1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine has been researched along with ketoconazole in 2 studies
| Studies (1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine) | Trials (1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine) | Recent Studies (post-2010) (1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine) | Studies (ketoconazole) | Trials (ketoconazole) | Recent Studies (post-2010) (ketoconazole) |
|---|---|---|---|---|---|
| 9 | 0 | 2 | 6,202 | 706 | 1,269 |
| Protein | Taxonomy | 1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine (IC50) | ketoconazole (IC50) |
|---|---|---|---|
| Solute carrier family 22 member 1 | Homo sapiens (human) | 2.6 | |
| 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial | Homo sapiens (human) | 0.34 | |
| 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial | Mus musculus (house mouse) | 0.36 | |
| Bile salt export pump | Homo sapiens (human) | 3.44 | |
| Steroid 17-alpha-hydroxylase/17,20 lyase | Homo sapiens (human) | 1.5811 | |
| ATP-dependent translocase ABCB1 | Mus musculus (house mouse) | 6.7 | |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | 4.6771 | |
| Cytochrome P450 3A4 | Homo sapiens (human) | 0.1969 | |
| Steroid 21-hydroxylase | Homo sapiens (human) | 6.655 | |
| Cytochrome P450 2C8 | Homo sapiens (human) | 0.06 | |
| Aromatase | Homo sapiens (human) | 1.4111 | |
| Steroid 17-alpha-hydroxylase/17,20 lyase | Rattus norvegicus (Norway rat) | 2.0802 | |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Oryctolagus cuniculus (rabbit) | 5.425 | |
| Cholesterol side-chain cleavage enzyme, mitochondrial | Rattus norvegicus (Norway rat) | 3.32 | |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | 1.067 | |
| Cytochrome P450 2A2 | Rattus norvegicus (Norway rat) | 0.456 | |
| Cytochrome P450 11B1, mitochondrial | Bos taurus (cattle) | 0.38 | |
| Cytochrome P450 11B1, mitochondrial | Homo sapiens (human) | 0.162 | |
| Translocator protein | Rattus norvegicus (Norway rat) | 3.76 | |
| Cytochrome P450 7A1 | Rattus norvegicus (Norway rat) | 1.2975 | |
| Cytochrome P450 11B2, mitochondrial | Homo sapiens (human) | 0.5179 | |
| ATP-dependent translocase ABCB1 | Mus musculus (house mouse) | 3.8 | |
| Thromboxane-A synthase | Homo sapiens (human) | 2.165 | |
| Gonadotropin-releasing hormone receptor | Rattus norvegicus (Norway rat) | 2 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 0.531 | |
| Type-1 angiotensin II receptor | Oryctolagus cuniculus (rabbit) | 0.0078 | |
| Cytochrome P450 4F2 | Homo sapiens (human) | 1.6 | |
| 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial | Homo sapiens (human) | 0.4144 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 1.9036 | |
| Lanosterol 14-alpha demethylase | Homo sapiens (human) | 0.19 | |
| Cytochrome P450 7A1 | Mus musculus (house mouse) | 1.2975 | |
| Lanosterol 14-alpha demethylase | Rattus norvegicus (Norway rat) | 0.083 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
2 other study(ies) available for 1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine and ketoconazole
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |