Compounds > 1-(2-chloroethyl)-1-nitrosourea
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1-(2-chloroethyl)-1-nitrosourea and o-(6)-methylguanine

1-(2-chloroethyl)-1-nitrosourea has been researched along with o-(6)-methylguanine in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19904 (66.67)18.7374
1990's2 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dolan, ME; Erickson, LC; Hora, NK; Pegg, AE1
Bresnick, E; Ding, R; Eastman, A; Ghosh, K1
Babich, MA; Day, RS; Hurst-Calderone, S; Yarosh, DB1
Brent, TP1
Berger, SJ; Donovan, C; Gerson, SL; Varnes, ME1
Bailey, JA; Cooper, DP; Deans, B; Elder, RH; Heeran, MC; Jansen, JG; Margison, GP; Mynett, KJ; Rafferty, JA; van Zeeland, AA; Watson, AJ; Weeks, RJ; Wijnhoven, SW; Willington, MA1

Other Studies

6 other study(ies) available for 1-(2-chloroethyl)-1-nitrosourea and o-(6)-methylguanine

ArticleYear
Effect of O6-methylguanine on DNA interstrand cross-link formation by chloroethylnitrosoureas and 2-chloroethyl(methylsulfonyl)methanesulfonate.
    Cancer research, 1988, Jul-01, Volume: 48, Issue:13

    Topics: Cell Division; Cell Survival; Cross-Linking Reagents; DNA Damage; DNA Repair; Ethylnitrosourea; Guanine; Humans; Lomustine; Mesylates; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Tumor Cells, Cultured

1988
DNA-mediated transfer and expression of a human DNA repair gene that demethylates O6-methylguanine.
    Molecular and cellular biology, 1985, Volume: 5, Issue:11

    Topics: Animals; Cell Line; Cricetinae; Cricetulus; DNA Repair; DNA Restriction Enzymes; Drug Resistance; Ethylnitrosourea; Female; Genes; Guanine; Humans; Liver; Methyltransferases; Mycophenolic Acid; O(6)-Methylguanine-DNA Methyltransferase; Ovary; Transformation, Genetic

1985
Inactivation of O6-methylguanine-DNA methyltransferase and sensitization of human tumor cells to killing by chloroethylnitrosourea by O6-methylguanine as a free base.
    Cancer research, 1986, Volume: 46, Issue:4 Pt 1

    Topics: Cell Survival; DNA Repair; Ethylnitrosourea; Fibroblasts; Guanine; Humans; Methyltransferases; Neoplasms; O(6)-Methylguanine-DNA Methyltransferase; Substrate Specificity

1986
Suppression of cross-link formation in chloroethylnitrosourea-treated DNA by an activity in extracts of human leukemic lymphoblasts.
    Cancer research, 1984, Volume: 44, Issue:5

    Topics: Antineoplastic Agents; Cell Line; DNA, Neoplasm; Ethylnitrosourea; Guanine; Humans; Kinetics; Leukemia, Lymphoid; Methylnitrosourea; Methyltransferases; Nitrosourea Compounds; O(6)-Methylguanine-DNA Methyltransferase

1984
Combined depletion of O6-alkylguanine-DNA alkyltransferase and glutathione to modulate nitrosourea resistance in breast cancer.
    Biochemical pharmacology, 1994, Aug-03, Volume: 48, Issue:3

    Topics: Breast Neoplasms; Carmustine; Cell Line; Cell Survival; Drug Resistance; Ethylnitrosourea; Glutathione; Glutathione Transferase; Guanine; Humans; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase

1994
Alkylpurine-DNA-N-glycosylase knockout mice show increased susceptibility to induction of mutations by methyl methanesulfonate.
    Molecular and cellular biology, 1998, Volume: 18, Issue:10

    Topics: Animals; Bone Marrow Cells; Cells, Cultured; Dacarbazine; DNA Glycosylases; Erythrocytes; Ethylnitrosourea; Female; Fibroblasts; Guanine; Hypoxanthine Phosphoribosyltransferase; Leukocyte Count; Liver; Male; Methyl Methanesulfonate; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Knockout; Mutagens; Mutation; N-Glycosyl Hydrolases; Temozolomide

1998