1-(3-chlorophenyl)piperazine has been researched along with pyrazines in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (33.33) | 18.7374 |
| 1990's | 8 (38.10) | 18.2507 |
| 2000's | 4 (19.05) | 29.6817 |
| 2010's | 2 (9.52) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barr, LC; Charney, DS; Goodman, WK; McDougle, CJ; Price, LH | 1 |
| Berendsen, HH; Broekkamp, CL | 1 |
| McKearney, JW | 2 |
| Cooper, SJ; Neill, JC | 1 |
| Brazell, C; Dourish, CT; King, BH; Middlemiss, DN | 1 |
| Frazer, A; Lucki, I; Ward, HR | 1 |
| Barrett, JE; Brady, LS | 1 |
| Clineschmidt, BV; Pettibone, DJ; Reiss, DR; Robinson, JL | 1 |
| Harris, LT; McCall, RB; Patel, BN | 1 |
| Rabin, RA; Winter, JC | 1 |
| Fiorella, D; Helsley, S; Rabin, RA; Winter, JC | 1 |
| Baumgarten, HG; Grozdanovic, Z | 1 |
| Dekeyne, A; Girardon, S; Millan, MJ | 1 |
| George, FR; Kreifeldt, MJ; O'Dell, LE; Ritz, MC | 1 |
| Di Giovanni, G; Di Mascio, M; Di Matteo, V; Esposito, E | 1 |
| Brown, EK; Hass, RW; Kohut, SJ; Lefever, T; Prabandham, A; Walker, EA | 1 |
| Goto, F; Ito, N; Obata, H; Saito, S; Sasaki, M | 1 |
| Fletcher, PJ; Higgins, GA; Isaac, M; Sinyard, J; Slassi, A; Tampakeras, M | 1 |
| Foley, JJ; Walker, EA | 1 |
| de Andrade, TGCS; Hernandes, PM; Sant'Ana, AB; Vicente, MA; Vilela-Costa, HH; Zangrossi, H | 1 |
2 review(s) available for 1-(3-chlorophenyl)piperazine and pyrazines
| Article | Year |
|---|---|
The serotonin hypothesis of obsessive compulsive disorder: implications of pharmacologic challenge studies.
Topics: Biomarkers; Clomipramine; Humans; Neurotransmitter Uptake Inhibitors; Obsessive-Compulsive Disorder; Piperazines; Pyrazines; Pyrimidines; Serotonin | 1992 |
Role of serotonin in obsessive-compulsive disorder.
Topics: Biogenic Monoamines; Fenfluramine; Humans; Neuropeptides; Obsessive-Compulsive Disorder; Piperazines; Pyrazines; Pyrimidines; Serotonin; Serotonin Syndrome; Synaptic Transmission; Tryptophan | 1998 |
19 other study(ies) available for 1-(3-chlorophenyl)piperazine and pyrazines
| Article | Year |
|---|---|
Behavioural evidence for functional interactions between 5-HT-receptor subtypes in rats and mice.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Behavior, Animal; Body Temperature; Male; Mice; Mice, Inbred ICR; Motor Activity; Piperazines; Pyrazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes | 1990 |
Effects of serotonin agonists on operant behavior in the squirrel monkey: quipazine, MK-212, trifluoromethylphenylpiperazine, and chlorophenylpiperazine.
Topics: Animals; Conditioning, Operant; Male; Piperazines; Pyrazines; Quipazine; Receptors, Serotonin; Saimiri; Serotonin Antagonists | 1990 |
Selective reduction by serotonergic agents of hypertonic saline consumption in rats: evidence for possible 5-HT1C receptor mediation.
Topics: Animals; Dose-Response Relationship, Drug; Drinking Behavior; Fenfluramine; Fluoxetine; Hypertonic Solutions; Indoles; Male; Piperazines; Pyrazines; Quinoxalines; Quipazine; Rats; Receptors, Serotonin; Serotonin | 1989 |
MK-212 increases rat plasma ACTH concentration by activation of the 5-HT1C receptor subtype.
Topics: Adrenocorticotropic Hormone; Animals; Antiparkinson Agents; Ergolines; Ketanserin; Male; Metergoline; Pindolol; Piperazines; Pyrazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Spiperone | 1989 |
Effect of 1-(m-chlorophenyl)piperazine and 1-(m-trifluoromethylphenyl)piperazine on locomotor activity.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Male; Monoamine Oxidase Inhibitors; Motor Activity; Piperazines; Pyrazines; Rats; Rats, Inbred Strains; Receptors, Serotonin | 1989 |
Apparent antinociceptive properties of piperazine-type serotonin agonists: trifluoromethylphenylpiperazine, chlorophenylpiperazine, and MK-212.
Topics: Animals; Dose-Response Relationship, Drug; Male; Methysergide; Nociceptors; Piperazines; Pyrazines; Receptors, Serotonin; Saimiri | 1989 |
Effects of serotonin receptor agonists and antagonists on schedule-controlled behavior of squirrel monkeys.
