Compounds > 1-(3-chlorophenyl)piperazine

1-(3-chlorophenyl)piperazine and n-methyl-3,4-methylenedioxyamphetamine

1-(3-chlorophenyl)piperazine has been researched along with n-methyl-3,4-methylenedioxyamphetamine in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (9.52)18.2507
2000's9 (42.86)29.6817
2010's9 (42.86)24.3611
2020's1 (4.76)2.80

Authors

AuthorsStudies
Schechter, MD1
Eligulashvili, V; McCann, UD; Mertl, M; Murphy, DL; Ricaurte, GA1
Colado, MI; Elliott, JM; Green, AR; Mechan, AO; O'Shea, E1
Johanson, CE; Tancer, ME1
Delatte, MS; McCann, UD; Moerschbaecher, JM; Ricaurte, GA; Stevenson, MW; Winsauer, PJ; Yuan, J1
Hatzidimitriou, G; McCann, UD; Ricaurte, GA; Tsai, EH1
Ceglia, I; Gobbi, M; Mennini, T; Moia, M; Pirona, L; Reyes-Parada, M; Scorza, C1
Bull, EJ; Fone, KC; Hutson, PH1
Gatchalian, K; Johanson, CE; Kilbey, M; Tancer, M1
Bossong, MG; Niesink, RJ; Van Dijk, JP1
Coop, A; Fantegrossi, WE; Katz, EB; Yarosh, HL1
Bossong, MG; Brunt, TM; Goldschmidt, HM; Hoek, J; Niesink, RJ; Rigter, SM; Van Dijk, JP1
Adori, C; Andó, RD; Bagdy, G; Ferrington, L; Kelly, PA; Kirilly, E; Kovács, GG; Molnár, E1
Brennan, KA; Colussi-Mas, J; Jones, K; Schenk, S1
Costantino, AG; Logan, BK; Rieders, EF; Sanders, D1
Hondebrink, L; Meulenbelt, J; van den Berg, M; van Kleef, RG; Westerink, RH1
Dickson, AJ; Holler, JM; Lyons, TP; Vorce, SP1
Hondebrink, L; Meijer, M; Meulenbelt, J; Rietjens, SJ; Westerink, RH1
Hermans, E; Hondebrink, L; Meulenbelt, J; Tan, S; van Kleef, RG; Westerink, RH1
Angnes, L; Blanes, L; do Lago, CL; Doble, P; Nogueira, T; Porto, SK; Sabino, BD1
Arantes, LC; Dos Santos, WTP; Lima, CD; Melo, LMA; Munoz, RAA; Richter, EM; Rocha, RG; Silva, WP1

Trials

2 trial(s) available for 1-(3-chlorophenyl)piperazine and n-methyl-3,4-methylenedioxyamphetamine

ArticleYear
Altered neuroendocrine and behavioral responses to m-chlorophenylpiperazine in 3,4-methylenedioxymethamphetamine (MDMA) users.
    Psychopharmacology, 1999, Volume: 147, Issue:1

    Topics: Adult; Affect; Anxiety; Behavior; Female; Hallucinogens; Humans; Hydrocortisone; Male; N-Methyl-3,4-methylenedioxyamphetamine; Neurosecretory Systems; Piperazines; Prolactin; Serotonin; Serotonin Receptor Agonists; Single-Blind Method

1999
Discriminative stimulus effects of 3,4-methylenedioxymethamphetamine (MDMA) in humans trained to discriminate among d-amphetamine, meta-chlorophenylpiperazine and placebo.
    Drug and alcohol dependence, 2006, Jan-04, Volume: 81, Issue:1

    Topics: Adult; Alcoholism; Amphetamine-Related Disorders; Arousal; Dextroamphetamine; Discrimination Learning; Dopamine Agonists; Dose-Response Relationship, Drug; Double-Blind Method; Female; Hallucinogens; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine; Piperazines; Serotonin Agents

2006

Other Studies

19 other study(ies) available for 1-(3-chlorophenyl)piperazine and n-methyl-3,4-methylenedioxyamphetamine

ArticleYear
Serotonergic mediation of fenfluramine discriminative stimuli in fawn-hooded rats.
    Life sciences, 1997, Volume: 60, Issue:6

    Topics: Animals; Discrimination Learning; Dose-Response Relationship, Drug; Fenfluramine; Fluoxetine; Ibogaine; Male; Methoxydimethyltryptamines; N-Methyl-3,4-methylenedioxyamphetamine; Piperazines; Quipazine; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Agents; Serotonin Receptor Agonists

