Page last updated: 2024-09-03

1-(2-(4-aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine and risperidone

1-(2-(4-aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine has been researched along with risperidone in 3 studies

Compound Research Comparison

Studies
(1-(2-(4-aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine)
Trials
(1-(2-(4-aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine)
Recent Studies (post-2010)
(1-(2-(4-aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine)
Studies
(risperidone)
Trials
(risperidone)
Recent Studies (post-2010) (risperidone)
530156,9241,5052,477

Protein Interaction Comparison

ProteinTaxonomy1-(2-(4-aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine (IC50)risperidone (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.015
5-hydroxytryptamine receptor 2CRattus norvegicus (Norway rat)0.0027
Alpha-2A adrenergic receptorHomo sapiens (human)0.0097
Cytochrome P450 2D6Homo sapiens (human)5.2734
Angiotensin-converting enzymeOryctolagus cuniculus (rabbit)4.1901
D(2) dopamine receptorHomo sapiens (human)0.0167
5-hydroxytryptamine receptor 2ARattus norvegicus (Norway rat)0.0991
Alpha-2B adrenergic receptorHomo sapiens (human)0.026
Alpha-2C adrenergic receptorHomo sapiens (human)0.0096
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.799
D(1A) dopamine receptorHomo sapiens (human)0.479
Histamine H2 receptorHomo sapiens (human)1.483
Alpha-1D adrenergic receptorHomo sapiens (human)0.01
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.0016
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.0057
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)0.799
5-hydroxytryptamine receptor 2BRattus norvegicus (Norway rat)0.0027
5-hydroxytryptamine receptor 2C Mus musculus (house mouse)0.0015
Alpha-1A adrenergic receptorHomo sapiens (human)0.0105
5-hydroxytryptamine receptor 2AMus musculus (house mouse)0.0015
Histamine H1 receptorHomo sapiens (human)0.4515
D(3) dopamine receptorHomo sapiens (human)0.024
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.023
D(2) dopamine receptorMus musculus (house mouse)0.023
D(2) dopamine receptorRattus norvegicus (Norway rat)0.0154
5-hydroxytryptamine receptor 2BMus musculus (house mouse)0.0015
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)0.6303
5-hydroxytryptamine receptor 1AMus musculus (house mouse)0.43
Nuclear receptor subfamily 3 group C member 3 Bos taurus (cattle)4.1901
Multidrug and toxin extrusion protein 1Homo sapiens (human)1.6

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's2 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Audinot, V; Chaput, C; Conte, C; Gavaudan, S; Millan, MJ; Newman-Tancredi, A; Touzard, M; Verrièle, L1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J1

Other Studies

3 other study(ies) available for 1-(2-(4-aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine and risperidone

ArticleYear
Agonist and antagonist actions of antipsychotic agents at 5-HT1A receptors: a [35S]GTPgammaS binding study.
    European journal of pharmacology, 1998, Aug-21, Volume: 355, Issue:2-3

    Topics: Animals; Antipsychotic Agents; CHO Cells; Cricetinae; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Agents; Sulfur Radioisotopes

1998
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
    Nature chemical biology, 2009, Volume: 5, Issue:10

    Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection

2009