1-(2-nitro-1-imidazolyl)-3-aziridino-2-propanol has been researched along with tirapazamine in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.14) | 18.7374 |
| 1990's | 13 (92.86) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Stratford, IJ | 1 |
| Chaplin, DJ | 1 |
| Durand, RE; Olive, PL | 1 |
| Adams, GE; Bremner, JC; Cole, S; Edwards, HS; Stratford, IJ | 1 |
| Hall, EJ; He, ZY; Hei, TK; Piao, CQ | 1 |
| Bridges, JM; Lappin, TR; MacManus, MP; McAleer, JJ; McKeown, SR | 1 |
| Adams, GE; Bowler, J; Bremner, JC; Stratford, IJ | 1 |
| Adams, GE; Godden, J; Keohane, A; Stratford, IJ | 1 |
| Kennedy, KA | 1 |
| Olive, PL | 1 |
| Koch, CJ | 1 |
| Stratford, IJ; Workman, P | 1 |
| Chinje, EC; Harris, AL; Patterson, AV; Saunders, MP; Strafford, IJ; Talbot, DC | 1 |
| Melo, T; Misra, V; Rauth, AM | 1 |
3 review(s) available for 1-(2-nitro-1-imidazolyl)-3-aziridino-2-propanol and tirapazamine
| Article | Year |
|---|---|
Bioreductive drugs in cancer therapy.
Topics: Animals; Antineoplastic Agents; Antioxidants; Cell Hypoxia; Humans; Misonidazole; Neoplasms; Nitroimidazoles; Prodrugs; Radiation-Sensitizing Agents; Tirapazamine; Triazines | 1992 |
Hypoxic cells as specific drug targets for chemotherapy.
Topics: Animals; Antineoplastic Agents; DNA Damage; DNA Repair; Humans; Misonidazole; Mitomycin; Mitomycins; Oxygen; Tirapazamine; Triazines | 1987 |
The experimental development of bioreductive drugs and their role in cancer therapy.
Topics: Animals; Antineoplastic Agents; Aziridines; Combined Modality Therapy; DNA Damage; Humans; Indolequinones; Indoles; Misonidazole; Neoplasms; Radiation-Sensitizing Agents; Tirapazamine; Triazines | 1993 |
11 other study(ies) available for 1-(2-nitro-1-imidazolyl)-3-aziridino-2-propanol and tirapazamine
| Article | Year |
|---|---|
Bioreductive therapy.
Topics: Antineoplastic Agents; Cell Hypoxia; Humans; Misonidazole; Nitroimidazoles; Oxidation-Reduction; Prodrugs; Radiation-Sensitizing Agents; Tirapazamine; Triazines | 1992 |
Evaluation of bioreductive drugs in multicell spheroids.
Topics: Animals; Antineoplastic Agents; Cell Aggregation; Cell Hypoxia; Cell Survival; Cricetinae; Evaluation Studies as Topic; In Vitro Techniques; Misonidazole; Mitomycin; Models, Biological; Nitrofurans; Porfiromycin; Prodrugs; Tirapazamine; Triazines | 1992 |
Bioreductive drugs as post-irradiation sensitizers: comparison of dual function agents with SR 4233 and the mitomycin C analogue EO9.
Topics: Animals; Antineoplastic Agents; Aziridines; Cell Hypoxia; Cell Survival; Combined Modality Therapy; Dose-Response Relationship, Drug; Indolequinones; Indoles; Mice; Mice, Inbred C3H; Misonidazole; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Prodrugs; Tirapazamine; Triazines | 1992 |
Mechanism of oncogenicity for bioreductive drugs.
Topics: Animals; Antineoplastic Agents; Aziridines; Cell Hypoxia; Cell Line; Cell Transformation, Neoplastic; Mice; Misonidazole; Neoplasms, Second Primary; Nitrofurans; Prodrugs; Radiation-Sensitizing Agents; Risk; Tirapazamine; Triazines | 1992 |
Hypobaric hypoxia: a method for testing bioreductive drugs in vivo.
Topics: Animals; Biotransformation; Cell Hypoxia; Dose-Response Relationship, Drug; Mammary Neoplasms, Experimental; Mechlorethamine; Mice; Mice, Inbred Strains; Misonidazole; Radiation-Sensitizing Agents; Tirapazamine; Triazines | 1992 |
Bioreductive drugs and the selective induction of tumour hypoxia.
Topics: Animals; Antineoplastic Agents; Cell Hypoxia; Constriction; Hydralazine; Mice; Mice, Inbred C3H; Misonidazole; Mitomycin; Mitomycins; Radiation-Sensitizing Agents; Sarcoma, Experimental; Tirapazamine; Triazines | 1990 |
The effects of three bioreductive drugs (mitomycin C, RSU-1069 and SR4233) on cell lines selected for their sensitivity to mitomycin C or ionising radiation.
Topics: Animals; Antineoplastic Agents; Cell Hypoxia; Cell Line; Cell Survival; Misonidazole; Mitomycin; Mitomycins; Radiation Tolerance; Radiation-Sensitizing Agents; Tirapazamine; Triazines | 1990 |
Use of the comet assay to detect hypoxic cells in murine tumours and normal tissues exposed to bioreductive drugs.
Topics: Aerobiosis; Animals; Antineoplastic Agents; Bone Marrow; Carcinoma, Squamous Cell; Cell Hypoxia; DNA Damage; DNA, Single-Stranded; Dose-Response Relationship, Radiation; Electrophoresis, Agar Gel; Hydrogen-Ion Concentration; Male; Mice; Mice, Inbred C3H; Misonidazole; Organ Specificity; Oxidation-Reduction; Radiation-Sensitizing Agents; Spleen; Tirapazamine; Triazines | 1995 |
Unusual oxygen concentration dependence of toxicity of SR-4233, a hypoxic cell toxin.
Topics: Animals; Cell Hypoxia; Cell Line; Cricetinae; Cricetulus; Fibroblasts; Misonidazole; Oxygen; Radiation-Sensitizing Agents; Tirapazamine; Triazines | 1993 |
Overexpression of human NADPH:cytochrome c (P450) reductase confers enhanced sensitivity to both tirapazamine (SR 4233) and RSU 1069.
Topics: Antineoplastic Agents; Breast Neoplasms; Female; Humans; Misonidazole; NADPH-Ferrihemoprotein Reductase; Radiation-Sensitizing Agents; Tirapazamine; Transfection; Triazines; Tumor Cells, Cultured | 1997 |
Bioreductive therapies: an overview of drugs and their mechanisms of action.
Topics: Animals; Antineoplastic Agents; Aziridines; Cell Hypoxia; DNA, Neoplasm; Forecasting; Humans; Indolequinones; Indoles; Misonidazole; Mitomycin; Nitrofurans; Nitroimidazoles; Oxidation-Reduction; Prodrugs; Radiation-Sensitizing Agents; Tirapazamine; Triazines | 1998 |