1-(3-chlorophenyl)piperazine has been researched along with quipazine in 40 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (45.00) | 18.7374 |
| 1990's | 15 (37.50) | 18.2507 |
| 2000's | 7 (17.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Glennon, RA | 2 |
| Audia, JE; Baez, M; Cohen, ML; Kursar, JD; Lucaites, VL; Nelson, DL; Nissen, JS; Schenck, KW; Wainscott, DB | 1 |
| Abdel-Rahman, AA; Dukat, M; Glennon, RA; Gyermek, L; Ingher, S; Ismaiel, AM; Teitler, M | 1 |
| Conklin, DS; Fitzgerald, LW; Hartig, PR; Iyer, G; Kostich, WA; Krause, CM; Largent, BL; Marshall, AP; Patterson, JP; Tran, DP | 1 |
| Dupre, A; Egan, C; Grinde, E; Hake, M; Herrick-Davis, K; Roth, BL; Teitler, M | 1 |
| Benwell, K; Bickerdike, M; Kennett, G; Knight, AR; Misra, A; Quirk, K; Revell, D | 1 |
| Cleves, AE; Jain, AN; Kirshner, D; Langham, JJ; Spitzer, R | 1 |
| Eide, PK | 1 |
| Freo, U; Greig, NH; Holloway, HW; Soncrant, TT | 1 |
| Freo, U; Larson, DM; Rapoport, SI; Soncrant, TT; Tolliver, T | 1 |
| Bloomquist, W; Cohen, ML; Robertson, DW; Wong, DT | 1 |
| Cloëz, I; Fillion, G; Harel-Dupas, C | 1 |
| McKearney, JW | 2 |
| Bendotti, C; Garattini, S; Invernizzi, R; Mennini, T; Samanin, R | 1 |
| Cooper, SJ; Neill, JC | 1 |
| Jenner, P; Marsden, CD; Stewart, BR | 1 |
| Barrett, JE; Brady, LS | 1 |
| Clineschmidt, BV; Pettibone, DJ; Reiss, DR; Robinson, JL | 1 |
| Round, A; Wallis, DI | 1 |
| Ireland, SJ; Tyers, MB | 1 |
| Antkiewicz-Michaluk, L; Rokosz-Pelc, A; Vetulani, J | 1 |
| Pawłowski, L | 1 |
| Shelekhov, SL; Val'dman, AV | 2 |
| Bendotti, C; Borroni, E; Borsini, F; Caccia, S; Invernizzi, R; Mennini, T; Pataccini, R; Samanin, R | 1 |
| Cohen, ML; Fuller, RW | 1 |
| Clemens, JA; Roush, ME | 1 |
| Cervo, L; Mennini, T; Poggesi, E; Rochat, C; Samanin, R | 1 |
| Garattini, S; Mennini, T; Samanin, R | 1 |
| Audinot, V; Brocco, M; Gobert, A; Millan, MJ; Schreiber, R; Veiga, S | 1 |
| Jeffrey, JJ; Rydelek-Fitzgerald, L; Teitler, M; Wilcox, BD | 1 |
| Fiorella, D; Helsley, S; Rabin, RA; Winter, JC | 1 |
| Carey, JE; Chen, C; Elliott, JM; Flanigan, TP; Kumar, C; McDonald, B; Newberry, NR; Newton, RA; Phipps, SL | 1 |
| Schechter, MD | 1 |
| Caccia, S; Cervo, L; Fracasso, C; Guiso, G; Nacca, A | 1 |
| Evans, DC; Hemrick-Luecke, SK | 1 |
| Adaikan, PG; Hayes, ES | 1 |
| Guertin, PA; Landry, ES | 1 |
3 review(s) available for 1-(3-chlorophenyl)piperazine and quipazine
| Article | Year |
|---|---|
Central serotonin receptors as targets for drug research.
Topics: Animals; Humans; Receptors, Serotonin; Research Design; Serotonin | 1987 |
Higher-end serotonin receptors: 5-HT(5), 5-HT(6), and 5-HT(7).
