1-(2-(4-aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine has been researched along with metergoline in 5 studies
| Studies (1-(2-(4-aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine) | Trials (1-(2-(4-aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine) | Recent Studies (post-2010) (1-(2-(4-aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine) | Studies (metergoline) | Trials (metergoline) | Recent Studies (post-2010) (metergoline) |
|---|---|---|---|---|---|
| 53 | 0 | 15 | 656 | 37 | 44 |
| Protein | Taxonomy | 1-(2-(4-aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine (IC50) | metergoline (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 0.0007 | |
| Bile salt export pump | Homo sapiens (human) | 10 | |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | 0.366 | |
| 5-hydroxytryptamine receptor 1A | Homo sapiens (human) | 0.0041 | |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 0.058 | |
| Cytochrome P450 2D6 | Homo sapiens (human) | 0.2 | |
| D(2) dopamine receptor | Homo sapiens (human) | 0.063 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 0.016 | |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | 0.189 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.0062 | |
| Substance-K receptor | Homo sapiens (human) | 4.071 | |
| D(1A) dopamine receptor | Homo sapiens (human) | 0.074 | |
| Acetylcholinesterase | Homo sapiens (human) | 1.344 | |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 0.366 | |
| Histamine H2 receptor | Homo sapiens (human) | 0.975 | |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | 0.136 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 0.0004 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 0.0007 | |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 0.0062 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 0.59 | |
| Histamine H1 receptor | Homo sapiens (human) | 4.133 | |
| D(3) dopamine receptor | Homo sapiens (human) | 0.0077 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 0.0004 | |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | 0.028 | |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | 0.063 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hamblin, MW; Monsma, FJ; Shen, Y; Sibley, DR; Ward, RP | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
| Fuller, RW; Molloy, BB; Snoddy, HD | 1 |
| Schechter, LE; Simansky, KJ | 1 |
5 other study(ies) available for 1-(2-(4-aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine and metergoline
| Article | Year |
|---|---|
Cloning and expression of a novel serotonin receptor with high affinity for tricyclic psychotropic drugs.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Blotting, Northern; Brain Chemistry; Cell Line; Cloning, Molecular; DNA; GTP-Binding Proteins; Lysergic Acid Diethylamide; Molecular Sequence Data; Polymerase Chain Reaction; Psychotropic Drugs; Rats; Receptors, Serotonin; RNA; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Transfection | 1993 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |
Central serotonin agonist actions of LY 165163, 1-(m-trifluoromethylphenyl)-4-(p-aminophenylethyl) piperazine, in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amides; Animals; Brain Chemistry; Corticosterone; Dose-Response Relationship, Drug; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Metergoline; Piperazines; Probenecid; Prolactin; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1986 |
Properties of some 1-arylpiperazines as antagonists of stereotyped behaviors mediated by central serotonergic receptors in rodents.
Topics: Animals; Brain; Dose-Response Relationship, Drug; Male; Metergoline; Mice; Motor Activity; Piperazines; Rats; Receptors, Serotonin; Serotonin Antagonists; Stereotyped Behavior; Syndrome; Thiazolidines; Thyrotropin-Releasing Hormone | 1988 |