1-(3-chlorophenyl)piperazine and 5-methoxytryptamine

1-(3-chlorophenyl)piperazine has been researched along with 5-methoxytryptamine in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19902 (18.18)18.7374
1990's6 (54.55)18.2507
2000's3 (27.27)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hamblin, MW; Metcalf, MA1
Glennon, RA2
Hamblin, MW; Monsma, FJ; Shen, Y; Sibley, DR; Ward, RP1
Hamblin, MW; Jose, PA; Metcalf, MA; Monsma, FJ; Shen, Y; Sibley, DR1
Audia, JE; Baez, M; Cohen, ML; Kursar, JD; Lucaites, VL; Nelson, DL; Nissen, JS; Schenck, KW; Wainscott, DB1
Carrupt, PA; Gaillard, P; Schambel, P; Testa, B1
Dupre, A; Egan, C; Grinde, E; Hake, M; Herrick-Davis, K; Roth, BL; Teitler, M1
Bai, F; Johnstone, EM; Little, SP; Nelson, DL; Su, C; Varga, G; Yin, T1
Wielosz, M1
Chung, M; Fraga, K; Frieman, VB; Illuzzi, FA; O'Gara, BA; Portnoy, AD1

Reviews

2 review(s) available for 1-(3-chlorophenyl)piperazine and 5-methoxytryptamine

ArticleYear
Central serotonin receptors as targets for drug research.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:1

    Topics: Animals; Humans; Receptors, Serotonin; Research Design; Serotonin

1987
Higher-end serotonin receptors: 5-HT(5), 5-HT(6), and 5-HT(7).
    Journal of medicinal chemistry, 2003, Jul-03, Volume: 46, Issue:14

    Topics: Animals; Humans; Ligands; Receptors, Serotonin; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists

2003

Other Studies

9 other study(ies) available for 1-(3-chlorophenyl)piperazine and 5-methoxytryptamine

ArticleYear
Primary structure and functional characterization of a human 5-HT1D-type serotonin receptor.
    Molecular pharmacology, 1991, Volume: 40, Issue:2

    Topics: Amino Acid Sequence; Base Sequence; Cloning, Molecular; Cyclic AMP; GTP-Binding Proteins; Humans; Molecular Sequence Data; Pertussis Toxin; Receptors, Serotonin; Virulence Factors, Bordetella

1991
Cloning and expression of a novel serotonin receptor with high affinity for tricyclic psychotropic drugs.
    Molecular pharmacology, 1993, Volume: 43, Issue:3

    Topics: Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Blotting, Northern; Brain Chemistry; Cell Line; Cloning, Molecular; DNA; GTP-Binding Proteins; Lysergic Acid Diethylamide; Molecular Sequence Data; Polymerase Chain Reaction; Psychotropic Drugs; Rats; Receptors, Serotonin; RNA; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Transfection

1993
Molecular cloning and expression of a 5-hydroxytryptamine7 serotonin receptor subtype.
    The Journal of biological chemistry, 1993, Aug-25, Volume: 268, Issue:24

    Topics: Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Cell Line; Cell Membrane; Cloning, Molecular; Cyclic AMP; Gene Expression; Kidney Tubules, Proximal; Lysergic Acid Diethylamide; Molecular Sequence Data; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Radioligand Assay; Rats; Receptors, Serotonin; Recombinant Proteins; Serotonin; Transfection

1993
Pharmacological characteristics of the newly cloned rat 5-hydroxytryptamine2F receptor.
    Molecular pharmacology, 1993, Volume: 43, Issue:3

    Topics: Animals; Binding Sites; Cell Line; Cloning, Molecular; Gastric Fundus; Inositol 1,4,5-Trisphosphate; Male; Muscle Contraction; Muscle, Smooth; Radioligand Assay; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Temperature

1993
Binding of arylpiperazines, (aryloxy)propanolamines, and tetrahydropyridylindoles to the 5-HT1A receptor: contribution of the molecular lipophilicity potential to three-dimensional quantitative structure-affinity relationship models.
    Journal of medicinal chemistry, 1996, Jan-05, Volume: 39, Issue:1

    Topics: Indoles; Ligands; Models, Molecular; Molecular Conformation; Molecular Structure; Piperazines; Propanolamines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Structure-Activity Relationship; Tetrahydronaphthalenes

1996
Agonist high and low affinity state ratios predict drug intrinsic activity and a revised ternary complex mechanism at serotonin 5-HT(2A) and 5-HT(2C) receptors.
    Synapse (New York, N.Y.), 2000, Volume: 35, Issue:2

    Topics: Animals; Cell Line; Computer Simulation; GTP-Binding Proteins; Inositol Phosphates; Kinetics; Phosphatidylinositols; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Recombinant Proteins; Serotonin Receptor Agonists; Signal Transduction; Transfection; Tritium

2000
Molecular cloning and pharmacological characterization of the guinea pig 5-HT1E receptor.
    European journal of pharmacology, 2004, Jan-26, Volume: 484, Issue:2-3

    Topics: Amino Acid Sequence; Animals; Base Sequence; Brain; Chickens; Cloning, Molecular; Cricetinae; Dose-Response Relationship, Drug; Gerbillinae; Guinea Pigs; Haplorhini; Humans; Molecular Sequence Data; Protein Binding; Rabbits; Receptors, Serotonin; Serotonin Agents; Swine

2004
Increased sensitivity to serotonergic agonists after repeated electroconvulsive shock in rats.
    Pharmacology, biochemistry, and behavior, 1985, Volume: 22, Issue:5

    Topics: 5-Hydroxytryptophan; 5-Methoxytryptamine; Animals; Brain; Chlorides; Cyproheptadine; Electroshock; Fenfluramine; Lithium; Lithium Chloride; Male; Metergoline; Motor Activity; Piperazines; Rats; Serotonin; Synaptic Transmission

1985
Serotonin induces four pharmacologically separable contractile responses in the pharynx of the leech Hirudo medicinalis.
    General pharmacology, 1999, Volume: 32, Issue:6

    Topics: 5-Methoxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Dose-Response Relationship, Drug; Electric Stimulation; In Vitro Techniques; Leeches; Muscle Contraction; Pharynx; Piperazines; Serotonin; Serotonin Receptor Agonists

1999