1-(2-chloroethyl)-3-(2-(dimethylaminosulfonyl)ethyl)-1-nitrosourea and taurine

1-(2-chloroethyl)-3-(2-(dimethylaminosulfonyl)ethyl)-1-nitrosourea has been researched along with taurine in 55 studies

Research

Studies (55)

Timeframe	Studies, this research(%)	All Research%
pre-1990	26 (47.27)	18.7374
1990's	29 (52.73)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Baldvinsdóttir, J; Loftsson, T	1
Aapro, M; Demierre, B; Gregor, A; Ironside, JW; Malmström, P; Rampling, R; Rye, R; Sellar, R; Stewart, M; Whittle, IR	1
Hartley-Asp, B	1
Bibby, MC; Cox, JA; Crawford, SM; Quinn, PK	1
al-Ghabban, AF; Bibby, MC; Double, JA; Loadman, PM	1
Glover, DJ	1
Mason, C; Padwick, DJ; Panoutsopoulos, GI; Pearson, D; Smith, JA	1
Bach, F; Dombernowsky, P; Hansen, HH; Sørensen, JB; Vibe-Petersen, J	2
Franklin, HR; McVie, JG; Taal, BG; ten Bokkel Huinink, WW	1
MacPherson, JS; Miller, JD; Smyth, JF; Whittle, IR	1
Drings, P; Edler, L; Fiebig, HH; Gatzemeier, U; Hinke, A; Rieche, K; Tessen, HW	1
Grönquist, L; Gunnarsson, PO; Seidegård, J	1
Brandin, S; Gustafsson, B; Ottersgård-Brorsson, A; Polacek, J	1
Bach, F; Hansen, HH; Pedersen, AG; Smyth, J; Vibe-Petersen, J	1
Atassi, G; Dumont, P; Fournier, JP; Gosse, C; Gouyette, A; Roger, P	1
Bono, AV; De Pauw, M; Droz, JP; Fossa, ST; Keizer, J; Splinter, TA; Sylvester, R; Van Oosterom, AT; Verbaeys, AJ	1
Pratesi, G; Savi, G	1
Bergh, J; Blomquist, E; Gjedde, SB; Lindegaard-Madsen, E; Mouridsen, HT; Nolte, H	1
Gundersen, S; Pinedo, HM; Renard, J; Smyth, JF	1
Hartley-Asp, B; Kruse, E	1
Bruntsch, U; Cavalli, F; Dombernowsky, P; Gundersen, S; Pinedo, H; Renard, J; Van Glabbeke, M	1
Dexter, TM; Jelinek, J; Kleibl, K; Margison, GP	1
Ellman, M; Gunnarsson, PO; Hansen, HH; Macpherson, JS; Polacek, J; Smyth, JF; Vibe-Petersen, J; Warrington, PS	1
Dean, SW; Gibson, NW; Tew, KD	1
Christensen, IJ; Hansen, HH; Roed, H; Spang-Thomsen, M; Vindeløv, LL	1
Bibby, MC; Bloomer, JC; Double, JA; Loadman, PM	1
Bibby, MC; Double, JA; Morris, CM	1
Bibby, MC; Double, JA; Phillips, RM	1
Clavel, M; Dombernowsky, P; Howell, A; Pinedo, HM; Renard, J; Smyth, JF; van Glabekke, M	1
Hansen, M; Heaf, JG	1
Macpherson, JS; Miller, JD; Smyth, J; Whittle, IR	1
Workman, P	1
Brandin, S; Gunnarsson, PO; Polacek, J	1
Anderson, LE; Fergusson, RJ; Macpherson, JS; Robins, P; Smyth, JF	1
Christensson, PI; Gunnarsson, K; Gunnarsson, PO; Hartley-Asp, B; Jensen, G; Polacek, J; Stamvik, A	1
Bork, E; Hansen, HH; Møller, H; Vibe-Petersen, J	1
Cornbleet, MA; Kerr, ME; Leonard, RC; Macpherson, JS; Smyth, JF; Warrington, PS; Whelan, JM	1
Molineux, G; Schofield, R; Testa, NG	1
Balslev, I; Ernst, P; Mouridsen, HT	1
d'Argy, R; Gunnarsson, PO; Johansson, CJ; Lundin, N; Teder, H	1
Boot, H; Gortzak, E; Taal, BG; Van den Hout, BM; Zoetmulder, FA	1
Bergh, J; Blomquist, E; Gjedde, SB; Jensen, NV; L-Madsen, E; Mouridsen, HT; Söderberg, M; Wählby, S	2
Bibby, MC; Hill, SR	1
Belal, F; Hefnawy, MM; Metwally, ME; Walash, MI	1
Rodenhuis, S; Taal, BG; Ten Bokkel Huinink, WW	2
Bibby, MC; Loadman, PM; Matthew, AM; Phillips, RM	1
Chaudry, IH; Graffner, HO; Milsom, JW; Singh, G	1
Gunnarsson, PO; Seidegård, J; Tuvesson, H	2
Alderson, D; Denton, G; Grace, RH; Hardcastle, JD; Lauri, H; Mansi, JL; Nordle, O; Smyth, JF; Wählby, S; Yosef, HM	1
Ellman, M; Gunnarsson, PO; Hansen, HH; Hansson, K; Hartley-Asp, B; Polacek, J; Vibe-Petersen, J	1
Wils, J	1

Reviews

1 review(s) available for 1-(2-chloroethyl)-3-(2-(dimethylaminosulfonyl)ethyl)-1-nitrosourea and taurine

Article	Year
TCNU: a ray of hope for designer nitrosoureas? European journal of cancer & clinical oncology, 1987, Volume: 23, Issue:12 Topics: Antineoplastic Agents; Humans; Neoplasms; Nitrosourea Compounds; Taurine	1987

Trials

7 trial(s) available for 1-(2-chloroethyl)-3-(2-(dimethylaminosulfonyl)ethyl)-1-nitrosourea and taurine

Article	Year
Phase II study of tauromustine in malignant glioma. European journal of cancer (Oxford, England : 1990), 1992, Volume: 28A, Issue:12 Topics: Adult; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Drug Administration Schedule; Drug Evaluation; Female; Glioma; Humans; Leukopenia; Male; Middle Aged; Nausea; Nitrosourea Compounds; Prospective Studies; Taurine; Thrombocytopenia	1992
Chemotherapy with tauromustine in advanced non-small cell lung cancer. A trial of the Phase II Study Group of the Association for Medical Oncology of the German Cancer Society. Onkologie, 1990, Volume: 13, Issue:3 Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Drug Evaluation; Follow-Up Studies; Germany, West; Humans; Lung Neoplasms; Multicenter Studies as Topic; Neoplasm Metastasis; Nitrosourea Compounds; Survival Rate; Taurine	1990
Randomized phase II trial of TCNU versus mitozolomide in malignant melanoma. EORTC Early Clinical Trials Group. European journal of cancer & clinical oncology, 1989, Volume: 25, Issue:4 Topics: Adult; Aged; Antineoplastic Agents; Drug Evaluation; Female; Humans; Male; Melanoma; Middle Aged; Nitrogen Mustard Compounds; Nitrosourea Compounds; Random Allocation; Taurine	1989
Phase II study of tauromustine in disseminated malignant melanoma. European journal of cancer (Oxford, England : 1990), 1994, Volume: 30A, Issue:4 Topics: Adult; Aged; Antineoplastic Agents; Female; Humans; Male; Melanoma; Middle Aged; Nitrosourea Compounds; Taurine; Treatment Outcome	1994
Phase I study of tauromustine administered in a weekly schedule. European journal of cancer (Oxford, England : 1990), 1993, Volume: 29A, Issue:13 Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Drug Administration Schedule; Female; Humans; Leukopenia; Male; Melanoma; Middle Aged; Nitrosourea Compounds; Taurine; Thrombocytopenia	1993
Combination chemotherapy with tauromustine (TCNU), 5-fluorouracil and leucovorin in advanced colorectal carcinoma: a dose-finding study. Annals of oncology : official journal of the European Society for Medical Oncology, 1993, Volume: 4, Issue:1 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Dose-Response Relationship, Drug; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Nitrosourea Compounds; Prognosis; Taurine	1993
Two phase III trials of tauromustine (TCNU) in advanced colorectal cancer. Annals of oncology : official journal of the European Society for Medical Oncology, 1995, Volume: 6, Issue:9 Topics: Aged; Antineoplastic Agents; Colorectal Neoplasms; Female; Fluorouracil; Humans; Male; Middle Aged; Nitrosourea Compounds; Prognosis; Quality of Life; Regression Analysis; Survival Rate; Taurine; Treatment Failure	1995

