Compounds > 1-(2-methoxyphenyl)piperazine

1-(2-methoxyphenyl)piperazine and 1-(3-trifluoromethylphenyl)piperazine

1-(2-methoxyphenyl)piperazine has been researched along with 1-(3-trifluoromethylphenyl)piperazine in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19903 (37.50)18.7374
1990's5 (62.50)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
el-Ashmawy, MB; Fischer, JB; Glennon, RA; Herndon, JL; Howie, KJ; Ismaiel, AM; Server, AC; Yousif, MY1
Baldy, WJ; Davis, CB; DiStefano, DL; Elgin, RJ; Fedde, CL; Kesslick, JM; Martin, GE; Mathiasen, JR; Scott, MK; Shank, RP1
Glennon, RA; Lyon, RA; Naiman, NA; Titeler, M1
Glennon, RA; Lyon, RA; Magee, PS; McKenney, JD; Titeler, M1
Hamblin, MW; Jose, PA; Metcalf, MA; Monsma, FJ; Shen, Y; Sibley, DR1
Carrupt, PA; Gaillard, P; Schambel, P; Testa, B1
Abdel-Rahman, AA; Dukat, M; Glennon, RA; Gyermek, L; Ingher, S; Ismaiel, AM; Teitler, M1
Beneitez, ME; Benhamú, B; Fuentes, JA; López-Rodríguez, ML; Manzanares, J; Morcillo, MJ; Orensanz, L; Rosado, ML; Sanz, AM1

Other Studies

8 other study(ies) available for 1-(2-methoxyphenyl)piperazine and 1-(3-trifluoromethylphenyl)piperazine

ArticleYear
Novel 1-phenylpiperazine and 4-phenylpiperidine derivatives as high-affinity sigma ligands.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:12

    Topics: Animals; Guinea Pigs; In Vitro Techniques; Ligands; Piperazines; Piperidines; Radioligand Assay; Receptors, Dopamine; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Phencyclidine; Receptors, sigma; Structure-Activity Relationship

1991
Activity of aromatic substituted phenylpiperazines lacking affinity for dopamine binding sites in a preclinical test of antipsychotic efficacy.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:5

    Topics: Animals; Antipsychotic Agents; Avoidance Learning; Dose-Response Relationship, Drug; Piperazines; Rats; Receptors, Dopamine; Receptors, Serotonin; Structure-Activity Relationship

1989
Arylpiperazine derivatives as high-affinity 5-HT1A serotonin ligands.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:10

    Topics: Animals; Chemical Phenomena; Chemistry; Male; Piperazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Structure-Activity Relationship

1988
Synthesis and evaluation of phenyl- and benzoylpiperazines as potential serotonergic agents.
    Journal of medicinal chemistry, 1986, Volume: 29, Issue:5

    Topics: Animals; Computers; Kinetics; Magnetic Resonance Spectroscopy; Models, Molecular; Piperazines; Rats; Receptors, Serotonin; Serotonin

1986
Molecular cloning and expression of a 5-hydroxytryptamine7 serotonin receptor subtype.
    The Journal of biological chemistry, 1993, Aug-25, Volume: 268, Issue:24

    Topics: Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Cell Line; Cell Membrane; Cloning, Molecular; Cyclic AMP; Gene Expression; Kidney Tubules, Proximal; Lysergic Acid Diethylamide; Molecular Sequence Data; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Radioligand Assay; Rats; Receptors, Serotonin; Recombinant Proteins; Serotonin; Transfection

1993
Binding of arylpiperazines, (aryloxy)propanolamines, and tetrahydropyridylindoles to the 5-HT1A receptor: contribution of the molecular lipophilicity potential to three-dimensional quantitative structure-affinity relationship models.
    Journal of medicinal chemistry, 1996, Jan-05, Volume: 39, Issue:1

    Topics: Indoles; Ligands; Models, Molecular; Molecular Conformation; Molecular Structure; Piperazines; Propanolamines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Structure-Activity Relationship; Tetrahydronaphthalenes

1996
Structure-activity relationships for the binding of arylpiperazines and arylbiguanides at 5-HT3 serotonin receptors.
    Journal of medicinal chemistry, 1996, Sep-27, Volume: 39, Issue:20

    Topics: Animals; Biguanides; Heart Rate; Male; Molecular Structure; Muscle Contraction; Piperazines; Rabbits; Rats; Receptors, Serotonin; Reflex; Serotonin Antagonists; Serotonin Receptor Agonists; Structure-Activity Relationship; Urinary Bladder

1996
Synthesis and structure-activity relationships of a new model of arylpiperazines. 1. 2-[[4-(o-methoxyphenyl)piperazin-1-yl]methyl]-1, 3-dioxoperhydroimidazo[1,5-alpha]pyridine: a selective 5-HT1A receptor agonist.
    Journal of medicinal chemistry, 1996, Oct-25, Volume: 39, Issue:22

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Body Temperature; Cerebral Cortex; Kinetics; Mice; Piperazines; Raclopride; Rats; Receptor, Serotonin, 5-HT2A; Receptors, Adrenergic, alpha-1; Receptors, Dopamine D2; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Salicylamides; Serotonin Receptor Agonists; Social Behavior; Structure-Activity Relationship

1996