1997
A neurotoxic dose of 3,4-methylenedioxymethamphetamine (MDMA; ecstasy) to rats results in a long-term defect in thermoregulation.
    Psychopharmacology, 2001, Volume: 155, Issue:4

    Topics: Amphetamines; Animals; Body Temperature; Body Temperature Regulation; Brain Chemistry; Hallucinogens; Hydroxyindoleacetic Acid; Male; N-Methyl-3,4-methylenedioxyamphetamine; Neurotoxicity Syndromes; Piperazines; Rats; Serotonin; Serotonin Receptor Agonists

2001
The subjective effects of MDMA and mCPP in moderate MDMA users.
    Drug and alcohol dependence, 2001, Dec-01, Volume: 65, Issue:1

    Topics: Adolescent; Adult; Affect; Analysis of Variance; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Female; Hallucinogens; Heart Rate; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine; Piperazines; Serotonin Receptor Agonists; Substance-Related Disorders

2001
Effects of fenfluramine, m-CPP and triazolam on repeated-acquisition in squirrel monkeys before and after neurotoxic MDMA administration.
    Psychopharmacology, 2002, Volume: 159, Issue:4

    Topics: Animals; Behavior, Animal; Brain; Dose-Response Relationship, Drug; Fenfluramine; GABA Modulators; Hydroxyindoleacetic Acid; Learning; N-Methyl-3,4-methylenedioxyamphetamine; Piperazines; Reaction Time; Saimiri; Serotonin; Serotonin Agents; Serotonin Receptor Agonists; Triazolam

2002
Altered prolactin response to M-chlorophenylpiperazine in monkeys previously treated with 3,4-methylenedioxymethamphetamine (MDMA) or fenfluramine.
    Synapse (New York, N.Y.), 2002, Volume: 44, Issue:1

    Topics: Animals; Drug Administration Schedule; Drug Interactions; Fenfluramine; Hydrocortisone; Hypothalamus; Male; N-Methyl-3,4-methylenedioxyamphetamine; Neurotoxins; Piperazines; Presynaptic Terminals; Prolactin; Raphe Nuclei; Reaction Time; Saimiri; Serotonin Agents

2002
p-Methylthioamphetamine and 1-(m-chlorophenyl)piperazine, two non-neurotoxic 5-HT releasers in vivo, differ from neurotoxic amphetamine derivatives in their mode of action at 5-HT nerve endings in vitro.
    Journal of neurochemistry, 2002, Volume: 82, Issue:6

    Topics: Amphetamines; Animals; Binding, Competitive; Brain Chemistry; Carrier Proteins; Citalopram; Dose-Response Relationship, Drug; Hippocampus; Membrane Glycoproteins; Membrane Transport Proteins; Microdialysis; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Endings; Nerve Tissue Proteins; p-Chloroamphetamine; Piperazines; Rats; Serotonin; Serotonin Agents; Serotonin Plasma Membrane Transport Proteins; Synaptosomes; Tritium

2002
Reduced social interaction following 3,4-methylenedioxymethamphetamine is not associated with enhanced 5-HT 2C receptor responsivity.
    Neuropharmacology, 2003, Volume: 44, Issue:4

    Topics: Animals; Brain; Corticosterone; Exploratory Behavior; Hydroxyindoleacetic Acid; Hypothermia; In Vitro Techniques; Male; Maze Learning; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Paroxetine; Piperazines; Radioligand Assay; Rats; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Serotonin; Serotonin Agents; Serotonin Receptor Agonists; Social Behavior; Substance Withdrawal Syndrome

2003
Methylone and mCPP, two new drugs of abuse?
    Addiction biology, 2005, Volume: 10, Issue:4

    Topics: Adrenergic Uptake Inhibitors; Biogenic Monoamines; Cross-Sectional Studies; Designer Drugs; Humans; Illicit Drugs; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Netherlands; Piperazines; Receptors, Serotonin; Serotonin Receptor Agonists; Substance-Related Disorders

2005
MDMA-like behavioral effects of N-substituted piperazines in the mouse.
    Pharmacology, biochemistry, and behavior, 2007, Volume: 88, Issue:1

    Topics: Animals; Behavior, Animal; Biogenic Monoamines; Cues; Data Interpretation, Statistical; Discrimination, Psychological; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Hallucinogens; Male; Mice; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Piperazines; Stereoisomerism

2007
mCPP: an undesired addition to the ecstasy market.
    Journal of psychopharmacology (Oxford, England), 2010, Volume: 24, Issue:9