Other Studies

47 other study(ies) available for 1-(2-chloroethyl)-3-(2-(dimethylaminosulfonyl)ethyl)-1-nitrosourea and taurine

Article	Year
Degradation of tauromustine (TCNU) in aqueous solutions. Acta pharmaceutica Nordica, 1992, Volume: 4, Issue:3 Topics: Antineoplastic Agents; Chemistry, Pharmaceutical; Drug Stability; Nitrosourea Compounds; Solutions; Taurine; Water	1992
Genotoxicity of tauromustine, a new water soluble taurine-based nitrosourea. I. Mutagenic and clastogenic activity of tauromustine in vitro. Mutagenesis, 1992, Volume: 7, Issue:6 Topics: Antineoplastic Agents; Cell Cycle; Chromosome Aberrations; Humans; In Vitro Techniques; Lomustine; Lymphocytes; Mutagenicity Tests; Mutagens; Nitrosourea Compounds; Salmonella typhimurium; Sister Chromatid Exchange; Taurine	1992
The influence of hydralazine on the vasculature, blood perfusion and chemosensitivity of MAC tumours. British journal of cancer, 1992, Volume: 66, Issue:2 Topics: Adenocarcinoma; Animals; Bone Marrow; Cell Division; Cell Line; Colonic Neoplasms; Hydralazine; Male; Melphalan; Mice; Mice, Inbred Strains; Nitrosourea Compounds; Radionuclide Imaging; Regional Blood Flow; Taurine; Tumor Stem Cell Assay	1992
Influence of hydralazine on the pharmacokinetics of tauromustine (TCNU) in mice. British journal of cancer, 1992, Volume: 65, Issue:3 Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Synergism; Glomerular Filtration Rate; Half-Life; Hydralazine; Injections, Intravenous; Insulin; Kidney; Liver; Lung; Metabolic Clearance Rate; Mice; Mice, Inbred Strains; Nitrosourea Compounds; Taurine; Tissue Distribution	1992
New approaches to the chemotherapy of melanoma. Oncology (Williston Park, N.Y.), 1991, Volume: 5, Issue:5 Topics: Alkaloids; Amifostine; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Marrow Transplantation; Carmustine; Cisplatin; Cyclophosphamide; Dacarbazine; Daunorubicin; Humans; Lomustine; Melanoma; Nitrosourea Compounds; Paclitaxel; Procarbazine; Tamoxifen; Taurine; Thiotepa; Vincristine; Vindesine	1991
Effects of melatonin on the release and production of blood leukocytes after administration of a novel taurine-based nitrosourea cytotoxic agent. Acta oncologica (Stockholm, Sweden), 1991, Volume: 30, Issue:6 Topics: Animals; Antineoplastic Agents; Cell Division; Circadian Rhythm; Female; Guinea Pigs; Leukocyte Count; Leukocytes; Male; Melatonin; Nitrosourea Compounds; Rats; Rats, Inbred Strains; Taurine	1991
Phase II trial of TCNU and vindesine in patients with adenocarcinoma of the lung. European journal of cancer (Oxford, England : 1990), 1990, Volume: 26, Issue:4 Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Evaluation; Female; Humans; Lung Neoplasms; Male; Middle Aged; Nitrosourea Compounds; Remission Induction; Taurine; Vindesine	1990
5-Fluorouracil plus tauromustine in advanced colorectal cancer: unexpected negative results. European journal of cancer (Oxford, England : 1990), 1990, Volume: 26, Issue:7 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Female; Fluorouracil; Humans; Male; Middle Aged; Nitrosourea Compounds; Taurine	1990
The disposition of TCNU (tauromustine) in human malignant glioma: pharmacokinetic studies and clinical implications. Journal of neurosurgery, 1990, Volume: 72, Issue:5 Topics: Adult; Aged; Antineoplastic Agents; Astrocytoma; Brain; Brain Neoplasms; Female; Glioblastoma; Humans; Intracranial Pressure; Male; Middle Aged; Nitrosourea Compounds; Taurine	1990
TCNU in adenocarcinoma of the lung: a phase II study with divided doses. Annals of oncology : official journal of the European Society for Medical Oncology, 1990, Volume: 1, Issue:4 Topics: Adenocarcinoma; Drug Evaluation; Female; Humans; Lung Neoplasms; Male; Nitrosourea Compounds; Taurine	1990
Metabolism of a novel nitrosourea, tauromustine, in the rat. Biochemical pharmacology, 1990, May-01, Volume: 39, Issue:9 Topics: Animals; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; In Vitro Techniques; Male; Microsomes; Nitrosourea Compounds; Rats; Rats, Inbred Strains; Taurine	1990
Determination of tauromustine and its demethylated metabolites in plasma and urine. Journal of chromatography, 1990, Mar-16, Volume: 526, Issue:1 Topics: Antineoplastic Agents; Chromatography, High Pressure Liquid; Humans; Nitrosourea Compounds; Taurine	1990
A phase II trial of TCNU in patients with squamous, adeno and large cell carcinoma of the lung. European journal of cancer & clinical oncology, 1989, Volume: 25, Issue:12 Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Drug Evaluation; Female; Humans; Lung Neoplasms; Male; Middle Aged; Nitrosourea Compounds; Taurine	1989
Characterization of the anti-tumour activity against solid tumours of a new nitrosoureido sugar: Cy 233. Cancer chemotherapy and pharmacology, 1989, Volume: 25, Issue:3 Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carmustine; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Male; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasm Transplantation; Nitrosourea Compounds; Taurine; Time Factors	1989
TCNU in advanced renal cancer. Phase II study in previously untreated patients from the EORTC Genito-Urinary Tract Cancer Cooperative Group. European journal of cancer & clinical oncology, 1989, Volume: 25, Issue:12 Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Renal Cell; Drug Evaluation; Female; Humans; Kidney Neoplasms; Male; Middle Aged; Nitrosourea Compounds; Taurine	1989
Effects of tauromustine, a water-soluble nitrosourea compound on NMU-1 murine lung tumor. Oncology, 1989, Volume: 46, Issue:2 Topics: Animals; Carmustine; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Nitrosourea Compounds; Taurine	1989
Phase II study of tauromustine in disseminated malignant melanoma. European journal of cancer & clinical oncology, 1989, Volume: 25, Issue:4 Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Drug Evaluation; Humans; Melanoma; Middle Aged; Nitrosourea Compounds; Taurine	1989
The effect of estramustine, nor-nitrogen mustard and tauromustine on macromolecular labelling in the human prostatic tumour cell line 1013L. Pharmacology & toxicology, 1989, Volume: 64, Issue:1 Topics: Affinity Labels; Biological Transport; Cell Survival; DNA, Neoplasm; Estramustine; Humans; Leucine; Macromolecular Substances; Male; Nitrogen Mustard Compounds; Nitrosourea Compounds; Nucleotides; Prostatic Neoplasms; RNA, Neoplasm; Taurine; Tumor Cells, Cultured	1989
TCNU (LS 2667), a new active drug in the treatment of advanced colorectal cancer. EORTC Early Clinical Trials Group. European journal of cancer & clinical oncology, 1989, Volume: 25, Issue:7 Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Colorectal Neoplasms; Drug Evaluation; Humans; Middle Aged; Nitrosourea Compounds; Taurine	1989
Transfection of murine multi-potent haemopoietic stem cells with an E. coli DNA alkyltransferase gene confers resistance to the toxic effects of alkylating agents. Carcinogenesis, 1988, Volume: 9, Issue:1 Topics: Alkyl and Aryl Transferases; Alkylating Agents; Animals; Deoxyribonuclease BamHI; Deoxyribonuclease EcoRI; DNA Restriction Enzymes; Drug Resistance; Escherichia coli; Fluorometry; Hematopoietic Stem Cells; Mechlorethamine; Methyl Methanesulfonate; Methylnitrosourea; Mice; Nitrogen Mustard Compounds; Nitrosourea Compounds; Plasmids; Taurine; Transfection; Transferases	1988
Pharmacokinetics of tauromustine in cancer patients. Phase I studies. Cancer chemotherapy and pharmacology, 1989, Volume: 23, Issue:3 Topics: Antineoplastic Agents; Dose-Response Relationship, Drug; Drug Evaluation; Humans; Neoplasms; Nitrosourea Compounds; Taurine	1989
The effect of a novel taurine nitrosourea, 1-(2-chloroethyl)-3-[2-(dimethylaminosulfonyl)ethyl]-1-nitrosour ea (TCNU) on cytotoxicity, DNA crosslinking and glutathione reductase in lung carcinoma cell lines. Cancer chemotherapy and pharmacology, 1987, Volume: 19, Issue:4 Topics: Animals; Cell Line; Cell Survival; DNA, Neoplasm; Glutathione Reductase; Humans; Lomustine; Lung Neoplasms; Mammary Neoplasms, Experimental; Nitrosourea Compounds; Rats; Streptozocin; Taurine	1987
In vitro evaluation of a new nitrosourea, TCNU, against human small cell lung cancer cell lines. Cancer chemotherapy and pharmacology, 1987, Volume: 19, Issue:4 Topics: Carcinoma, Small Cell; Carmustine; Cell Cycle; Cell Line; Colony-Forming Units Assay; Drug Evaluation, Preclinical; Flow Cytometry; Humans; Lung Neoplasms; Nitrosourea Compounds; Taurine; Tumor Stem Cell Assay	1987
Effects of routes of administration of TCNU on its plasma, tissue and tumour concentrations. European journal of cancer & clinical oncology, 1988, Volume: 24, Issue:8 Topics: Adenocarcinoma; Administration, Oral; Animals; Antineoplastic Agents; Biological Availability; Colonic Neoplasms; Injections, Intraperitoneal; Injections, Intravenous; Male; Mice; Neoplasm Transplantation; Nitrosourea Compounds; Taurine; Tissue Distribution	1988
Anti-tumour activity of TCNU in a panel of transplantable murine colon tumours. European journal of cancer & clinical oncology, 1988, Volume: 24, Issue:8 Topics: Adenocarcinoma; Administration, Oral; Animals; Antineoplastic Agents; Colonic Neoplasms; Dose-Response Relationship, Drug; Female; Injections, Intraperitoneal; Injections, Intravenous; Male; Mice; Neoplasm Transplantation; Nitrosourea Compounds; Taurine	1988
In vitro and in vivo responses of a panel of murine colon tumours to TCNU: a positive correlation. European journal of cancer & clinical oncology, 1988, Volume: 24, Issue:8 Topics: Animals; Antineoplastic Agents; Cell Division; Cell Line; Colonic Neoplasms; Colony-Forming Units Assay; Dose-Response Relationship, Drug; Mice; Neoplasm Transplantation; Nitrosourea Compounds; Taurine; Tumor Cells, Cultured	1988
Phase II study of TCNU in advanced breast cancer. European journal of cancer & clinical oncology, 1988, Volume: 24, Issue:8 Topics: Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Drug Evaluation; Female; Humans; Middle Aged; Nitrosourea Compounds; Taurine	1988
Treatment of refractory cancer-associated hypercalcemia with aminohydroxypropylidene diphosphonate. Acta medica Scandinavica, 1988, Volume: 224, Issue:3 Topics: Adenocarcinoma; Antineoplastic Agents; Diphosphonates; Female; Humans; Hypercalcemia; Lung Neoplasms; Middle Aged; Nitrosourea Compounds; Pamidronate; Taurine	1988
Experimental cerebral and plasma pharmacokinetic studies of TCNU: implications for brain tumour chemotherapy. British journal of neurosurgery, 1987, Volume: 1, Issue:3 Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Glioma; Male; Nitrosourea Compounds; Rats; Rats, Inbred Strains; Taurine	1987