Topics: Animals; Humans; Ligands; Receptors, Serotonin; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists | 2003 |
Neurochemical mechanism of action of drugs which modify feeding via the serotoninergic system.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholine; Animals; Appetite; Appetite Depressants; Brain; Brain Chemistry; Dopamine; Endorphins; Feeding Behavior; Fenfluramine; gamma-Aminobutyric Acid; Hydroxyindoleacetic Acid; Neural Pathways; Norepinephrine; Piperazines; Pyridines; Quipazine; Rats; Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes | 1986 |
37 other study(ies) available for 1-(3-chlorophenyl)piperazine and quipazine
| Article | Year |
|---|---|
Pharmacological characteristics of the newly cloned rat 5-hydroxytryptamine2F receptor.
Topics: Animals; Binding Sites; Cell Line; Cloning, Molecular; Gastric Fundus; Inositol 1,4,5-Trisphosphate; Male; Muscle Contraction; Muscle, Smooth; Radioligand Assay; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Temperature | 1993 |
Structure-activity relationships for the binding of arylpiperazines and arylbiguanides at 5-HT3 serotonin receptors.
Topics: Animals; Biguanides; Heart Rate; Male; Molecular Structure; Muscle Contraction; Piperazines; Rabbits; Rats; Receptors, Serotonin; Reflex; Serotonin Antagonists; Serotonin Receptor Agonists; Structure-Activity Relationship; Urinary Bladder | 1996 |
High-affinity agonist binding correlates with efficacy (intrinsic activity) at the human serotonin 5-HT2A and 5-HT2C receptors: evidence favoring the ternary complex and two-state models of agonist action.
Topics: Amphetamines; Binding, Competitive; Cell Line; Ergolines; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Hydrolysis; Isomerism; Ligands; Models, Biological; Phosphatidylinositols; Receptors, Serotonin; Recombinant Proteins; Serotonin Antagonists; Serotonin Receptor Agonists; Spiperone | 1999 |
Agonist high and low affinity state ratios predict drug intrinsic activity and a revised ternary complex mechanism at serotonin 5-HT(2A) and 5-HT(2C) receptors.
Topics: Animals; Cell Line; Computer Simulation; GTP-Binding Proteins; Inositol Phosphates; Kinetics; Phosphatidylinositols; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Recombinant Proteins; Serotonin Receptor Agonists; Signal Transduction; Transfection; Tritium | 2000 |
Pharmacological characterisation of the agonist radioligand binding site of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors.
Topics: Binding Sites; Binding, Competitive; Cell Line; Humans; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Recombinant Proteins; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists | 2004 |
Physical binding pocket induction for affinity prediction.
Topics: Binding Sites; Ligands; Models, Molecular; Neural Networks, Computer; Peptide Fragments; Protein Binding; Receptor, Serotonin, 5-HT1A | 2009 |
Stimulation of 5-HT1 receptors in the spinal cord changes substance P-induced behaviour.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Analgesia; Animals; Indoles; Injections, Spinal; Male; Mice; Mice, Inbred Strains; Nerve Endings; Neurons; Pain; Piperazines; Quipazine; Receptors, Serotonin; Reference Values; Serotonin; Serotonin Antagonists; Spinal Cord; Stereotyped Behavior; Substance P | 1992 |
Chronic treatment with meta-chlorophenylpiperazine (m-CPP) alters behavioral and cerebral metabolic responses to the serotonin agonists m-CPP and quipazine but not 8-hydroxy-2(di-N-propylamino)tetralin.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Brain; Deoxyglucose; Drug Interactions; Drug Tolerance; Male; Motor Activity; Piperazines; Quipazine; Rats; Rats, Inbred F344; Receptors, Serotonin; Tetrahydronaphthalenes | 1992 |
Parachloroamphetamine selectively alters regional cerebral metabolic responses to the serotonergic agonist metachlorophenylpiperazine in rats.
