1-(3-chlorophenyl)biguanide has been researched along with biguanides in 128 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 53 (41.41) | 18.2507 |
| 2000's | 46 (35.94) | 29.6817 |
| 2010's | 28 (21.88) | 24.3611 |
| 2020's | 1 (0.78) | 2.80 |
| Authors | Studies |
|---|---|
| Boess, FG; Lummis, SC; Martin, IL; Sepúlveda, MI | 1 |
| Lummis, SC; Martin, IL; Sepúlveda, MI | 1 |
| Burridge, J; Butler, A; Kilpatrick, GJ; Oxford, AW | 1 |
| Calvi, C; Ellinwood, EH; King, GR; Xue, Z | 1 |
| Bagdy, G; Burrello, N; Calogero, AE; D'Agata, R; Polosa, P | 1 |
| Altier, H; Jantos, H; Monti, D; Monti, JM; Ponzoni, A | 1 |
| Campbell, AD; McBride, WJ | 1 |
| Walcourt-Ambakederemo, A; Winlow, W | 1 |
| Bare, DJ; Ghetti, B; Richter, JA; Simon, JR; Yu, H | 1 |
| Hargreaves, AC; Lummis, SC; Taylor, CW | 1 |
| Detzner, M; Exner, HJ; Göthert, M; Kathmann, M; Schlicker, E | 1 |
| Martín, ML; Morán, A; San Román, L; Velasco, C | 1 |
| Barnes, NM; Kilpatrick, GJ; Steward, LJ; West, KE | 1 |
| Baker, J; Kilpatrick, GJ; Lummis, SC; Sepúlveda, MI | 1 |
| Jantos, H; Monti, JM; Ponzoni, A | 1 |
| Jeffrey, JJ; Rydelek-Fitzgerald, L; Teitler, M; Wilcox, BD | 1 |
| Ito, H; Kamato, T; Miyata, K; Nagakura, Y; Nishida, A; Yamano, M; Yuki, H | 1 |
| Higgins, GA; Joharchi, N; Sellers, EM | 1 |
| Campbell, AD; Simon, JR; Womer, DE | 1 |
| Deutsch, SI; Koetzner, L; Mastropaolo, J | 1 |
| Aulakh, CS; Mazzola-Pomietto, P; Murphy, DL | 1 |
| Bartrup, JT; Newberry, NR | 1 |
| Ali, Z; Barasi, S; Kozlov, A; Wu, G | 1 |
| Ito, H; Kamato, T; Miyata, K; Nagakura, Y; Nishida, A; Yamano, M | 1 |
| Callera, JC; Hamon, M; Laguzzi, R; Machado, B; Nosjean, A; Sévoz, C | 1 |
| Hong, E; Meneses, A | 1 |
| Bienkowski, P; Kostowski, W; Stefanski, R | 1 |
| Gunthorpe, MJ; Hargreaves, AC; Lummis, SC; Taylor, CW | 1 |
| Callera, JC; Hamon, M; Laguzzi, R; Machado, BH; Sévoz, C | 1 |
| King, GR; Matell, MS | 1 |
| Ito, H; Kamato, T; Miyata, K; Nagakura, Y; Nishida, A | 1 |
| Koshino, Y; Nakamura, M; Shiraishi, J; Wada, Y | 1 |
| Kreikamp, AP; van Hooft, JA; Vijverberg, HP | 1 |
| Alloui, A; Bardin, L; Eschalier, A; Jourdan, D; Lavarenne, J | 1 |
| Caldarola-Pastuszka, M; Maswood, N; Uphouse, L | 2 |
| Bienkowski, P; Koros, E; Kostowski, W; Piasecki, J | 1 |
| Nichols, RA; Rondé, P | 3 |
| Hamon, M; Laguzzi, R; Nosjean, A | 1 |
| Lummis, SC; Niemeyer, MI | 1 |
| Franc, B; Hamon, M; Laguzzi, R; Nosjean, A; Sévoz-Couche, C | 1 |
| Ishima, T; Nakagawa, Y; Takashima, T | 1 |
| Bienkowski, P; Iwinska, K; Koros, E; Kostowski, W; Panocka, I; Piasecki, J | 1 |
| Bienkowski, P; Kostowski, W | 1 |
| Ellinwood, EH; King, GR; Xiong, Z | 2 |
| Banchero, P; Jantos, H; Lagos, P; Monti, JM; Ponzoni, A; Silveira, R | 1 |
| Furuichi, K; Miyake, A; Mochizuki, S | 1 |
| Asghar, AU; Khasabov, SG; King, AE; Lopez-Garcia, JA | 1 |
| Goldberg, SR; Kutkat, SW; Laufert, MD; Munzar, P; Nováková, J | 1 |
| D'Andrea, MR; Dubin, AE; Erlander, MG; Galindo, JE; Glass, CA; Huvar, R; Jackson, MR; Joy, KC; Lovenberg, TW; Luo, L; Pyati, J; Wilson, SJ; Zhu, JY | 1 |
| Nakagawa, Y; Sasaki, A; Takashima, T | 1 |
| Lummis, SC; Spier, AD | 1 |
| Furuichi, K; Miyake, A; Mochizuki, S; Saito, M; Watanabe, T | 1 |
| Fernández, MM; Martín, ML; Morán, A; San Román, L | 1 |
| Bonagamba, LG; Callera, J; Hamon, M; Laguzzi, R; Machado, BH; N'Diaye, A; Sévoz-Couche, C; Uygun-Louvet, K | 1 |
| Lummis, SC; Nayak, SV; Nichols, RA; Rondé, P; Spier, AD | 1 |
| Akaike, N; Koyama, S; Kubo, C; Matsumoto, N | 1 |
| Akuzawa, S; Ito, H; Iwaoka, K; Kamato, T; Kiso, T; Miyata, K; Nagakura, Y; Naitoh, Y; Sakai, H; Suzuki, M; Yamaguchi, T; Yamano, M; Yuki, H | 1 |
| Garraway, SM; Hochman, S | 1 |
| Eguchi, J; Inomata, Y; Saito, K | 1 |
| Fenik, P; Ogawa, H; Veasey, SC | 1 |
| Azevedo, MF; Bandeira, I; Carvalho, F; De Castro-e-Silva, E; Fregoneze, JB; Macêdo, D; Maldonado, I; Rocha, MA; Salles, L | 1 |
| Hamon, M; Laguzzi, R; Maisonneuve, B; Sévoz-Couche, C | 1 |
| Bonagamba, L; Callera, JC; Hamon, M; Laguzzi, R; Machado, B; Nosjean, A | 1 |
| Awe, SO; Harris, LC; LeDay, AM; Ohia, SE; Opere, CA; Sharif, NA | 1 |
| Morales, M; Oz, M; Zhang, L | 1 |
| Campos, I; Castro, L; De Castro-e-Silva, E; Duque, B; Fregoneze, J; Maldonado, I; Reis de Oliveira, I; Varjão, B | 1 |
| Arulmozhi, DK; Babu, RJ; Gupta, CN; Sridhar, N; Veeranjaneyulu, A | 1 |
| Davies, PA; Hales, TG; Kirkness, EF; Safa, P; Stewart, A | 1 |
| Daoud, MK; do Amaral, AT; Dukat, M; Glennon, RA; Herrick-Davis, K; Malvezzi, A; Purohit, A; Rahman, AA; Teitler, M | 1 |
| Garrelds, IM; Meijssen, MA; van Meeteren, ME; Zijlstra, FJ | 1 |
| Angelo, AL; Athanazio, R; Barbetta, M; Campos, I; Castro, L; de Castro e Silva, E; Ferreira, H; Fregoneze, J; Ramos, AC; Varjão, B | 1 |
| Jones, RL; Kan, KK; Ngan, MP; Rudd, JA | 1 |
| Chen, Y; Oatway, MA; Weaver, LC | 1 |
| Alloui, A; Bonnefont, J; Bourinet, E; Doucet, E; Eschalier, A; Hamon, M; Libert, F; Nargeot, J | 1 |
| Knyshevski, I; Melloni, RH; Ricci, LA | 1 |
| Cointeiro, C; de Castro e Silva, E; Faustino, TN; Ferreira, HS; Fregoneze, JB; Oliveira, E | 1 |
| Luebke, JI; Mokler, DJ; Turner, TJ | 1 |
| Asgari, K; Body, S; Bradshaw, CM; Fone, KC; Rickard, JF; Szabadi, E; Zhang, Z | 2 |
| Höglund, AU; Kommalage, M | 1 |
| Bikádi, Z; Gaines, C; Joshi, PR; Kulkarni, TR; Mani, M; Schulte, MK; Suryanarayanan, A | 1 |
| Quirk, PL; Siegel, RE | 1 |
| Ebert, B; Frederiksen, K; Jensen, TN; Nielsen, J | 1 |
| de Castro e Silva, E; Fregoneze, JB; Luz, C; Reis, R; Souza, A | 1 |
| Liu, W; McBride, WJ; Thielen, RJ | 1 |
| Bae, HB; Choi, JI; Chung, ST; Kim, CM; Kim, SJ; Yoon, MH | 1 |
| Bostock, H; Grafe, P; Lang, PM; Moalem-Taylor, G; Tracey, DJ | 1 |
