1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine has been researched along with terfenadine in 2 studies
| Studies (1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine) | Trials (1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine) | Recent Studies (post-2010) (1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine) | Studies (terfenadine) | Trials (terfenadine) | Recent Studies (post-2010) (terfenadine) |
|---|---|---|---|---|---|
| 9 | 0 | 2 | 1,751 | 568 | 346 |
| 9 | 0 | 2 | 16 | 0 | 9 |
| Protein | Taxonomy | 1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine (IC50) | terfenadine (IC50) |
|---|---|---|---|
| Voltage-dependent L-type calcium channel subunit alpha-1F | Homo sapiens (human) | 0.93 | |
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 1.231 | |
| Epidermal growth factor receptor | Homo sapiens (human) | 3.566 | |
| Tyrosine-protein kinase Fyn | Homo sapiens (human) | 6.123 | |
| ATP-dependent translocase ABCB1 | Mus musculus (house mouse) | 2 | |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | 1.928 | |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | 1.8167 | |
| Cytochrome P450 3A4 | Homo sapiens (human) | 0.32 | |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | 2.9 | |
| D(2) dopamine receptor | Homo sapiens (human) | 6.167 | |
| Dipeptidyl peptidase 4 | Rattus norvegicus (Norway rat) | 0.35 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 2.34 | |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | 3.748 | |
| D | Rattus norvegicus (Norway rat) | 0.1288 | |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.1288 | |
| Substance-K receptor | Homo sapiens (human) | 2.677 | |
| D(1A) dopamine receptor | Homo sapiens (human) | 2.673 | |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | 0.1288 | |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.1288 | |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | 2.34 | |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 1.928 | |
| Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | 0.1288 | |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | 2.34 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 0.255 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 1.231 | |
| Histamine H1 receptor | Cavia porcellus (domestic guinea pig) | 0.094 | |
| Alpha-1A adrenergic receptor | Homo sapiens (human) | 2.34 | |
| Histamine H1 receptor | Homo sapiens (human) | 0.0115 | |
| Alpha-1B adrenergic receptor | Homo sapiens (human) | 2.34 | |
| D(3) dopamine receptor | Homo sapiens (human) | 1.503 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 0.048 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 2.34 | |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | 1.306 | |
| Cytochrome P450 2J2 | Homo sapiens (human) | 8.1 | |
| C-C chemokine receptor type 5 | Homo sapiens (human) | 1.103 | |
| Voltage-dependent L-type calcium channel subunit alpha-1D | Homo sapiens (human) | 0.93 | |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | 0.255 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 0.2233 | |
| Voltage-dependent L-type calcium channel subunit alpha-1S | Homo sapiens (human) | 0.93 | |
| Voltage-dependent L-type calcium channel subunit alpha-1C | Homo sapiens (human) | 1.125 | |
| Sodium channel protein type 5 subunit alpha | Homo sapiens (human) | 0.971 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
2 other study(ies) available for 1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine and terfenadine
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |