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1-(2-(4-aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine and sumatriptan

1-(2-(4-aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine has been researched along with sumatriptan in 1 studies

Compound Research Comparison

Studies
(1-(2-(4-aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine)
Trials
(1-(2-(4-aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine)
Recent Studies (post-2010)
(1-(2-(4-aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine)
Studies
(sumatriptan)
Trials
(sumatriptan)
Recent Studies (post-2010) (sumatriptan)
530152,405461480

Protein Interaction Comparison

ProteinTaxonomy1-(2-(4-aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine (IC50)sumatriptan (IC50)
5-hydroxytryptamine receptor 3EHomo sapiens (human)0.0073
5-hydroxytryptamine receptor 3BHomo sapiens (human)0.0073
5-hydroxytryptamine receptor 1AHomo sapiens (human)0.4497
Carboxypeptidase MHomo sapiens (human)0.02
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)0.64
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.722
Alpha-1D adrenergic receptorRattus norvegicus (Norway rat)0.64
5-hydroxytryptamine receptor 1DHomo sapiens (human)0.3091
5-hydroxytryptamine receptor 1BHomo sapiens (human)0.0131
5-hydroxytryptamine receptor 2AHomo sapiens (human)7.9433
5-hydroxytryptamine receptor 2CHomo sapiens (human)3.9753
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)0.804
5-hydroxytryptamine receptor 1DRattus norvegicus (Norway rat)0.061
5-hydroxytryptamine receptor 1EHomo sapiens (human)5.5
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)0.64
5-hydroxytryptamine receptor 3AHomo sapiens (human)0.0078
5-hydroxytryptamine receptor 5AHomo sapiens (human)0.5012
5-hydroxytryptamine receptor 1DSus scrofa (pig)0.02
5-hydroxytryptamine receptor 1AMus musculus (house mouse)0.45
5-hydroxytryptamine receptor 3DHomo sapiens (human)0.0073
5-hydroxytryptamine receptor 3CHomo sapiens (human)0.0073
Multidrug and toxin extrusion protein 1Homo sapiens (human)6.7

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bobirnac, I; Schoeffter, P1

Other Studies

1 other study(ies) available for 1-(2-(4-aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine and sumatriptan

ArticleYear
5-Hydroxytryptamine 5-HT1D receptors mediating inhibition of cyclic AMP accumulation in Madin-Darby canine kidney (MDCK) cells.
    Naunyn-Schmiedeberg's archives of pharmacology, 1995, Volume: 352, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Alprostadil; Animals; Cells, Cultured; Cyclic AMP; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Epithelial Cells; Epithelium; Ketanserin; Kidney Cortex; Methiothepin; Oxadiazoles; Pertussis Toxin; Piperazines; Propranolol; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Structure-Activity Relationship; Sumatriptan; Virulence Factors, Bordetella; Yohimbine

1995