Page last updated: 2024-09-02

1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine and brexanolone

1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine has been researched along with brexanolone in 2 studies

Compound Research Comparison

Studies
(1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine)
Trials
(1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine)
Recent Studies (post-2010)
(1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine)
Studies
(brexanolone)
Trials
(brexanolone)
Recent Studies (post-2010) (brexanolone)
90291561

Protein Interaction Comparison

ProteinTaxonomy1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine (IC50)brexanolone (IC50)
Gamma-aminobutyric acid receptor subunit piHomo sapiens (human)0.022
Gamma-aminobutyric acid receptor subunit piRattus norvegicus (Norway rat)0.0985
Gamma-aminobutyric acid receptor subunit deltaHomo sapiens (human)0.022
Gamma-aminobutyric acid receptor subunit alpha-1Homo sapiens (human)0.022
Gamma-aminobutyric acid receptor subunit beta-1Rattus norvegicus (Norway rat)0.0985
Gamma-aminobutyric acid receptor subunit beta-1Homo sapiens (human)0.022
Gamma-aminobutyric acid receptor subunit deltaRattus norvegicus (Norway rat)0.0985
Gamma-aminobutyric acid receptor subunit gamma-2Homo sapiens (human)0.022
Gamma-aminobutyric acid receptor subunit gamma-2Rattus norvegicus (Norway rat)0.0985
Gamma-aminobutyric acid receptor subunit alpha-5Rattus norvegicus (Norway rat)0.0985
Gamma-aminobutyric acid receptor subunit alpha-3Rattus norvegicus (Norway rat)0.0985
Gamma-aminobutyric acid receptor subunit gamma-1Rattus norvegicus (Norway rat)0.0985
Gamma-aminobutyric acid receptor subunit alpha-2Rattus norvegicus (Norway rat)0.0985
Sodium- and chloride-dependent GABA transporter 1Rattus norvegicus (Norway rat)0.091
Gamma-aminobutyric acid receptor subunit alpha-4Rattus norvegicus (Norway rat)0.0985
Gamma-aminobutyric acid receptor subunit beta-3Homo sapiens (human)0.022
Gamma-aminobutyric acid receptor subunit gamma-3Rattus norvegicus (Norway rat)0.0985
Gamma-aminobutyric acid receptor subunit alpha-6Rattus norvegicus (Norway rat)0.0985
Gamma-aminobutyric acid receptor subunit alpha-5Homo sapiens (human)0.022
Sodium- and chloride-dependent GABA transporter 2Rattus norvegicus (Norway rat)0.091
Sodium- and chloride-dependent GABA transporter 3Rattus norvegicus (Norway rat)0.091
Gamma-aminobutyric acid receptor subunit alpha-3Homo sapiens (human)0.022
Gamma-aminobutyric acid receptor subunit alpha-2Homo sapiens (human)0.022
Gamma-aminobutyric acid receptor subunit beta-2Homo sapiens (human)0.022
Sodium- and chloride-dependent betaine transporterRattus norvegicus (Norway rat)0.091
Gamma-aminobutyric acid receptor subunit alpha-4Homo sapiens (human)0.022
Gamma-aminobutyric acid receptor subunit alpha-1Mus musculus (house mouse)0.074
Gamma-aminobutyric acid receptor subunit alpha-1Rattus norvegicus (Norway rat)0.0985
Gamma-aminobutyric acid receptor subunit beta-3Rattus norvegicus (Norway rat)0.0985
Gamma-aminobutyric acid receptor subunit beta-2Rattus norvegicus (Norway rat)0.0985
Gamma-aminobutyric acid receptor subunit epsilonHomo sapiens (human)0.022
Gamma-aminobutyric acid receptor subunit alpha-6Homo sapiens (human)0.022
Gamma-aminobutyric acid receptor subunit gamma-1Homo sapiens (human)0.022
GABA theta subunitRattus norvegicus (Norway rat)0.0985
Gamma-aminobutyric acid receptor subunit gamma-3Homo sapiens (human)0.022
Gamma-aminobutyric acid receptor subunit epsilonRattus norvegicus (Norway rat)0.0985
Gamma-aminobutyric acid receptor subunit thetaHomo sapiens (human)0.022

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J1

Other Studies

2 other study(ies) available for 1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine and brexanolone

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
    Nature chemical biology, 2009, Volume: 5, Issue:10

    Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection

2009