1-(3-chlorophenyl)biguanide and ondansetron

1-(3-chlorophenyl)biguanide has been researched along with ondansetron in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (24.00)18.2507
2000's15 (60.00)29.6817
2010's3 (12.00)24.3611
2020's1 (4.00)2.80

Authors

AuthorsStudies
Burridge, J; Butler, A; Kilpatrick, GJ; Oxford, AW1
Aulakh, CS; Mazzola-Pomietto, P; Murphy, DL1
Ali, Z; Barasi, S; Kozlov, A; Wu, G1
Hong, E; Meneses, A1
Callera, JC; Hamon, M; Laguzzi, R; Machado, BH; Sévoz, C1
Ellinwood, EH; King, GR; Xiong, Z1
Furuichi, K; Miyake, A; Mochizuki, S; Saito, M; Watanabe, T1
Eguchi, J; Inomata, Y; Saito, K1
Fenik, P; Ogawa, H; Veasey, SC1
Azevedo, MF; Bandeira, I; Carvalho, F; De Castro-e-Silva, E; Fregoneze, JB; Macêdo, D; Maldonado, I; Rocha, MA; Salles, L1
Arulmozhi, DK; Babu, RJ; Gupta, CN; Sridhar, N; Veeranjaneyulu, A1
Davies, PA; Hales, TG; Kirkness, EF; Safa, P; Stewart, A1
Chen, Y; Oatway, MA; Weaver, LC1
Cointeiro, C; de Castro e Silva, E; Faustino, TN; Ferreira, HS; Fregoneze, JB; Oliveira, E1
Ebert, B; Frederiksen, K; Jensen, TN; Nielsen, J1
de Castro e Silva, E; Fregoneze, JB; Luz, C; Reis, R; Souza, A1
Bae, HB; Choi, JI; Chung, ST; Kim, CM; Kim, SJ; Yoon, MH1
Jantos, H; Monti, JM1
Bohorquez, A; Hurley, LM1
Fukushima, T; Hori, Y; Ohtsubo, T; Tsuda, M; Yanagawa, Y1
Kondaurova, EM; Naumenko, VS; Popova, NK1
De Castro E Silva, E; Ferreira, HS; Fregoneze, JB; Oliveira, EF; Ribeiro, VF1
Fletcher, PJ; Limebeer, CL; Parker, LA; Tuerke, KJ1
Goel, RK; Mishra, A1
Baptista-de-Souza, D; Canto-de-Souza, A; Canto-de-Souza, L; de Souza, RR; Lopes, LT; Nunes-de-Souza, RL1

Other Studies

25 other study(ies) available for 1-(3-chlorophenyl)biguanide and ondansetron

ArticleYear
1-(m-chlorophenyl)-biguanide, a potent high affinity 5-HT3 receptor agonist.
    European journal of pharmacology, 1990, Jun-21, Volume: 182, Issue:1

    Topics: Anesthesia; Animals; Biguanides; Binding, Competitive; Cats; Heart Rate; Imidazoles; In Vitro Techniques; Male; Ondansetron; Rats; Receptors, Serotonin; Reflex; Vagus Nerve

1990
Temperature, food intake, and locomotor activity effects of a 5-HT3 receptor agonist and two 5-HT3 receptor antagonists in rats.
    Psychopharmacology, 1995, Volume: 121, Issue:4

    Topics: Animals; Biguanides; Body Temperature; Dose-Response Relationship, Drug; Eating; Locomotion; Male; Ondansetron; Rats; Rats, Wistar; Serotonin Antagonists; Serotonin Receptor Agonists; Tropanes

1995
The role of 5HT3 in nociceptive processing in the rat spinal cord: results from behavioural and electrophysiological studies.
    Neuroscience letters, 1996, Apr-26, Volume: 208, Issue:3

    Topics: Animals; Biguanides; Indoles; Male; Microinjections; Ondansetron; Pain Measurement; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spinal Cord; Time Factors; Tropisetron

