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1-(2-chloroethyl)-3-(2,6-dioxo-3-piperidinyl)-1-nitrosourea and lomustine

1-(2-chloroethyl)-3-(2,6-dioxo-3-piperidinyl)-1-nitrosourea has been researched along with lomustine in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19908 (88.89)18.7374
1990's1 (11.11)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Johnston, TP; Laster, WR; Mayo, JG; McCaleb, GS; Montgomery, JA1
Dolan, ME; Weinkam, RJ1
Carter, RL; Frye, JL; Johnston, TP; Kussner, CL; Lomax, NR; Narayanan, VL; Plowman, J1
Levin, VA1
Hansch, C; Jow, PY; Leo, A; Montgomery, JA; Schmidt, C1
Brajtburg, J; Elberg, S; Medoff, G; Schechtman, KB1
Dean, PN; Deen, DF; Gray, JW; Linfoot, PA; Marton, LJ1
Erickson, LC; Kohn, KW; Sariban, E1
Deen, DF; Weinkam, RJ1

Other Studies

9 other study(ies) available for 1-(2-chloroethyl)-3-(2,6-dioxo-3-piperidinyl)-1-nitrosourea and lomustine

ArticleYear
Inhibition of solid tumors by nitrosoureas. 1. Lewis lung carcinoma.
    Journal of medicinal chemistry, 1977, Volume: 20, Issue:2

    Topics: Animals; Carcinoma; Leukemia L1210; Lung Neoplasms; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Nitrosourea Compounds; Structure-Activity Relationship; Time Factors

1977
An analysis of 1-(2-chloroethyl)-1-nitrosourea activity at the cellular level.
    Journal of medicinal chemistry, 1983, Volume: 26, Issue:11

    Topics: Animals; Antineoplastic Agents; Carmustine; Cell Survival; Drug Evaluation, Preclinical; Ethylnitrosourea; Leukemia L1210; Leukemia P388; Lomustine; Mice; Nitrosourea Compounds; Streptozocin; Structure-Activity Relationship

1983
Studies on synthesis and anticancer activity of selected N-(2-fluoroethyl)-N-nitrosoureas.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:11

    Topics: Animals; Antineoplastic Agents; Ethane; Hydrocarbons, Fluorinated; Melanoma; Mice; Nitrosourea Compounds

1984
Relationship of octanol/water partition coefficient and molecular weight to rat brain capillary permeability.
    Journal of medicinal chemistry, 1980, Volume: 23, Issue:6

    Topics: Animals; Blood-Brain Barrier; Brain; Capillary Permeability; Male; Models, Biological; Molecular Weight; Rats; Rats, Inbred F344; Solubility; Structure-Activity Relationship

1980
Antitumor structure-activity relations. Nitrosoureas vs. L-1210 leukemia.
    Journal of medicinal chemistry, 1980, Volume: 23, Issue:10

    Topics: Animals; Antineoplastic Agents; Leukemia L1210; Mice; Models, Theoretical; Nitrosourea Compounds; Solubility; Structure-Activity Relationship

1980
Lysis of human promyelocytic HL-60 cells by amphotericin B in combination with 2-chloroethyl-1-nitrosoureas: role of the carbamoylating activity of nitrosoureas.
    Cancer research, 1990, Jun-01, Volume: 50, Issue:11

    Topics: Amphotericin B; Carmustine; Cell Line; Drug Therapy, Combination; Glutathione; Humans; L-Lactate Dehydrogenase; Leukemia, Promyelocytic, Acute; Lomustine; Nitrosourea Compounds

1990
Effect of cell cycle position on the survival of 9L cells treated with nitrosoureas that alkylate, cross-link, and carbamoylate.
    Cancer research, 1986, Volume: 46, Issue:5

    Topics: Alkylating Agents; Animals; Brain Neoplasms; Carbamates; Carmustine; Cell Cycle; Cell Line; Cell Survival; Cross-Linking Reagents; Ethylnitrosourea; Lomustine; Nitroso Compounds; Nitrosourea Compounds; Rats; Structure-Activity Relationship

1986
Effects of carbamoylation on cell survival and DNA repair in normal human embryo cells (IMR-90) treated with various 1-(2-chloroethyl)-1-nitrosoureas.
    Cancer research, 1984, Volume: 44, Issue:4

    Topics: Carmustine; Cell Line; Cell Survival; DNA; DNA Repair; DNA Replication; Ethylnitrosourea; Female; Humans; Lomustine; Lung; Nitrosourea Compounds; Pregnancy; Structure-Activity Relationship

1984
Quantitative dose-response relations for the cytotoxic activity of chloroethylnitrosoureas in cell culture.
    Cancer research, 1982, Volume: 42, Issue:3

    Topics: Animals; Biotransformation; Brain Neoplasms; Carmustine; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Lomustine; Mustard Compounds; Neoplasms, Experimental; Nitrosourea Compounds; Rats; Semustine; Structure-Activity Relationship; Time Factors

1982