1-(2-methoxyphenyl)piperazine and 1-(1-naphthyl)piperazine

1-(2-methoxyphenyl)piperazine has been researched along with 1-(1-naphthyl)piperazine in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19901 (11.11)18.7374
1990's5 (55.56)18.2507
2000's2 (22.22)29.6817
2010's1 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
el-Ashmawy, MB; Fischer, JB; Glennon, RA; Herndon, JL; Howie, KJ; Ismaiel, AM; Server, AC; Yousif, MY1
Glennon, RA; Lyon, RA; Naiman, NA; Titeler, M1
IJzerman, AP; Kruse, CG; Kuipers, W; ter Horst-van Amstel, M; Tulp, MT; van Wijngaarden, I1
Hamblin, MW; Jose, PA; Metcalf, MA; Monsma, FJ; Shen, Y; Sibley, DR1
Carrupt, PA; Gaillard, P; Schambel, P; Testa, B1
Abdel-Rahman, AA; Dukat, M; Glennon, RA; Gyermek, L; Ingher, S; Ismaiel, AM; Teitler, M1
Grol, CJ; Schmidt, AW; Sprouse, JS; Vermeulen, ES; Wikström, HV1
Dukat, M; Glennon, RA; Lee, M; Pullagurla, MR; Rangisetty, JB; Roth, BL; Setola, V1
Berardi, F; Caroli, A; Colabufo, NA; Contino, M; De Giorgio, P; Di Pilato, P; Hedlund, PB; Lacivita, E; Leopoldo, M; Niso, M; Patarnello, D; Perrone, R; Stroth, N; Svenningsson, P1

Other Studies

9 other study(ies) available for 1-(2-methoxyphenyl)piperazine and 1-(1-naphthyl)piperazine

ArticleYear
Novel 1-phenylpiperazine and 4-phenylpiperidine derivatives as high-affinity sigma ligands.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:12

    Topics: Animals; Guinea Pigs; In Vitro Techniques; Ligands; Piperazines; Piperidines; Radioligand Assay; Receptors, Dopamine; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Phencyclidine; Receptors, sigma; Structure-Activity Relationship

1991
Arylpiperazine derivatives as high-affinity 5-HT1A serotonin ligands.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:10

    Topics: Animals; Chemical Phenomena; Chemistry; Male; Piperazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Structure-Activity Relationship

1988
N4-unsubstituted N1-arylpiperazines as high-affinity 5-HT1A receptor ligands.
    Journal of medicinal chemistry, 1995, May-26, Volume: 38, Issue:11

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amino Acid Sequence; Animals; Binding Sites; Chemical Phenomena; Chemistry, Physical; Molecular Conformation; Molecular Sequence Data; Molecular Structure; Piperazines; Protein Conformation; Radioligand Assay; Rats; Receptors, Serotonin; Serotonin Receptor Agonists; Structure-Activity Relationship

1995
Molecular cloning and expression of a 5-hydroxytryptamine7 serotonin receptor subtype.
    The Journal of biological chemistry, 1993, Aug-25, Volume: 268, Issue:24

    Topics: Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Cell Line; Cell Membrane; Cloning, Molecular; Cyclic AMP; Gene Expression; Kidney Tubules, Proximal; Lysergic Acid Diethylamide; Molecular Sequence Data; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Radioligand Assay; Rats; Receptors, Serotonin; Recombinant Proteins; Serotonin; Transfection

1993
Binding of arylpiperazines, (aryloxy)propanolamines, and tetrahydropyridylindoles to the 5-HT1A receptor: contribution of the molecular lipophilicity potential to three-dimensional quantitative structure-affinity relationship models.
    Journal of medicinal chemistry, 1996, Jan-05, Volume: 39, Issue:1

    Topics: Indoles; Ligands; Models, Molecular; Molecular Conformation; Molecular Structure; Piperazines; Propanolamines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Structure-Activity Relationship; Tetrahydronaphthalenes

1996
Structure-activity relationships for the binding of arylpiperazines and arylbiguanides at 5-HT3 serotonin receptors.
    Journal of medicinal chemistry, 1996, Sep-27, Volume: 39, Issue:20

    Topics: Animals; Biguanides; Heart Rate; Male; Molecular Structure; Muscle Contraction; Piperazines; Rabbits; Rats; Receptors, Serotonin; Reflex; Serotonin Antagonists; Serotonin Receptor Agonists; Structure-Activity Relationship; Urinary Bladder

1996
Characterization of the 5-HT(7) receptor. Determination of the pharmacophore for 5-HT(7) receptor agonism and CoMFA-based modeling of the agonist binding site.
    Journal of medicinal chemistry, 2003, Dec-04, Volume: 46, Issue:25

    Topics: Binding Sites; Ligands; Models, Molecular; Quantitative Structure-Activity Relationship; Receptors, Serotonin; Serotonin Receptor Agonists; Tetrahydronaphthalenes; Tryptamines

2003
1-(1-Naphthyl)piperazine as a novel template for 5-HT6 serotonin receptor ligands.
    Bioorganic & medicinal chemistry letters, 2005, Mar-15, Volume: 15, Issue:6

    Topics: Ligands; Models, Chemical; Molecular Structure; Piperazines; Protein Binding; Receptors, Serotonin; Structure-Activity Relationship; Tryptamines

2005
Investigations on the 1-(2-biphenyl)piperazine motif: identification of new potent and selective ligands for the serotonin(7) (5-HT(7)) receptor with agonist or antagonist action in vitro or ex vivo.
    Journal of medicinal chemistry, 2012, Jul-26, Volume: 55, Issue:14

    Topics: Animals; Guinea Pigs; HeLa Cells; Humans; Ileum; Ligands; Models, Molecular; Molecular Weight; Piperazine; Piperazines; Protein Conformation; Receptors, Adrenergic, alpha-1; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Structure-Activity Relationship; Substrate Specificity

2012