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1-(2-chloroethyl)-3-(2-(dimethylaminosulfonyl)ethyl)-1-nitrosourea and fluorouracil

1-(2-chloroethyl)-3-(2-(dimethylaminosulfonyl)ethyl)-1-nitrosourea has been researched along with fluorouracil in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Franklin, HR; McVie, JG; Taal, BG; ten Bokkel Huinink, WW1
Boot, H; Gortzak, E; Taal, BG; Van den Hout, BM; Zoetmulder, FA1
Bibby, MC; Hill, SR1
Rodenhuis, S; Taal, BG; Ten Bokkel Huinink, WW2
Chaudry, IH; Graffner, HO; Milsom, JW; Singh, G1
Alderson, D; Denton, G; Grace, RH; Hardcastle, JD; Lauri, H; Mansi, JL; Nordle, O; Smyth, JF; Wählby, S; Yosef, HM1

Trials

2 trial(s) available for 1-(2-chloroethyl)-3-(2-(dimethylaminosulfonyl)ethyl)-1-nitrosourea and fluorouracil

ArticleYear
Combination chemotherapy with tauromustine (TCNU), 5-fluorouracil and leucovorin in advanced colorectal carcinoma: a dose-finding study.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1993, Volume: 4, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Dose-Response Relationship, Drug; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Nitrosourea Compounds; Prognosis; Taurine

1993
Two phase III trials of tauromustine (TCNU) in advanced colorectal cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1995, Volume: 6, Issue:9

    Topics: Aged; Antineoplastic Agents; Colorectal Neoplasms; Female; Fluorouracil; Humans; Male; Middle Aged; Nitrosourea Compounds; Prognosis; Quality of Life; Regression Analysis; Survival Rate; Taurine; Treatment Failure

1995

Other Studies

5 other study(ies) available for 1-(2-chloroethyl)-3-(2-(dimethylaminosulfonyl)ethyl)-1-nitrosourea and fluorouracil

ArticleYear
5-Fluorouracil plus tauromustine in advanced colorectal cancer: unexpected negative results.
    European journal of cancer (Oxford, England : 1990), 1990, Volume: 26, Issue:7

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Female; Fluorouracil; Humans; Male; Middle Aged; Nitrosourea Compounds; Taurine

1990
Long-term survival in two cases of colorectal carcinoma following a new chemotherapy regimen and subsequent metastasectomy.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 1995, Volume: 21, Issue:5

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colorectal Neoplasms; Female; Fluorouracil; Humans; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Nitrosourea Compounds; Taurine

1995
5-Fluorouracil causes alterations in the pharmacokinetic profile of tauromustine in NMRI mice.
    Cancer chemotherapy and pharmacology, 1994, Volume: 34, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Blood Proteins; Chromatography, High Pressure Liquid; Drug Administration Schedule; Drug Interactions; Fluorouracil; Male; Mice; Mice, Inbred Strains; Nitrosourea Compounds; Protein Binding; Taurine

1994
Tauromustine (TCNU) combined with 5-fluorouracil and leucovorin in the treatment of advanced colon cancer.
    European journal of cancer (Oxford, England : 1990), 1993, Volume: 29A, Issue:13

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Nitrosourea Compounds; Taurine; Treatment Outcome

1993
Tauromustine is more effective than conventional chemotherapy in the treatment of colonic tumors.
    Diseases of the colon and rectum, 1993, Volume: 36, Issue:4

    Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Colonic Neoplasms; Drug Therapy, Combination; Fluorouracil; Leucovorin; Male; Mice; Mice, Inbred BALB C; Nitrosourea Compounds; Taurine

1993