| Bell, RL; Gryszowka, VE; Ji, D; McBride, WJ; Oster, SM; Rodd, ZA; Toalston, JE | 1 |
| Liu, W; McBride, WJ; Rodd, ZA; Thielen, RJ | 1 |
| Jantos, H; Monti, JM | 1 |
| Bohorquez, A; Hurley, LM | 1 |
| Fukushima, T; Hori, Y; Ohtsubo, T; Tsuda, M; Yanagawa, Y | 1 |
| Aliczki, M; Halasz, J; Haller, J; Mikics, E; Vas, J | 1 |
| Dougherty, JJ; Nichols, RA | 1 |
| Kondaurova, EM; Naumenko, VS; Popova, NK | 2 |
| Bagdy, G; Balogh, B; Gyongyosi, N; Katai, Z; Laufer, R; Molnar, E; Tekes, K | 1 |
| Bahremand, A; Daneshmand, A; Dehpour, AR; Fakhfouri, G; Mehr, SE; Mousavizadeh, K; Rahimian, R; Rasouli, MR | 1 |
| Bartman, ME; Johnson, SM; Wilkerson, JE | 1 |
| Barzegar-Fallah, A; Daneshmand, A; Dehpour, AR; Fakhfouri, G; Mehr, SE; Mohammadi-Rick, S; Rahimian, R; Shabanzadeh, AP | 1 |
| Catenaccio, V; Jantos, H; Monti, JM; Xavier, S | 1 |
| De Castro E Silva, E; Ferreira, HS; Fregoneze, JB; Oliveira, EF; Ribeiro, VF | 1 |
| Bahremand, A; Dehpour, AR; Ebrahimi, A; Fakhfouri, G; Ghasemi, A; Ghasemi, M; Loloee, S; Payandemehr, B; Pourmand, N; Rahimian, R; Ziai, P | 1 |
| Charles, PD; Parkavi, A; Rajan, KE; Singh, HK | 1 |
| Khramova, GM; Kozyreva, TV; Naumenko, VS; Popova, NK; Voronova, IP | 1 |
| Guo, F; Guo, HC; Li, WY; Liu, X; Shi, XL; Su, SW; Wang, YL; Zhang, LN | 1 |
| Hirata, T; Keto, Y; Seki, N; Sengoku, T; Yamano, M; Yokoyama, T | 1 |
| Amouzegar, A; Bahremand, A; Dehpour, AR; Payandemehr, B; Rahimian, R; Sharifzadeh, M; Ziai, P | 1 |
| Fletcher, PJ; Limebeer, CL; Parker, LA; Tuerke, KJ | 1 |
| Bower, KS; Dougherty, DA; Lester, HA; Miles, TF | 1 |
| Aminian, A; Dehpour, AR; Ghazi-Khansari, M; Hassanzadeh, G; Javadi, S; Kafami, L; Mehr, SE; Noorbakhsh, F; Rahimian, R | 1 |
| Dunn, SM; Kozuska, JL; Martin, IL; Michaelson, SD; Paulsen, IM | 1 |
| Hirata, T; Keto, Y; Nakata-Fukuda, M; Uchiyama, Y; Yamano, M; Yokoyama, T | 1 |
| Eppolito, AK; Gerak, LR; Kodeih, HR | 1 |
| Dougherty, DA; Lester, HA; Miles, TF | 1 |
| Kafi, F; Khakpai, F; Nasehi, M; Zarrindast, MR | 1 |
| Baptista-Hon, DT; Hales, TG; Lovinger, DM; Morton, RA | 1 |
| Gupta, D; Radhakrishnan, M; Thangaraj, D | 1 |
| Ahmadi-Mahmoodabadi, N; Emam Ghoreishi, M; Nasehi, M; Zarrindast, MR | 1 |
| Goel, RK; Mishra, A | 1 |
| Hirayama, Y; Lummis, SCR; Price, KL | 1 |
| Algazo, M; Alshaib, H; Amiri Gheshlaghi, S; Dehpour, AR; Mohammad Jafari, R; Rahimi, N | 1 |
| Bogart, LJ; Hensch, TK; Lichtman, JW; Takesian, AE | 1 |
| Baptista-de-Souza, D; Canto-de-Souza, A; Canto-de-Souza, L; de Souza, RR; Lopes, LT; Nunes-de-Souza, RL | 1 |
128 other study(ies) available for 1-(3-chlorophenyl)biguanide and biguanides
| Article | Year |
|---|---|
5-HT3 receptors in NG108-15 neuroblastoma x glioma cells: effect of the novel agonist 1-(m-chlorophenyl)-biguanide.
Topics: Animals; Biguanides; Binding, Competitive; Evoked Potentials; Glioma; Hybrid Cells; Imidazoles; Indoles; Kinetics; Mice; Neuroblastoma; Rats; Receptors, Serotonin; Serotonin; Serotonin Antagonists | 1992 |
The agonist properties of m-chlorophenylbiguanide and 2-methyl-5-hydroxytryptamine on 5-HT3 receptors in N1E-115 neuroblastoma cells.
Topics: Animals; Biguanides; Membrane Potentials; Mice; Neuroblastoma; Neurons; Radioligand Assay; Receptors, Serotonin; Serotonin; Tumor Cells, Cultured | 1991 |
1-(m-chlorophenyl)-biguanide, a potent high affinity 5-HT3 receptor agonist.
Topics: Anesthesia; Animals; Biguanides; Binding, Competitive; Cats; Heart Rate; Imidazoles; In Vitro Techniques; Male; Ondansetron; Rats; Receptors, Serotonin; Reflex; Vagus Nerve | 1990 |
5-HT3 agonist-induced dopamine overflow during withdrawal from continuous or intermittent cocaine administration.
Topics: Animals; Biguanides; Cocaine; Corpus Striatum; Male; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Receptor Agonists | 1995 |
Role for serotonin3 receptors in the control of adrenocorticotropic hormone release from rat pituitary cell cultures.
Topics: Adrenocorticotropic Hormone; Animals; Arginine Vasopressin; Biguanides; Cells, Cultured; Corticotropin-Releasing Hormone; Dose-Response Relationship, Drug; Male; Pituitary Gland; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 1995 |
Increased waking after intra-accumbens injection of m-chlorophenylbiguanide: prevention with serotonin or dopamine receptor antagonists.
Topics: Animals; Benzamides; Benzazepines; Biguanides; Dopamine Antagonists; Injections; Male; Nucleus Accumbens; Rats; Rats, Wistar; Serotonin Antagonists; Serotonin Receptor Agonists; Sleep; Sleep, REM; Tropanes; Wakefulness | 1995 |
Serotonin-3 receptor and ethanol-stimulated dopamine release in the nucleus accumbens.
Topics: Animals; Biguanides; Calcium; Chromatography, High Pressure Liquid; Dopamine; Electrochemistry; Ethanol; Extracellular Space; Female; Indoles; Microdialysis; Nucleus Accumbens; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin Antagonists; Tropisetron | 1995 |
5-HT receptors on identified Lymnaea neurones in culture: pharmacological characterization of 5-HT3 receptors.
Topics: Animals; Biguanides; Cells, Cultured; Ketanserin; Lymnaea; Neurons; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tropanes | 1995 |
Dopamine transporter-dependent and -independent endogenous dopamine release from weaver mouse striatum in vitro.
Topics: Animals; Biguanides; Carrier Proteins; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Female; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Mutant Strains; Nerve Tissue Proteins; Nomifensine; Potassium; Serotonin; Serotonin Antagonists; Veratridine | 1995 |
Ca2+ permeability of cloned and native 5-hydroxytryptamine type 3 receptors.
