1-(2,6-dimethylphenoxy)-2-(3,4-dimethoxyphenylethylamino)propane and verapamil

1-(2,6-dimethylphenoxy)-2-(3,4-dimethoxyphenylethylamino)propane has been researched along with verapamil in 3 studies

Compound Research Comparison

Studies (1-(2,6-dimethylphenoxy)-2-(3,4-dimethoxyphenylethylamino)propane)	Trials (1-(2,6-dimethylphenoxy)-2-(3,4-dimethoxyphenylethylamino)propane)	Recent Studies (post-2010) (1-(2,6-dimethylphenoxy)-2-(3,4-dimethoxyphenylethylamino)propane)	Studies (verapamil)	Trials (verapamil)	Recent Studies (post-2010) (verapamil)
36	1	9	17,621	1,527	2,067

Protein Interaction Comparison

Protein	Taxonomy	verapamil (IC50)
Solute carrier family 22 member 1	Homo sapiens (human)	6.8
Voltage-dependent L-type calcium channel subunit alpha-1F	Homo sapiens (human)	0.2
5-hydroxytryptamine receptor 4	Cavia porcellus (domestic guinea pig)	0.297
ATP-dependent translocase ABCB1	Mus musculus (house mouse)	2
ATP-dependent translocase ABCB1	Homo sapiens (human)	2.2346
Cytochrome P450 3A4	Homo sapiens (human)	3.8008
Alpha-2A adrenergic receptor	Homo sapiens (human)	0.579
5-hydroxytryptamine receptor 1A	Rattus norvegicus (Norway rat)	3.02
ATP-dependent translocase ABCB1	Mus musculus (house mouse)	10
Catechol O-methyltransferase	Homo sapiens (human)	0.2
Potassium voltage-gated channel subfamily A member 3	Homo sapiens (human)	8
Histamine H2 receptor	Homo sapiens (human)	2.59
5-hydroxytryptamine receptor 2A	Homo sapiens (human)	0.442
5-hydroxytryptamine receptor 2C	Homo sapiens (human)	0.297
5-hydroxytryptamine receptor 1B	Rattus norvegicus (Norway rat)	3.02
Sodium-dependent serotonin transporter	Homo sapiens (human)	0.24
Multidrug resistance-associated protein 1	Homo sapiens (human)	5.598
D(3) dopamine receptor	Homo sapiens (human)	0.186
5-hydroxytryptamine receptor 2B	Homo sapiens (human)	0.165
5-hydroxytryptamine receptor 7	Cavia porcellus (domestic guinea pig)	6.8
Voltage-dependent L-type calcium channel subunit alpha-1D	Homo sapiens (human)	0.2
Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)	0.3945
Voltage-dependent L-type calcium channel subunit alpha-1S	Homo sapiens (human)	0.2
Voltage-dependent L-type calcium channel subunit alpha-1C	Homo sapiens (human)	0.175
Broad substrate specificity ATP-binding cassette transporter ABCG2	Homo sapiens (human)	1.1934

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (66.67)	29.6817
2010's	1 (33.33)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Du, LP; Li, MY; Tsai, KC; Xia, L; You, QD	1
Hu, XD; Qian, JQ	1
Hu, Y; Lu, S; Tang, X; Wu, J; Xu, G; Xu, Y; Zhi, F	1

Other Studies

3 other study(ies) available for 1-(2,6-dimethylphenoxy)-2-(3,4-dimethoxyphenylethylamino)propane and verapamil

Article	Year
The pharmacophore hypotheses of I(Kr) potassium channel blockers: novel class III antiarrhythmic agents. Bioorganic & medicinal chemistry letters, 2004, Sep-20, Volume: 14, Issue:18 Topics: Anti-Arrhythmia Agents; Models, Biological; Models, Molecular; Potassium Channel Blockers; Potassium Channels; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2004
DDPH inhibited L-type calcium current and sodium current in single ventricular myocyte of guinea pig. Acta pharmacologica Sinica, 2001, Volume: 22, Issue:5 Topics: Animals; Anti-Arrhythmia Agents; Calcium Channels, L-Type; Cell Separation; Electrophysiology; Guinea Pigs; Mexiletine; Muscle Cells; Patch-Clamp Techniques; Phenethylamines; Sodium Channels; Verapamil	2001
Overcoming multidrug-resistance in vitro and in vivo using the novel P-glycoprotein inhibitor 1416. Bioscience reports, 2012, Volume: 32, Issue:6 Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Survival; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; K562 Cells; KB Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Phenethylamines; Verapamil; Vinblastine	2012