Page last updated: 2024-08-24

1-(2',5'-bis-o-(tert-butyldimethylsilylribofuranosyl)-3-n-methylthymine)-3'-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide) and delavirdine

1-(2',5'-bis-o-(tert-butyldimethylsilylribofuranosyl)-3-n-methylthymine)-3'-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide) has been researched along with delavirdine in 2 studies

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Balzarini, J; Camarasa, MJ; Chamorro, C; Gago, F; Lobatón, E; Pelemans, H; Pérez, C; Pérez-Pérez, MJ; Rodríguez-Barrios, F; San-Félix, A; Velázquez, S1
Balzarini, J; Camarasa, MJ; De Clercq, E; Karlsson, A; Pérez-Pérez, MJ; San-Félix, A; Vélazquez, S1

Other Studies

2 other study(ies) available for 1-(2',5'-bis-o-(tert-butyldimethylsilylribofuranosyl)-3-n-methylthymine)-3'-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide) and delavirdine

ArticleYear
Identification of a putative binding site for [2',5'-bis-O-(tert-butyldimethylsilyl)-beta-D-ribofuranosyl]-3'-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide)thymine (TSAO) derivatives at the p51-p66 interface of HIV-1 reverse transcriptase.
    Journal of medicinal chemistry, 2001, Jun-07, Volume: 44, Issue:12

    Topics: Amino Acid Substitution; Anti-HIV Agents; Binding Sites; Cell Line; HIV Reverse Transcriptase; HIV-1; Humans; Models, Molecular; Molecular Conformation; Molecular Structure; Mutagenesis, Site-Directed; Protein Conformation; Protein Structure, Secondary; Protein Subunits; Recombinant Proteins; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Spiro Compounds; Static Electricity; Structure-Activity Relationship; Thymidine

2001
Suppression of the breakthrough of human immunodeficiency virus type 1 (HIV-1) in cell culture by thiocarboxanilide derivatives when used individually or in combination with other HIV-1-specific inhibitors (i.e., TSAO derivatives).
    Proceedings of the National Academy of Sciences of the United States of America, 1995, Jun-06, Volume: 92, Issue:12

    Topics: Antiviral Agents; Base Sequence; Carboxin; Cell Line; Delavirdine; DNA Primers; Drug Antagonism; HIV Reverse Transcriptase; HIV-1; Humans; Indoles; Molecular Sequence Data; Mutation; Piperazines; Reverse Transcriptase Inhibitors; Spiro Compounds; Thymidine

1995