Compounds > 1-(2-chloroethyl)-1-nitrosourea
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1-(2-chloroethyl)-1-nitrosourea and fluorouracil

1-(2-chloroethyl)-1-nitrosourea has been researched along with fluorouracil in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19903 (50.00)18.7374
1990's3 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Atassi, G; Bibby, MC; Double, JA; Dumont, P; McCormick, JE; McElhinney, RS; Pratesi, G; Radacic, M1
McCormick, JE; McElhinney, RS1
Bibby, MC; Double, JA; McCormick, JE; McElhinney, RS1
Bibby, MC; Loadman, PM; Matthew, AM; McCormick, JE; McElhinney, RS1
Bibby, MC; Double, JA; Dumont, P; McCormick, JE; McElhinney, RS; Radacic, M1
Bibby, MC; Margison, GP; McElhinney, RS; Rafferty, JA; Thompson, MJ1

Other Studies

6 other study(ies) available for 1-(2-chloroethyl)-1-nitrosourea and fluorouracil

ArticleYear
Nucleoside analogues: 8. Some isomers of B.3839, the original 5-fluorouracil/nitrosourea molecular combination, and their effect on colon, breast and lung tumours in mice.
    Anti-cancer drug design, 1989, Volume: 4, Issue:1

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Colonic Neoplasms; Drug Screening Assays, Antitumor; Ethylnitrosourea; Fluorouracil; Isomerism; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Nitrosourea Compounds

1989
Nucleoside analogues. 4. Molecular combinations of anti-tumour drugs: synthesis of 5-fluorouracil seco-nucleosides with N-(2-chloroethyl)-N-nitrosourea residues by using aryl N-nitrosocarbamates.
    Anti-cancer drug design, 1986, Volume: 1, Issue:2

    Topics: Antineoplastic Agents; Ethylnitrosourea; Fluorouracil; Nucleosides

1986
Nucleoside analogues. 5. Molecular combination of anti-cancer drugs: activity of 5-fluorouracil/nitrosourea combinations against mouse colon tumours.
    Anti-cancer drug design, 1986, Volume: 1, Issue:2

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Ethylnitrosourea; Fluorouracil; Mice; Nucleosides; Structure-Activity Relationship

1986
Pharmacokinetics and anti-tumour activity of B.4152, a reactive molecular combination of 5-fluorouracil and N-(2-chloroethyl)-N-nitrosourea, and its uracil analogue.
    Anti-cancer drug design, 1996, Volume: 11, Issue:2

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cells, Cultured; Ethylnitrosourea; Fluorouracil; Male; Mice

1996
Nucleoside analogs. 14. The synthesis of antitumor activity in mice of molecular combinations of 5-fluorouracil and N-(2-Chloroethyl)-N-nitrosourea moieties separated by a three-carbon chain.
    Journal of medicinal chemistry, 1996, Mar-29, Volume: 39, Issue:7

    Topics: Animals; Antineoplastic Agents; Colonic Neoplasms; Ethylnitrosourea; Fluorouracil; Mammary Neoplasms, Experimental; Mice; Nucleosides

1996
Influence of O6-benzylguanine on the anti-tumour activity and normal tissue toxicity of 1,3-bis(2-chloroethyl)-1-nitrosourea and molecular combinations of 5-fluorouracil and 2-chloroethyl-1-nitrosourea in mice.
    British journal of cancer, 1999, Volume: 79, Issue:9-10

    Topics: Animals; Antineoplastic Agents, Alkylating; Carmustine; Colony-Forming Units Assay; Drug Combinations; Drug Resistance, Neoplasm; Enzyme Inhibitors; Ethylnitrosourea; Fluorouracil; Guanine; Humans; Male; Mice; Mice, Nude; O(6)-Methylguanine-DNA Methyltransferase; Tumor Stem Cell Assay

1999