Topics: Animals; Arecoline; Biogenic Amines; Brain; Bromocriptine; Deoxyglucose; Hydroxyindoleacetic Acid; Kinetics; Male; Organ Specificity; p-Chloroamphetamine; Piperazines; Quipazine; Rats; Rats, Inbred F344; Serotonin | 1991 |
mCPP but not TFMPP is an antagonist at cardiac 5HT3 receptors.
Topics: Animals; Cerebral Cortex; Heart; Heart Rate; In Vitro Techniques; Male; Piperazines; Quipazine; Rats; Rats, Inbred Strains; Receptors, Serotonin | 1992 |
The inhibitory effect of trifluoromethylphenylpiperazine on [3H]acetylcholine release in guinea pig hippocampal synaptosomes is mediated by a 5-hydroxytryptamine1 receptor distinct from 1A, 1B, and 1C subtypes.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholine; Animals; Guinea Pigs; Hippocampus; Male; Piperazines; Potassium; Quinoxalines; Quipazine; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Synaptosomes; Tetrahydronaphthalenes | 1991 |
Effects of serotonin agonists on operant behavior in the squirrel monkey: quipazine, MK-212, trifluoromethylphenylpiperazine, and chlorophenylpiperazine.
Topics: Animals; Conditioning, Operant; Male; Piperazines; Pyrazines; Quipazine; Receptors, Serotonin; Saimiri; Serotonin Antagonists | 1990 |
Selective reduction by serotonergic agents of hypertonic saline consumption in rats: evidence for possible 5-HT1C receptor mediation.
Topics: Animals; Dose-Response Relationship, Drug; Drinking Behavior; Fenfluramine; Fluoxetine; Hypertonic Solutions; Indoles; Male; Piperazines; Pyrazines; Quinoxalines; Quipazine; Rats; Receptors, Serotonin; Serotonin | 1989 |
Induction of purposeless chewing behaviour in rats by 5-HT agonist drugs.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Male; Methiothepin; Methoxydimethyltryptamines; Mianserin; Parasympatholytics; Piperazines; Propranolol; Quipazine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Spiperone; Tetrahydronaphthalenes | 1989 |
Serotonin-antagonist effects of 1-(1-naphthyl)piperazine on operant behavior of squirrel monkeys.
Topics: Animals; Conditioning, Operant; DOM 2,5-Dimethoxy-4-Methylamphetamine; Electroshock; Female; Food; Male; Piperazines; Quipazine; Reinforcement Schedule; Saimiri; Serotonin Antagonists | 1989 |
Effects of serotonin receptor agonists and antagonists on schedule-controlled behavior of squirrel monkeys.
Topics: 5-Hydroxytryptophan; Animals; Cinanserin; Conditioning, Operant; Cyproheptadine; Electroshock; Female; Ketanserin; Male; Metergoline; Methysergide; Piperazines; Piperidines; Pyrazines; Quipazine; Receptors, Serotonin; Saimiri | 1985 |
Characterization of 5-hydroxytryptamine receptors in rat stomach fundus.
Topics: Animals; Binding, Competitive; Brain Chemistry; Gastric Fundus; In Vitro Techniques; Ketanserin; Male; Muscle Contraction; Piperazines; Piperidines; Propranolol; Pyrazines; Quipazine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Tritium | 1985 |
Further studies on the blockade of 5-HT depolarizations of rabbit vagal afferent and sympathetic ganglion cells by MDL 72222 and other antagonists.
Topics: Action Potentials; Animals; Female; Ganglia, Sympathetic; In Vitro Techniques; Male; Metoclopramide; Nodose Ganglion; Piperazines; Quipazine; Rabbits; Serotonin; Serotonin Antagonists; Tropanes; Vagus Nerve | 1987 |
Pharmacological characterization of 5-hydroxytryptamine-induced depolarization of the rat isolated vagus nerve.
Topics: Animals; Biguanides; Cocaine; In Vitro Techniques; Male; Piperazines; Quipazine; Rats; Serotonin; Serotonin Antagonists; Vagus Nerve | 1987 |
5-Hydroxytryptamine-like properties of m-chlorophenylpiperazine: comparison with quipazine.
Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Cyproheptadine; Dihydroxyphenylalanine; Piperazines; Quinolines; Quipazine; Rabbits; Rats; Receptors, Dopamine; Receptors, Serotonin; Serotonin; Time Factors; Tyrosine 3-Monooxygenase | 1980 |
Amitriptyline and femoxetine, but not clomipramine or citalopram, antagonize hyperthermia induced by directly acting 5-hydroxytryptamine-like drugs in heat adapted rats.
Topics: Adaptation, Physiological; Amitriptyline; Animals; Body Temperature; Citalopram; Clomipramine; Dose-Response Relationship, Drug; Hot Temperature; Male; Piperazines; Piperidines; Propylamines; Quipazine; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists | 1984 |
[Effect of serotoninergic substances on escape behavior in acute stress situations].
Topics: 5-Hydroxytryptophan; Animals; Antidepressive Agents; Brompheniramine; Cyproheptadine; Escape Reaction; Humans; Male; Piperazines; Piperidines; Quipazine; Rats; Rats, Inbred Strains; Serotonin; Stress, Psychological; Tranquilizing Agents; Trazodone; Zimeldine | 1983 |
[Neurochemical analysis of the mechanism of action of serotoninergic substances on avoidance behavior in situations of acute stress].
Topics: 5-Hydroxytryptophan; Acute Disease; Animals; Avoidance Learning; Cyproheptadine; Humans; Hydrazines; Male; Piperazines; Piperidines; Quinolines; Quipazine; Rats; Rats, Inbred Strains; Stress, Psychological; Tranquilizing Agents; Zimeldine | 1984 |
Further studies on the mechanism of serotonin-dependent anorexia in rats.
Topics: Animals; Anorexia; Brain; Feeding and Eating Disorders; Feeding Behavior; Female; Fenfluramine; Humans; Piperazines; Piperidines; Quipazine; Rats; Serotonin; Serotonin Antagonists; Synaptosomes; Time Factors | 1980 |
Antagonism of vascular serotonin receptors by m-chlorophenylpiperazine and m-trifluoromethylphenylpiperazine.
Topics: Animals; Depression, Chemical; Jugular Veins; Male; Muscle Contraction; Muscle, Smooth, Vascular; Piperazines; Quipazine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists | 1983 |
Inhibition of prolactin release by stimulation of presynaptic serotonin autoreceptors.
Topics: Animals; Brain Stem; Depression, Chemical; Male; Methoxydimethyltryptamines; Piperazines; Prolactin; Quipazine; Raphe Nuclei; Rats; Rats, Inbred Strains; Receptors, Serotonin | 1982 |
Reduction in the number of serotonin receptors in the brainstem of morphine dependent rats: relation to blockade of naloxone precipitated jumping by serotonin agonists.
Topics: Animals; Behavior, Animal; Brain Stem; Clonidine; Haloperidol; Humans; Male; Morphine Dependence; Naloxone; Piperazines; Propranolol; Quipazine; Rats; Receptors, Serotonin; Serotonin; Substance Withdrawal Syndrome | 1980 |
Evidence that it is possible to cause anorexia by increasing release and/or directly stimulating postsynaptic serotonin receptors in the brain.
Topics: Animals; Anorexia; Appetite Depressants; Brain; Feeding Behavior; Fenfluramine; Piperazines; Piperidines; Quipazine; Rats; Receptors, Serotonin; Serotonin; Synaptosomes | 1980 |
(1-(2,5-dimethoxy-4 iodophenyl)-2-aminopropane)-induced head-twitches in the rat are mediated by 5-hydroxytryptamine (5-HT) 2A receptors: modulation by novel 5-HT2A/2C antagonists, D1 antagonists and 5-HT1A agonists.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Behavior, Animal; Benzazepines; Dopamine Antagonists; Male; Piperazines; Quipazine; Rats; Rats, Wistar; Receptors, Adrenergic; Receptors, Dopamine D1; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 1995 |
Serotonin-mediated 5-HT2 receptor gene regulation in rat myometrial smooth muscle cells.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Biguanides; Cells, Cultured; Cycloheximide; Female; Gene Expression Regulation; Ketanserin; Medroxyprogesterone Acetate; Myometrium; Piperazines; Quipazine; Rats; Receptors, Serotonin; RNA, Messenger; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiperone; Sulpiride; Transcription, Genetic; Up-Regulation | 1993 |
5-HT2C receptor-mediated phosphoinositide turnover and the stimulus effects of m-chlorophenylpiperazine.