Topics: Biguanides; Calcium; Calcium Channels; Cell Line; Cloning, Molecular; Humans; Membrane Potentials; Permeability; Receptors, Serotonin; Serotonin Receptor Agonists; Tumor Cells, Cultured | 1994 |
The 5-HT3 receptor agonist 1-(m-chlorophenyl)-biguanide facilitates noradrenaline release by blockade of alpha 2-adrenoceptors in the mouse brain cortex.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Biguanides; Cerebral Cortex; Kinetics; Male; Mice; Mice, Inbred Strains; Norepinephrine; Receptors, Adrenergic, alpha-2; Serotonin Receptor Agonists; Tritium; Yohimbine | 1994 |
Pharmacological characterization of 5-HT receptors in parasympathetic innervation of rat heart.
Topics: Acetylcholine; Animals; Biguanides; Blood Pressure; Decerebrate State; Electric Stimulation; Heart; Heart Rate; Male; Parasympathetic Nervous System; Piperazines; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Vagus Nerve | 1994 |
Labelling of 5-HT3 receptor recognition sites in the rat brain using the agonist radioligand [3H]meta-chlorophenylbiguanide.
Topics: Animals; Autoradiography; Benzamides; Biguanides; Binding Sites; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Female; Radioligand Assay; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin Antagonists; Tissue Distribution; Tritium | 1993 |
Characterization of [3H]meta-chlorophenylbiguanide binding to 5-HT3 receptors in N1E-115 neuroblastoma cells.
Topics: Animals; Biguanides; Binding, Competitive; Electrophysiology; Mice; Neuroblastoma; Radioligand Assay; Receptors, Serotonin; Tritium; Tumor Cells, Cultured | 1993 |
The effects of selective activation of the 5-HT3 receptor with m-chlorophenylbiguanide on sleep and wakefulness in the rat.
Topics: Animals; Biguanides; Injections, Intraventricular; Injections, Subcutaneous; Male; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sleep; Sleep, REM; Tropanes; Wakefulness | 1993 |
Serotonin-mediated 5-HT2 receptor gene regulation in rat myometrial smooth muscle cells.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Biguanides; Cells, Cultured; Cycloheximide; Female; Gene Expression Regulation; Ketanserin; Medroxyprogesterone Acetate; Myometrium; Piperazines; Quipazine; Rats; Receptors, Serotonin; RNA, Messenger; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiperone; Sulpiride; Transcription, Genetic; Up-Regulation | 1993 |
Mechanisms of cisplatin- and m-chlorophenylbiguanide-induced emesis in ferrets.
Topics: Animals; Benzimidazoles; Biguanides; Cisplatin; Dose-Response Relationship, Drug; Ferrets; Injections, Intravenous; Injections, Intraventricular; Male; Receptors, Serotonin; Serotonin Antagonists; Splanchnic Nerves; Vagotomy; Vagus Nerve; Vomiting | 1993 |
Behavioral effects of the 5-hydroxytryptamine3 receptor agonists 1-phenylbiguanide and m-chlorophenylbiguanide in rats.
Topics: Animals; Behavior, Animal; Biguanides; Conditioning, Psychological; Dopamine; Haloperidol; Indoles; Injections, Intraventricular; Male; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin Receptor Agonists; Tropisetron | 1993 |
The 5-HT3 receptor agonist 1-(m-chlorophenyl)-biguanide interacts with the dopamine transporter in rat brain synaptosomes.
Topics: Analysis of Variance; Animals; Biguanides; Binding, Competitive; Biological Transport, Active; Brain; Carrier Proteins; Caudate Nucleus; Cell Membrane; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Female; In Vitro Techniques; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Nucleus Accumbens; Rats; Rats, Wistar; Serotonin Antagonists; Synaptosomes | 1995 |
Facilitating role of m-chlorophenylbiguanide in a cocaine discrimination.
Topics: Animals; Behavior, Animal; Biguanides; Cocaine; Discrimination Learning; Dose-Response Relationship, Drug; Male; Rats; Rats, Sprague-Dawley; Serotonin Receptor Agonists | 1995 |
Temperature, food intake, and locomotor activity effects of a 5-HT3 receptor agonist and two 5-HT3 receptor antagonists in rats.
Topics: Animals; Biguanides; Body Temperature; Dose-Response Relationship, Drug; Eating; Locomotion; Male; Ondansetron; Rats; Rats, Wistar; Serotonin Antagonists; Serotonin Receptor Agonists; Tropanes | 1995 |
Electrophysiological consequences of ligand binding to the desensitized 5-HT3 receptor in mammalian NG108-15 cells.
Topics: Animals; Biguanides; Binding, Competitive; Cells, Cultured; Dose-Response Relationship, Drug; Membrane Potentials; Mice; Patch-Clamp Techniques; Rats; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists; Tubocurarine | 1996 |
The role of 5HT3 in nociceptive processing in the rat spinal cord: results from behavioural and electrophysiological studies.
Topics: Animals; Biguanides; Indoles; Male; Microinjections; Ondansetron; Pain Measurement; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spinal Cord; Time Factors; Tropisetron | 1996 |
Characterization of 5-hydroxytryptamine (5-HT) receptor subtypes influencing colonic motility in conscious dogs.
Topics: 4-Aminobenzoic Acid; Animals; Benzamides; Benzimidazoles; Biguanides; Bridged Bicyclo Compounds, Heterocyclic; Colon; Dogs; Dose-Response Relationship, Drug; Gastrointestinal Motility; Hexamethonium; Injections, Intravenous; Ketanserin; Male; Methysergide; Muscle Contraction; Muscle, Smooth; para-Aminobenzoates; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Structure-Activity Relationship; Transducers | 1996 |
Stimulation of 5-HT3 receptors in the NTS inhibits the cardiac Bezold-Jarisch reflex response.
Topics: Animals; Biguanides; Blood Pressure; GABA Antagonists; Heart; Heart Conduction System; Male; Microinjections; Neural Inhibition; Pressoreceptors; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Reflex; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Solitary Nucleus; Sympathetic Nervous System; Vagus Nerve | 1996 |
Systemic injection of p-chloroamphetamine eliminates the effect of the 5-HT3 compounds on learning.
Topics: Animals; Association Learning; Behavior, Animal; Biguanides; Conditioning, Operant; Indoles; Learning; Male; Ondansetron; p-Chloroamphetamine; Rats; Rats, Wistar; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists; Tropisetron | 1996 |
Studies on the role of 5-HT3 receptors in the mediation of the ethanol interoceptive cue.
Topics: Animals; Behavior, Animal; Biguanides; Discrimination, Psychological; Dose-Response Relationship, Drug; Ethanol; Injections, Intraperitoneal; Injections, Intraventricular; Male; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin Receptor Agonists | 1996 |
Direct inhibition of 5-hydroxytryptamine3 receptors by antagonists of L-type Ca2+ channels.
Topics: Biguanides; Binding, Competitive; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Electrophysiology; Fura-2; Granisetron; Humans; Kidney; Kinetics; Microscopy, Video; Neuroblastoma; Nimodipine; Radioligand Assay; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Serotonin Receptor Agonists; Tritium; Tumor Cells, Cultured; Verapamil | 1996 |
Role of serotonin3 receptors in the nucleus tractus solitarii on the carotid chemoreflex.
Topics: Animals; Atropine; Benzamides; Biguanides; Brain Mapping; Bridged Bicyclo Compounds, Heterocyclic; Carotid Body; Chemoreceptor Cells; Heart Rate; Kynurenic Acid; Male; Microinjections; Ondansetron; Potassium Cyanide; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Reflex; Respiration; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Solitary Nucleus; Sympathetic Nervous System; Tidal Volume; Vagus Nerve | 1997 |
5-HT3 receptor mediated dopamine release in the nucleus accumbens during withdrawal from continuous cocaine.
Topics: Animals; Biguanides; Cocaine; Dopamine; Male; Narcotics; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Antagonists; Substance Withdrawal Syndrome | 1997 |
Effect of a selective 5-HT3 receptor agonist on gastric motility in fasted and fed dogs.
Topics: Animals; Benzimidazoles; Biguanides; Dogs; Fasting; Gastrointestinal Motility; Male; Serotonin Receptor Agonists; Stomach; Time Factors | 1997 |
Effects of the 5-HT3 receptor agonist 1-(m-chlorophenyl)-biguanide in the rat kindling model of epilepsy.
Topics: Amygdala; Animals; Biguanides; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy; Kindling, Neurologic; Male; Rats; Rats, Wistar; Serotonin Receptor Agonists | 1997 |
Native serotonin 5-HT3 receptors expressed in Xenopus oocytes differ from homopentameric 5-HT3 receptors.
Topics: Animals; Biguanides; Cell Differentiation; Dopamine; Female; Kinetics; Macromolecular Substances; Membrane Potentials; Mice; Neuroblastoma; Oocytes; Patch-Clamp Techniques; Plasmids; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; RNA, Messenger; Serotonin; Serotonin Receptor Agonists; Tumor Cells, Cultured; Xenopus | 1997 |
Differential influence of two serotonin 5-HT3 receptor antagonists on spinal serotonin-induced analgesia in rats.
Topics: Animals; Biguanides; Dose-Response Relationship, Drug; Granisetron; Indoles; Male; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Sensory Thresholds; Serotonin Antagonists; Serotonin Receptor Agonists; Spinal Cord; Tropisetron | 1997 |
5-HT3 receptors in the ventromedial nucleus of the hypothalamus and female sexual behavior.
Topics: Animals; Biguanides; Dose-Response Relationship, Drug; Estradiol; Female; Indoles; Ovariectomy; Proestrus; Progesterone; Rats; Rats, Inbred F344; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sex Characteristics; Sexual Behavior, Animal; Time Factors; Tropisetron; Ventromedial Hypothalamic Nucleus | 1997 |
Interactions of ethanol with nicotine, dizocilpine, CGP 40116, and 1-(m-chlorophenyl)-biguanide in rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Behavior, Animal; Biguanides; Central Nervous System Depressants; Dizocilpine Maleate; Drug Interactions; Ethanol; Excitatory Amino Acid Antagonists; Male; Motor Activity; Nicotine; Nicotinic Agonists; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1997 |
5-HT3 receptors induce rises in cytosolic and nuclear calcium in NG108-15 cells via calcium-induced calcium release.
Topics: Biguanides; Calcium; Calcium Channels; Cell Nucleus; Cytosol; Hybrid Cells; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Receptor Agonists; Tumor Cells, Cultured | 1997 |
High calcium permeability of serotonin 5-HT3 receptors on presynaptic nerve terminals from rat striatum.
Topics: Animals; Biguanides; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Membrane Permeability; Corpus Striatum; Glioma; Hybrid Cells; Immunohistochemistry; Indoles; Ion Channel Gating; Mice; Microscopy, Confocal; Neuroblastoma; Nitrendipine; Potassium; Presynaptic Terminals; Rats; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Serotonin Receptor Agonists; Synaptosomes; Tropisetron | 1998 |
c-Fos induction in the rostroventrolateral medulla by 5-HT3 receptor activation in the nucleus tractus solitarius.
Topics: Analysis of Variance; Animals; Biguanides; Male; Medulla Oblongata; Microinjections; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Serotonin Receptor Agonists; Solitary Nucleus | 1998 |
Different efficacy of specific agonists at 5-HT3 receptor splice variants: the role of the extra six amino acid segment.
Topics: Biguanides; Cell Line; Humans; Mutagenesis, Site-Directed; Radioligand Assay; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; RNA Splicing; Serotonin; Serotonin Receptor Agonists | 1998 |
Dorsal medullary 5-HT3 receptors and sympathetic premotor neurones in the rat.
Topics: Action Potentials; Animals; Aorta, Abdominal; Baroreflex; Biguanides; Blood Pressure; Carbon Dioxide; Cardiotonic Agents; Cardiovascular System; Carotid Body; Electrophysiology; Ligation; Lung; Male; Microinjections; Motor Neurons; Phenylephrine; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Respiration; Serotonin Receptor Agonists; Solitary Nucleus; Sympathetic Nervous System | 1998 |
The 5-HT3 receptor agonist attenuates the action of antidepressants in the forced swim test in rats.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Biguanides; Desipramine; Imipramine; Indoles; Male; Mianserin; Motor Activity; Rats; Rats, Wistar; Serotonin Antagonists; Serotonin Receptor Agonists; Swimming; Tropisetron; Volition | 1998 |
Prior repeated exposure to a 5-HT3 receptor agonist does not alter the ethanol-induced conditioned taste aversion in rats.
Topics: Animals; Avoidance Learning; Biguanides; Central Nervous System Depressants; Ethanol; Injections, Intraventricular; Male; Rats; Rats, Wistar; Serotonin Receptor Agonists; Taste | 1998 |
Discrimination of ethanol in rats: effects of nicotine, diazepam, CGP 40116, and 1-(m-chlorophenyl)-biguanide.
Topics: 2-Amino-5-phosphonovalerate; Animals; Biguanides; Diazepam; Discrimination Learning; Drug Interactions; Ethanol; GABA Modulators; Male; Nicotine; Nicotinic Agonists; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Reinforcement Schedule; Serotonin Receptor Agonists | 1998 |
Functional integration among 5-hydroxytryptamine receptor families in the control of female rat sexual behavior.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Biguanides; Drug Combinations; Female; Indoles; Ovariectomy; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sexual Behavior, Animal; Tropisetron | 1998 |
Blockade of accumbens 5-HT3 receptor down-regulation by ondansetron administered during continuous cocaine administration.
Topics: Analysis of Variance; Animals; Biguanides; Brain; Calcium; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Down-Regulation; In Vitro Techniques; Infusion Pumps; Injections, Subcutaneous; Male; Ondansetron; Potassium; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Serotonin Receptor Agonists | 1999 |
Effects of accumbens m-chlorophenylbiguanide microinjections on sleep and waking in intact and 6-hydroxydopamine-treated rats.
Topics: Adrenergic Agents; Animals; Antioxidants; Ascorbic Acid; Biguanides; Injections, Intraventricular; Male; Microinjections; Nucleus Accumbens; Oxidopamine; Rats; Rats, Wistar; Serotonin Antagonists; Serotonin Receptor Agonists; Sleep; Sleep Stages; Sodium Chloride; Tropanes; Wakefulness | 1999 |
Identification of a domain affecting agonist potency of meta-chlorophenylbiguanide in 5-HT3 receptors.
Topics: Amino Acid Sequence; Animals; Biguanides; Binding Sites; Dose-Response Relationship, Drug; Electrophysiology; Gene Expression; Humans; Membrane Potentials; Molecular Sequence Data; Mutation; Oocytes; Patch-Clamp Techniques; Rats; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Serotonin Receptor Agonists; Xenopus | 1999 |
Withdrawal from continuous cocaine administration: time dependent changes in accumbens 5-HT3 receptor function and behavioral tolerance.
Topics: Animals; Behavior, Animal; Biguanides; Cocaine; Dopamine; Drug Tolerance; Male; Nucleus Accumbens; Potassium; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Time Factors | 1999 |
Modulation of afferent-evoked neurotransmission by 5-HT3 receptors in young rat dorsal horn neurones in vitro: a putative mechanism of 5-HT3 induced anti-nociception.
Topics: Analgesia; Animals; Biguanides; In Vitro Techniques; Membrane Potentials; Neurons, Afferent; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Reflex; Serotonin; Spinal Cord; Synaptic Transmission | 1999 |
Effects of various serotonin agonists, antagonists, and uptake inhibitors on the discriminative stimulus effects of methamphetamine in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Biguanides; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Drug Interactions; Indoles; Male; Methamphetamine; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tropisetron | 1999 |
The pharmacological and functional characteristics of the serotonin 5-HT(3A) receptor are specifically modified by a 5-HT(3B) receptor subunit.
Topics: Amygdala; Animals; Base Sequence; Biguanides; Brain; Calcium; Cell Line; Cloning, Molecular; Entorhinal Cortex; Female; Gene Expression Regulation; Humans; Kinetics; Macromolecular Substances; Membrane Potentials; Molecular Sequence Data; Neurons; Oocytes; Open Reading Frames; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Recombinant Proteins; Serotonin; Serotonin Receptor Agonists; Telencephalon; Transcription, Genetic; Transfection; Xenopus laevis | 1999 |
The GABA(B) receptor antagonist CGP36742 improves learned helplessness in rats.
Topics: Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Baclofen; Behavior, Animal; Biguanides; Dose-Response Relationship, Drug; Escape Reaction; GABA Agonists; GABA Antagonists; GABA-B Receptor Antagonists; Helplessness, Learned; Imipramine; Indoles; Male; Organophosphorus Compounds; Rats; Rats, Wistar; Receptors, GABA-B; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Serotonin Receptor Agonists; Tropisetron | 1999 |
The role of tryptophan residues in the 5-Hydroxytryptamine(3) receptor ligand binding domain.
Topics: Amino Acid Sequence; Biguanides; Cell Line; Dose-Response Relationship, Drug; Humans; Immunohistochemistry; Kinetics; Ligands; Molecular Sequence Data; Mutagenesis, Site-Directed; Patch-Clamp Techniques; Protein Binding; Protein Structure, Tertiary; Receptors, Serotonin; Sequence Homology, Amino Acid; Serotonin; Serotonin Antagonists; Structure-Activity Relationship; Tryptophan | 2000 |
Cloning, expression, and characterization of ferret 5-HT(3) receptor subunit.
Topics: Alternative Splicing; Amino Acid Sequence; Animals; Biguanides; Binding, Competitive; Cell Line; Cloning, Molecular; DNA, Complementary; Dose-Response Relationship, Drug; Electrophysiology; Ferrets; Gene Expression; Humans; Imidazoles; Indoles; Kruppel-Like Factor 6; Kruppel-Like Transcription Factors; Membrane Potentials; Molecular Sequence Data; Ondansetron; Piperazines; Proto-Oncogene Proteins; Radioligand Assay; Rats; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; RNA, Messenger; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tissue Distribution; Trans-Activators; Tritium; Tubocurarine | 2000 |
Mesenteric vasoconstrictor response to 5-hydroxytryptamine in the in situ blood autoperfused rat mesentery: involvement of 5-HT(2B) and/or 5-HT(2C) receptor activation.
Topics: Amphetamines; Animals; Biguanides; Dose-Response Relationship, Drug; Enalapril; Indoles; Indomethacin; Male; Mesenteric Arteries; Mesentery; Perfusion; Piperazines; Prazosin; Propranolol; Pyridines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Splanchnic Circulation; Vasoconstriction | 2000 |
Bradycardic responses to microinjection of N-methyl-D-aspartate into the nucleus tractus solitarius are inhibited by local activation of 5-HT(3) receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Baroreflex; Bicuculline; Biguanides; Excitatory Amino Acid Agonists; GABA Antagonists; Granisetron; Heart Rate; Hemodynamics; Male; Microinjections; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Serotonin Receptor Agonists; Solitary Nucleus; Sympathetic Nervous System | 2000 |
Nicotinic receptors co-localize with 5-HT(3) serotonin receptors on striatal nerve terminals.
Topics: Animals; Biguanides; Blotting, Western; Calcium; Electric Stimulation; Immunohistochemistry; In Vitro Techniques; Male; Microscopy, Confocal; Neostriatum; Nerve Endings; Nicotine; Nicotinic Agonists; Precipitin Tests; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Receptor Agonists | 2000 |
Presynaptic 5-HT3 receptor-mediated modulation of synaptic GABA release in the mechanically dissociated rat amygdala neurons.
Topics: Amygdala; Animals; Biguanides; Calcium; Down-Regulation; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Neural Inhibition; Patch-Clamp Techniques; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, Presynaptic; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Receptor Agonists; Synaptic Transmission | 2000 |
Pharmacological profile of YM-31636, a novel 5-HT3 receptor agonist, in vitro.
Topics: Acetylcholine; Action Potentials; Animals; Anthraquinones; Atrial Function; Biguanides; Binding, Competitive; Colon; Dinoprostone; Dose-Response Relationship, Drug; Guinea Pigs; Heart Atria; Humans; In Vitro Techniques; Muscle Contraction; Myocardial Contraction; Pyrroles; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin Receptor Agonists; Thiazoles | 2000 |
Postsynaptic target regulates functional responses induced by 5-HT3 serotonin receptors on axonal varicosities of NG108-15 hybrid neuroblastoma cells.
Topics: Animals; Axons; Biguanides; Calcium; Cell Differentiation; Coculture Techniques; Culture Media, Conditioned; Hybrid Cells; Muscle Fibers, Skeletal; Neuroblastoma; Neurons; Rats; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Receptor Agonists; Synapses; Tumor Cells, Cultured | 2001 |
Serotonin increases the incidence of primary afferent-evoked long-term depression in rat deep dorsal horn neurons.
Topics: Afferent Pathways; Amphetamines; Animals; Animals, Newborn; Biguanides; Boron Compounds; Excitatory Postsynaptic Potentials; Long-Term Potentiation; Methacrylates; Methylmethacrylates; Nerve Tissue Proteins; Neuronal Plasticity; Patch-Clamp Techniques; Posterior Horn Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Receptor Agonists; Single-Blind Method; Synaptic Transmission | 2001 |
The anxiolytic-like effect of MCI-225, a selective NA reuptake inhibitor with 5-HT3 receptor antagonism.
Topics: Adrenergic Uptake Inhibitors; Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Biguanides; Male; Norepinephrine; Ondansetron; Piperazines; Psychotropic Drugs; Pyrimidines; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Serotonin Receptor Agonists | 2001 |
Hypoglossal nerve response to 5-HT3 drugs injected into the XII nucleus and vena cava in the rat.
Topics: Animals; Biguanides; Hypoglossal Nerve; Injections, Intravenous; Male; Microinjections; Motor Neurons; Nodose Ganglion; Ondansetron; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Serotonin Receptor Agonists; Sleep Apnea, Obstructive; Sleep, REM; Venae Cavae | 2001 |
Central 5-HT3 receptor stimulation by m-CPBG increases blood glucose in rats.
Topics: Animals; Biguanides; Blood Glucose; Fasting; Food; Injections, Intraventricular; Kinetics; Male; Ondansetron; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Restraint, Physical; Serotonin Antagonists; Serotonin Receptor Agonists; Stress, Physiological | 2002 |
Glutamate and NO mediation of the pressor response to 5-HT3 receptor stimulation in the nucleus tractus solitarii.
Topics: Animals; Biguanides; Blood Pressure; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; Guanylate Cyclase; Indazoles; Male; Neurons; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Pressoreceptors; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Reflex; Serotonin; Serotonin Receptor Agonists; Solitary Nucleus; Synaptic Transmission | 2002 |
Serotonin(3) receptor stimulation in the nucleus tractus solitarii activates non-catecholaminergic neurons in the rat ventrolateral medulla.
Topics: Animals; Biguanides; Catecholamines; Chloralose; Gene Expression Regulation; Horseradish Peroxidase; Immunohistochemistry; Male; Medulla Oblongata; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Receptor Agonists; Solitary Nucleus; Tyrosine 3-Monooxygenase; Urethane | 2002 |
Pharmacology of serotonin receptors modulating electrically-induced [3h]-norepinephrine release from isolated mammalian iris-ciliary bodies.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Biguanides; Cattle; Ciliary Body; Dose-Response Relationship, Drug; Electric Stimulation; Humans; In Vitro Techniques; Iris; Norepinephrine; Piperidines; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sulfonamides; Tritium; Tropanes | 2002 |
Endogenous cannabinoid, anandamide, acts as a noncompetitive inhibitor on 5-HT3 receptor-mediated responses in Xenopus oocytes.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Analysis of Variance; Animals; Arachidonic Acids; Biguanides; Cannabinoids; Chelating Agents; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Electrophysiology; Endocannabinoids; Enzyme Inhibitors; Female; Indazoles; Membrane Potentials; Oocytes; Pertussis Toxin; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptors, Serotonin, 5-HT3; Rimonabant; RNA, Complementary; Serotonin; Serotonin 5-HT3 Receptor Antagonists; Serotonin Receptor Agonists; Thionucleotides; Tropanes; Xenopus laevis | 2002 |
Central 5-HT(3) receptors and water intake in rats.
Topics: Angiotensins; Animals; Autonomic Pathways; Avoidance Learning; Biguanides; Brain Chemistry; Drinking; Eating; Indazoles; Injections, Intraventricular; Male; Motor Activity; Osmolar Concentration; Parasympathetic Nervous System; Polyethylene Glycols; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Serotonin Receptor Agonists; Tropanes; Water Deprivation | 2002 |
5-HT3 receptors in selective animal models of cognition.
Topics: Animals; Biguanides; Cognition; Ligands; Male; Maze Learning; Mice; Ondansetron; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Scopolamine; Serotonin Antagonists; Signal Transduction | 2002 |
Introduction of the 5-HT3B subunit alters the functional properties of 5-HT3 receptors native to neuroblastoma cells.
Topics: Animals; Biguanides; Calcium; Cell Differentiation; Cell Line; Dose-Response Relationship, Drug; Drug Interactions; Fluorescence; Gene Expression; Green Fluorescent Proteins; Luminescent Proteins; Mice; Molecular Sequence Data; Neuroblastoma; Ondansetron; Patch-Clamp Techniques; Protein Subunits; Rats; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Recombinant Fusion Proteins; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Transfection | 2003 |
Conformationally-restricted analogues and partition coefficients of the 5-HT3 serotonin receptor ligands meta-chlorophenylbiguanide (mCPBG) and meta-chlorophenylguanidine (mCPG).