    Topics: Drug Combinations; Gas Chromatography-Mass Spectrometry; Hallucinogens; Humans; Illicit Drugs; N-Methyl-3,4-methylenedioxyamphetamine; Netherlands; Piperazines

2010
Acute SSRI-induced anxiogenic and brain metabolic effects are attenuated 6 months after initial MDMA-induced depletion.
    Behavioural brain research, 2010, Mar-05, Volume: 207, Issue:2

    Topics: Animals; Anxiety; Axons; Brain; Citalopram; Fluoxetine; Male; N-Methyl-3,4-methylenedioxyamphetamine; Neurons; Neuropsychological Tests; Piperazines; Rats; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents; Serotonin Receptor Agonists; Social Behavior; Time Factors

2010
Tolerance to 3,4-methylenedioxymethamphetamine is associated with impaired serotonin release.
    Addiction biology, 2010, Volume: 15, Issue:3

    Topics: Amphetamines; Animals; Brain; Dose-Response Relationship, Drug; Drug Tolerance; Exploratory Behavior; Fenfluramine; Male; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Piperazines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Serotonin; Serotonin Agents; Serotonin Receptor Agonists

2010
Trazodone, meta-chlorophenylpiperazine (an hallucinogenic drug and trazodone metabolite), and the hallucinogen trifluoromethylphenylpiperazine cross-react with the EMIT®II ecstasy immunoassay in urine.
    Journal of analytical toxicology, 2010, Volume: 34, Issue:9

    Topics: Antidepressive Agents; Cross Reactions; False Positive Reactions; Hallucinogens; Humans; Illicit Drugs; Immunoassay; N-Methyl-3,4-methylenedioxyamphetamine; Piperazines; Reagent Kits, Diagnostic; Substance Abuse Detection; Substance-Related Disorders; Trazodone

2010
Modulation of human GABAA receptor function: a novel mode of action of drugs of abuse.
    Neurotoxicology, 2011, Volume: 32, Issue:6

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Binding, Competitive; Dose-Response Relationship, Drug; GABA Modulators; gamma-Aminobutyric Acid; Humans; Illicit Drugs; Membrane Potentials; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Oocytes; Patch-Clamp Techniques; Piperazines; Receptors, GABA-A; Time Factors; Xenopus laevis

2011
Detection of 1-benzylpiperazine, 1-(3-trifluoromethylphenyl)-piperazine, and 1-(3-chlorophenyl)-piperazine in 3,4-methylenedioxymethamphetamine-positive urine samples.
    Journal of analytical toxicology, 2010, Volume: 34, Issue:8

    Topics: 3,4-Methylenedioxyamphetamine; Central Nervous System Stimulants; Designer Drugs; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Piperazines; Reproducibility of Results; Substance Abuse Detection; Urinalysis

2010
Methamphetamine, amphetamine, MDMA ('ecstasy'), MDA and mCPP modulate electrical and cholinergic input in PC12 cells.
    Neurotoxicology, 2012, Volume: 33, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Adrenergic Agents; Amphetamine; Animals; Calcium; Cholinergic Agents; Dose-Response Relationship, Drug; Membrane Potentials; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; PC12 Cells; Piperazines; Potassium Chloride; Rats; Serotonin Receptor Agonists

2012
Additive inhibition of human α1β2γ2 GABAA receptors by mixtures of commonly used drugs of abuse.
    Neurotoxicology, 2013, Volume: 35

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Cocaine; Dose-Response Relationship, Drug; Drug Interactions; GABA Antagonists; Humans; Membrane Potentials; N-Methyl-3,4-methylenedioxyamphetamine; Oocytes; Patch-Clamp Techniques; Piperazines; Receptors, GABA-A; Xenopus laevis

2013
Analysis of ecstasy tablets using capillary electrophoresis with capacitively coupled contactless conductivity detection.
    Journal of forensic sciences, 2014, Volume: 59, Issue:6

    Topics: Acetic Acid; Drug Trafficking; Electric Conductivity; Electrophoresis, Capillary; Gas Chromatography-Mass Spectrometry; Hallucinogens; Humans; Lithium Compounds; N-Methyl-3,4-methylenedioxyamphetamine; Piperazines; Serotonin Receptor Agonists; Sulfonic Acids; Tablets

2014
Development of a simple and rapid screening method for the detection of 1-(3-chlorophenyl)piperazine in forensic samples.
    Talanta, 2021, Oct-01, Volume: 233

    Topics: Amphetamines; Electrodes; N-Methyl-3,4-methylenedioxyamphetamine; Piperazines

2021