1-(3-chlorophenyl)biguanide has been researched along with phenyl biguanide in 9 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 3 (33.33) | 18.2507 |
2000's | 4 (44.44) | 29.6817 |
2010's | 2 (22.22) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Abdel-Rahman, AA; Dukat, M; Glennon, RA; Gyermek, L; Ingher, S; Ismaiel, AM; Teitler, M | 1 |
Choi, YN; Du Pre, A; Dukat, M; Glennon, RA; Herrick-Davis, K; Smith, C; Teitler, M | 1 |
Kirschbaum, KS; Parihar, HS | 1 |
Daoud, MK; do Amaral, AT; Dukat, M; Glennon, RA; Herrick-Davis, K; Malvezzi, A; Purohit, A; Rahman, AA; Teitler, M | 1 |
Ji, Q; Peng, H; Qi, J; Yang, C; Zhou, Y; Zhu, Z | 1 |
Cichero, E; Espinoza, S; Gainetdinov, RR; Tonelli, M | 1 |
Burridge, J; Butler, A; Kilpatrick, GJ; Oxford, AW | 1 |
Higgins, GA; Joharchi, N; Sellers, EM | 1 |
Bartman, ME; Johnson, SM; Wilkerson, JE | 1 |
9 other study(ies) available for 1-(3-chlorophenyl)biguanide and phenyl biguanide
Article | Year |
---|---|
Structure-activity relationships for the binding of arylpiperazines and arylbiguanides at 5-HT3 serotonin receptors.
Topics: Animals; Biguanides; Heart Rate; Male; Molecular Structure; Muscle Contraction; Piperazines; Rabbits; Rats; Receptors, Serotonin; Reflex; Serotonin Antagonists; Serotonin Receptor Agonists; Structure-Activity Relationship; Urinary Bladder | 1996 |
The binding of arylguanidines at 5-HT(3) serotonin receptors: a structure-affinity investigation.
Topics: Animals; Guanidines; Hybrid Cells; Mice; Models, Molecular; Protein Binding; Radioligand Assay; Rats; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Serotonin Receptor Agonists; Structure-Activity Relationship; Substrate Specificity; Tumor Cells, Cultured | 2001 |
Electrostatic potential surfaces of 5-HT(3)R agonists suggest accessory cation-pi site adjacent to agonist binding domain.
Topics: Binding Sites; Electrochemistry; Electron Spin Resonance Spectroscopy; Guanidines; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Pyridines; Pyrroles; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Receptor Agonists | 2002 |
Conformationally-restricted analogues and partition coefficients of the 5-HT3 serotonin receptor ligands meta-chlorophenylbiguanide (mCPBG) and meta-chlorophenylguanidine (mCPG).
Topics: Biguanides; Chemical Phenomena; Chemistry, Physical; Guanidine; Ligands; Magnetic Resonance Spectroscopy; Molecular Conformation; Radioligand Assay; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Solubility; Structure-Activity Relationship | 2003 |
Discovery of small molecule inhibitors of integrin alphavbeta3 through structure-based virtual screening.
Topics: Biguanides; Binding Sites; Cations, Divalent; Databases, Factual; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Design; Drug Evaluation, Preclinical; Inhibitory Concentration 50; Integrin alphaVbeta3; Ligands; Structure-Activity Relationship | 2006 |
Novel biguanide-based derivatives scouted as TAAR1 agonists: Synthesis, biological evaluation, ADME prediction and molecular docking studies.
Topics: Absorption, Physicochemical; Animals; Biguanides; Chemistry Techniques, Synthetic; Computer Simulation; Drug Design; Humans; Mice; Molecular Docking Simulation; Protein Conformation; Receptors, G-Protein-Coupled; Structure-Activity Relationship | 2017 |
1-(m-chlorophenyl)-biguanide, a potent high affinity 5-HT3 receptor agonist.
Topics: Anesthesia; Animals; Biguanides; Binding, Competitive; Cats; Heart Rate; Imidazoles; In Vitro Techniques; Male; Ondansetron; Rats; Receptors, Serotonin; Reflex; Vagus Nerve | 1990 |
Behavioral effects of the 5-hydroxytryptamine3 receptor agonists 1-phenylbiguanide and m-chlorophenylbiguanide in rats.
Topics: Animals; Behavior, Animal; Biguanides; Conditioning, Psychological; Dopamine; Haloperidol; Indoles; Injections, Intraventricular; Male; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin Receptor Agonists; Tropisetron | 1993 |
5-HT3 receptor-dependent modulation of respiratory burst frequency, regularity, and episodicity in isolated adult turtle brainstems.
Topics: Action Potentials; Afferent Pathways; Animals; Biguanides; Dose-Response Relationship, Drug; Hypoglossal Nerve; In Vitro Techniques; Indoles; Physical Stimulation; Receptors, Serotonin, 5-HT3; Respiration; Respiratory Center; Serotonin 5-HT3 Receptor Agonists; Serotonin 5-HT3 Receptor Antagonists; Serotonin Agents; Time Factors; Tropanes; Tropisetron; Turtles | 2010 |