Determination of tauromustine, a nitrosourea-based antitumour agent, in plasma by high-performance liquid chromatography. Journal of chromatography, 1988, Mar-18, Volume: 425, Issue:2 Topics: Administration, Oral; Animals; Antineoplastic Agents; Chromatography, High Pressure Liquid; Dogs; Humans; Hydrogen-Ion Concentration; Nitrosourea Compounds; Taurine	1988
Activity of a new nitrosourea (TCNU) in human lung cancer xenografts. British journal of cancer, 1988, Volume: 57, Issue:4 Topics: Animals; Antineoplastic Agents; Bronchial Neoplasms; DNA Ligases; Humans; Lung; Male; Mice; Mice, Inbred CBA; Neoplasm Transplantation; Nitrosourea Compounds; Taurine	1988
Anti-tumour, toxicological and pharmacokinetic properties of a novel taurine-based nitrosourea (TCNU). Investigational new drugs, 1988, Volume: 6, Issue:1 Topics: Animals; Antineoplastic Agents; Biotransformation; Blood Cell Count; Chromatography, High Pressure Liquid; Dogs; Female; Male; Mice; Nitrosourea Compounds; Rats; Rats, Inbred Strains; Taurine; Tumor Cells, Cultured	1988
A phase I clinical evaluation of 1-(2-chloroethyl)-3-[2-(dimethylaminosulphonyl)ethyl]-1-nitrosou rea (TCNU). European journal of cancer & clinical oncology, 1987, Volume: 23, Issue:12 Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Dose-Response Relationship, Drug; Drug Evaluation; Hematologic Diseases; Humans; Middle Aged; Neoplasms; Nitrosourea Compounds; Prohibitins; Taurine	1987
Phase I study of TCNU, a novel nitrosourea. European journal of cancer & clinical oncology, 1987, Volume: 23, Issue:12 Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Dose-Response Relationship, Drug; Drug Evaluation; Female; Hematologic Diseases; Humans; Male; Middle Aged; Nausea; Neoplasms; Nitrosourea Compounds; Taurine; Vomiting	1987
Hematopoietic effects of TCNU in mice. Cancer treatment reports, 1987, Volume: 71, Issue:9 Topics: Animals; Antineoplastic Agents; Female; Hematopoietic System; Lethal Dose 50; Male; Mice; Nitrosourea Compounds; Stem Cells; Taurine; Tumor Stem Cell Assay	1987
Second-line chemotherapy with tauromustine in metastatic breast cancer in postmenopausal women: a phase II study. Cancer treatment reports, 1987, Volume: 71, Issue:10 Topics: Adult; Aged; Breast Neoplasms; Drug Evaluation; Female; Humans; Menopause; Middle Aged; Neoplasm Metastasis; Nitrosourea Compounds; Taurine	1987
The effect of different dose levels of degradable starch microspheres (Spherex) on the distribution of a cytotoxic drug after regional administration to tumour-bearing rats. European journal of cancer (Oxford, England : 1990), 1995, Volume: 31A, Issue:10 Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carbon Radioisotopes; Colonic Neoplasms; Injections, Intra-Arterial; Injections, Intravenous; Male; Microspheres; Neoplasm Transplantation; Nitrosourea Compounds; Rats; Rats, Wistar; Taurine; Time Factors; Tissue Distribution	1995
Long-term survival in two cases of colorectal carcinoma following a new chemotherapy regimen and subsequent metastasectomy. European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 1995, Volume: 21, Issue:5 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colorectal Neoplasms; Female; Fluorouracil; Humans; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Nitrosourea Compounds; Taurine	1995
