Compounds > 1-(2-nitro-1-imidazolyl)-3-aziridino-2-propanol
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1-(2-nitro-1-imidazolyl)-3-aziridino-2-propanol and rsu 1131

1-(2-nitro-1-imidazolyl)-3-aziridino-2-propanol has been researched along with rsu 1131 in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19903 (60.00)18.7374
1990's2 (40.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Adams, GE; Fielden, EM; Naylor, MA; Stephens, MA; Stratford, IJ; Threadgill, MD; Webb, P1
Jenner, TJ; Maggi, A; O'Neill, P; Paone, A; Sapora, O1
Fielden, EM; Jenner, TJ; O'Neill, P; Sapora, O1
Adams, GE; Stephens, MA; Stratford, IJ; Walling, J1
Jenkins, TC; McNeil, SS; O'Neill, P1

Other Studies

5 other study(ies) available for 1-(2-nitro-1-imidazolyl)-3-aziridino-2-propanol and rsu 1131

ArticleYear
2-Nitroimidazole dual-function bioreductive drugs: studies on the effects of regioisomerism and side-chain structural modifications on differential cytotoxicity and radiosensitization by aziridinyl and oxiranyl derivatives.
    Journal of medicinal chemistry, 1992, Sep-18, Volume: 35, Issue:19

    Topics: Antibiotics, Antineoplastic; Aziridines; Isomerism; Nitroimidazoles; Radiation Tolerance; Structure-Activity Relationship; Tumor Cells, Cultured

1992
Induction of mutations in V79-4 mammalian cells under hypoxic and aerobic conditions by the cytotoxic 2-nitroimidazole-aziridines, RSU-1069 and RSU-1131. The influence of cellular glutathione.
    Biochemical pharmacology, 1992, Oct-06, Volume: 44, Issue:7

    Topics: Animals; Aziridines; Buthionine Sulfoximine; Cell Hypoxia; Cell Line; Cell Survival; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Glutathione; Methionine Sulfoximine; Misonidazole; Mutagenicity Tests; Mutation; Oxidation-Reduction; Oxygen; Thioguanine

1992
Enhancement of DNA damage in mammalian cells upon bioreduction of the nitroimidazole-aziridines RSU-1069 and RSU-1131.
    Biochemical pharmacology, 1988, Oct-15, Volume: 37, Issue:20

    Topics: Antineoplastic Agents; Cell Survival; Cells, Cultured; Cross-Linking Reagents; DNA; DNA Damage; Misonidazole; Oxidation-Reduction; Oxygen; Radiation-Sensitizing Agents

1988
Dual-function radiation sensitizers and bioreductive drugs: factors affecting cellular uptake and sensitizing efficiency in analogues of RSU 1069.
    International journal of radiation biology and related studies in physics, chemistry, and medicine, 1988, Volume: 53, Issue:4

    Topics: Animals; Cell Line; Cricetinae; Misonidazole; Radiation-Sensitizing Agents

1988
Induction of DNA crosslinks in vitro upon reduction of the nitroimidazole-aziridines RSU-1069 and RSU-1131.
    Biochemical pharmacology, 1987, Jun-01, Volume: 36, Issue:11

    Topics: Deoxyribonucleotides; DNA; DNA Damage; Kinetics; Misonidazole; Plasmids; Radiation-Sensitizing Agents; Structure-Activity Relationship

1987