1-(2-nitro-1-imidazoly)-3-(2,3-dimethylaziridino)-2-propanol has been researched along with 1-(2-nitro-1-imidazolyl)-3-aziridino-2-propanol in 9 studies
| Studies (1-(2-nitro-1-imidazoly)-3-(2,3-dimethylaziridino)-2-propanol) | Trials (1-(2-nitro-1-imidazoly)-3-(2,3-dimethylaziridino)-2-propanol) | Recent Studies (post-2010) (1-(2-nitro-1-imidazoly)-3-(2,3-dimethylaziridino)-2-propanol) | Studies (1-(2-nitro-1-imidazolyl)-3-aziridino-2-propanol) | Trials (1-(2-nitro-1-imidazolyl)-3-aziridino-2-propanol) | Recent Studies (post-2010) (1-(2-nitro-1-imidazolyl)-3-aziridino-2-propanol) |
|---|---|---|---|---|---|
| 19 | 0 | 0 | 110 | 3 | 1 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (33.33) | 18.7374 |
| 1990's | 6 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Siemann, DW; Sutherland, RM | 1 |
| Siemann, DW | 1 |
| Hall, EJ; He, ZY; Hei, TK; Piao, CQ | 2 |
| Adams, GE; Cole, S; Fielden, EM; Jenkins, TC; Stratford, IJ | 1 |
| Hall, EJ; Pirro, JP; Roizin-Towle, L | 1 |
| Deacon, J; Holliday, S; Stratford, IJ; Walling, JM | 1 |
| Adams, GE; Stephens, MA; Stratford, IJ; Walling, J | 1 |
| Ahmed, I; Deacon, JM; Holliday, SB; Jenkins, TC | 1 |
9 other study(ies) available for 1-(2-nitro-1-imidazoly)-3-(2,3-dimethylaziridino)-2-propanol and 1-(2-nitro-1-imidazolyl)-3-aziridino-2-propanol
| Article | Year |
|---|---|
Potentiation of alkylating chemotherapy by dual function nitrofurans in multi-cell spheroids and solid tumors.
Topics: Animals; Antineoplastic Agents; Aziridines; Bone Marrow; Carcinoma; Cell Survival; Dose-Response Relationship, Drug; Drug Synergism; Female; Humans; Lomustine; Mice; Mice, Inbred C3H; Mice, Inbred Strains; Misonidazole; Nitrofurans; Radiation-Sensitizing Agents; Sarcoma, Experimental; Stem Cells; Tumor Cells, Cultured | 1992 |
Cytotoxicity of dual function nitrofurans in rodent and human tumor cells.
Topics: Animals; Antineoplastic Agents; Aziridines; Cell Hypoxia; Cell Survival; Dose-Response Relationship, Drug; Humans; Mice; Misonidazole; Nitrofurans; Prodrugs; Radiation-Sensitizing Agents; Tumor Cells, Cultured | 1992 |
Mechanism of oncogenicity for bioreductive drugs.
Topics: Animals; Antineoplastic Agents; Aziridines; Cell Hypoxia; Cell Line; Cell Transformation, Neoplastic; Mice; Misonidazole; Neoplasms, Second Primary; Nitrofurans; Prodrugs; Radiation-Sensitizing Agents; Risk; Tirapazamine; Triazines | 1992 |
Dual-function 2-nitroimidazoles as hypoxic cell radiosensitizers and bioreductive cytotoxins: in vivo evaluation in KHT murine sarcomas.
Topics: Animals; Antineoplastic Agents; Female; Mice; Mice, Inbred C3H; Misonidazole; Prodrugs; Radiation-Sensitizing Agents; Sarcoma, Experimental | 1990 |
Studies with bifunctional bioreductive drugs. I. In vitro oncogenic transforming potential.
Topics: Animals; Antineoplastic Agents; Aziridines; Cell Line; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; In Vitro Techniques; Mice; Mice, Inbred Strains; Misonidazole; Nitrofurans; Radiation-Sensitizing Agents | 1990 |
Studies with bifunctional bioreductive drugs. II. Cytotoxicity assayed with A-549 lung carcinoma cells of human origin.
Topics: Antineoplastic Agents; Aziridines; Cell Line; Cell Survival; Humans; In Vitro Techniques; Lung Neoplasms; Misonidazole; Nitrofurans; Radiation-Sensitizing Agents | 1990 |
High uptake of RSU 1069 and its analogues melanotic melanomas.
Topics: Animals; Cell Line; Cell Membrane Permeability; Deoxyribonucleases; Drug Evaluation, Preclinical; Half-Life; Humans; Lung Neoplasms; Male; Melanoma; Mice; Mice, Inbred Strains; Microbial Collagenase; Misonidazole; Sarcoma, Experimental; Tissue Distribution; Trypsin; Tumor Cells, Cultured | 1989 |
Dual-function radiation sensitizers and bioreductive drugs: factors affecting cellular uptake and sensitizing efficiency in analogues of RSU 1069.
Topics: Animals; Cell Line; Cricetinae; Misonidazole; Radiation-Sensitizing Agents | 1988 |
Experimental pharmacokinetics of RSU-1069 and its analogues: high tumor/plasma ratios.
Topics: Animals; Male; Melanoma; Mice; Mice, Inbred C57BL; Misonidazole; Neoplasm Transplantation; Radiation-Sensitizing Agents | 1986 |