with piperazine-based 'party pill' drugs.
Topics: Adult; Aged; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Designer Drugs; Drug Interactions; Female; Humans; In Vitro Techniques; Isoenzymes; Male; Microsomes, Liver; Middle Aged; Piperazines | 2009 |
In vivo interactions between BZP and TFMPP (party pill drugs).
Topics: Administration, Oral; Adult; Drug Interactions; Follow-Up Studies; Humans; Illicit Drugs; Male; New Zealand; Piperazines; Prevalence; Reference Values; Serotonin Receptor Agonists; Spectrometry, Mass, Electrospray Ionization; Substance-Related Disorders; Young Adult | 2009 |
Validation of an LC-MS method for the detection and quantification of BZP and TFMPP and their hydroxylated metabolites in human plasma and its application to the pharmacokinetic study of TFMPP in humans.
Topics: Adolescent; Adult; Chromatography, Liquid; Female; Forensic Toxicology; Humans; Illicit Drugs; Male; Mass Spectrometry; Piperazine; Piperazines; Specimen Handling; Young Adult | 2010 |
Legal highs toxicity--symptomatology and clinical diagnosis in case series.
Topics: Adult; Female; Humans; Male; Piperazines; Psychotropic Drugs; Substance Abuse Detection; Substance-Related Disorders | 2010 |
Simultaneous determination of N-benzylpiperazine and 1-(3-trifluoromethylphenyl)piperazine in rat plasma by HPLC-fluorescence detection and its application to monitoring of these drugs.
Topics: Animals; Benzoates; Chromatography, High Pressure Liquid; Drug Monitoring; Imidazoles; Limit of Detection; Male; Piperazines; Rats; Rats, Wistar; Reproducibility of Results; Spectrometry, Fluorescence | 2012 |
An analysis of legal highs: do they contain what it says on the tin?
Topics: Caffeine; Gas Chromatography-Mass Spectrometry; Humans; Illicit Drugs; Indans; Internet; Piperazines; Spectroscopy, Fourier Transform Infrared | 2011 |
Estrogenic effects and their action mechanism of the major active components of party pill drugs.
Topics: Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Drug Antagonism; Estrogen Receptor Modulators; Estrogens; Female; Gene Expression; Gene Expression Regulation; Genes, Reporter; Humans; Illicit Drugs; Organ Size; Piperazines; Serotonin Receptor Agonists; Tamoxifen; Uterus | 2012 |
The stability of four designer drugs: MDPV, mephedrone, BZP and TFMPP in three biological matrices under various storage conditions.
Topics: Benzodioxoles; Cold Temperature; Designer Drugs; Drug Stability; Drug Storage; Humans; Methamphetamine; Piperazines; Pyrrolidines; Refrigeration; Synthetic Cathinone | 2013 |
Pharmaceutical quality of "party pills" raises additional safety concerns in the use of illicit recreational drugs.
Topics: Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Drug Labeling; Illicit Drugs; New Zealand; Piperazines; Safety | 2013 |
Acute effects of the designer drugs benzylpiperazine (BZP) and trifluoromethylphenylpiperazine (TFMPP) using functional magnetic resonance imaging (fMRI) and the Stroop task--a pilot study.
Topics: Adolescent; Adult; Attention; Brain; Cross-Over Studies; Designer Drugs; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Magnetic Resonance Imaging; Male; Pilot Projects; Piperazines; Stroop Test; Young Adult | 2015 |
Hepatotoxicity of piperazine designer drugs: up-regulation of key enzymes of cholesterol and lipid biosynthesis.
Topics: Animals; Cell Survival; Cells, Cultured; Chemical and Drug Induced Liver Injury; Cholesterol; Designer Drugs; Enzyme Induction; Gene Expression Profiling; Hepatocytes; Inhibitory Concentration 50; Lipid Metabolism; Male; Oligonucleotide Array Sequence Analysis; Osmolar Concentration; Piperazines; Principal Component Analysis; Rats, Wistar | 2016 |
In vitro hepatotoxicity of 'Legal X': the combination of 1-benzylpiperazine (BZP) and 1-(m-trifluoromethylphenyl)piperazine (TFMPP) triggers oxidative stress, mitochondrial impairment and apoptosis.
Topics: Animals; Apoptosis; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Energy Metabolism; Hepatocytes; Humans; Male; Mitochondria; Oxidative Stress; Piperazines; Rats, Wistar; Species Specificity | 2017 |