Page last updated: 2024-09-02

1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine and cinnarizine

1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine has been researched along with cinnarizine in 2 studies

Compound Research Comparison

Studies
(1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine)
Trials
(1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine)
Recent Studies (post-2010)
(1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine)
Studies
(cinnarizine)
Trials
(cinnarizine)
Recent Studies (post-2010) (cinnarizine)
902855148190

Protein Interaction Comparison

ProteinTaxonomy1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine (IC50)cinnarizine (IC50)
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)2.832
Muscarinic acetylcholine receptor M4Homo sapiens (human)3.66
Muscarinic acetylcholine receptor M5Homo sapiens (human)0.759
Alpha-2A adrenergic receptorHomo sapiens (human)0.444
Muscarinic acetylcholine receptor M1Homo sapiens (human)2.513
D(2) dopamine receptorHomo sapiens (human)0.776
Alpha-2B adrenergic receptorHomo sapiens (human)2.242
Alpha-2C adrenergic receptorHomo sapiens (human)0.652
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)1.083
Muscarinic acetylcholine receptor M3Homo sapiens (human)0.762
Sodium-dependent noradrenaline transporter Homo sapiens (human)2.832
Alpha-1D adrenergic receptorHomo sapiens (human)1.167
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.36
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)1.083
Sodium-dependent serotonin transporterHomo sapiens (human)1.09
Histamine H1 receptorHomo sapiens (human)0.074
Mu-type opioid receptorHomo sapiens (human)2.272
D(3) dopamine receptorHomo sapiens (human)0.252
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.731
Sodium-dependent dopamine transporter Homo sapiens (human)1.641
Sigma non-opioid intracellular receptor 1Homo sapiens (human)0.04

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J1

Other Studies

2 other study(ies) available for 1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine and cinnarizine

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
    Nature chemical biology, 2009, Volume: 5, Issue:10

    Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection

2009