Topics: Biguanides; Chemical Phenomena; Chemistry, Physical; Guanidine; Ligands; Magnetic Resonance Spectroscopy; Molecular Conformation; Radioligand Assay; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Solubility; Structure-Activity Relationship | 2003 |
Effect of pharmacologically induced smooth muscle activation on permeability in murine colitis.
Topics: Albuterol; Animals; Biguanides; Carbachol; Colitis; Dextran Sulfate; Disease Models, Animal; Female; Intestinal Absorption; Mice; Mice, Inbred BALB C; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Organ Culture Techniques; Permeability; Phenylephrine | 2003 |
Central 5-HT2B/2C and 5-HT3 receptor stimulation decreases salt intake in sodium-depleted rats.
Topics: Animals; Biguanides; Blood Pressure; Diuretics; Dose-Response Relationship, Drug; Drinking; Drug Interactions; Feeding Behavior; Furosemide; Indazoles; Indoles; Injections, Intraventricular; Lithium Chloride; Male; Piperazines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Saccharin; Serotonin Antagonists; Serotonin Receptor Agonists; Sodium; Time Factors; Tropanes | 2003 |
Excitatory action of prostanoids on the ferret isolated vagus nerve preparation.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Biguanides; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Electrophysiology; Epoprostenol; Ferrets; Hydantoins; Iloprost; In Vitro Techniques; Male; Prostaglandins; Prostaglandins F, Synthetic; Serotonin; Vagus Nerve | 2004 |
The 5-HT3 receptor facilitates at-level mechanical allodynia following spinal cord injury.
Topics: 5,6-Dihydroxytryptamine; Animals; Behavior, Animal; Biguanides; Dose-Response Relationship, Drug; Drug Interactions; Escape Reaction; Hyperesthesia; Immunohistochemistry; Male; Methysergide; Neurotoxins; Ondansetron; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Wistar; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spinal Cord Injuries; Time Factors | 2004 |
Acetaminophen: a central analgesic drug that involves a spinal tropisetron-sensitive, non-5-HT(3) receptor-mediated effect.
Topics: Acetaminophen; Analgesics; Animals; Biguanides; Drug Interactions; Indoles; Male; Oligodeoxyribonucleotides, Antisense; Rats; Receptors, Serotonin, 5-HT3; Serotonin 5-HT3 Receptor Antagonists; Serotonin Antagonists; Spinal Cord; Tropisetron | 2004 |
Serotonin type 3 receptors stimulate offensive aggression in Syrian hamsters.
Topics: Age Factors; Aggression; Agonistic Behavior; Animals; Biguanides; Cocaine; Cricetinae; Indoles; Male; Mesocricetus; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Serotonin Receptor Agonists; Signal Transduction; Tropisetron | 2005 |
Role of central 5-HT3 receptors in the control of blood pressure in stressed and non-stressed rats.
Topics: Adaptation, Physiological; Animals; Biguanides; Blood Pressure; Brain; Heart Rate; Injections, Intraventricular; Male; Ondansetron; Rats; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Stress, Psychological | 2004 |
Calcium influx through presynaptic 5-HT3 receptors facilitates GABA release in the hippocampus: in vitro slice and synaptosome studies.
Topics: Animals; Animals, Newborn; Bicuculline; Biguanides; Cadmium; Calcium; Calcium Channel Blockers; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Indoles; Membrane Potentials; Neural Inhibition; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Presynaptic; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin 5-HT3 Receptor Antagonists; Serotonin Receptor Agonists; Sucrose; Synaptosomes; Tritium; Tropisetron | 2004 |
Effects of quipazine and m-chlorophenylbiguanide (m-CPBG) on the discrimination of durations: evidence for the involvement of 5-HT2A but not 5-HT3 receptors.
Topics: Animals; Biguanides; Discrimination Learning; Discrimination, Psychological; Female; Ketanserin; Quipazine; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Serotonin Receptor Agonists; Tropanes | 2005 |
Involvement of spinal serotonin receptors in the regulation of intraspinal acetylcholine release.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholine; Amphetamines; Animals; Biguanides; Citalopram; Dose-Response Relationship, Drug; Ketanserin; Male; Microdialysis; Piperazines; Pyridines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spinal Cord; Time Factors | 2005 |
Effects of quipazine and m-chlorophenylbiguanide (m-CPBG) on temporal differentiation: evidence for the involvement of 5-HT2A but not 5-HT3 receptors in interval timing behaviour.
Topics: Animals; Biguanides; Conditioning, Operant; Dose-Response Relationship, Drug; Female; Injections, Intraperitoneal; Injections, Subcutaneous; Ketanserin; Psychometrics; Quipazine; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin, 5-HT3; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin 5-HT3 Receptor Agonists; Serotonin 5-HT3 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists; Task Performance and Analysis; Time Perception; Tropanes | 2005 |
The loop C region of the murine 5-HT3A receptor contributes to the differential actions of 5-hydroxytryptamine and m-chlorophenylbiguanide.
Topics: Amino Acid Sequence; Animals; Biguanides; Cell Line; Electrophysiology; Humans; Methylation; Mice; Models, Molecular; Mutation; Oocytes; Patch-Clamp Techniques; Protein Structure, Tertiary; Radioligand Assay; Receptors, Serotonin, 5-HT3; Sequence Alignment; Serotonin; Serotonin 5-HT3 Receptor Agonists; Serotonin Receptor Agonists; Xenopus laevis | 2005 |
The serotonin type 3A receptor facilitates luteinizing hormone release and LHbeta promoter activity in immortalized pituitary gonadotropes.
Topics: Animals; Biguanides; Blotting, Northern; Cell Line; Luciferases; Luteinizing Hormone; Luteinizing Hormone, beta Subunit; Pituitary Gland; Promoter Regions, Genetic; Radioimmunoassay; Rats; Receptors, Serotonin, 5-HT3; Reverse Transcriptase Polymerase Chain Reaction; Serotonin Antagonists; Serotonin Receptor Agonists; Tropanes | 2005 |
Molecular cloning and pharmacological characterization of serotonin 5-HT(3A) receptor subtype in dog.
Topics: Amino Acid Sequence; Animals; Biguanides; Cloning, Molecular; DNA, Complementary; Dogs; Dose-Response Relationship, Drug; Female; Membrane Potentials; Molecular Sequence Data; Mutation; Ondansetron; Oocytes; Receptors, Serotonin, 5-HT3; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Xenopus | 2006 |
Role of 5-HT3 and 5-HT2C receptors located within the medial amygdala in the control of salt intake in sodium-depleted rats.
Topics: Amygdala; Analysis of Variance; Animals; Avoidance Learning; Behavior, Animal; Biguanides; Dose-Response Relationship, Drug; Drinking; Drug Interactions; Feeding Behavior; Furosemide; Male; Ondansetron; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin, 5-HT3; Renal Insufficiency; Saccharin; Serotonin Antagonists; Serotonin Receptor Agonists; Sodium; Time Factors | 2006 |
Effects of repeated daily treatments with a 5-HT3 receptor antagonist on dopamine neurotransmission and functional activity of 5-HT3 receptors within the nucleus accumbens of Wistar rats.
Topics: Animals; Biguanides; Dopamine; Male; Microdialysis; Nucleus Accumbens; Rats; Rats, Wistar; Receptors, Serotonin, 5-HT3; Serotonin 5-HT3 Receptor Agonists; Serotonin 5-HT3 Receptor Antagonists; Serotonin Antagonists; Synaptic Transmission; Tropanes; Ventral Tegmental Area | 2006 |
Lack of reciprocity between opioid and 5-HT3 receptors for antinociception in rat spinal cord.
Topics: Analgesia; Analgesics, Opioid; Animals; Biguanides; Dose-Response Relationship, Drug; Formaldehyde; Hindlimb; Indazoles; Injections, Spinal; Male; Morphine; Motor Activity; Muscle Tonus; Naloxone; Narcotic Antagonists; Ondansetron; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Receptors, Serotonin, 5-HT3; Serotonin 5-HT3 Receptor Antagonists; Serotonin Receptor Agonists; Spinal Cord; Tropanes | 2006 |
Activity-dependent modulation of axonal excitability in unmyelinated peripheral rat nerve fibers by the 5-HT(3) serotonin receptor.
Topics: Animals; Axons; Biguanides; Electrophysiology; In Vitro Techniques; Membrane Potentials; Nerve Fibers, Unmyelinated; Neural Conduction; Peripheral Nervous System; Rats; Rats, Wistar; Receptors, Serotonin, 5-HT3; Serotonin | 2006 |
The reinforcing actions of a serotonin-3 receptor agonist within the ventral tegmental area: evidence for subregional and genetic differences and involvement of dopamine neurons.
