1-(2-chloroethyl)-3-(2,6-dioxo-3-piperidinyl)-1-nitrosourea has been researched along with carmustine in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (68.75) | 18.7374 |
| 1990's | 5 (31.25) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Johnston, TP; Laster, WR; Mayo, JG; McCaleb, GS; Montgomery, JA | 1 |
| Dolan, ME; Weinkam, RJ | 1 |
| Levin, VA | 1 |
| Hansch, C; Jow, PY; Leo, A; Montgomery, JA; Schmidt, C | 1 |
| Shapiro, WR | 1 |
| Bigner, DD; Bodell, WJ; Elion, GB; Friedman, HS; Schold, SC; Wang, AM | 1 |
| Brajtburg, J; Elberg, S; Medoff, G; Schechtman, KB | 1 |
| Carrasco, CH; Charnsangavej, C; Feun, LG; Gianturco, C; Lee, YY; Savaraj, N; Wallace, S; Yung, WK | 1 |
| D'Incalci, M; Day, R; Erickson, LC; Kohn, KW; Kornblith, PL; Laurent, G; Sariban, E; Smith, BH; Zlotogorski, C | 1 |
| Dean, PN; Deen, DF; Gray, JW; Linfoot, PA; Marton, LJ | 1 |
| Kanter, PM; Schwartz, HS; West, CR | 1 |
| Erickson, LC; Kohn, KW; Sariban, E | 1 |
| Levin, VA; Liu, J; Weinkam, RJ | 1 |
| Deen, DF; Weinkam, RJ | 1 |
| Arusell, RM; Brown, LD; Buckner, JC; Dinapoli, RP; Earle, JD; Krook, JE; Maier, JA; O'Fallon, JR; Scheithauer, BW; Tschetter, LK | 1 |
| Buckner, JC; Cascino, TL; Dinapoli, RP; O'Fallon, JR; Schaefer, PL; Schomberg, P; Taylor, BV | 1 |
2 review(s) available for 1-(2-chloroethyl)-3-(2,6-dioxo-3-piperidinyl)-1-nitrosourea and carmustine
| Article | Year |
|---|---|
Chemotherapy of malignant gliomas: studies of the BTCG.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Cisplatin; Combined Modality Therapy; Fluorouracil; Glioma; Humans; Injections, Intra-Arterial; Injections, Intravenous; Nitrosourea Compounds; Prognosis; Survival Analysis | 1992 |
New drugs and new delivery techniques.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aziridines; Benzoquinones; Bleomycin; Brain Neoplasms; Carboplatin; Carmustine; Cisplatin; Etoposide; Humans; Infusions, Intra-Arterial; Interferons; Nitrosourea Compounds; Organoplatinum Compounds; Rats | 1985 |
4 trial(s) available for 1-(2-chloroethyl)-3-(2,6-dioxo-3-piperidinyl)-1-nitrosourea and carmustine
| Article | Year |
|---|---|
Chemotherapy of malignant gliomas: studies of the BTCG.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Cisplatin; Combined Modality Therapy; Fluorouracil; Glioma; Humans; Injections, Intra-Arterial; Injections, Intravenous; Nitrosourea Compounds; Prognosis; Survival Analysis | 1992 |
Comparative pharmacokinetics of 1-(2-chloroethyl)-3-(2,6-dioxo-1-piperidyl)-1-nitrosourea in rats and patients and extrapolation to clinical trials.
Topics: Animals; Carmustine; Clinical Trials as Topic; Drug Evaluation; Gas Chromatography-Mass Spectrometry; Humans; Kinetics; Mustard Compounds; Neoplasms; Nitrosourea Compounds; Rats | 1981 |
Phase III comparative evaluation of PCNU and carmustine combined with radiation therapy for high-grade glioma.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Combined Modality Therapy; Female; Glioma; Humans; Male; Middle Aged; Multivariate Analysis; Nitrosourea Compounds; Survival Analysis; Treatment Outcome | 1993 |
Effects of radiation and chemotherapy on cognitive function in patients with high-grade glioma.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Cognition; Cranial Irradiation; Disease Progression; Female; Glioma; Humans; Intelligence Tests; Interferon-alpha; Male; Middle Aged; Nitrosourea Compounds; Prospective Studies; Survival Rate | 1998 |
11 other study(ies) available for 1-(2-chloroethyl)-3-(2,6-dioxo-3-piperidinyl)-1-nitrosourea and carmustine
| Article | Year |
|---|---|
Inhibition of solid tumors by nitrosoureas. 1. Lewis lung carcinoma.
