Compounds > 1-(3-chlorophenyl)piperazine

1-(3-chlorophenyl)piperazine and 1-(1-naphthyl)piperazine

1-(3-chlorophenyl)piperazine has been researched along with 1-(1-naphthyl)piperazine in 14 studies

Research

Studies (14)

Timeframe	Studies, this research(%)	All Research%
pre-1990	4 (28.57)	18.7374
1990's	7 (50.00)	18.2507
2000's	2 (14.29)	29.6817
2010's	1 (7.14)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
el-Ashmawy, MB; Fischer, JB; Glennon, RA; Herndon, JL; Howie, KJ; Ismaiel, AM; Server, AC; Yousif, MY	1
Glennon, RA; Lyon, RA; Naiman, NA; Titeler, M	1
Glennon, RA	2
Hamblin, MW; Monsma, FJ; Shen, Y; Sibley, DR; Ward, RP	1
Hamblin, MW; Jose, PA; Metcalf, MA; Monsma, FJ; Shen, Y; Sibley, DR	1
Audia, JE; Baez, M; Cohen, ML; Kursar, JD; Lucaites, VL; Nelson, DL; Nissen, JS; Schenck, KW; Wainscott, DB	1
Carrupt, PA; Gaillard, P; Schambel, P; Testa, B	1
Abdel-Rahman, AA; Dukat, M; Glennon, RA; Gyermek, L; Ingher, S; Ismaiel, AM; Teitler, M	1
Baez, M; Kursar, JD; Lucaites, VL; Nelson, DL; Sasso, DA; Wainscott, DB	1
Bai, F; Johnstone, EM; Little, SP; Nelson, DL; Su, C; Varga, G; Yin, T	1
Berardi, F; Caroli, A; Colabufo, NA; Contino, M; De Giorgio, P; Di Pilato, P; Hedlund, PB; Lacivita, E; Leopoldo, M; Niso, M; Patarnello, D; Perrone, R; Stroth, N; Svenningsson, P	1
McKearney, JW	1
Schechter, LE; Simansky, KJ	1

Reviews

2 review(s) available for 1-(3-chlorophenyl)piperazine and 1-(1-naphthyl)piperazine

Article	Year
Central serotonin receptors as targets for drug research. Journal of medicinal chemistry, 1987, Volume: 30, Issue:1 Topics: Animals; Humans; Receptors, Serotonin; Research Design; Serotonin	1987
Higher-end serotonin receptors: 5-HT(5), 5-HT(6), and 5-HT(7). Journal of medicinal chemistry, 2003, Jul-03, Volume: 46, Issue:14 Topics: Animals; Humans; Ligands; Receptors, Serotonin; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists	2003

Other Studies

12 other study(ies) available for 1-(3-chlorophenyl)piperazine and 1-(1-naphthyl)piperazine