Topics: Alcohol Drinking; Animals; Biguanides; Cerebrospinal Fluid; Conditioning, Classical; Dopamine; Dopamine Agonists; Female; Indoles; Infusions, Parenteral; Neurons; Quinpirole; Rats; Rats, Wistar; Reinforcement, Psychology; Self Administration; Serotonin 5-HT3 Receptor Agonists; Serotonin Antagonists; Serotonin Receptor Agonists; Tropisetron; Ventral Tegmental Area | 2007 |
Activation of serotonin-3 receptors increases dopamine release within the ventral tegmental area of Wistar and alcohol-preferring (P) rats.
Topics: Animals; Biguanides; Central Nervous System Depressants; Dopamine; Dose-Response Relationship, Drug; Ethanol; Female; Male; Microdialysis; Rats; Rats, Wistar; Receptors, Serotonin, 5-HT3; Serotonin 5-HT3 Receptor Agonists; Serotonin Receptor Agonists; Time Factors; Ventral Tegmental Area | 2006 |
Activation of the serotonin 5-HT3 receptor in the dorsal raphe nucleus suppresses REM sleep in the rat.
Topics: Animals; Biguanides; Depression, Chemical; Electroencephalography; Injections, Intraventricular; Male; Ondansetron; Raphe Nuclei; Rats; Rats, Wistar; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Serotonin Receptor Agonists; Sleep Stages; Sleep, REM | 2008 |
Activation of serotonin 3 receptors changes in vivo auditory responses in the mouse inferior colliculus.
Topics: Acoustic Stimulation; Action Potentials; Animals; Biguanides; Bridged Bicyclo Compounds, Heterocyclic; Electrophysiology; Inferior Colliculi; Male; Mice; Mice, Inbred CBA; Neurons; Ondansetron; Oxazines; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin 5-HT3 Receptor Agonists; Serotonin 5-HT3 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists | 2009 |
Facilitatory actions of serotonin type 3 receptors on GABAergic inhibitory synaptic transmission in the spinal superficial dorsal horn.
Topics: Analysis of Variance; Animals; Biguanides; gamma-Aminobutyric Acid; Gene Expression Regulation; Glutamate Decarboxylase; Green Fluorescent Proteins; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Male; Mice; Mice, Transgenic; Models, Biological; Neural Inhibition; Ondansetron; Patch-Clamp Techniques; Posterior Horn Cells; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin 5-HT3 Receptor Agonists; Serotonin Antagonists; Serotonin Receptor Agonists; Spinal Cord; Synaptic Transmission | 2009 |
Interactions between the anxiogenic effects of CB1 gene disruption and 5-HT3 neurotransmission.
Topics: Animals; Anxiety; Behavior, Animal; Biguanides; Cannabinoid Receptor Modulators; gamma-Aminobutyric Acid; Male; Maze Learning; Mice; Mice, Knockout; Receptor, Cannabinoid, CB1; Receptors, Serotonin, 5-HT3; Serotonin 5-HT3 Receptor Agonists; Species Specificity; Synaptic Transmission | 2009 |
Cross-regulation between colocalized nicotinic acetylcholine and 5-HT3 serotonin receptors on presynaptic nerve terminals.
Topics: Animals; Biguanides; Calcium; Corpus Striatum; Male; Microscopy, Confocal; Nicotine; Nicotinic Agonists; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Receptors, Serotonin, 5-HT3; Serotonin Receptor Agonists; Signal Transduction | 2009 |
Central 5-HT3 receptor-induced hypothermia in mice: interstrain differences and comparison with hypothermia mediated via 5-HT1A receptor.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Biguanides; Blood-Brain Barrier; Body Temperature; Dose-Response Relationship, Drug; Hypothermia; Male; Mice; Mice, Inbred Strains; Ondansetron; Piperazines; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin, 5-HT3; Serotonin 5-HT1 Receptor Antagonists; Serotonin 5-HT3 Receptor Agonists; Serotonin Antagonists; Serotonin Receptor Agonists; Species Specificity | 2009 |
Activation of 5-HT3 receptors leads to altered responses 6 months after MDMA treatment.
Topics: Animals; Biguanides; Brain; Circadian Rhythm; Electroencephalography; Hippocampus; Male; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Polysomnography; Random Allocation; Rats; Receptors, Serotonin, 5-HT3; Serotonin 5-HT3 Receptor Agonists; Serotonin Agents; Serotonin Receptor Agonists; Sleep; Sleep Stages; Theta Rhythm; Time Factors; Wakefulness | 2010 |
Granisetron ameliorates acetic acid-induced colitis in rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Biguanides; Colitis; Colon; Dexamethasone; Disease Models, Animal; Gastrointestinal Agents; Granisetron; Inflammation Mediators; Injections, Intraperitoneal; Interleukin-1beta; Interleukin-6; Male; Malondialdehyde; Peroxidase; Rats; Rats, Sprague-Dawley; Receptors, Serotonin, 5-HT3; Serotonin 5-HT3 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists; Tumor Necrosis Factor-alpha | 2010 |
5-HT3 receptor-dependent modulation of respiratory burst frequency, regularity, and episodicity in isolated adult turtle brainstems.
Topics: Action Potentials; Afferent Pathways; Animals; Biguanides; Dose-Response Relationship, Drug; Hypoglossal Nerve; In Vitro Techniques; Indoles; Physical Stimulation; Receptors, Serotonin, 5-HT3; Respiration; Respiratory Center; Serotonin 5-HT3 Receptor Agonists; Serotonin 5-HT3 Receptor Antagonists; Serotonin Agents; Time Factors; Tropanes; Tropisetron; Turtles | 2010 |
Tropisetron ameliorates ischemic brain injury in an embolic model of stroke.
Topics: Analysis of Variance; Animals; Biguanides; Blood Gas Analysis; Brain Edema; Brain Infarction; Brain Injuries; Cerebral Cortex; Disease Models, Animal; Dose-Response Relationship, Drug; Immunosuppressive Agents; Indoles; Ischemia; Male; Nervous System Diseases; Peroxidase; Rats; Rats, Wistar; Seizures; Serotonin Antagonists; Stroke; Tacrolimus; Tropisetron; Tumor Necrosis Factor-alpha | 2011 |
Blockade of the NMDA and AMPA/kainate receptors in the dorsal raphe nucleus prevents the 5-HT₃ receptor agonist m-chlorophenylbiguanide-induced suppression of REM sleep in the rat.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biguanides; Dose-Response Relationship, Drug; Electroencephalography; Electromyography; Excitatory Amino Acid Antagonists; Male; N-Methylaspartate; Raphe Nuclei; Rats; Rats, Wistar; Receptors, Kainic Acid; Receptors, Serotonin, 5-HT3; Serotonin 5-HT3 Receptor Agonists; Sleep; Sleep Deprivation; Sleep, REM | 2011 |
Multiple opioid receptors mediate the hypotensive response induced by central 5-HT(3) receptor stimulation.
Topics: Animals; Biguanides; Blood Pressure; Heart Rate; Hypotension; Male; Naloxone; Naltrexone; Narcotic Antagonists; Ondansetron; Rats; Rats, Wistar; Receptors, Opioid; Receptors, Serotonin, 5-HT3; Serotonin 5-HT3 Receptor Agonists; Serotonin 5-HT3 Receptor Antagonists | 2011 |
The role of 5-HT(3) receptors in the additive anticonvulsant effects of citalopram and morphine on pentylenetetrazole-induced clonic seizures in mice.
Topics: Analysis of Variance; Animals; Anticonvulsants; Biguanides; Citalopram; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Indoles; Male; Mice; Morphinans; Pentylenetetrazole; Receptors, Serotonin, 5-HT3; Seizures; Serotonin Antagonists; Serotonin Receptor Agonists; Tropisetron | 2011 |
Attenuation of 1-(m-chlorophenyl)-biguanide induced hippocampus-dependent memory impairment by a standardised extract of Bacopa monniera (BESEB CDRI-08).
Topics: Acetylcholine; Animals; Avoidance Learning; Bacopa; Biguanides; Female; Hippocampus; Male; Medicine, Ayurvedic; Memory; Memory Disorders; Plant Extracts; Rats; Rats, Wistar; Receptors, Serotonin, 5-HT3; Serotonin | 2011 |
Central 5-HT3 receptor-induced hypothermia is associated with reduced metabolic rate and increased heat loss.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Biguanides; Body Temperature Regulation; Brain; Carbon Dioxide; Energy Metabolism; Hypothermia; Lipid Metabolism; Male; Mice; Mice, Inbred CBA; Oxygen Consumption; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin, 5-HT3; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT3 Receptor Agonists | 2011 |
Serotonin-mediated modulation of Na+/K+ pump current in rat hippocampal CA1 pyramidal neurons.
Topics: Animals; Animals, Newborn; Biguanides; Biophysics; CA1 Region, Hippocampal; Dose-Response Relationship, Drug; Electric Stimulation; In Vitro Techniques; Neural Inhibition; Patch-Clamp Techniques; Piperazines; Pyramidal Cells; Pyridines; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sodium Channel Blockers; Sodium-Potassium-Exchanging ATPase; Strophanthidin; Tetrodotoxin | 2012 |
Inhibitory effect of ramosetron on corticotropin releasing factor- and soybean oil-induced delays in gastric emptying in rats.
Topics: Animals; Antidiarrheals; Benzamides; Benzimidazoles; Benzyl Compounds; Biguanides; Corticotropin-Releasing Hormone; Dyspepsia; Fenclonine; Gastric Emptying; Irritable Bowel Syndrome; Male; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Soybean Oil | 2012 |
5-HT(3) receptor mediates the dose-dependent effects of citalopram on pentylenetetrazole-induced clonic seizure in mice: involvement of nitric oxide.
Topics: Animals; Anticonvulsants; Biguanides; Citalopram; Dose-Response Relationship, Drug; Enzyme Inhibitors; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pentylenetetrazole; Receptors, Serotonin, 5-HT3; Seizures; Serotonin Receptor Agonists | 2012 |
Effect of chronic activation of 5-HT3 receptors on 5-HT3, 5-HT(1A) and 5-HT(2A) receptors functional activity and expression of key genes of the brain serotonin system.
Topics: Animals; Biguanides; Brain; Mice; Mice, Inbred Strains; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin, 5-HT3; Serotonin 5-HT3 Receptor Agonists | 2012 |
Double dissociation between regulation of conditioned disgust and taste avoidance by serotonin availability at the 5-HT(3) receptor in the posterior and anterior insular cortex.
Topics: 5,6-Dihydroxytryptamine; Animals; Avoidance Learning; Biguanides; Cerebral Cortex; Conditioning, Classical; Emotions; Lithium Chloride; Male; Nausea; Ondansetron; Rats; Rats, Sprague-Dawley; Receptors, Serotonin, 5-HT3; Saccharin; Serotonin 5-HT3 Receptor Agonists; Serotonin 5-HT3 Receptor Antagonists; Taste | 2012 |
A coupled array of noncovalent interactions impacts the function of the 5-HT3A serotonin receptor in an agonist-specific way.
Topics: Amino Acid Sequence; Animals; Biguanides; Binding Sites; Female; Hydrogen Bonding; Mice; Molecular Sequence Data; Mutation; Protein Array Analysis; Protein Binding; Receptors, Serotonin, 5-HT3; Serotonin Receptor Agonists; Xenopus | 2012 |
Tropisetron diminishes demyelination and disease severity in an animal model of multiple sclerosis.
Topics: Animals; Biguanides; Cell Proliferation; Demyelinating Diseases; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Encephalomyelitis, Autoimmune, Experimental; Granisetron; Indoles; Leukocytes, Mononuclear; Mice; Mice, Inbred C57BL; Multiple Sclerosis; Receptors, Serotonin, 5-HT3; Serotonin 5-HT3 Receptor Agonists; Serotonin 5-HT3 Receptor Antagonists; Spinal Cord; Spleen; Treatment Outcome; Tropisetron | 2013 |
Importance of recognition loops B and D in the activation of human 5-HT₃ receptors by 5-HT and meta-chlorophenylbiguanide.
Topics: Animals; Biguanides; DNA Mutational Analysis; Humans; Membrane Potentials; Oocytes; Protein Subunits; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin 5-HT3 Receptor Agonists; Xenopus | 2013 |
Inhibitory effect of the selective serotonin 5-HT₃ receptor antagonist ramosetron on duodenal acidification-induced gastric hypersensitivity in rats.
Topics: Animals; Benzimidazoles; Biguanides; Duodenum; Hydrogen-Ion Concentration; Irritable Bowel Syndrome; Male; Nociception; Quinolizines; Rats; Rats, Sprague-Dawley; Serotonin 5-HT3 Receptor Antagonists; Stomach | 2014 |
Using drug combinations to assess potential contributions of non-GABAA receptors in the discriminative stimulus effects of the neuroactive steroid pregnanolone in rats.
Topics: Animals; Biguanides; Central Nervous System Depressants; Discrimination, Psychological; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; GABA Modulators; Male; Midazolam; Morphine; Narcotics; Phencyclidine; Pregnanolone; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin, 5-HT3; Serotonin 5-HT3 Receptor Agonists | 2014 |
Allosteric activation of the 5-HT3AB receptor by mCPBG.
Topics: Biguanides; Binding Sites; Dose-Response Relationship, Drug; Humans; Protein Subunits; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin 5-HT3 Receptor Agonists; Serotonin Receptor Agonists | 2015 |
Involvement of the serotonergic system of the ventral hippocampus (CA3) on amnesia induced by ACPA in mice.
Topics: Amnesia; Aniline Compounds; Animals; Arachidonic Acids; Biguanides; Bridged Bicyclo Compounds, Heterocyclic; CA3 Region, Hippocampal; Cannabinoid Receptor Agonists; Catheters, Indwelling; Male; Mice; Oxazines; para-Aminobenzoates; Piperidines; Receptor, Cannabinoid, CB1; Receptors, Serotonin, 5-HT3; Receptors, Serotonin, 5-HT4; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 2015 |
Agonist- and antagonist-induced up-regulation of surface 5-HT3 A receptors.
Topics: Animals; Biguanides; Cell Line, Tumor; HEK293 Cells; Humans; Mice; Morphine; Rats; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tropanes; Up-Regulation | 2015 |
A novel 5HT3 antagonist 4i (N-(3-chloro-2-methylphenyl)quinoxalin-2-carboxamide) prevents diabetes-induced depressive phenotypes in mice: Modulation of serotonergic system.
Topics: Animals; Antidepressive Agents; Biguanides; Brain; Depressive Disorder; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Fluoxetine; Male; Mice; Quinoxalines; Random Allocation; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin 5-HT3 Receptor Agonists; Serotonin 5-HT3 Receptor Antagonists | 2016 |
Synergistic effect between prelimbic 5-HT3 and CB1 receptors on memory consolidation deficit in adult male Sprague-Dawley rats: An isobologram analysis.
Topics: Animals; Arachidonic Acids; Avoidance Learning; Biguanides; Bridged Bicyclo Compounds, Heterocyclic; Cannabinoid Receptor Agonists; Cerebral Cortex; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Male; Memory Disorders; Motor Activity; Oxazines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptor, Cannabinoid, CB1; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Serotonin Receptor Agonists | 2016 |
Chronic 5-HT
Topics: Animals; Anticonvulsants; Biguanides; Cerebral Cortex; Dose-Response Relationship, Drug; Hippocampus; Kindling, Neurologic; Male; Memory; Memory Disorders; Mice; Nootropic Agents; Ondansetron; Pentylenetetrazole; Random Allocation; Receptors, Serotonin, 5-HT3; Seizures; Serotonin 5-HT3 Receptor Antagonists; Serotonin Receptor Agonists | 2016 |
Subtle Differences among 5-HT
Topics: Animals; Biguanides; Oocytes; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin 5-HT3 Receptor Agonists; Thymol; Tryptamines; Varenicline; Xenopus laevis | 2017 |
Genistein modulation of seizure: involvement of estrogen and serotonin receptors.
Topics: Animals; Anticonvulsants; Biguanides; Dose-Response Relationship, Drug; Fabaceae; Female; Genistein; Mice; Pentylenetetrazole; Phytoestrogens; Plant Extracts; Receptors, Estrogen; Receptors, Serotonin; Seizures; Serotonin Receptor Agonists | 2017 |
Inhibitory circuit gating of auditory critical-period plasticity.
Topics: Animals; Auditory Cortex; Bicuculline; Biguanides; Evoked Potentials, Auditory, Brain Stem; Excitatory Postsynaptic Potentials; Female; Interneurons; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neuronal Plasticity; Nicotine; Nicotinic Agonists; Otoacoustic Emissions, Spontaneous; Parvalbumins; Sensory Gating; Serotonin Receptor Agonists; Vasoactive Intestinal Peptide | 2018 |
The interplay between 5-HT
Topics: Animals; Anxiety; Behavior, Animal; Biguanides; Male; Mice; Ondansetron; Periaqueductal Gray; Piperazines; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin, 5-HT3; Serotonin | 2022 |