1-(2',5'-bis-o-(tert-butyldimethylsilylribofuranosyl)-3-n-methylthymine)-3'-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide) has been researched along with efavirenz in 1 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (100.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Balzarini, J; Camarasa, MJ; Chamorro, C; Gago, F; Lobatón, E; Pelemans, H; Pérez, C; Pérez-Pérez, MJ; Rodríguez-Barrios, F; San-Félix, A; Velázquez, S | 1 |
1 other study(ies) available for 1-(2',5'-bis-o-(tert-butyldimethylsilylribofuranosyl)-3-n-methylthymine)-3'-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide) and efavirenz
Article | Year |
---|---|
Identification of a putative binding site for [2',5'-bis-O-(tert-butyldimethylsilyl)-beta-D-ribofuranosyl]-3'-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide)thymine (TSAO) derivatives at the p51-p66 interface of HIV-1 reverse transcriptase.
Topics: Amino Acid Substitution; Anti-HIV Agents; Binding Sites; Cell Line; HIV Reverse Transcriptase; HIV-1; Humans; Models, Molecular; Molecular Conformation; Molecular Structure; Mutagenesis, Site-Directed; Protein Conformation; Protein Structure, Secondary; Protein Subunits; Recombinant Proteins; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Spiro Compounds; Static Electricity; Structure-Activity Relationship; Thymidine | 2001 |