Page last updated: 2024-09-03

1-(2-hydroxyethyl)-2-hydroxymethyl-5-nitroimidazole and omeprazole

1-(2-hydroxyethyl)-2-hydroxymethyl-5-nitroimidazole has been researched along with omeprazole in 1 studies

Compound Research Comparison

Studies
(1-(2-hydroxyethyl)-2-hydroxymethyl-5-nitroimidazole)
Trials
(1-(2-hydroxyethyl)-2-hydroxymethyl-5-nitroimidazole)
Recent Studies (post-2010)
(1-(2-hydroxyethyl)-2-hydroxymethyl-5-nitroimidazole)
Studies
(omeprazole)
Trials
(omeprazole)
Recent Studies (post-2010) (omeprazole)
29249,0852,7371,487

Protein Interaction Comparison

ProteinTaxonomy1-(2-hydroxyethyl)-2-hydroxymethyl-5-nitroimidazole (IC50)omeprazole (IC50)
Mcl-1Homo sapiens (human)3.1448
cGMP-specific 3',5'-cyclic phosphodiesteraseHomo sapiens (human)0.28
Potassium-transporting ATPase alpha chain 1Homo sapiens (human)1.45
Cytochrome P450 2C19Homo sapiens (human)2.315
Potassium-transporting ATPase subunit betaHomo sapiens (human)1.45
WD repeat-containing protein 5Homo sapiens (human)1.7
Glutathione S-transferase omega-1Homo sapiens (human)4.6
Histone-lysine N-methyltransferase 2AHomo sapiens (human)1.7
Muscarinic acetylcholine receptorCavia porcellus (domestic guinea pig)3.8

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barrett, DA; Goddard, AF; Jessa, MJ; Shaw, PN; Spiller, RC1

Trials

1 trial(s) available for 1-(2-hydroxyethyl)-2-hydroxymethyl-5-nitroimidazole and omeprazole

ArticleYear
The effect of omeprazole on the pharmacokinetics of metronidazole and hydroxymetronidazole in human plasma, saliva and gastric juice.
    British journal of clinical pharmacology, 1997, Volume: 44, Issue:3

    Topics: Adult; Anti-Ulcer Agents; Antitrichomonal Agents; Area Under Curve; Biological Availability; Cross-Over Studies; Double-Blind Method; Gastric Juice; Half-Life; Humans; Male; Metabolic Clearance Rate; Metronidazole; Omeprazole; Saliva

1997