1996
Systemic injection of p-chloroamphetamine eliminates the effect of the 5-HT3 compounds on learning.
    Pharmacology, biochemistry, and behavior, 1996, Volume: 53, Issue:4

    Topics: Animals; Association Learning; Behavior, Animal; Biguanides; Conditioning, Operant; Indoles; Learning; Male; Ondansetron; p-Chloroamphetamine; Rats; Rats, Wistar; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists; Tropisetron

1996
Role of serotonin3 receptors in the nucleus tractus solitarii on the carotid chemoreflex.
    The American journal of physiology, 1997, Volume: 272, Issue:3 Pt 2

    Topics: Animals; Atropine; Benzamides; Biguanides; Brain Mapping; Bridged Bicyclo Compounds, Heterocyclic; Carotid Body; Chemoreceptor Cells; Heart Rate; Kynurenic Acid; Male; Microinjections; Ondansetron; Potassium Cyanide; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Reflex; Respiration; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Solitary Nucleus; Sympathetic Nervous System; Tidal Volume; Vagus Nerve

1997
Blockade of accumbens 5-HT3 receptor down-regulation by ondansetron administered during continuous cocaine administration.
    European journal of pharmacology, 1999, Jan-08, Volume: 364, Issue:2-3

    Topics: Analysis of Variance; Animals; Biguanides; Brain; Calcium; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Down-Regulation; In Vitro Techniques; Infusion Pumps; Injections, Subcutaneous; Male; Ondansetron; Potassium; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Serotonin Receptor Agonists

1999
Cloning, expression, and characterization of ferret 5-HT(3) receptor subunit.
    European journal of pharmacology, 2000, Jul-07, Volume: 399, Issue:2-3

    Topics: Alternative Splicing; Amino Acid Sequence; Animals; Biguanides; Binding, Competitive; Cell Line; Cloning, Molecular; DNA, Complementary; Dose-Response Relationship, Drug; Electrophysiology; Ferrets; Gene Expression; Humans; Imidazoles; Indoles; Kruppel-Like Factor 6; Kruppel-Like Transcription Factors; Membrane Potentials; Molecular Sequence Data; Ondansetron; Piperazines; Proto-Oncogene Proteins; Radioligand Assay; Rats; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; RNA, Messenger; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tissue Distribution; Trans-Activators; Tritium; Tubocurarine

2000
The anxiolytic-like effect of MCI-225, a selective NA reuptake inhibitor with 5-HT3 receptor antagonism.
    Pharmacology, biochemistry, and behavior, 2001, Volume: 68, Issue:4

    Topics: Adrenergic Uptake Inhibitors; Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Biguanides; Male; Norepinephrine; Ondansetron; Piperazines; Psychotropic Drugs; Pyrimidines; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Serotonin Receptor Agonists

2001
Hypoglossal nerve response to 5-HT3 drugs injected into the XII nucleus and vena cava in the rat.
    Sleep, 2001, Dec-15, Volume: 24, Issue:8

    Topics: Animals; Biguanides; Hypoglossal Nerve; Injections, Intravenous; Male; Microinjections; Motor Neurons; Nodose Ganglion; Ondansetron; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Serotonin Receptor Agonists; Sleep Apnea, Obstructive; Sleep, REM; Venae Cavae

2001
Central 5-HT3 receptor stimulation by m-CPBG increases blood glucose in rats.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2002, Volume: 34, Issue:2

    Topics: Animals; Biguanides; Blood Glucose; Fasting; Food; Injections, Intraventricular; Kinetics; Male; Ondansetron; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Restraint, Physical; Serotonin Antagonists; Serotonin Receptor Agonists; Stress, Physiological

2002
5-HT3 receptors in selective animal models of cognition.
    Indian journal of experimental biology, 2002, Volume: 40, Issue:2

    Topics: Animals; Biguanides; Cognition; Ligands; Male; Maze Learning; Mice; Ondansetron; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Scopolamine; Serotonin Antagonists; Signal Transduction

2002
Introduction of the 5-HT3B subunit alters the functional properties of 5-HT3 receptors native to neuroblastoma cells.
    Neuropharmacology, 2003, Volume: 44, Issue:2

    Topics: Animals; Biguanides; Calcium; Cell Differentiation; Cell Line; Dose-Response Relationship, Drug; Drug Interactions; Fluorescence; Gene Expression; Green Fluorescent Proteins; Luminescent Proteins; Mice; Molecular Sequence Data; Neuroblastoma; Ondansetron; Patch-Clamp Techniques; Protein Subunits; Rats; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Recombinant Fusion Proteins; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Transfection

2003
The 5-HT3 receptor facilitates at-level mechanical allodynia following spinal cord injury.
    Pain, 2004, Volume: 110, Issue:1-2

    Topics: 5,6-Dihydroxytryptamine; Animals; Behavior, Animal; Biguanides; Dose-Response Relationship, Drug; Drug Interactions; Escape Reaction; Hyperesthesia; Immunohistochemistry; Male; Methysergide; Neurotoxins; Ondansetron; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Wistar; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spinal Cord Injuries; Time Factors

2004
Role of central 5-HT3 receptors in the control of blood pressure in stressed and non-stressed rats.
    Brain research, 2004, Nov-26, Volume: 1028, Issue:1

    Topics: Adaptation, Physiological; Animals; Biguanides; Blood Pressure; Brain; Heart Rate; Injections, Intraventricular; Male; Ondansetron; Rats; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Stress, Psychological

2004
Molecular cloning and pharmacological characterization of serotonin 5-HT(3A) receptor subtype in dog.
    European journal of pharmacology, 2006, May-24, Volume: 538, Issue:1-3

    Topics: Amino Acid Sequence; Animals; Biguanides; Cloning, Molecular; DNA, Complementary; Dogs; Dose-Response Relationship, Drug; Female; Membrane Potentials; Molecular Sequence Data; Mutation; Ondansetron; Oocytes; Receptors, Serotonin, 5-HT3; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Xenopus

2006
Role of 5-HT3 and 5-HT2C receptors located within the medial amygdala in the control of salt intake in sodium-depleted rats.
    Brain research, 2006, Jul-12, Volume: 1099, Issue:1

    Topics: Amygdala; Analysis of Variance; Animals; Avoidance Learning; Behavior, Animal; Biguanides; Dose-Response Relationship, Drug; Drinking; Drug Interactions; Feeding Behavior; Furosemide; Male; Ondansetron; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin, 5-HT3; Renal Insufficiency; Saccharin; Serotonin Antagonists; Serotonin Receptor Agonists; Sodium; Time Factors

2006
Lack of reciprocity between opioid and 5-HT3 receptors for antinociception in rat spinal cord.
    Pharmacology, 2006, Volume: 77, Issue:4

    Topics: Analgesia; Analgesics, Opioid; Animals; Biguanides; Dose-Response Relationship, Drug; Formaldehyde; Hindlimb; Indazoles; Injections, Spinal; Male; Morphine; Motor Activity; Muscle Tonus; Naloxone; Narcotic Antagonists; Ondansetron; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Receptors, Serotonin, 5-HT3; Serotonin 5-HT3 Receptor Antagonists; Serotonin Receptor Agonists; Spinal Cord; Tropanes

2006
Activation of the serotonin 5-HT3 receptor in the dorsal raphe nucleus suppresses REM sleep in the rat.
    Progress in neuro-psychopharmacology & biological psychiatry, 2008, May-15, Volume: 32, Issue:4

    Topics: Animals; Biguanides; Depression, Chemical; Electroencephalography; Injections, Intraventricular; Male; Ondansetron; Raphe Nuclei; Rats; Rats, Wistar; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Serotonin Receptor Agonists; Sleep Stages; Sleep, REM