Article	Year
Novel 1-phenylpiperazine and 4-phenylpiperidine derivatives as high-affinity sigma ligands. Journal of medicinal chemistry, 1991, Volume: 34, Issue:12 Topics: Animals; Guinea Pigs; In Vitro Techniques; Ligands; Piperazines; Piperidines; Radioligand Assay; Receptors, Dopamine; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Phencyclidine; Receptors, sigma; Structure-Activity Relationship	1991
Arylpiperazine derivatives as high-affinity 5-HT1A serotonin ligands. Journal of medicinal chemistry, 1988, Volume: 31, Issue:10 Topics: Animals; Chemical Phenomena; Chemistry; Male; Piperazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Structure-Activity Relationship	1988
Cloning and expression of a novel serotonin receptor with high affinity for tricyclic psychotropic drugs. Molecular pharmacology, 1993, Volume: 43, Issue:3 Topics: Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Blotting, Northern; Brain Chemistry; Cell Line; Cloning, Molecular; DNA; GTP-Binding Proteins; Lysergic Acid Diethylamide; Molecular Sequence Data; Polymerase Chain Reaction; Psychotropic Drugs; Rats; Receptors, Serotonin; RNA; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Transfection	1993
Molecular cloning and expression of a 5-hydroxytryptamine7 serotonin receptor subtype. The Journal of biological chemistry, 1993, Aug-25, Volume: 268, Issue:24 Topics: Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Cell Line; Cell Membrane; Cloning, Molecular; Cyclic AMP; Gene Expression; Kidney Tubules, Proximal; Lysergic Acid Diethylamide; Molecular Sequence Data; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Radioligand Assay; Rats; Receptors, Serotonin; Recombinant Proteins; Serotonin; Transfection	1993
Pharmacological characteristics of the newly cloned rat 5-hydroxytryptamine2F receptor. Molecular pharmacology, 1993, Volume: 43, Issue:3 Topics: Animals; Binding Sites; Cell Line; Cloning, Molecular; Gastric Fundus; Inositol 1,4,5-Trisphosphate; Male; Muscle Contraction; Muscle, Smooth; Radioligand Assay; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Temperature	1993
Binding of arylpiperazines, (aryloxy)propanolamines, and tetrahydropyridylindoles to the 5-HT1A receptor: contribution of the molecular lipophilicity potential to three-dimensional quantitative structure-affinity relationship models. Journal of medicinal chemistry, 1996, Jan-05, Volume: 39, Issue:1 Topics: Indoles; Ligands; Models, Molecular; Molecular Conformation; Molecular Structure; Piperazines; Propanolamines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Structure-Activity Relationship; Tetrahydronaphthalenes	1996
Structure-activity relationships for the binding of arylpiperazines and arylbiguanides at 5-HT3 serotonin receptors. Journal of medicinal chemistry, 1996, Sep-27, Volume: 39, Issue:20 Topics: Animals; Biguanides; Heart Rate; Male; Molecular Structure; Muscle Contraction; Piperazines; Rabbits; Rats; Receptors, Serotonin; Reflex; Serotonin Antagonists; Serotonin Receptor Agonists; Structure-Activity Relationship; Urinary Bladder	1996
[3H]Rauwolscine: an antagonist radioligand for the cloned human 5-hydroxytryptamine2b (5-HT2B) receptor. Naunyn-Schmiedeberg's archives of pharmacology, 1998, Volume: 357, Issue:1 Topics: Adrenergic alpha-Antagonists; Benzofurans; Binding, Competitive; Cell Line; Cloning, Molecular; Humans; Imidazoles; Radioligand Assay; Receptor, Serotonin, 5-HT2B; Receptors, Serotonin; Serotonin Antagonists; Transfection; Tritium; Yohimbine	1998
Molecular cloning and pharmacological characterization of the guinea pig 5-HT1E receptor. European journal of pharmacology, 2004, Jan-26, Volume: 484, Issue:2-3 Topics: Amino Acid Sequence; Animals; Base Sequence; Brain; Chickens; Cloning, Molecular; Cricetinae; Dose-Response Relationship, Drug; Gerbillinae; Guinea Pigs; Haplorhini; Humans; Molecular Sequence Data; Protein Binding; Rabbits; Receptors, Serotonin; Serotonin Agents; Swine	2004
Investigations on the 1-(2-biphenyl)piperazine motif: identification of new potent and selective ligands for the serotonin(7) (5-HT(7)) receptor with agonist or antagonist action in vitro or ex vivo. Journal of medicinal chemistry, 2012, Jul-26, Volume: 55, Issue:14 Topics: Animals; Guinea Pigs; HeLa Cells; Humans; Ileum; Ligands; Models, Molecular; Molecular Weight; Piperazine; Piperazines; Protein Conformation; Receptors, Adrenergic, alpha-1; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Structure-Activity Relationship; Substrate Specificity	2012
Serotonin-antagonist effects of 1-(1-naphthyl)piperazine on operant behavior of squirrel monkeys. Neuropharmacology, 1989, Volume: 28, Issue:8 Topics: Animals; Conditioning, Operant; DOM 2,5-Dimethoxy-4-Methylamphetamine; Electroshock; Female; Food; Male; Piperazines; Quipazine; Reinforcement Schedule; Saimiri; Serotonin Antagonists	1989
Properties of some 1-arylpiperazines as antagonists of stereotyped behaviors mediated by central serotonergic receptors in rodents. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 247, Issue:3 Topics: Animals; Brain; Dose-Response Relationship, Drug; Male; Metergoline; Mice; Motor Activity; Piperazines; Rats; Receptors, Serotonin; Serotonin Antagonists; Stereotyped Behavior; Syndrome; Thiazolidines; Thyrotropin-Releasing Hormone	1988