Topics: Animals; Choroid Plexus; Conditioning, Operant; DOM 2,5-Dimethoxy-4-Methylamphetamine; Drug Interactions; Ketanserin; Lysergic Acid Diethylamide; Ondansetron; Phosphatidylinositols; Piperazines; Pyrazines; Quipazine; Rats; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 1995 |
Characterisation of human 5-hydroxytryptamine2A and 5-hydroxytryptamine2C receptors expressed in the human neuroblastoma cell line SH-SY5Y: comparative stimulation by hallucinogenic drugs.
Topics: Adrenergic alpha-Agonists; Amphetamines; Antiparkinson Agents; Calcium; Choroid Plexus; Electrophysiology; Ergolines; Ergotamine; Frontal Lobe; Hallucinogens; Humans; Hydrolysis; Ketanserin; Lysergic Acid Diethylamide; Mescaline; Methoxydimethyltryptamines; Neuroblastoma; Phosphatidylinositols; Piperazines; Quipazine; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Recombinant Proteins; RNA, Messenger; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tritium; Tumor Cells, Cultured | 1996 |
Serotonergic mediation of fenfluramine discriminative stimuli in fawn-hooded rats.
Topics: Animals; Discrimination Learning; Dose-Response Relationship, Drug; Fenfluramine; Fluoxetine; Ibogaine; Male; Methoxydimethyltryptamines; N-Methyl-3,4-methylenedioxyamphetamine; Piperazines; Quipazine; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Agents; Serotonin Receptor Agonists | 1997 |
Brain-to-blood partition and in vivo inhibition of 5-hydroxytryptamine reuptake and quipazine-mediated behaviour of nefazodone and its main active metabolites in rodents.
Topics: Animals; Blood-Brain Barrier; Brain; Cerebral Cortex; Head Movements; Male; Mice; p-Chloroamphetamine; Piperazines; Prodrugs; Quipazine; Rats; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents; Serotonin Receptor Agonists; Triazoles | 1998 |
Comparison of the potency of MDL 100,907 and SB 242084 in blocking the serotonin (5-HT)(2) receptor agonist-induced increases in rat serum corticosterone concentrations: evidence for 5-HT(2A) receptor mediation of the HPA axis.
Topics: Aminopyridines; Amphetamines; Animals; Corticosterone; Dose-Response Relationship, Drug; Ethylamines; Fluorobenzenes; Hypothalamo-Hypophyseal System; Indoles; Male; Piperazines; Piperidines; Quipazine; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 2002 |
Metachlorophenylpiperazine (m-CPP) induced intracavernous pressure responses in anaesthetized rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Anesthesia; Animals; Male; Penile Erection; Penis; Piperazines; Pressure; Quipazine; Rats; Rats, Sprague-Dawley; Serotonin Receptor Agonists; Sexual Behavior, Animal | 2002 |
Differential effects of 5-HT1 and 5-HT2 receptor agonists on hindlimb movements in paraplegic mice.
Topics: Analysis of Variance; Animals; Antiparkinson Agents; Disease Models, Animal; Drug Interactions; Exercise Test; Hindlimb; Levodopa; Locomotion; Male; Mice; Movement; Paraplegia; Piperazines; Pyridines; Quipazine; Receptors, Serotonin, 5-HT1; Receptors, Serotonin, 5-HT2; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT2 Receptor Agonists; Serotonin Receptor Agonists; Spinal Cord Injuries | 2004 |