Compounds > 1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine
Page last updated: 2024-09-02

1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine and topotecan

1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine has been researched along with topotecan in 1 studies

Compound Research Comparison

Studies
(1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine)		Trials
(1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine)		Recent Studies (post-2010)
(1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine)		Studies
(topotecan)		Trials
(topotecan)		Recent Studies (post-2010) (topotecan)
9022,392626792

Protein Interaction Comparison

ProteinTaxonomy1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine (IC50)topotecan (IC50)
Cytochrome P450 3A4Homo sapiens (human)1.5211
DNA topoisomerase 1Homo sapiens (human)0.8525
DNA topoisomerase 2-alphaHomo sapiens (human)0.605
DNA topoisomerase 2-betaHomo sapiens (human)0.605
Hypoxia-inducible factor 1-alphaHomo sapiens (human)0.06
Multidrug and toxin extrusion protein 2Homo sapiens (human)8.6
Multidrug and toxin extrusion protein 1Homo sapiens (human)1.3
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)0.17

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Budillon, A; Caliendo, G; De Angelis, F; Di Cintio, A; Di Gennaro, E; Esposito, A; Fiorino, F; Frecentese, F; Incisivo, GM; Magli, E; Massarelli, P; Nencini, C; Perissutti, E; Santagada, V; Severino, B1

Other Studies

1 other study(ies) available for 1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine and topotecan

ArticleYear
Synthesis of 1-naphtylpiperazine derivatives as serotoninergic ligands and their evaluation as antiproliferative agents.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:6

    Topics: Antineoplastic Agents; Cell Cycle; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Ligands; Male; Molecular Structure; Naphthalenes; Piperazines; Prostatic Neoplasms; Receptor, Serotonin, 5-HT1A; Stereoisomerism; Structure-Activity Relationship; Tumor Cells, Cultured

2011