1-(3-c-ethynylribopentofuranosyl)uracil has been researched along with uridine in 10 studies
| Studies (1-(3-c-ethynylribopentofuranosyl)uracil) | Trials (1-(3-c-ethynylribopentofuranosyl)uracil) | Recent Studies (post-2010) (1-(3-c-ethynylribopentofuranosyl)uracil) | Studies (uridine) | Trials (uridine) | Recent Studies (post-2010) (uridine) |
|---|---|---|---|---|---|
| 11 | 0 | 2 | 12,749 | 69 | 1,083 |
| Protein | Taxonomy | 1-(3-c-ethynylribopentofuranosyl)uracil (IC50) | uridine (IC50) |
|---|---|---|---|
| Sodium/nucleoside cotransporter 1 | Homo sapiens (human) | 5.8 | |
| Solute carrier family 28 member 3 | Homo sapiens (human) | 5.4 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (50.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fukushima, M; Hattori, H; Matsuda, A; Sasaki, T; Tanaka, M | 1 |
| Eshima, K; Fukushima, M; Matsuda, A; Sasaki, T; Tabata, S; Tanaka, M | 1 |
| Endo, Y; Matsuda, A; Obata, T; Sasaki, T; Tabata, S; Tanaka, M | 1 |
| Fukushima, M; Kanda, H; Matsuda, A; Sasaki, T; Takatori, S; Tanaka, M; Wataya, Y | 1 |
| Fukushima, M; Kanda, H; Matsuda, A; Sasaki, T; Shimamoto, Y; Takatori, S; Takenaka, K; Tanaka, M; Wataya, Y | 1 |
| Endo, Y; Kadohira, M; Matsuda, A; Murata, D; Obata, T; Sakamoto, K; Sasaki, T; Syouji, Y | 1 |
| Hrdlicka, PJ; Jepsen, JS; Nielsen, C; Wengel, J | 1 |
| Fukushima, M; Kanda, H; Kim, HS; Matsuda, A; Naito, T; Sasaki, T; Takatori, S; Takenaka, K; Wataya, Y; Yokogawa, T | 1 |
| Abe, K; Ishigami, T; Ohno, S; Shyu, AB; Umemura, S; Yamashita, A | 1 |
| Aoki, H; Echizenya, S; Fujii, Y; Ichikawa, S; Isogawa, M; Kondo, T; Maenaka, K; Matsuda, A; Natsumeda, M; Ogura, R; Ohtsu, N; Otsuguro, S; Sakaitani, M; Tsukamoto, Y | 1 |
1 review(s) available for 1-(3-c-ethynylribopentofuranosyl)uracil and uridine
| Article | Year |
|---|---|
[Antitumor effect and mechanism of a novel multifunctional nucleoside, 3'-ethynylnucleoside, on human cancers].
Topics: Animals; Antineoplastic Agents; Cell Division; Cytidine; DNA, Neoplasm; Humans; Mice; Mice, Nude; RNA, Neoplasm; Stomach Neoplasms; Tumor Cells, Cultured; Uridine | 1997 |
9 other study(ies) available for 1-(3-c-ethynylribopentofuranosyl)uracil and uridine
| Article | Year |
|---|---|
Nucleosides and nucleotides. 158. 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)-cytosine, 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)uracil, and their nucleobase analogues as new potential multifunctional antitumor nucleosides with a broad spectrum of activit
Topics: Animals; Antineoplastic Agents; Cytidine; Humans; Magnetic Resonance Spectroscopy; Mice; Spectrometry, Mass, Fast Atom Bombardment; Uracil; Uridine | 1996 |
Anti-tumor mechanisms of 3'-ethynyluridine and 3'-ethynylcytidine as RNA synthesis inhibitors: development and characterization of 3'-ethynyluridine-resistant cells.
Topics: Antimetabolites, Antineoplastic; Cytidine; DNA; Drug Resistance; Humans; Nucleic Acid Synthesis Inhibitors; RNA; Tumor Cells, Cultured; Uridine | 1997 |
Cytotoxic mechanisms of new antitumor nucleoside analogues, 3'-ethynylcytidine (ECyd) and 3'-ethynyluridine (EUrd).
Topics: Animals; Antimetabolites, Antineoplastic; Biotransformation; Cell Death; Cell Line; Cytidine; Female; Fibrosarcoma; Humans; Mammary Neoplasms, Experimental; Mice; Models, Chemical; Tumor Cells, Cultured; Uridine | 1997 |
Antitumor mechanisms and metabolism of the novel antitumor nucleoside analogues, 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)cytosine and 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)uracil.
Topics: Animals; Antineoplastic Agents; Cytidine; Female; Humans; Mice; Phosphorylation; Rats; RNA; Tumor Cells, Cultured; Uridine | 1999 |
A crucial role of uridine/cytidine kinase 2 in antitumor activity of 3'-ethynyl nucleosides.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cytidine; Dose-Response Relationship, Drug; Humans; Point Mutation; Uridine; Uridine Kinase | 2004 |
Synthesis and biological evaluation of nucleobase-modified analogs of the anticancer compounds 3'-C-ethynyluridine (EUrd) and 3'-C-ethynylcytidine (ECyd).
Topics: Antineoplastic Agents; Cell Line, Tumor; Cytidine; Drug Screening Assays, Antitumor; Humans; Magnetic Resonance Spectroscopy; Uridine | 2005 |
Inhibitory mechanisms of 1-(3-C-ethynyl-beta-D-ribopentofuranosyl)uracil (EUrd) on RNA synthesis.
Topics: Animals; Cell Line, Tumor; Female; Kinetics; Mice; Nucleic Acid Synthesis Inhibitors; RNA; Uridine | 2005 |
Analysis of interferon-beta mRNA stability control after poly(I:C) stimulation using RNA metabolic labeling by ethynyluridine.
Topics: Cell Line; Humans; Interferon-beta; Poly I-C; RNA Stability; RNA, Messenger; Transcription, Genetic; Uridine | 2012 |
Chemical Screening Identifies EUrd as a Novel Inhibitor Against Temozolomide-Resistant Glioblastoma-Initiating Cells.
Topics: 5'-Nucleotidase; Animals; Brain Neoplasms; Carcinogenesis; Cell Cycle Checkpoints; Cell Death; Cell Line, Tumor; Dacarbazine; Drug Evaluation, Preclinical; Drug Resistance, Neoplasm; Glioblastoma; Glycoproteins; Humans; Mice, SCID; Temozolomide; Uracil; Uridine | 2016 |