Topics: 5-Hydroxytryptophan; Animals; Cinanserin; Conditioning, Operant; Cyproheptadine; Electroshock; Female; Ketanserin; Male; Metergoline; Methysergide; Piperazines; Piperidines; Pyrazines; Quipazine; Receptors, Serotonin; Saimiri | 1985 |
Characterization of 5-hydroxytryptamine receptors in rat stomach fundus.
Topics: Animals; Binding, Competitive; Brain Chemistry; Gastric Fundus; In Vitro Techniques; Ketanserin; Male; Muscle Contraction; Piperazines; Piperidines; Propranolol; Pyrazines; Quipazine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Tritium | 1985 |
Effects of serotonin1 and serotonin2 receptor agonists and antagonists on blood pressure, heart rate and sympathetic nerve activity.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Blood Pressure; Cats; Heart Rate; Piperazines; Pyrazines; Receptors, Serotonin; Serotonin Antagonists; Sympathetic Nervous System; Tetrahydronaphthalenes | 1987 |
Discriminative stimulus properties of m-chlorophenylpiperazine.
Topics: Animals; Discrimination Learning; Generalization, Stimulus; Indoles; Male; Piperazines; Pyrazines; Rats; Rats, Inbred F344; Serotonin Antagonists; Serotonin Receptor Agonists | 1993 |
5-HT2C receptor-mediated phosphoinositide turnover and the stimulus effects of m-chlorophenylpiperazine.
Topics: Animals; Choroid Plexus; Conditioning, Operant; DOM 2,5-Dimethoxy-4-Methylamphetamine; Drug Interactions; Ketanserin; Lysergic Acid Diethylamide; Ondansetron; Phosphatidylinositols; Piperazines; Pyrazines; Quipazine; Rats; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 1995 |
Discriminative stimulus properties of the novel serotonin (5-HT)2C receptor agonist, RO 60-0175: a pharmacological analysis.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Conditioning, Operant; Ethylamines; Fluorobenzenes; Indoles; Male; Mianserin; Piperazines; Piperidines; Pyrazines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Reinforcement, Psychology; Serotonin Antagonists; Serotonin Receptor Agonists; Thiophenes | 1999 |
Serotonin(2C) receptors appear to mediate genetic sensitivity to cocaine-induced convulsions.
Topics: Animals; Cocaine; Male; Mice; Mice, Inbred C57BL; Piperazines; Pyrazines; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Seizures; Species Specificity | 1999 |
Preferential modulation of mesolimbic vs. nigrostriatal dopaminergic function by serotonin(2C/2B) receptor agonists: a combined in vivo electrophysiological and microdialysis study.
Topics: Aminopyridines; Animals; Dopamine; Indoles; Male; Neostriatum; Neurons; Nucleus Accumbens; Piperazines; Pyrazines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Substantia Nigra; Ventral Tegmental Area | 2000 |
Selective and nonselective serotonin antagonists block the aversive stimulus properties of MK212 and m-chlorophenylpiperazine (mCPP) in mice.
Topics: Animals; Avoidance Learning; Conditioning, Operant; Cues; Dose-Response Relationship, Drug; Lithium Chloride; Lysergic Acid Diethylamide; Male; Mianserin; Mice; Piperazines; Pyrazines; Receptor, Serotonin, 5-HT2C; Reinforcement, Psychology; Serotonin Antagonists; Taste | 2005 |
Possible involvement of spinal noradrenergic mechanisms in the antiallodynic effect of intrathecally administered 5-HT2C receptor agonists in the rats with peripheral nerve injury.
Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Atropine; Injections, Spinal; Ligation; Male; Muscarinic Antagonists; Norepinephrine; Pain; Peripheral Nervous System Diseases; Physical Stimulation; Piperazines; Pyrazines; Rats; Rats, Wistar; Serotonin 5-HT2 Receptor Agonists; Spinal Cord; Spinal Nerves; Touch; Yohimbine | 2007 |
Characterizing the effects of 5-HT(2C) receptor ligands on motor activity and feeding behaviour in 5-HT(2C) receptor knockout mice.
Topics: Aminopyridines; Animals; Benzazepines; Dexfenfluramine; Eating; Ethylamines; Feeding Behavior; Indoles; Ligands; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Naphthyridines; Piperazines; Pyrazines; Quinoxalines; Receptor, Serotonin, 5-HT2C; Serotonin Antagonists; Serotonin Receptor Agonists | 2009 |
Acquisition session length modulates consolidation effects produced by 5-HT2C ligands in a mouse autoshaping-operant procedure.
Topics: Animals; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Inverse Agonism; Drug Partial Agonism; Indoles; Ligands; Lysergic Acid Diethylamide; Male; Memory; Methysergide; Mianserin; Mice; Piperazines; Pyrazines; Pyridines; Reinforcement Schedule; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists; Time Factors | 2010 |
Role of 5-HT2C receptors of the dorsal hippocampus in the modulation of anxiety- and panic-related defensive responses in rats.
Topics: Aminopyridines; Animals; Anti-Anxiety Agents; Anxiety; Avoidance Learning; Ethylamines; Hippocampus; Imipramine; Indoles; Male; Maze Learning; Microinjections; Panic; Piperazines; Punishment; Pyrazines; Rats; Receptor, Serotonin, 5-HT2C; Serotonin 5-HT2 Receptor Agonists | 2019 |