5-Fluorouracil causes alterations in the pharmacokinetic profile of tauromustine in NMRI mice. Cancer chemotherapy and pharmacology, 1994, Volume: 34, Issue:1 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Blood Proteins; Chromatography, High Pressure Liquid; Drug Administration Schedule; Drug Interactions; Fluorouracil; Male; Mice; Mice, Inbred Strains; Nitrosourea Compounds; Protein Binding; Taurine	1994
Fluorimetric determination of tauromustine (a novel antitumour agent) in formulations and biological fluids. Journal of pharmaceutical and biomedical analysis, 1993, Volume: 11, Issue:8 Topics: Antineoplastic Agents; Calibration; Chemistry, Pharmaceutical; Humans; Hydrogen-Ion Concentration; Nitrosourea Compounds; Regression Analysis; Sensitivity and Specificity; Spectrometry, Fluorescence; Tablets; Taurine	1993
Tauromustine (TCNU) combined with 5-fluorouracil and leucovorin in the treatment of advanced colon cancer. European journal of cancer (Oxford, England : 1990), 1993, Volume: 29A, Issue:13 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Nitrosourea Compounds; Taurine; Treatment Outcome	1993
Pre-clinical evaluation of a novel chloroethylating agent, Clomesone. British journal of cancer, 1993, Volume: 67, Issue:3 Topics: Animals; Antineoplastic Agents; Bone Marrow; Drug Screening Assays, Antitumor; In Vitro Techniques; Mesylates; Mice; Mice, Inbred Strains; Nitrosourea Compounds; Streptozocin; Taurine; Tumor Cells, Cultured	1993
Tauromustine is more effective than conventional chemotherapy in the treatment of colonic tumors. Diseases of the colon and rectum, 1993, Volume: 36, Issue:4 Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Colonic Neoplasms; Drug Therapy, Combination; Fluorouracil; Leucovorin; Male; Mice; Mice, Inbred BALB C; Nitrosourea Compounds; Taurine	1993
Measurement and characterization of the denitrosation of tauromustine and related nitrosoureas by glutathione transferases in liver cytosol from various species. Carcinogenesis, 1993, Volume: 14, Issue:6 Topics: Animals; Antineoplastic Agents; Chromatography, High Pressure Liquid; Cytosol; Dogs; Enzyme Induction; Female; Glutathione Transferase; Hydrogen-Ion Concentration; In Vitro Techniques; Liver; Male; Mice; Mice, Inbred Strains; Nitrosourea Compounds; Phenobarbital; Rats; Rats, Sprague-Dawley; Taurine; Temperature	1993
Chromosome aberrations and pharmacokinetics in patients receiving tauromustine as either a single or a repeated dose. Cancer chemotherapy and pharmacology, 1996, Volume: 38, Issue:4 Topics: Antineoplastic Agents; Chromosome Aberrations; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Lung Neoplasms; Nitrosourea Compounds; Taurine	1996
TCNU in colorectal cancer. How many patients are needed to demonstrate that a drug doesn't work? Annals of oncology : official journal of the European Society for Medical Oncology, 1996, Volume: 7, Issue:2 Topics: Antineoplastic Agents; Clinical Trials as Topic; Colorectal Neoplasms; Humans; Nitrosourea Compounds; Survival Rate; Taurine; Treatment Failure	1996
Metabolism of tauromustine in liver and lung microsomes from various species. Xenobiotica; the fate of foreign compounds in biological systems, 1999, Volume: 29, Issue:8 Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2A6; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Cytochromes; Dogs; Female; Humans; Lung; Male; Methylcholanthrene; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred Strains; Microsomes; Microsomes, Liver; Mixed Function Oxygenases; Nitrosourea Compounds; Oxidoreductases, N-Demethylating; Phenobarbital; Pregnenolone; Rats; Rats, Sprague-Dawley; Species Specificity; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Taurine; Testosterone	1999