2008
Activation of serotonin 3 receptors changes in vivo auditory responses in the mouse inferior colliculus.
    Hearing research, 2009, Volume: 251, Issue:1-2

    Topics: Acoustic Stimulation; Action Potentials; Animals; Biguanides; Bridged Bicyclo Compounds, Heterocyclic; Electrophysiology; Inferior Colliculi; Male; Mice; Mice, Inbred CBA; Neurons; Ondansetron; Oxazines; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin 5-HT3 Receptor Agonists; Serotonin 5-HT3 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists

2009
Facilitatory actions of serotonin type 3 receptors on GABAergic inhibitory synaptic transmission in the spinal superficial dorsal horn.
    Journal of neurophysiology, 2009, Volume: 102, Issue:3

    Topics: Analysis of Variance; Animals; Biguanides; gamma-Aminobutyric Acid; Gene Expression Regulation; Glutamate Decarboxylase; Green Fluorescent Proteins; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Male; Mice; Mice, Transgenic; Models, Biological; Neural Inhibition; Ondansetron; Patch-Clamp Techniques; Posterior Horn Cells; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin 5-HT3 Receptor Agonists; Serotonin Antagonists; Serotonin Receptor Agonists; Spinal Cord; Synaptic Transmission

2009
Central 5-HT3 receptor-induced hypothermia in mice: interstrain differences and comparison with hypothermia mediated via 5-HT1A receptor.
    Neuroscience letters, 2009, Nov-06, Volume: 465, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Biguanides; Blood-Brain Barrier; Body Temperature; Dose-Response Relationship, Drug; Hypothermia; Male; Mice; Mice, Inbred Strains; Ondansetron; Piperazines; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin, 5-HT3; Serotonin 5-HT1 Receptor Antagonists; Serotonin 5-HT3 Receptor Agonists; Serotonin Antagonists; Serotonin Receptor Agonists; Species Specificity

2009
Multiple opioid receptors mediate the hypotensive response induced by central 5-HT(3) receptor stimulation.
    Neuropeptides, 2011, Volume: 45, Issue:3

    Topics: Animals; Biguanides; Blood Pressure; Heart Rate; Hypotension; Male; Naloxone; Naltrexone; Narcotic Antagonists; Ondansetron; Rats; Rats, Wistar; Receptors, Opioid; Receptors, Serotonin, 5-HT3; Serotonin 5-HT3 Receptor Agonists; Serotonin 5-HT3 Receptor Antagonists

2011
Double dissociation between regulation of conditioned disgust and taste avoidance by serotonin availability at the 5-HT(3) receptor in the posterior and anterior insular cortex.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, Oct-03, Volume: 32, Issue:40

    Topics: 5,6-Dihydroxytryptamine; Animals; Avoidance Learning; Biguanides; Cerebral Cortex; Conditioning, Classical; Emotions; Lithium Chloride; Male; Nausea; Ondansetron; Rats; Rats, Sprague-Dawley; Receptors, Serotonin, 5-HT3; Saccharin; Serotonin 5-HT3 Receptor Agonists; Serotonin 5-HT3 Receptor Antagonists; Taste

2012
Chronic 5-HT
    Neuroscience, 2016, Dec-17, Volume: 339

    Topics: Animals; Anticonvulsants; Biguanides; Cerebral Cortex; Dose-Response Relationship, Drug; Hippocampus; Kindling, Neurologic; Male; Memory; Memory Disorders; Mice; Nootropic Agents; Ondansetron; Pentylenetetrazole; Random Allocation; Receptors, Serotonin, 5-HT3; Seizures; Serotonin 5-HT3 Receptor Antagonists; Serotonin Receptor Agonists

2016
The interplay between 5-HT
    Behavioural brain research, 2022, 01-24, Volume: 417

    Topics: Animals; Anxiety; Behavior, Animal; Biguanides; Male; Mice; Ondansetron; Periaqueductal Gray; Piperazines; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin, 5-HT3; Serotonin

2022