Topics: Animals; Carcinoma; Leukemia L1210; Lung Neoplasms; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Nitrosourea Compounds; Structure-Activity Relationship; Time Factors | 1977 |
An analysis of 1-(2-chloroethyl)-1-nitrosourea activity at the cellular level.
Topics: Animals; Antineoplastic Agents; Carmustine; Cell Survival; Drug Evaluation, Preclinical; Ethylnitrosourea; Leukemia L1210; Leukemia P388; Lomustine; Mice; Nitrosourea Compounds; Streptozocin; Structure-Activity Relationship | 1983 |
Relationship of octanol/water partition coefficient and molecular weight to rat brain capillary permeability.
Topics: Animals; Blood-Brain Barrier; Brain; Capillary Permeability; Male; Models, Biological; Molecular Weight; Rats; Rats, Inbred F344; Solubility; Structure-Activity Relationship | 1980 |
Antitumor structure-activity relations. Nitrosoureas vs. L-1210 leukemia.
Topics: Animals; Antineoplastic Agents; Leukemia L1210; Mice; Models, Theoretical; Nitrosourea Compounds; Solubility; Structure-Activity Relationship | 1980 |
Positive therapeutic interaction between thiopurines and alkylating drugs in human glioma xenografts.
Topics: Alkylating Agents; Animals; Antineoplastic Combined Chemotherapy Protocols; Carmustine; DNA; Glioma; Humans; Mercaptopurine; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Nitrosourea Compounds; Procarbazine; Survival Rate; Thioguanine; Transplantation, Heterologous | 1991 |
Lysis of human promyelocytic HL-60 cells by amphotericin B in combination with 2-chloroethyl-1-nitrosoureas: role of the carbamoylating activity of nitrosoureas.
Topics: Amphotericin B; Carmustine; Cell Line; Drug Therapy, Combination; Glutathione; Humans; L-Lactate Dehydrogenase; Leukemia, Promyelocytic, Acute; Lomustine; Nitrosourea Compounds | 1990 |
DNA cross-linking responses of human malignant glioma cell strains to chloroethylnitrosoureas, cisplatin, and diaziquone.
Topics: Aziridines; Benzoquinones; Brain Neoplasms; Carmustine; Cells, Cultured; Cisplatin; Cross-Linking Reagents; DNA Damage; DNA, Neoplasm; Drug Resistance; Ethylnitrosourea; Glioblastoma; Humans; Neoplasm Proteins; Nitrosourea Compounds | 1987 |
Effect of cell cycle position on the survival of 9L cells treated with nitrosoureas that alkylate, cross-link, and carbamoylate.
Topics: Alkylating Agents; Animals; Brain Neoplasms; Carbamates; Carmustine; Cell Cycle; Cell Line; Cell Survival; Cross-Linking Reagents; Ethylnitrosourea; Lomustine; Nitroso Compounds; Nitrosourea Compounds; Rats; Structure-Activity Relationship | 1986 |
Functional and chemical markers of PCNU activity.
Topics: Animals; Antineoplastic Agents; Carmustine; DNA; Humans; Leukemia; Mice; Nitrosourea Compounds; Phenobarbital; Thymidine | 1983 |
Effects of carbamoylation on cell survival and DNA repair in normal human embryo cells (IMR-90) treated with various 1-(2-chloroethyl)-1-nitrosoureas.
Topics: Carmustine; Cell Line; Cell Survival; DNA; DNA Repair; DNA Replication; Ethylnitrosourea; Female; Humans; Lomustine; Lung; Nitrosourea Compounds; Pregnancy; Structure-Activity Relationship | 1984 |
Quantitative dose-response relations for the cytotoxic activity of chloroethylnitrosoureas in cell culture.
Topics: Animals; Biotransformation; Brain Neoplasms; Carmustine; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Lomustine; Mustard Compounds; Neoplasms, Experimental; Nitrosourea Compounds; Rats; Semustine; Structure-Activity Relationship; Time Factors | 1982 |