1-(2-trifluoromethylphenyl)imidazole and 7-nitroindazole

1-(2-trifluoromethylphenyl)imidazole has been researched along with 7-nitroindazole in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (33.33)18.2507
2000's5 (41.67)29.6817
2010's3 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Boulouard, M; Collot, V; Dauphin, F; Duval, D; Gsell, W; Hommet, Y; MacKenzie, ET; Rault, S; Schumann, P; Sopkova, J1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Andrews, JS; Annedi, SC; Bunton, D; Christie, L; Lee, DK; Maddaford, SP; Mladenova, G; Porreca, F; Rakhit, S; Ramnauth, J; Zhang, D1
Bath, PM; Beech, JS; Escott, KJ; Haga, KK; Meldrum, BS; Williams, SC1
Handy, RL; Moore, PK1
Chemtob, S; Dumont, I; Hardy, P; Hou, X; Nuyt, AM; Peri, KG; Varma, DR1
Heinemann, A; Holzer, P1
Hölscher, C1
Bourin, M; Vasar, E; Volke, V; Wegener, G1
Kikuchi-Utsumi, K; Matsumura, N; Nakaki, T1
Krass, M; Rünkorg, K; Volke, V; Wegener, G1
Belzung, C; Mutlu, O; Ulak, G1

Other Studies

12 other study(ies) available for 1-(2-trifluoromethylphenyl)imidazole and 7-nitroindazole

ArticleYear
Inhibition of neuronal nitric oxide synthase by 7-methoxyindazole and related substituted indazoles.
    Bioorganic & medicinal chemistry letters, 2001, May-07, Volume: 11, Issue:9

    Topics: Analgesics; Animals; Arginine; Cerebellum; Dose-Response Relationship, Drug; Electrons; Enzyme Inhibitors; Indazoles; Mice; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Pain Measurement; Rats; Structure-Activity Relationship

2001
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Discovery of N-(3-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indol-6-yl) thiophene-2-carboximidamide as a selective inhibitor of human neuronal nitric oxide synthase (nNOS) for the treatment of pain.
    Journal of medicinal chemistry, 2011, Oct-27, Volume: 54, Issue:20

    Topics: Analgesics; Coronary Vessels; Cytochrome P-450 Enzyme Inhibitors; Hot Temperature; Humans; Hyperalgesia; Indoles; Ligation; Neuralgia; Nitric Oxide Synthase Type I; Pain; Pyridines; Spinal Nerves; Stereoisomerism; Structure-Activity Relationship; Thiophenes; Vascular Resistance; Vasoconstriction

2011
Cerebroprotective effect of the nitric oxide synthase inhibitors, 1-(2-trifluoromethylphenyl) imidazole and 7-nitro indazole, after transient focal cerebral ischemia in the rat.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1998, Volume: 18, Issue:3

    Topics: Animals; Cell Survival; Enzyme Inhibitors; Imidazoles; Indazoles; Ischemic Attack, Transient; Male; Neurons; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley

1998
Effects of selective inhibitors of neuronal nitric oxide synthase on carrageenan-induced mechanical and thermal hyperalgesia.
    Neuropharmacology, 1998, Volume: 37, Issue:1

    Topics: Animals; Carrageenan; Enzyme Inhibitors; Imidazoles; Indazoles; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Pain Threshold; Rats; Rats, Wistar

1998
Developmentally increased cerebrovascular NO in newborn pigs curtails cerebral blood flow autoregulation.
    Pediatric research, 1999, Volume: 46, Issue:4

    Topics: Animals; Animals, Newborn; Blood Pressure; Brain; Cerebrovascular Circulation; Enzyme Inhibitors; Homeostasis; Imidazoles; Indazoles; Microcirculation; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Swine

1999
Intestinal motor depression by 7-nitroindazole through an action unrelated to nitric oxide synthase inhibition.
    Pharmacology, 1999, Volume: 59, Issue:6

    Topics: Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Gastrointestinal Motility; Guinea Pigs; Imidazoles; In Vitro Techniques; Indazoles; Indomethacin; Intestine, Small; Male; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peptide Fragments; Peristalsis; Sincalide; Substance P; Tetrodotoxin

1999
Different strains of rats show different sensitivity to block of long-term potentiation by nitric oxide synthase inhibitors.
    European journal of pharmacology, 2002, Dec-20, Volume: 457, Issue:2-3

    Topics: Animals; Brain; Electric Stimulation; Enzyme Inhibitors; Imidazoles; Indazoles; Long-Term Potentiation; Male; Nitric Oxide Synthase; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Rats, Wistar; Species Specificity

2002
Antidepressant- and anxiolytic-like effects of selective neuronal NOS inhibitor 1-(2-trifluoromethylphenyl)-imidazole in mice.
    Behavioural brain research, 2003, Mar-18, Volume: 140, Issue:1-2

    Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Anxiety; Arginine; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Exploratory Behavior; Imidazoles; Imipramine; Immobilization; Indazoles; Male; Mice; Mice, Inbred C57BL; Motor Activity; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Reaction Time; Swimming

2003
Activities of 7-nitroindazole and 1-(2-(trifluoromethylphenyl)-imidazole independent of neuronal nitric-oxide synthase inhibition.
    The Journal of pharmacology and experimental therapeutics, 2008, Volume: 325, Issue:2

    Topics: Aminobutyrates; Animals; Anticonvulsants; Brain; Herbicides; Imidazoles; Indazoles; Male; Mice; Mice, Inbred Strains; Mice, Mutant Strains; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type I; Seizures

2008
Nitric oxide is involved in the regulation of marble-burying behavior.
    Neuroscience letters, 2010, Aug-09, Volume: 480, Issue:1

    Topics: Agmatine; Animals; Arginine; Behavior, Animal; Citalopram; Imidazoles; Indazoles; Male; Mice; Mice, Inbred C57BL; Nitric Oxide; Nitric Oxide Synthase Type I; Obsessive-Compulsive Disorder; Paroxetine; Selective Serotonin Reuptake Inhibitors

2010
Effects of nitric oxide synthase inhibitors 1-(2-trifluoromethylphenyl)--imidazole (TRIM) and 7-nitroindazole (7-NI) on learning and memory in mice.
    Fundamental & clinical pharmacology, 2011, Volume: 25, Issue:3

    Topics: Animals; Enzyme Inhibitors; Food Preferences; Hippocampus; Imidazoles; Indazoles; Learning; Locomotion; Long-Term Potentiation; Male; Maze Learning; Memory; Mice; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III

2011